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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hmga2

Z-value: 1.31

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Transcription factors associated with Hmga2

Gene Symbol Gene ID Gene Info
Hmga2
ENSMUSG00000056758.8 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_1204765270.057.7e-01Click!

Activity profile of Hmga2 motif

Sorted Z-values of Hmga2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41392356 14.20 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr6_+_41521782 12.77 ENSMUST00000070380.4
Prss2
protease, serine, 2
chr6_+_41458923 11.11 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr6_-_41035501 10.78 ENSMUST00000031931.5
2210010C04Rik
RIKEN cDNA 2210010C04 gene
chr6_+_41302265 7.85 ENSMUST00000031913.4
Try4
trypsin 4
chr6_-_40999479 6.61 ENSMUST00000166306.1
Gm2663
predicted gene 2663
chr6_+_78380700 2.67 ENSMUST00000101272.1
Reg3a
regenerating islet-derived 3 alpha
chr7_+_13733502 2.40 ENSMUST00000086148.6
Sult2a2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr9_-_65422773 2.23 ENSMUST00000065894.5
Slc51b
solute carrier family 51, beta subunit
chr7_-_14123042 1.68 ENSMUST00000098809.2
Sult2a3
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr17_-_43502773 1.66 ENSMUST00000024707.8
ENSMUST00000117137.1
Mep1a
meprin 1 alpha
chr19_+_39992424 1.66 ENSMUST00000049178.2
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_+_100845709 1.43 ENSMUST00000144623.1
Agpat9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr7_-_13989588 1.30 ENSMUST00000165167.1
ENSMUST00000108520.2
Sult2a4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr2_+_68104671 1.16 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr18_+_87756280 1.09 ENSMUST00000091776.5
Gm5096
predicted gene 5096
chr9_-_71168657 1.07 ENSMUST00000113570.1
Aqp9
aquaporin 9
chr15_-_82690499 1.07 ENSMUST00000100380.3
Cyp2d37-ps
cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene
chr14_-_36919513 0.97 ENSMUST00000182042.1
Ccser2
coiled-coil serine rich 2
chr16_-_43979050 0.92 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23
zinc finger, DHHC domain containing 23
chr11_+_62951191 0.88 ENSMUST00000035854.3
Cdrt4
CMT1A duplicated region transcript 4
chrX_+_96456362 0.88 ENSMUST00000079322.5
ENSMUST00000113838.1
Heph
hephaestin
chr3_+_37348645 0.86 ENSMUST00000038885.3
Fgf2
fibroblast growth factor 2
chr16_+_30065333 0.85 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr16_-_36784924 0.78 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr12_+_57564111 0.78 ENSMUST00000101398.3
Ttc6
tetratricopeptide repeat domain 6
chr4_+_103114712 0.76 ENSMUST00000143417.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr14_-_36919314 0.74 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr7_-_12422751 0.73 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr16_+_33185045 0.73 ENSMUST00000039733.8
Osbpl11
oxysterol binding protein-like 11
chr10_-_93540016 0.71 ENSMUST00000016034.2
Amdhd1
amidohydrolase domain containing 1
chr17_+_55749978 0.71 ENSMUST00000025004.6
Emr4
EGF-like module containing, mucin-like, hormone receptor-like sequence 4
chr8_-_25091341 0.70 ENSMUST00000125466.1
Plekha2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr10_-_81014902 0.68 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
Gng7
guanine nucleotide binding protein (G protein), gamma 7
chr5_-_87140318 0.68 ENSMUST00000067790.6
ENSMUST00000113327.1
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr9_+_58488568 0.64 ENSMUST00000085658.4
6030419C18Rik
RIKEN cDNA 6030419C18 gene
chrX_-_140062712 0.63 ENSMUST00000133780.1
Nup62cl
nucleoporin 62 C-terminal like
chr7_-_42642547 0.62 ENSMUST00000098503.2
9830147E19Rik
RIKEN cDNA 9830147E19 gene
chr7_+_43440782 0.61 ENSMUST00000040227.1
Cldnd2
claudin domain containing 2
chr3_+_98222148 0.61 ENSMUST00000029469.4
Reg4
regenerating islet-derived family, member 4
chr5_+_21372642 0.60 ENSMUST00000035799.5
Fgl2
fibrinogen-like protein 2
chr2_-_122702615 0.59 ENSMUST00000005952.4
ENSMUST00000099457.3
Slc30a4
solute carrier family 30 (zinc transporter), member 4
chr2_+_25080316 0.59 ENSMUST00000044078.3
ENSMUST00000114380.2
Entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr11_-_116307168 0.58 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr9_-_97111117 0.55 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr15_-_63869297 0.54 ENSMUST00000089894.5
Gsdmc3
gasdermin C3
chr6_-_113719880 0.53 ENSMUST00000064993.5
Ghrl
ghrelin
chr16_+_96361749 0.53 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
Igsf5
immunoglobulin superfamily, member 5
chr12_-_16800886 0.53 ENSMUST00000161998.1
Greb1
gene regulated by estrogen in breast cancer protein
chr1_+_93235836 0.53 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr1_+_88055467 0.52 ENSMUST00000173325.1
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr2_-_98667264 0.51 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr19_+_40089688 0.51 ENSMUST00000068094.6
ENSMUST00000080171.2
Cyp2c50
cytochrome P450, family 2, subfamily c, polypeptide 50
chr2_-_75981967 0.51 ENSMUST00000099994.3
Ttc30a1
tetratricopeptide repeat domain 30A1
chrX_-_167264280 0.51 ENSMUST00000112170.1
ENSMUST00000133722.1
Tlr8
toll-like receptor 8
chr10_+_94550852 0.50 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3
transmembrane and coiled coil domains 3
chr9_+_122923050 0.50 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105
zinc finger protein 105
chr17_+_31208049 0.49 ENSMUST00000173776.1
Ubash3a
ubiquitin associated and SH3 domain containing, A
chr8_-_84176552 0.49 ENSMUST00000070102.5
Nanos3
nanos homolog 3 (Drosophila)
chr19_+_6184363 0.48 ENSMUST00000025699.2
ENSMUST00000113528.1
1700123I01Rik
RIKEN cDNA 1700123I01 gene
chr16_+_96361654 0.47 ENSMUST00000113794.1
Igsf5
immunoglobulin superfamily, member 5
chr15_-_63835949 0.47 ENSMUST00000089900.3
Gsdmc2
gasdermin C2
chr16_-_36784784 0.46 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr1_+_46066738 0.44 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr18_+_37447641 0.43 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr7_-_101869012 0.42 ENSMUST00000123321.1
Folr1
folate receptor 1 (adult)
chr9_-_8134294 0.42 ENSMUST00000037397.6
AK129341
cDNA sequence AK129341
chr3_+_135485605 0.42 ENSMUST00000029814.9
Manba
mannosidase, beta A, lysosomal
chr2_-_148732457 0.42 ENSMUST00000028926.6
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr4_+_57637816 0.40 ENSMUST00000150412.1
Gm20459
predicted gene 20459
chr8_+_61487715 0.39 ENSMUST00000034058.6
ENSMUST00000126575.1
Cbr4
carbonyl reductase 4
chr1_+_88055377 0.38 ENSMUST00000138182.1
ENSMUST00000113142.3
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr5_-_96164147 0.38 ENSMUST00000137207.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr13_+_49682191 0.38 ENSMUST00000172254.1
Iars
isoleucine-tRNA synthetase
chr4_-_120951664 0.37 ENSMUST00000106280.1
Zfp69
zinc finger protein 69
chr17_+_56628118 0.37 ENSMUST00000112979.2
Catsperd
catsper channel auxiliary subunit delta
chr10_+_69787431 0.36 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr2_-_110305730 0.36 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr9_-_123260776 0.36 ENSMUST00000068140.4
Tmem158
transmembrane protein 158
chr5_+_87000838 0.36 ENSMUST00000031186.7
Ugt2b35
UDP glucuronosyltransferase 2 family, polypeptide B35
chr16_+_96235801 0.35 ENSMUST00000113800.2
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr15_-_57265126 0.34 ENSMUST00000137764.1
ENSMUST00000022995.6
Slc22a22
solute carrier family 22 (organic cation transporter), member 22
chr15_+_12205009 0.34 ENSMUST00000038172.8
Mtmr12
myotubularin related protein 12
chr2_+_29124106 0.34 ENSMUST00000129544.1
Setx
senataxin
chr7_-_12422488 0.33 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr5_-_114858682 0.33 ENSMUST00000066959.4
Gm9936
predicted gene 9936
chr1_+_136676413 0.32 ENSMUST00000181491.1
Gm19705
predicted gene, 19705
chr7_+_49975228 0.32 ENSMUST00000107603.1
Nell1
NEL-like 1
chr18_+_37411674 0.32 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr17_+_73107982 0.32 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1
lysocardiolipin acyltransferase 1
chr11_+_83302817 0.32 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_101868667 0.31 ENSMUST00000150184.1
Folr1
folate receptor 1 (adult)
chr11_+_75999912 0.30 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr7_+_45526330 0.30 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr15_+_12205068 0.30 ENSMUST00000071993.6
Mtmr12
myotubularin related protein 12
chr14_+_25980039 0.30 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr9_+_13619990 0.29 ENSMUST00000159294.1
Maml2
mastermind like 2 (Drosophila)
chr1_-_144004142 0.28 ENSMUST00000127206.1
Rgs2
regulator of G-protein signaling 2
chr11_-_116306652 0.28 ENSMUST00000126731.1
Exoc7
exocyst complex component 7
chr2_+_27676440 0.28 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr10_+_25359798 0.27 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr5_+_43515513 0.27 ENSMUST00000167522.1
ENSMUST00000144558.1
ENSMUST00000076939.6
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr15_-_98145698 0.27 ENSMUST00000123626.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr2_-_80128834 0.27 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr6_-_128723046 0.26 ENSMUST00000112110.2
Klrb1
killer cell lectin-like receptor subfamily B member 1
chrX_-_147429189 0.25 ENSMUST00000033646.2
Il13ra2
interleukin 13 receptor, alpha 2
chr14_+_53491115 0.25 ENSMUST00000181210.1
ENSMUST00000183488.1
Trav6-5
T cell receptor alpha variable 6-5
chr10_-_130127055 0.24 ENSMUST00000074161.1
Olfr824
olfactory receptor 824
chr5_-_87424201 0.24 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chrX_+_7697131 0.24 ENSMUST00000049896.6
Gpkow
G patch domain and KOW motifs
chr1_+_132008285 0.23 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr16_+_32277449 0.23 ENSMUST00000155649.1
ENSMUST00000014218.8
ENSMUST00000171474.1
Rnf168
ring finger protein 168
chr13_-_56548534 0.22 ENSMUST00000062806.4
Lect2
leukocyte cell-derived chemotaxin 2
chr17_-_74459096 0.22 ENSMUST00000052124.7
Nlrc4
NLR family, CARD domain containing 4
chr14_-_100149764 0.22 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr5_+_90460889 0.21 ENSMUST00000031314.8
Alb
albumin
chr19_-_10525201 0.21 ENSMUST00000025570.6
Sdhaf2
succinate dehydrogenase complex assembly factor 2
chr5_-_17849783 0.21 ENSMUST00000170051.1
ENSMUST00000165232.1
Cd36
CD36 antigen
chr3_-_64287417 0.21 ENSMUST00000170244.1
ENSMUST00000176328.1
Vmn2r3
vomeronasal 2, receptor 3
chrX_-_36991724 0.19 ENSMUST00000152291.1
Sept6
septin 6
chr15_-_98145625 0.19 ENSMUST00000059112.5
Asb8
ankyrin repeat and SOCS box-containing 8
chr4_+_44756609 0.18 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr10_+_58446845 0.17 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr17_+_46772635 0.17 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chrM_+_9870 0.15 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_24612700 0.15 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr16_+_29579347 0.14 ENSMUST00000038867.6
ENSMUST00000161186.1
Opa1
optic atrophy 1
chr7_-_10495322 0.14 ENSMUST00000032551.7
Zik1
zinc finger protein interacting with K protein 1
chr2_-_102186322 0.13 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3
low density lipoprotein receptor class A domain containing 3
chr17_-_6961156 0.13 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr16_-_26371828 0.12 ENSMUST00000023154.2
Cldn1
claudin 1
chr17_-_50094277 0.12 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr15_-_103755439 0.12 ENSMUST00000078842.7
Mucl1
mucin-like 1
chr7_-_97738222 0.11 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr11_+_83942062 0.11 ENSMUST00000049257.7
Ddx52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr11_+_77462325 0.10 ENSMUST00000102493.1
Coro6
coronin 6
chr2_+_78051155 0.10 ENSMUST00000145972.1
4930440I19Rik
RIKEN cDNA 4930440I19 gene
chr7_+_129591859 0.09 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr7_-_133015248 0.08 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr17_+_8165501 0.08 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1op
Fgfr1 oncogene partner
chr4_-_25281801 0.08 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr6_+_35252724 0.06 ENSMUST00000136110.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr9_-_71485893 0.06 ENSMUST00000034720.5
Polr2m
polymerase (RNA) II (DNA directed) polypeptide M
chr16_+_29579331 0.06 ENSMUST00000160597.1
Opa1
optic atrophy 1
chr13_-_66852017 0.06 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr4_+_126286792 0.06 ENSMUST00000070132.6
Col8a2
collagen, type VIII, alpha 2
chr5_-_32133045 0.06 ENSMUST00000031308.6
Gm10463
predicted gene 10463
chr6_+_125039760 0.05 ENSMUST00000140131.1
ENSMUST00000032480.7
Ing4
inhibitor of growth family, member 4
chr6_+_21949571 0.05 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3
inhibitor of growth family, member 3
chr4_+_44756553 0.05 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr7_-_24724237 0.05 ENSMUST00000081657.4
Gm4763
predicted gene 4763
chr4_-_58912678 0.04 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180
expressed sequence AI314180
chrX_+_101640056 0.04 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr6_-_136401830 0.04 ENSMUST00000058713.7
E330021D16Rik
RIKEN cDNA E330021D16 gene
chr6_-_142473075 0.04 ENSMUST00000032371.7
Gys2
glycogen synthase 2
chr3_+_92365178 0.04 ENSMUST00000050397.1
Sprr2f
small proline-rich protein 2F
chr8_+_119344490 0.03 ENSMUST00000034300.6
Hsbp1
heat shock factor binding protein 1
chr8_-_3878549 0.03 ENSMUST00000011445.6
Cd209d
CD209d antigen
chr16_+_87454976 0.02 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16
ubiquitin specific peptidase 16
chr11_-_65159890 0.02 ENSMUST00000020855.3
ENSMUST00000108696.1
1700086D15Rik
RIKEN cDNA 1700086D15 gene
chr16_-_19286837 0.02 ENSMUST00000056727.4
Olfr164
olfactory receptor 164
chr5_-_31220491 0.02 ENSMUST00000031032.7
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr11_-_84069179 0.01 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr9_+_70012540 0.01 ENSMUST00000118198.1
ENSMUST00000119905.1
ENSMUST00000119413.1
ENSMUST00000140305.1
ENSMUST00000122087.1
Gtf2a2
general transcription factor II A, 2
chr14_-_62456286 0.00 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2
guanylate cyclase 1, soluble, beta 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmga2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 12.3 GO:0031000 response to caffeine(GO:0031000)
0.3 0.9 GO:0021558 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.3 1.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.2 2.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 1.2 GO:0042938 dipeptide transport(GO:0042938)
0.2 2.7 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 33.7 GO:0007586 digestion(GO:0007586)
0.2 0.9 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.7 GO:0006548 histidine catabolic process(GO:0006548)
0.1 1.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:2001183 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.5 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.7 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 2.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.8 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.4 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 0.3 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.8 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.6 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.3 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.5 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636) positive regulation of neuron maturation(GO:0014042)
0.0 0.4 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.3 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.2 GO:0005940 septin ring(GO:0005940)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.7 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 61.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.4 1.2 GO:0042936 dipeptide transporter activity(GO:0042936)
0.3 63.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 1.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 0.9 GO:0071820 N-box binding(GO:0071820)
0.2 1.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.2 0.5 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.5 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.1 0.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0051870 methotrexate binding(GO:0051870)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.0 2.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0048038 quinone binding(GO:0048038) NADPH binding(GO:0070402)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 24.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 12.8 REACTOME DEFENSINS Genes involved in Defensins
0.4 11.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes