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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hmga1

Z-value: 1.23

Motif logo

Transcription factors associated with Hmga1

Gene Symbol Gene ID Gene Info
ENSMUSG00000046711.9 high mobility group AT-hook 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556641_27556658-0.447.1e-03Click!

Activity profile of Hmga1 motif

Sorted Z-values of Hmga1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39007019 4.98 ENSMUST00000025966.4
cytochrome P450, family 2, subfamily c, polypeptide 55
chr19_-_8218832 3.88 ENSMUST00000113298.2
solute carrier family 22. member 29
chr10_+_87861309 3.74 ENSMUST00000122100.1
insulin-like growth factor 1
chr5_-_87092546 3.64 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr1_-_139608282 3.33 ENSMUST00000170441.2
complement factor H-related 3
chr1_-_150465563 2.98 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr1_-_162984519 2.96 ENSMUST00000028010.7
flavin containing monooxygenase 3
chr1_-_162898665 2.39 ENSMUST00000111510.1
ENSMUST00000045902.6
flavin containing monooxygenase 2
chr19_+_39510844 2.17 ENSMUST00000025968.4
cytochrome P450, family 2, subfamily c, polypeptide 39
chr8_+_45658666 2.12 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr5_-_87591582 2.07 ENSMUST00000031201.7
sulfotransferase family 1E, member 1
chr5_+_146079254 2.04 ENSMUST00000035571.8
cytochrome P450, family 3, subfamily a, polypeptide 59
chr9_+_55326913 1.85 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr6_-_59024340 1.84 ENSMUST00000173193.1
family with sequence similarity 13, member A
chr7_-_14254870 1.84 ENSMUST00000184731.1
ENSMUST00000076576.6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
chr8_+_45658273 1.81 ENSMUST00000153798.1
sorbin and SH3 domain containing 2
chr5_-_88527841 1.81 ENSMUST00000087033.3
immunoglobulin joining chain
chr9_-_48605147 1.80 ENSMUST00000034808.5
ENSMUST00000119426.1
nicotinamide N-methyltransferase
chr7_-_139582790 1.75 ENSMUST00000106095.2
NK6 homeobox 2
chr8_-_38661508 1.64 ENSMUST00000118896.1
sarcoglycan zeta
chr5_-_87140318 1.59 ENSMUST00000067790.6
ENSMUST00000113327.1
UDP glucuronosyltransferase 2 family, polypeptide B5
chr1_-_139781236 1.58 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr8_+_45658731 1.57 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr6_-_130231638 1.56 ENSMUST00000088011.4
ENSMUST00000112013.1
ENSMUST00000049304.7
killer cell lectin-like receptor, subfamily A, member 7
chr5_-_87337165 1.53 ENSMUST00000031195.2
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_-_4360256 1.52 ENSMUST00000027032.4
retinitis pigmentosa 1 (human)
chr5_-_86906937 1.51 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chr6_-_59024470 1.47 ENSMUST00000089860.5
family with sequence similarity 13, member A
chr3_+_19957240 1.41 ENSMUST00000108325.2
ceruloplasmin
chr16_+_56477838 1.40 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
ABI gene family, member 3 (NESH) binding protein
chr15_+_41447438 1.40 ENSMUST00000110297.2
ENSMUST00000090096.4
oxidation resistance 1
chr14_-_68582078 1.40 ENSMUST00000022641.7
ADAM-like, decysin 1
chr12_-_41485751 1.33 ENSMUST00000043884.4
leucine rich repeat protein 3, neuronal
chr10_+_4611971 1.32 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr1_-_140183283 1.21 ENSMUST00000111977.1
complement component factor h
chr1_+_180101144 1.20 ENSMUST00000133890.1
CDC42 binding protein kinase alpha
chr5_-_86676346 1.19 ENSMUST00000038448.6
transmembrane protease, serine 11b N terminal like
chr5_+_90518932 1.18 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr13_-_93637961 1.17 ENSMUST00000099309.4
betaine-homocysteine methyltransferase
chr5_-_87569023 1.16 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr7_-_68275098 1.14 ENSMUST00000135564.1
predicted gene 16157
chrX_+_59999436 1.13 ENSMUST00000033477.4
coagulation factor IX
chr17_+_43953191 1.12 ENSMUST00000044792.4
regulator of calcineurin 2
chr17_+_46428917 1.10 ENSMUST00000113465.3
cysteine-rich protein 3
chr1_-_30863256 1.10 ENSMUST00000088310.3
PHD finger protein 3
chr14_-_26534870 1.09 ENSMUST00000139075.1
ENSMUST00000102956.1
sarcolemma associated protein
chr18_-_38918642 1.09 ENSMUST00000040647.4
fibroblast growth factor 1
chr3_+_19957088 1.08 ENSMUST00000108328.1
ceruloplasmin
chr12_-_65073927 1.08 ENSMUST00000021332.8
FK506 binding protein 3
chr3_+_19957037 1.06 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr19_-_37330613 1.00 ENSMUST00000131070.1
insulin degrading enzyme
chr3_+_36159522 0.97 ENSMUST00000165956.2
DNA segment, Chr 3, ERATO Doi 254, expressed
chr15_+_41830921 0.95 ENSMUST00000166917.1
oxidation resistance 1
chr5_-_51567717 0.95 ENSMUST00000127135.1
ENSMUST00000151104.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr5_-_123666682 0.94 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chr14_+_51007911 0.94 ENSMUST00000022424.6
ribonuclease, RNase A family, 10 (non-active)
chr18_+_35770318 0.94 ENSMUST00000165299.1
predicted gene 16490
chr10_+_11343387 0.93 ENSMUST00000069106.4
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr1_+_4808237 0.93 ENSMUST00000131119.1
lysophospholipase 1
chr3_-_49757257 0.92 ENSMUST00000035931.7
protocadherin 18
chr6_-_138079916 0.91 ENSMUST00000171804.1
solute carrier family 15, member 5
chrX_-_165004829 0.89 ENSMUST00000114890.2
predicted gene, 17604
chr9_+_124121534 0.88 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr1_+_180109192 0.86 ENSMUST00000143176.1
ENSMUST00000135056.1
CDC42 binding protein kinase alpha
chr18_+_37400845 0.86 ENSMUST00000057228.1
protocadherin beta 9
chr19_+_24875679 0.85 ENSMUST00000073080.5
predicted gene 10053
chr3_+_116008220 0.85 ENSMUST00000106502.1
exostoses (multiple)-like 2
chrX_+_166344692 0.85 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
glycoprotein m6b
chr5_-_66080971 0.84 ENSMUST00000127275.1
ENSMUST00000113724.1
RNA binding motif protein 47
chr5_-_87424201 0.84 ENSMUST00000072818.5
UDP glucuronosyltransferase 2 family, polypeptide B38
chr10_+_34483400 0.82 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr16_-_59632520 0.81 ENSMUST00000118438.1
ADP-ribosylation factor-like 6
chr16_-_57754707 0.81 ENSMUST00000089332.4
collagen, type VIII, alpha 1
chr1_+_139501692 0.80 ENSMUST00000027615.5
coagulation factor XIII, beta subunit
chr1_-_140183404 0.80 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr5_+_92392585 0.80 ENSMUST00000126281.1
ADP-ribosyltransferase 3
chrX_-_17571563 0.78 ENSMUST00000177213.1
FUN14 domain containing 1
chrX_+_38772671 0.78 ENSMUST00000050744.5
RIKEN cDNA 6030498E09 gene
chr15_-_50890396 0.77 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chr17_+_43952999 0.77 ENSMUST00000177857.1
regulator of calcineurin 2
chr13_-_74376566 0.76 ENSMUST00000091481.2
zinc finger protein 72
chr12_+_59131473 0.74 ENSMUST00000177162.1
CTAGE family, member 5
chr2_-_77519565 0.73 ENSMUST00000111830.2
zinc finger protein 385B
chr15_+_44196135 0.73 ENSMUST00000038856.6
ENSMUST00000110289.3
thyrotropin releasing hormone receptor
chr2_+_71981184 0.73 ENSMUST00000090826.5
ENSMUST00000102698.3
Rap guanine nucleotide exchange factor (GEF) 4
chr7_+_135268579 0.73 ENSMUST00000097983.3
neuropeptide S
chr11_-_73324616 0.72 ENSMUST00000021119.2
aspartoacylase
chr4_+_21727726 0.72 ENSMUST00000102997.1
ENSMUST00000120679.1
ENSMUST00000108240.2
cyclin C
chr10_-_34207551 0.71 ENSMUST00000048010.7
dermatan sulfate epimerase
chrX_+_107255878 0.71 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr6_+_139843648 0.71 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr19_-_24861828 0.70 ENSMUST00000047666.4
phosphoglucomutase 5
chrM_+_3906 0.69 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr3_-_108536466 0.68 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
RIKEN cDNA 5330417C22 gene
chr13_-_85127514 0.68 ENSMUST00000179230.1
predicted gene 4076
chr16_+_14705832 0.68 ENSMUST00000023356.6
snail homolog 2 (Drosophila)
chr8_-_36732897 0.68 ENSMUST00000098826.3
deleted in liver cancer 1
chr12_+_59131286 0.67 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
CTAGE family, member 5
chr6_+_88724828 0.67 ENSMUST00000089449.2
monoglyceride lipase
chr4_+_11704439 0.67 ENSMUST00000108304.2
GTP binding protein (gene overexpressed in skeletal muscle)
chr7_-_80401707 0.67 ENSMUST00000120753.1
furin (paired basic amino acid cleaving enzyme)
chr9_-_101198999 0.66 ENSMUST00000066773.7
protein phosphatase 2, regulatory subunit B'', alpha
chr5_+_102481546 0.66 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr1_+_59482133 0.66 ENSMUST00000114246.2
ENSMUST00000037105.6
frizzled homolog 7 (Drosophila)
chr18_+_37477768 0.65 ENSMUST00000051442.5
protocadherin beta 16
chr2_+_20737306 0.65 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr1_+_180111339 0.65 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr19_+_5038826 0.65 ENSMUST00000053705.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr16_+_58670208 0.65 ENSMUST00000060077.5
coproporphyrinogen oxidase
chr3_-_121171678 0.65 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
RWD domain containing 3
chrX_-_70365052 0.64 ENSMUST00000101509.2
iduronate 2-sulfatase
chr5_-_66054499 0.63 ENSMUST00000145625.1
RNA binding motif protein 47
chr1_-_52490736 0.62 ENSMUST00000170269.1
Ngfi-A binding protein 1
chr10_+_34297421 0.62 ENSMUST00000047935.6
TSPY-like 4
chr18_-_15403680 0.62 ENSMUST00000079081.6
aquaporin 4
chr14_+_51884982 0.62 ENSMUST00000167984.1
methyltransferase like 17
chr17_+_32685610 0.61 ENSMUST00000168171.1
cytochrome P450, family 4, subfamily f, polypeptide 15
chr8_+_34115030 0.61 ENSMUST00000095345.3
membrane bound O-acyltransferase domain containing 4
chr18_+_37513652 0.60 ENSMUST00000061405.4
protocadherin beta 21
chr2_-_51149100 0.60 ENSMUST00000154545.1
ENSMUST00000017288.2
Rho family GTPase 3
chr2_-_86347764 0.60 ENSMUST00000099894.2
olfactory receptor 1055
chr9_+_7571396 0.59 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr19_-_12765447 0.58 ENSMUST00000112933.1
ciliary neurotrophic factor
chrX_-_93632113 0.57 ENSMUST00000006856.2
polymerase (DNA directed), alpha 1
chr3_-_152193803 0.57 ENSMUST00000050073.6
DnaJ (Hsp40) homolog, subfamily B, member 4
chr14_-_34503323 0.57 ENSMUST00000171343.1
bone morphogenetic protein receptor, type 1A
chr10_-_25200110 0.56 ENSMUST00000100012.2
A kinase (PRKA) anchor protein 7
chr19_+_26623419 0.56 ENSMUST00000176584.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_54538984 0.56 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr1_+_9848270 0.56 ENSMUST00000171265.1
serum/glucocorticoid regulated kinase 3
chr6_+_91684061 0.55 ENSMUST00000032185.7
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr2_+_137663424 0.55 ENSMUST00000134833.1
predicted gene 14064
chr12_+_110485710 0.55 ENSMUST00000084985.3
ENSMUST00000109832.1
protein phosphatase 2, regulatory subunit B (B56), gamma isoform
chr10_+_97482350 0.55 ENSMUST00000163448.2
decorin
chr12_+_55089202 0.54 ENSMUST00000021407.10
signal recognition particle 54A
chr1_-_162937225 0.54 ENSMUST00000178465.1
flavin containing monooxygenase 6
chr14_+_53683593 0.53 ENSMUST00000103663.4
T cell receptor alpha variable 4-4-DV10
chr17_-_37483543 0.53 ENSMUST00000016427.4
ENSMUST00000171139.2
histocompatibility 2, M region locus 2
chrX_-_23285532 0.52 ENSMUST00000115319.2
kelch-like 13
chr2_+_125866107 0.52 ENSMUST00000134337.1
ENSMUST00000094604.2
ENSMUST00000134798.1
galactokinase 2
chrX_+_109196750 0.52 ENSMUST00000139259.1
ENSMUST00000060013.3
predicted gene 6377
chr18_+_20665250 0.52 ENSMUST00000075312.3
transthyretin
chr6_-_99632376 0.52 ENSMUST00000176255.1
predicted gene 20696
chr4_+_105157339 0.51 ENSMUST00000064139.7
phosphatidic acid phosphatase type 2B
chr6_+_97929799 0.51 ENSMUST00000101123.3
microphthalmia-associated transcription factor
chr14_-_30353468 0.51 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr1_+_45311538 0.50 ENSMUST00000087883.6
collagen, type III, alpha 1
chr15_-_5108492 0.50 ENSMUST00000118365.2
caspase recruitment domain family, member 6
chr18_+_84088077 0.50 ENSMUST00000060223.2
zinc binding alcohol dehydrogenase, domain containing 2
chr7_+_67647405 0.49 ENSMUST00000032774.8
ENSMUST00000107471.1
tetratricopeptide repeat domain 23
chr4_+_147507600 0.49 ENSMUST00000063704.7
predicted gene 13152
chrX_-_17572241 0.48 ENSMUST00000176638.1
ENSMUST00000026016.6
FUN14 domain containing 1
chr6_+_17743582 0.48 ENSMUST00000000674.6
ENSMUST00000077080.2
suppression of tumorigenicity 7
chr16_+_27307489 0.48 ENSMUST00000066852.8
osteocrin
chr9_+_7692086 0.47 ENSMUST00000018767.7
matrix metallopeptidase 7
chr6_-_136875794 0.46 ENSMUST00000032342.1
matrix Gla protein
chr9_-_100506844 0.46 ENSMUST00000112874.3
non-catalytic region of tyrosine kinase adaptor protein 1
chr9_+_122888471 0.46 ENSMUST00000063980.6
zinc finger with KRAB and SCAN domains 7
chr19_-_12796108 0.46 ENSMUST00000038627.8
zinc finger protein 91
chr9_+_57521232 0.46 ENSMUST00000000090.6
cytochrome c oxidase subunit Va
chr5_-_87254804 0.46 ENSMUST00000075858.3
UDP glucuronosyltransferase 2 family, polypeptide B37
chr13_-_114388057 0.46 ENSMUST00000022286.6
NADH dehydrogenase (ubiquinone) Fe-S protein 4
chr19_-_38224096 0.45 ENSMUST00000067167.5
FRA10AC1 homolog (human)
chr7_+_67655414 0.45 ENSMUST00000107470.1
tetratricopeptide repeat domain 23
chr1_-_155417283 0.44 ENSMUST00000027741.5
xenotropic and polytropic retrovirus receptor 1
chr7_-_28302238 0.44 ENSMUST00000108315.3
delta-like 3 (Drosophila)
chr10_-_82285278 0.43 ENSMUST00000171401.1
RIKEN cDNA 4932415D10 gene
chr5_-_122354161 0.43 ENSMUST00000117263.1
ENSMUST00000049009.6
RAD9 homolog B
chr11_+_52232009 0.43 ENSMUST00000037324.5
ENSMUST00000166537.1
S-phase kinase-associated protein 1A
chrX_+_144688907 0.43 ENSMUST00000112843.1
zinc finger, CCHC domain containing 16
chr11_+_73350839 0.43 ENSMUST00000120137.1
olfactory receptor 20
chr17_-_32822200 0.43 ENSMUST00000179695.1
zinc finger protein 799
chrX_+_82948861 0.43 ENSMUST00000114000.1
dystrophin, muscular dystrophy
chr14_-_26971232 0.43 ENSMUST00000036570.4
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr8_-_60954726 0.42 ENSMUST00000110302.1
chloride channel 3
chr1_+_179961110 0.42 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr7_+_101663705 0.42 ENSMUST00000106998.1
ClpB caseinolytic peptidase B
chr11_-_79962374 0.42 ENSMUST00000108241.1
ENSMUST00000043152.5
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr1_-_155417394 0.41 ENSMUST00000111775.1
ENSMUST00000111774.1
xenotropic and polytropic retrovirus receptor 1
chr10_-_7956223 0.41 ENSMUST00000146444.1
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr18_-_56572888 0.41 ENSMUST00000174518.1
aldehyde dehydrogenase family 7, member A1
chr1_-_52499980 0.41 ENSMUST00000164747.1
Ngfi-A binding protein 1
chrM_+_9870 0.41 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr19_+_55742242 0.40 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
transcription factor 7 like 2, T cell specific, HMG box
chr10_+_97565436 0.40 ENSMUST00000038160.4
lumican
chr3_+_85574109 0.40 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
PET112 homolog (S. cerevisiae)
chr9_+_88581036 0.40 ENSMUST00000164661.2
tripartite motif-containing 43A
chr8_-_36613937 0.39 ENSMUST00000033923.7
deleted in liver cancer 1
chr12_+_98771018 0.39 ENSMUST00000021399.7
zinc finger CCCH type containing 14
chr1_-_9298499 0.39 ENSMUST00000132064.1
syntrophin, gamma 1
chr12_-_81421910 0.39 ENSMUST00000085319.3
a disintegrin and metallopeptidase domain 4
chr5_+_21372642 0.38 ENSMUST00000035799.5
fibrinogen-like protein 2
chr9_+_39993812 0.38 ENSMUST00000057161.3
olfactory receptor 978
chr1_+_58113136 0.38 ENSMUST00000040999.7
aldehyde oxidase 3
chr17_+_88626549 0.38 ENSMUST00000163588.1
ENSMUST00000064035.6
stonin 1
chrX_-_136741155 0.38 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
mortality factor 4 like 2
chr8_-_67974567 0.38 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr18_+_37504264 0.38 ENSMUST00000052179.6
protocadherin beta 20
chr15_-_58364148 0.38 ENSMUST00000068515.7
annexin A13
chr11_-_28339867 0.37 ENSMUST00000042595.6
predicted pseudogene 6685

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmga1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.5 5.0 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.4 2.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.4 3.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.3 2.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 3.9 GO:0015747 urate transport(GO:0015747)
0.2 1.7 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.9 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 0.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.9 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 1.2 GO:0000103 sulfate assimilation(GO:0000103)
0.2 2.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.7 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 2.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 1.3 GO:0060523 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.2 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.7 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.2 1.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 0.6 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2 0.8 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.2 0.6 GO:0048338 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.2 0.7 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.2 0.7 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.2 0.9 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.9 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.2 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.6 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.1 0.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.6 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.4 GO:0051030 snRNA transport(GO:0051030)
0.1 0.6 GO:0070295 renal water absorption(GO:0070295)
0.1 0.7 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.4 GO:1904173 negative regulation of mitotic cell cycle, embryonic(GO:0045976) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.1 3.6 GO:0046688 response to copper ion(GO:0046688)
0.1 0.5 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 1.4 GO:0046549 retinal cone cell development(GO:0046549)
0.1 3.0 GO:0017144 drug metabolic process(GO:0017144)
0.1 3.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.3 GO:0097402 neuroblast migration(GO:0097402)
0.1 1.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 0.8 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.9 GO:0046959 habituation(GO:0046959)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 1.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 1.9 GO:0007614 short-term memory(GO:0007614)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.5 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.6 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.2 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.7 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.2 GO:0051180 vitamin transport(GO:0051180)
0.0 1.0 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 4.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:1904348 negative regulation of gastro-intestinal system smooth muscle contraction(GO:1904305) regulation of small intestine smooth muscle contraction(GO:1904347) negative regulation of small intestine smooth muscle contraction(GO:1904348) small intestine smooth muscle contraction(GO:1990770)
0.0 0.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0001835 blastocyst hatching(GO:0001835) DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.1 GO:0046032 ADP catabolic process(GO:0046032)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0021852 pyramidal neuron migration(GO:0021852)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 3.2 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.5 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0048852 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) diencephalon morphogenesis(GO:0048852)
0.0 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 1.3 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280) negative regulation of autophagosome assembly(GO:1902902)
0.0 1.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.0 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.6 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.2 1.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 1.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.7 GO:0005914 spot adherens junction(GO:0005914)
0.1 0.9 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.3 GO:0097542 ciliary tip(GO:0097542)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.2 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 3.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 2.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.9 GO:0042641 actomyosin(GO:0042641)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0000805 X chromosome(GO:0000805)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 4.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.0 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.5 2.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5 5.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 3.9 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.4 1.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 2.0 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.4 1.2 GO:0008431 vitamin E binding(GO:0008431)
0.4 3.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 0.9 GO:0030977 taurine binding(GO:0030977)
0.3 2.0 GO:0001851 complement component C3b binding(GO:0001851)
0.3 0.8 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.3 3.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 9.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.7 GO:0019807 aspartoacylase activity(GO:0019807)
0.2 1.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 0.9 GO:2001070 starch binding(GO:2001070)
0.2 0.5 GO:0004335 galactokinase activity(GO:0004335)
0.2 0.5 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.0 GO:0043559 insulin binding(GO:0043559)
0.1 3.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 3.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:1902121 NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0004031 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 1.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.6 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.4 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 1.6 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.0 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.9 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 0.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 2.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 5.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 3.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases