Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Hoxa13

Z-value: 2.91

Motif logo

Transcription factors associated with Hoxa13

Gene Symbol Gene ID Gene Info
ENSMUSG00000038203.12 homeobox A13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa13mm10_v2_chr6_-_52260822_52260880-0.642.7e-05Click!

Activity profile of Hoxa13 motif

Sorted Z-values of Hoxa13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_61674094 26.99 ENSMUST00000098040.3
major urinary protein 18
chr4_-_61303802 23.50 ENSMUST00000125461.1
major urinary protein 14
chr4_-_61303998 22.16 ENSMUST00000071005.8
ENSMUST00000075206.5
major urinary protein 14
chr4_-_61439743 18.15 ENSMUST00000095049.4
major urinary protein 15
chr4_-_61519467 17.91 ENSMUST00000095051.5
ENSMUST00000107483.1
major urinary protein 16
chr4_-_61228271 17.78 ENSMUST00000072678.5
ENSMUST00000098042.3
major urinary protein 13
chr4_-_60070411 17.46 ENSMUST00000079697.3
ENSMUST00000125282.1
ENSMUST00000166098.1
major urinary protein 7
chr4_-_60662358 16.46 ENSMUST00000084544.4
ENSMUST00000098046.3
major urinary protein 11
chr4_-_61595871 16.41 ENSMUST00000107484.1
major urinary protein 17
chr4_-_60222580 16.34 ENSMUST00000095058.4
ENSMUST00000163931.1
major urinary protein 8
chr4_-_60582152 15.86 ENSMUST00000098047.2
major urinary protein 10
chr4_-_60139857 15.37 ENSMUST00000107490.4
ENSMUST00000074700.2
major urinary protein 2
chr4_-_60501903 15.34 ENSMUST00000084548.4
ENSMUST00000103012.3
ENSMUST00000107499.3
major urinary protein 1
chr4_-_60421933 14.77 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
major urinary protein 9
chr4_-_60741275 14.68 ENSMUST00000117932.1
major urinary protein 12
chr7_-_30924169 11.43 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr19_+_40089688 11.01 ENSMUST00000068094.6
ENSMUST00000080171.2
cytochrome P450, family 2, subfamily c, polypeptide 50
chr8_-_93279717 10.93 ENSMUST00000034178.8
carboxylesterase 1F
chr8_-_24576297 10.30 ENSMUST00000033953.7
ENSMUST00000121992.1
indoleamine 2,3-dioxygenase 2
chr8_-_5105232 10.17 ENSMUST00000023835.1
solute carrier family 10, member 2
chr4_+_63362443 8.73 ENSMUST00000075341.3
orosomucoid 2
chr15_+_6445320 7.64 ENSMUST00000022749.9
complement component 9
chr1_-_150465563 6.74 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr11_-_113710017 6.68 ENSMUST00000018871.1
cleavage and polyadenylation specific factor 4-like
chr12_-_103657095 5.22 ENSMUST00000152517.1
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr10_-_116896879 4.76 ENSMUST00000048229.7
myelin regulatory factor-like
chr8_+_45069137 4.65 ENSMUST00000067984.7
melatonin receptor 1A
chr1_+_59256906 4.50 ENSMUST00000160662.1
ENSMUST00000114248.2
cyclin-dependent kinase 15
chr16_+_56204313 4.37 ENSMUST00000160116.1
ENSMUST00000069936.7
interphotoreceptor matrix proteoglycan 2
chr5_-_87337165 4.27 ENSMUST00000031195.2
UDP glucuronosyltransferase 2 family, polypeptide A3
chr7_+_123462274 4.24 ENSMUST00000033023.3
aquaporin 8
chr19_+_24875679 4.22 ENSMUST00000073080.5
predicted gene 10053
chr1_-_97128249 4.12 ENSMUST00000027569.7
solute carrier organic anion transporter family, member 6c1
chr19_-_6067785 4.10 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
transmembrane 7 superfamily member 2
chr12_-_103657159 4.07 ENSMUST00000044159.6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr7_-_30944017 4.04 ENSMUST00000062620.7
hepcidin antimicrobial peptide
chr4_+_144893127 3.99 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr10_-_92375367 3.99 ENSMUST00000182870.1
predicted gene, 20757
chr10_-_115362191 3.85 ENSMUST00000092170.5
transmembrane protein 19
chr11_+_76904475 3.51 ENSMUST00000142166.1
transmembrane and immunoglobulin domain containing 1
chr8_+_45069374 3.47 ENSMUST00000130141.1
melatonin receptor 1A
chr12_-_104153846 3.44 ENSMUST00000085050.3
serine (or cysteine) peptidase inhibitor, clade A, member 3C
chr16_+_11405648 3.40 ENSMUST00000096273.2
sorting nexin 29
chr1_-_121332545 3.31 ENSMUST00000161068.1
insulin induced gene 2
chr17_+_31433054 3.25 ENSMUST00000136384.1
phosphodiesterase 9A
chr9_+_7445822 3.20 ENSMUST00000034497.6
matrix metallopeptidase 3
chr19_+_12633507 3.19 ENSMUST00000119960.1
glycine-N-acyltransferase
chr1_-_121332571 3.06 ENSMUST00000071064.6
insulin induced gene 2
chr11_-_11898092 3.05 ENSMUST00000178704.1
dopa decarboxylase
chr13_-_23934156 3.03 ENSMUST00000052776.2
histone cluster 1, H2ba
chr5_-_28467093 3.02 ENSMUST00000002708.3
sonic hedgehog
chr13_-_23914998 3.01 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr8_+_45507768 2.98 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
sorbin and SH3 domain containing 2
chr3_+_138313279 2.95 ENSMUST00000013455.6
ENSMUST00000106247.1
alcohol dehydrogenase 6A (class V)
chr9_-_76323559 2.93 ENSMUST00000063140.8
hypocretin (orexin) receptor 2
chr11_-_73324616 2.88 ENSMUST00000021119.2
aspartoacylase
chr3_+_96219858 2.86 ENSMUST00000073115.4
histone cluster 2, H2ab
chr15_+_62178175 2.85 ENSMUST00000182476.1
plasmacytoma variant translocation 1
chr3_-_10331358 2.81 ENSMUST00000065938.8
ENSMUST00000118410.1
inositol (myo)-1(or 4)-monophosphatase 1
chr19_+_12633303 2.76 ENSMUST00000044976.5
glycine-N-acyltransferase
chr9_-_44799179 2.71 ENSMUST00000114705.1
ENSMUST00000002100.7
transmembrane protein 25
chr8_+_95352258 2.70 ENSMUST00000034243.5
matrix metallopeptidase 15
chr1_-_193264006 2.69 ENSMUST00000161737.1
hydroxysteroid 11-beta dehydrogenase 1
chr6_+_40628824 2.65 ENSMUST00000071535.6
maltase-glucoamylase
chrX_-_162565514 2.63 ENSMUST00000154424.1
RALBP1 associated Eps domain containing protein 2
chr4_-_134853294 2.61 ENSMUST00000030628.8
transmembrane protein 57
chr17_-_25844417 2.55 ENSMUST00000176591.1
ras homolog gene family, member T2
chr4_+_148140699 2.52 ENSMUST00000140049.1
ENSMUST00000105707.1
MAD2 mitotic arrest deficient-like 2
chr14_-_61556881 2.52 ENSMUST00000022497.8
SPRY domain containing 7
chr1_-_72212249 2.51 ENSMUST00000048860.7
melanoregulin
chr10_-_109010955 2.49 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr16_-_23988852 2.49 ENSMUST00000023151.5
B cell leukemia/lymphoma 6
chr14_-_68533689 2.49 ENSMUST00000022640.7
a disintegrin and metallopeptidase domain 7
chr13_-_71963713 2.48 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr14_+_65969714 2.44 ENSMUST00000153460.1
clusterin
chr13_+_34734837 2.44 ENSMUST00000039605.6
family with sequence similarity 50, member B
chr6_+_3993776 2.42 ENSMUST00000031673.5
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chrM_+_3906 2.38 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr2_-_18048784 2.33 ENSMUST00000142856.1
SKI/DACH domain containing 1
chr18_+_38418946 2.32 ENSMUST00000025293.3
Nedd4 family interacting protein 1
chr18_-_3281752 2.32 ENSMUST00000140332.1
ENSMUST00000147138.1
cAMP responsive element modulator
chr7_+_43690418 2.31 ENSMUST00000056329.6
kallikrein related-peptidase 14
chr1_-_36244245 2.29 ENSMUST00000046875.7
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_126215100 2.28 ENSMUST00000164042.2
predicted gene, 17555
chr2_+_162987330 2.26 ENSMUST00000018012.7
serum/glucocorticoid regulated kinase 2
chr2_+_162987502 2.24 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr7_-_73537621 2.24 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr15_-_58214882 2.22 ENSMUST00000022986.6
F-box protein 32
chr8_+_4349588 2.20 ENSMUST00000110982.1
ENSMUST00000024004.7
chemokine (C-C motif) ligand 25
chr2_-_91195035 2.19 ENSMUST00000111356.1
nuclear receptor subfamily 1, group H, member 3
chr1_+_164503306 2.19 ENSMUST00000181831.1
predicted gene, 26685
chr5_+_146079254 2.18 ENSMUST00000035571.8
cytochrome P450, family 3, subfamily a, polypeptide 59
chr12_+_59129757 2.15 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr13_+_23684192 2.13 ENSMUST00000018246.4
histone cluster 1, H2bc
chr2_-_91195097 2.13 ENSMUST00000002177.2
ENSMUST00000111354.1
nuclear receptor subfamily 1, group H, member 3
chr9_+_43829963 2.12 ENSMUST00000180221.1
predicted gene 3898
chr7_+_103550368 2.11 ENSMUST00000106888.1
olfactory receptor 613
chr6_+_79818031 2.07 ENSMUST00000179797.1
predicted gene, 20594
chr5_-_87538188 2.01 ENSMUST00000031199.4
sulfotransferase family 1B, member 1
chr3_-_28765364 2.00 ENSMUST00000094335.3
predicted pseudogene 6505
chr9_+_45319072 2.00 ENSMUST00000034597.7
transmembrane protease, serine 13
chr8_+_129118043 1.99 ENSMUST00000108744.1
RIKEN cDNA 1700008F21 gene
chr1_+_107361929 1.96 ENSMUST00000027566.2
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr15_+_3270767 1.94 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr12_+_59129720 1.92 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr10_+_59395632 1.88 ENSMUST00000092511.4
predicted pseudogene 10273
chr10_-_68278713 1.86 ENSMUST00000020106.7
AT rich interactive domain 5B (MRF1-like)
chr13_+_4574075 1.85 ENSMUST00000021628.3
aldo-keto reductase family 1, member C21
chr1_-_175625580 1.85 ENSMUST00000027810.7
fumarate hydratase 1
chr19_+_46707443 1.84 ENSMUST00000003655.7
arsenic (+3 oxidation state) methyltransferase
chr11_-_17211504 1.83 ENSMUST00000020317.7
partner of NOB1 homolog (S. cerevisiae)
chrX_+_139563316 1.82 ENSMUST00000113027.1
ring finger protein 128
chr14_-_47189406 1.81 ENSMUST00000089959.6
GTP cyclohydrolase 1
chr2_-_91194767 1.80 ENSMUST00000111355.1
nuclear receptor subfamily 1, group H, member 3
chr7_-_19023538 1.79 ENSMUST00000036018.5
forkhead box A3
chrM_-_14060 1.78 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr4_+_99030946 1.76 ENSMUST00000030280.6
angiopoietin-like 3
chr4_+_41762309 1.74 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr15_-_76232045 1.72 ENSMUST00000167754.1
plectin
chr7_+_127800604 1.70 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_+_185332143 1.69 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
bisphosphate 3'-nucleotidase 1
chr3_+_114904062 1.68 ENSMUST00000081752.6
olfactomedin 3
chr9_-_51328898 1.67 ENSMUST00000039959.4
RIKEN cDNA 1810046K07 gene
chr4_+_152199805 1.66 ENSMUST00000105652.2
acyl-CoA thioesterase 7
chr1_+_175632169 1.65 ENSMUST00000097458.3
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_-_144550777 1.64 ENSMUST00000028915.5
retinoblastoma binding protein 9
chr4_+_89137122 1.63 ENSMUST00000058030.7
methylthioadenosine phosphorylase
chr1_+_175631996 1.62 ENSMUST00000040250.8
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_-_125165707 1.61 ENSMUST00000118875.1
glyceraldehyde-3-phosphate dehydrogenase
chr7_-_141434532 1.59 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr19_+_26623419 1.57 ENSMUST00000176584.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_48559971 1.56 ENSMUST00000169406.1
predicted gene 1818
chr15_-_75431745 1.56 ENSMUST00000096397.1
RIKEN cDNA 9030619P08 gene
chr2_-_38926217 1.55 ENSMUST00000076275.4
ENSMUST00000142130.1
nuclear receptor subfamily 6, group A, member 1
chr10_+_28668560 1.55 ENSMUST00000161345.1
thymocyte selection associated
chr13_-_92131494 1.52 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr1_-_162866502 1.52 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr7_+_5015466 1.51 ENSMUST00000086349.3
zinc finger protein 524
chr18_-_61036189 1.49 ENSMUST00000025521.8
caudal type homeobox 1
chr19_-_5796924 1.49 ENSMUST00000174808.1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr3_+_66985647 1.48 ENSMUST00000162362.1
ENSMUST00000065074.7
arginine/serine-rich coiled-coil 1
chr13_+_119606650 1.47 ENSMUST00000178948.1
predicted gene, 21967
chr11_+_96194299 1.46 ENSMUST00000062709.3
homeobox B13
chr17_-_25844514 1.45 ENSMUST00000176709.1
ras homolog gene family, member T2
chr2_-_89024099 1.44 ENSMUST00000099799.2
olfactory receptor 1217
chr4_-_42661893 1.43 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr10_-_34044302 1.43 ENSMUST00000048052.5
family with sequence similarity 26, member D
chr9_-_21067093 1.43 ENSMUST00000115494.2
zinc finger, GATA-like protein 1
chr3_-_89411781 1.42 ENSMUST00000107429.3
ENSMUST00000129308.2
ENSMUST00000107426.1
ENSMUST00000050398.4
ENSMUST00000162701.1
RFad1, flavin adenine dinucleotide synthetase, homolog (yeast)
chr10_+_24076500 1.41 ENSMUST00000051133.5
trace amine-associated receptor 8A
chr13_-_91388079 1.40 ENSMUST00000181054.1
RIKEN cDNA A830009L08 gene
chr19_-_11081088 1.39 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr8_-_25038875 1.38 ENSMUST00000084031.4
HtrA serine peptidase 4
chr12_-_86726439 1.38 ENSMUST00000021682.8
angel homolog 1 (Drosophila)
chr14_+_55971428 1.37 ENSMUST00000089555.2
chymase 2, mast cell
chr5_-_62766153 1.37 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_40540751 1.36 ENSMUST00000091186.3
inturned planar cell polarity effector homolog (Drosophila)
chr13_+_32802007 1.36 ENSMUST00000021832.6
Werner helicase interacting protein 1
chr11_+_76902152 1.36 ENSMUST00000102495.1
transmembrane and immunoglobulin domain containing 1
chr17_-_35897073 1.35 ENSMUST00000150056.1
ENSMUST00000156817.1
ENSMUST00000146451.1
ENSMUST00000148482.1
RIKEN cDNA 2310061I04 gene
chr12_+_108792946 1.34 ENSMUST00000021692.7
YY1 transcription factor
chr7_+_34912379 1.34 ENSMUST00000075068.7
peptidase D
chr13_+_23934434 1.33 ENSMUST00000072391.1
histone cluster 1, H2aa
chr9_+_107340593 1.33 ENSMUST00000042581.2
RIKEN cDNA 6430571L13 gene
chr15_+_25773985 1.33 ENSMUST00000125667.1
myosin X
chr6_-_24528013 1.33 ENSMUST00000023851.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr13_-_107414742 1.31 ENSMUST00000061241.6
apolipoprotein O, pseudogene
chr3_+_14480692 1.31 ENSMUST00000037321.7
ENSMUST00000120484.1
ENSMUST00000120801.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr7_-_41499890 1.31 ENSMUST00000098509.3
expressed sequence AW146154
chr6_+_129180613 1.30 ENSMUST00000032260.5
C-type lectin domain family 2, member d
chr6_-_125165576 1.30 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_135284075 1.30 ENSMUST00000077340.7
ENSMUST00000074357.7
arginyl aminopeptidase (aminopeptidase B)
chr16_+_29579347 1.29 ENSMUST00000038867.6
ENSMUST00000161186.1
optic atrophy 1
chr12_-_72085393 1.29 ENSMUST00000019862.2
L-3-hydroxyproline dehydratase (trans-)
chr17_+_25829036 1.29 ENSMUST00000026832.7
ENSMUST00000123582.1
jumonji domain containing 8
chr1_+_87594545 1.28 ENSMUST00000165109.1
ENSMUST00000070898.5
neuraminidase 2
chr10_+_116301374 1.27 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr6_-_38354243 1.26 ENSMUST00000114900.1
zinc finger CCCH type, antiviral 1
chr7_+_44198191 1.25 ENSMUST00000085450.2
kallikrein 1-related peptidase b3
chr2_-_140066661 1.25 ENSMUST00000046656.2
ENSMUST00000099304.3
ENSMUST00000110079.2
taspase, threonine aspartase 1
chr16_+_34649920 1.25 ENSMUST00000148562.1
ropporin, rhophilin associated protein 1
chr3_+_106034661 1.25 ENSMUST00000170669.2
predicted gene 4540
chr5_-_93671366 1.24 ENSMUST00000160418.1
ENSMUST00000159578.1
ENSMUST00000162539.1
ENSMUST00000160382.1
ENSMUST00000076321.6
ENSMUST00000101024.3
ENSMUST00000159489.1
ENSMUST00000162964.1
expressed sequence C87414
chr5_-_24842579 1.23 ENSMUST00000030787.8
Ras homolog enriched in brain
chr17_-_35897371 1.23 ENSMUST00000148721.1
RIKEN cDNA 2310061I04 gene
chr19_-_43674844 1.21 ENSMUST00000046038.7
solute carrier family 25, member 28
chr11_+_97029925 1.20 ENSMUST00000021249.4
secernin 2
chr11_+_83473079 1.20 ENSMUST00000021018.4
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr13_+_4434306 1.20 ENSMUST00000021630.8
aldo-keto reductase family 1, member C6
chr2_+_32395896 1.19 ENSMUST00000028162.3
prostaglandin E synthase 2
chr11_+_98446826 1.18 ENSMUST00000019456.4
growth factor receptor bound protein 7
chr7_+_43430088 1.17 ENSMUST00000004732.5
lens intrinsic membrane protein 2
chr2_+_3424123 1.17 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr5_-_121527186 1.16 ENSMUST00000152270.1
MAP kinase-activated protein kinase 5
chr7_-_135528645 1.15 ENSMUST00000053716.7
clarin 3
chr15_+_31224371 1.14 ENSMUST00000044524.9
death-associated protein
chr19_+_12674179 1.14 ENSMUST00000057924.2
olfactory receptor 1442
chr8_-_41054771 1.14 ENSMUST00000093534.4
mitochondrial tumor suppressor 1
chr2_-_63184253 1.13 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr16_-_31314804 1.12 ENSMUST00000115230.1
ENSMUST00000130560.1
apolipoprotein D

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa13

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.5 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
3.6 10.9 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
2.9 31.8 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
2.0 6.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.2 13.6 GO:0070189 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
1.2 3.7 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.2 4.8 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.0 11.0 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.0 2.9 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.8 6.7 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7 2.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7 2.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.7 4.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.6 2.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6 2.5 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.6 1.8 GO:0006106 fumarate metabolic process(GO:0006106)
0.6 6.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.6 2.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.5 2.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.5 10.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.5 2.9 GO:0006083 acetate metabolic process(GO:0006083)
0.5 7.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.5 1.4 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.5 8.7 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.5 1.8 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.4 1.3 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.4 1.8 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.4 3.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 1.7 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4 1.6 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.4 2.4 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4 1.1 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 9.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.4 1.1 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.4 5.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.4 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.4 1.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 3.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 2.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 0.7 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.3 0.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 1.5 GO:0035063 nuclear speck organization(GO:0035063)
0.3 0.9 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.3 4.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 0.8 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.3 2.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 1.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 4.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 1.0 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2 0.7 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 1.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 2.4 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.9 GO:0002188 translation reinitiation(GO:0002188)
0.2 2.5 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.9 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.3 GO:0014042 positive regulation of mitochondrial fusion(GO:0010636) positive regulation of neuron maturation(GO:0014042)
0.2 1.9 GO:0060613 fat pad development(GO:0060613)
0.2 0.6 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.6 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.2 1.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 4.0 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2 3.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.8 GO:0060296 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 1.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 1.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.2 1.1 GO:0015867 ATP transport(GO:0015867)
0.2 0.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 1.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.2 2.3 GO:0007320 insemination(GO:0007320)
0.2 1.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 1.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 3.4 GO:0009404 toxin metabolic process(GO:0009404)
0.2 2.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 1.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.3 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.2 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.6 GO:0061043 positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
0.1 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 2.6 GO:0043383 negative T cell selection(GO:0043383)
0.1 1.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 1.0 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 0.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 3.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.4 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.1 1.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 4.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 6.5 GO:0006953 acute-phase response(GO:0006953)
0.1 1.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 1.1 GO:0001842 neural fold formation(GO:0001842)
0.1 0.7 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 2.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 2.6 GO:0042640 anagen(GO:0042640)
0.1 3.1 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.8 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 1.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.3 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.7 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 2.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 0.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.7 GO:0046697 decidualization(GO:0046697)
0.1 0.3 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 1.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.7 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 1.8 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 2.2 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.9 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.4 GO:0033151 V(D)J recombination(GO:0033151)
0.1 1.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 2.4 GO:0007602 phototransduction(GO:0007602)
0.1 1.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 2.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 1.2 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 1.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.2 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.8 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.6 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 0.3 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.5 GO:0060068 vagina development(GO:0060068)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 1.1 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 1.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 2.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.5 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 2.1 GO:0046677 response to antibiotic(GO:0046677)
0.1 2.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.8 GO:0051451 myoblast migration(GO:0051451)
0.0 1.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 2.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.6 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.5 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 1.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 1.4 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 1.4 GO:0048599 oocyte development(GO:0048599)
0.0 0.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.4 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 3.3 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.0 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.9 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.4 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 5.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 1.5 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 1.0 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.4 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.0 3.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.7 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.0 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.8 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.4 5.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
1.4 4.2 GO:0046691 intracellular canaliculus(GO:0046691)
0.8 6.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.8 0.8 GO:0071920 cleavage body(GO:0071920)
0.4 1.8 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.4 2.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 2.9 GO:0097452 GAIT complex(GO:0097452)
0.3 1.0 GO:0000814 ESCRT II complex(GO:0000814)
0.3 6.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 1.1 GO:0090537 CERF complex(GO:0090537)
0.2 1.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 0.7 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 0.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.2 2.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.2 3.5 GO:0031045 dense core granule(GO:0031045)
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 4.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 4.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 11.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 9.4 GO:0000502 proteasome complex(GO:0000502)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.3 GO:0031011 Ino80 complex(GO:0031011)
0.1 8.8 GO:0070469 respiratory chain(GO:0070469)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.1 2.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 3.3 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 2.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0000801 central element(GO:0000801)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 2.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 15.4 GO:0043235 receptor complex(GO:0043235)
0.0 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 6.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 3.3 GO:0043204 perikaryon(GO:0043204)
0.0 8.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 3.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.6 GO:0005770 late endosome(GO:0005770)
0.0 3.0 GO:0044306 neuron projection terminus(GO:0044306)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 27.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.3 GO:0005009 insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186)
3.4 10.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
2.8 11.0 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
1.7 8.3 GO:0008502 melatonin receptor activity(GO:0008502)
1.5 5.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.5 10.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.2 6.1 GO:0032810 sterol response element binding(GO:0032810)
1.0 2.9 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.0 2.9 GO:0019807 aspartoacylase activity(GO:0019807)
0.9 2.8 GO:0031403 lithium ion binding(GO:0031403)
0.9 2.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.8 3.1 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.7 4.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 3.3 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.6 2.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.6 1.9 GO:0070401 NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.6 14.2 GO:0005550 pheromone binding(GO:0005550)
0.6 2.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.5 3.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 1.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 2.7 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.5 3.7 GO:0005113 patched binding(GO:0005113)
0.4 1.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.4 1.3 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.4 1.7 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 2.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.4 1.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 1.1 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 1.8 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 1.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 4.2 GO:0015250 water channel activity(GO:0015250)
0.3 7.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.3 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 0.8 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.3 1.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.2 1.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 0.7 GO:0004794 L-serine ammonia-lyase activity(GO:0003941) L-threonine ammonia-lyase activity(GO:0004794)
0.2 0.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 6.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 3.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 2.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 2.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 0.7 GO:0030977 taurine binding(GO:0030977)
0.2 0.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.6 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 0.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 5.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 1.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.2 1.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.8 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.2 2.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 4.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 0.7 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 0.4 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.2 2.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.3 GO:0050897 cobalt ion binding(GO:0050897)
0.2 1.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 2.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 6.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 2.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 1.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.8 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 4.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 4.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.9 GO:0032564 dATP binding(GO:0032564)
0.1 2.5 GO:0008432 JUN kinase binding(GO:0008432)
0.1 4.2 GO:0030332 cyclin binding(GO:0030332)
0.1 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 10.4 GO:0005496 steroid binding(GO:0005496)
0.1 0.7 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 9.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.0 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.1 0.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 2.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 11.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.2 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 7.1 GO:0005179 hormone activity(GO:0005179)
0.1 2.8 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0016918 retinal binding(GO:0016918)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 1.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.4 GO:0030507 spectrin binding(GO:0030507)
0.0 1.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 3.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 1.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.5 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.6 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 6.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 6.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 4.9 PID FOXO PATHWAY FoxO family signaling
0.1 4.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 5.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.9 2.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.8 13.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.5 2.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 4.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 3.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 7.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 2.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 5.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 4.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 1.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 5.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 6.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 8.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 3.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.5 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 1.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 5.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism