Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Hoxa7_Hoxc8

Z-value: 0.43

Motif logo

logo of logo of

Transcription factors associated with Hoxa7_Hoxc8

Gene Symbol Gene ID Gene Info
Hoxa7
ENSMUSG00000038236.6 homeobox A7
Hoxc8
ENSMUSG00000001657.6 homeobox C8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxc8mm10_v2_chr15_+_102990576_102990622-0.212.2e-01Click!
Hoxa7mm10_v2_chr6_-_52218686_52218716-0.202.4e-01Click!

Activity profile of Hoxa7_Hoxc8 motif

Sorted Z-values of Hoxa7_Hoxc8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_80000292 1.09 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr6_+_30541582 1.04 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr3_-_75270073 0.62 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr2_+_69897255 0.43 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr9_-_90255927 0.39 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr14_-_100149764 0.32 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr15_+_25773985 0.32 ENSMUST00000125667.1
Myo10
myosin X
chr4_+_108719649 0.32 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr12_-_55014329 0.30 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr3_+_5218516 0.30 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr3_-_81924463 0.29 ENSMUST00000069880.2
Gm9989
predicted gene 9989
chr3_+_103832562 0.26 ENSMUST00000062945.5
Bcl2l15
BCLl2-like 15
chr15_+_98571004 0.25 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr17_+_23853519 0.24 ENSMUST00000061725.7
Prss32
protease, serine, 32
chr4_+_34893772 0.24 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
Cga
glycoprotein hormones, alpha subunit
chr12_-_40248073 0.23 ENSMUST00000169926.1
Ifrd1
interferon-related developmental regulator 1
chr2_+_69219971 0.23 ENSMUST00000005364.5
ENSMUST00000112317.2
G6pc2
glucose-6-phosphatase, catalytic, 2
chr5_-_62766153 0.23 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_94152607 0.23 ENSMUST00000034211.8
Mt3
metallothionein 3
chr4_-_82850721 0.22 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr2_-_121235689 0.22 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr15_-_75905349 0.21 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr5_-_62765618 0.21 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr13_-_102905740 0.20 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr10_-_45470201 0.19 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr14_+_27000362 0.19 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr13_-_102906046 0.19 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr19_-_50678642 0.19 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1
VPS10 domain receptor protein SORCS 1
chr11_-_99374895 0.18 ENSMUST00000006963.2
Krt28
keratin 28
chr13_+_23575753 0.18 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr1_+_72284367 0.17 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169
transmembrane protein 169
chr1_-_134955847 0.16 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr10_+_37139558 0.16 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr15_-_100425050 0.15 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_-_59220150 0.15 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr1_-_126738167 0.15 ENSMUST00000160693.1
Nckap5
NCK-associated protein 5
chr7_+_45621805 0.14 ENSMUST00000033100.4
Izumo1
izumo sperm-egg fusion 1
chr14_-_36919314 0.14 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr15_-_37458523 0.14 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr4_+_145585166 0.14 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212
predicted gene 13212
chr15_+_81744848 0.13 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chrX_+_159303266 0.13 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr8_+_45885479 0.13 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr4_+_102589687 0.13 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b
phosphodiesterase 4B, cAMP specific
chrX_+_114474569 0.13 ENSMUST00000133447.1
Klhl4
kelch-like 4
chr15_-_8710734 0.12 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_55919605 0.12 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr6_-_118479237 0.12 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr3_+_5218589 0.12 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr11_+_31832660 0.12 ENSMUST00000132857.1
Gm12107
predicted gene 12107
chr3_+_121291725 0.12 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr9_+_119063429 0.11 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill
villin-like
chr2_-_45117349 0.11 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr17_+_34039437 0.11 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2
collagen, type XI, alpha 2
chr10_-_20724696 0.11 ENSMUST00000170265.1
Pde7b
phosphodiesterase 7B
chr6_-_130193112 0.11 ENSMUST00000112032.1
ENSMUST00000071554.2
Klra9
killer cell lectin-like receptor subfamily A, member 9
chr3_+_59952185 0.10 ENSMUST00000094227.3
Gm9696
predicted gene 9696
chr9_+_72806874 0.09 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr9_+_113812547 0.09 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2
CLIP associating protein 2
chr13_-_55021196 0.09 ENSMUST00000153665.1
Hk3
hexokinase 3
chr3_+_96645579 0.09 ENSMUST00000119365.1
ENSMUST00000029744.5
Itga10
integrin, alpha 10
chr2_+_110721340 0.09 ENSMUST00000111016.2
Muc15
mucin 15
chr19_-_53944621 0.09 ENSMUST00000135402.2
Bbip1
BBSome interacting protein 1
chr1_-_132367879 0.09 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr10_-_76110956 0.08 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr11_+_29373618 0.08 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a
coiled coil domain containing 88A
chr3_-_86548268 0.08 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr2_-_116067391 0.08 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr10_-_117148474 0.08 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr2_-_164171113 0.08 ENSMUST00000045196.3
Kcns1
K+ voltage-gated channel, subfamily S, 1
chr3_+_55782500 0.08 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr19_-_32196393 0.08 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr18_+_53551594 0.07 ENSMUST00000115398.1
Prdm6
PR domain containing 6
chr2_+_36230426 0.07 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr16_-_75909272 0.07 ENSMUST00000114239.2
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr6_+_37870786 0.07 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24
tripartite motif-containing 24
chr18_+_4920509 0.07 ENSMUST00000126977.1
Svil
supervillin
chr7_+_30493622 0.07 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
Prodh2
proline dehydrogenase (oxidase) 2
chr7_+_126950687 0.07 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr19_-_55241236 0.06 ENSMUST00000069183.6
Gucy2g
guanylate cyclase 2g
chr18_+_37518341 0.06 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr14_+_54431597 0.06 ENSMUST00000089688.4
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
chr16_-_50330987 0.06 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr17_-_45659312 0.06 ENSMUST00000120717.1
Capn11
calpain 11
chr10_-_86011833 0.06 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc
BPI fold containing family C
chr10_+_76147451 0.06 ENSMUST00000020450.3
Slc5a4a
solute carrier family 5, member 4a
chr3_+_5214763 0.06 ENSMUST00000177924.1
Gm10748
predicted gene 10748
chr9_-_79977782 0.06 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr6_-_30693676 0.06 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41
centrosomal protein 41
chr4_-_115133977 0.06 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr3_-_17230976 0.05 ENSMUST00000177874.1
Gm5283
predicted gene 5283
chr2_-_79456750 0.05 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chrM_+_9870 0.05 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr8_-_24725762 0.05 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
Adam3
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr18_-_56975333 0.05 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik
RIKEN cDNA C330018D20 gene
chr12_+_98746935 0.05 ENSMUST00000110105.2
ENSMUST00000110104.2
ENSMUST00000057000.9
Zc3h14
zinc finger CCCH type containing 14
chr7_-_46667303 0.05 ENSMUST00000168335.1
Tph1
tryptophan hydroxylase 1
chr5_+_66968559 0.04 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr5_+_138187485 0.04 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr2_-_177267036 0.04 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr16_-_45724600 0.04 ENSMUST00000096057.4
Tagln3
transgelin 3
chr2_+_23069210 0.04 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr1_-_24612700 0.04 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr12_+_71170589 0.04 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr10_+_41303968 0.04 ENSMUST00000173517.2
Ak9
adenylate kinase 9
chr18_+_23753708 0.04 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr1_-_172027269 0.03 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr2_+_83724397 0.03 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav
integrin alpha V
chr13_-_81710937 0.03 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g
polymerase (RNA) III (DNA directed) polypeptide G
chr3_+_5218546 0.03 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr19_+_5474681 0.03 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr15_-_8710409 0.03 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_104202609 0.03 ENSMUST00000066708.5
Dmp1
dentin matrix protein 1
chr16_+_45224315 0.03 ENSMUST00000102802.3
ENSMUST00000063654.4
Btla
B and T lymphocyte associated
chr1_-_150164943 0.03 ENSMUST00000181308.1
Gm26687
predicted gene, 26687
chr1_-_134955908 0.02 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chrX_-_101086020 0.02 ENSMUST00000113710.1
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr3_+_55461758 0.02 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr6_-_137169710 0.02 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr19_-_41933276 0.02 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1
exosome component 1
chr2_+_127854628 0.02 ENSMUST00000028859.1
Acoxl
acyl-Coenzyme A oxidase-like
chrX_+_166170449 0.01 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
Gemin8
gem (nuclear organelle) associated protein 8
chr11_-_73326472 0.01 ENSMUST00000155630.2
Aspa
aspartoacylase
chr11_-_65269941 0.01 ENSMUST00000102635.3
Myocd
myocardin
chr9_+_38877126 0.01 ENSMUST00000078289.2
Olfr926
olfactory receptor 926
chr15_-_67113909 0.01 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr4_-_136602641 0.01 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a
lysine (K)-specific demethylase 1A
chr17_+_88440711 0.01 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2
forkhead box N2
chr8_+_23411490 0.01 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr1_+_82316452 0.00 ENSMUST00000027322.7
Rhbdd1
rhomboid domain containing 1
chr18_+_55057557 0.00 ENSMUST00000181765.1
Gm4221
predicted gene 4221

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa7_Hoxc8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.0 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 1.1 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.0 GO:0034684 integrin alphav-beta5 complex(GO:0034684) integrin alphav-beta6 complex(GO:0034685)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors