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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxb2_Dlx2

Z-value: 0.98

Motif logo

Transcription factors associated with Hoxb2_Dlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000075588.5 homeobox B2
ENSMUSG00000023391.7 distal-less homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dlx2mm10_v2_chr2_-_71546745_71546758-0.616.6e-05Click!
Hoxb2mm10_v2_chr11_+_96351632_96351632-0.609.6e-05Click!

Activity profile of Hoxb2_Dlx2 motif

Sorted Z-values of Hoxb2_Dlx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_60081861 7.01 ENSMUST00000029326.5
succinate receptor 1
chr13_+_4434306 5.07 ENSMUST00000021630.8
aldo-keto reductase family 1, member C6
chr19_-_7966000 4.53 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr6_-_138079916 4.34 ENSMUST00000171804.1
solute carrier family 15, member 5
chr3_+_62419668 4.27 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr10_+_127898515 3.52 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr10_-_92375367 3.43 ENSMUST00000182870.1
predicted gene, 20757
chr2_+_68104671 3.37 ENSMUST00000042456.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_-_60921270 3.12 ENSMUST00000096418.3
alpha-1-B glycoprotein
chrX_-_143933089 2.94 ENSMUST00000087313.3
doublecortin
chr14_+_33941021 2.91 ENSMUST00000100720.1
growth differentiation factor 2
chr10_-_24101951 2.90 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr16_+_42907563 2.85 ENSMUST00000151244.1
ENSMUST00000114694.2
zinc finger and BTB domain containing 20
chr1_-_72284248 2.54 ENSMUST00000097698.4
ENSMUST00000027381.6
peroxisomal trans-2-enoyl-CoA reductase
chr9_-_71163224 2.42 ENSMUST00000074465.2
aquaporin 9
chrM_+_10167 2.36 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr1_-_140183283 2.33 ENSMUST00000111977.1
complement component factor h
chr1_-_139608282 2.32 ENSMUST00000170441.2
complement factor H-related 3
chr1_-_140183404 2.29 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr5_-_87569023 2.29 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr10_-_107486077 2.25 ENSMUST00000000445.1
myogenic factor 5
chr14_-_118052235 2.22 ENSMUST00000022725.2
dopachrome tautomerase
chr2_+_116067213 2.15 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr5_+_90561102 2.15 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr2_+_70474923 2.09 ENSMUST00000100043.2
trans-acting transcription factor 5
chr7_+_103550368 2.02 ENSMUST00000106888.1
olfactory receptor 613
chr16_+_22918378 2.00 ENSMUST00000170805.1
fetuin beta
chrM_+_9870 1.94 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chrM_+_7005 1.89 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr3_+_138374121 1.88 ENSMUST00000171054.1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr5_+_139543889 1.80 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr7_-_48848023 1.80 ENSMUST00000032658.6
cysteine and glycine-rich protein 3
chr3_+_138313279 1.77 ENSMUST00000013455.6
ENSMUST00000106247.1
alcohol dehydrogenase 6A (class V)
chr7_-_100656953 1.70 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr1_-_24612700 1.67 ENSMUST00000088336.1
predicted gene 10222
chr3_+_122419772 1.59 ENSMUST00000029766.4
breast cancer anti-estrogen resistance 3
chr5_-_87482258 1.56 ENSMUST00000079811.6
ENSMUST00000144144.1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr10_+_39612934 1.56 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr2_+_69897220 1.55 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr11_-_99521258 1.54 ENSMUST00000076948.1
keratin 39
chr14_-_68533689 1.53 ENSMUST00000022640.7
a disintegrin and metallopeptidase domain 7
chr5_+_42067960 1.49 ENSMUST00000087332.4
predicted gene 16223
chr8_-_5105232 1.49 ENSMUST00000023835.1
solute carrier family 10, member 2
chr4_+_108719649 1.47 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr17_-_34882094 1.47 ENSMUST00000025230.8
complement component 2 (within H-2S)
chr18_-_75697639 1.46 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chr1_+_88200601 1.45 ENSMUST00000049289.8
UDP glucuronosyltransferase 1 family, polypeptide A2
chr11_-_113710017 1.44 ENSMUST00000018871.1
cleavage and polyadenylation specific factor 4-like
chr15_-_101892916 1.42 ENSMUST00000100179.1
keratin 76
chr3_+_133338936 1.40 ENSMUST00000150386.1
ENSMUST00000125858.1
pyrophosphatase (inorganic) 2
chr6_-_115592571 1.39 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr11_-_99521336 1.38 ENSMUST00000107445.1
keratin 39
chr17_-_83846769 1.37 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr11_-_43901187 1.36 ENSMUST00000067258.2
ENSMUST00000139906.1
adrenergic receptor, alpha 1b
chr5_-_62766153 1.34 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_-_37458523 1.33 ENSMUST00000116445.2
neurocalcin delta
chr6_+_124304646 1.30 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr11_-_99374895 1.27 ENSMUST00000006963.2
keratin 28
chr19_-_39649046 1.26 ENSMUST00000067328.6
cytochrome P450, family 2, subfamily c, polypeptide 67
chr9_-_71168657 1.26 ENSMUST00000113570.1
aquaporin 9
chrX_-_60893430 1.26 ENSMUST00000135107.2
SRY-box containing gene 3
chr8_+_45658666 1.26 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr16_+_43235856 1.25 ENSMUST00000146708.1
zinc finger and BTB domain containing 20
chr9_+_43829963 1.24 ENSMUST00000180221.1
predicted gene 3898
chrX_-_143933204 1.24 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr4_-_104876383 1.23 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
complement component 8, alpha polypeptide
chr5_-_86373413 1.21 ENSMUST00000031175.5
transmembrane protease, serine 11d
chr2_-_5676046 1.19 ENSMUST00000114987.3
calcium/calmodulin-dependent protein kinase ID
chr2_-_166155624 1.19 ENSMUST00000109249.2
sulfatase 2
chr2_+_109917639 1.19 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr14_+_52824340 1.17 ENSMUST00000103648.2
T cell receptor alpha variable 11D
chr9_+_32116040 1.15 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr18_-_38866702 1.14 ENSMUST00000115582.1
fibroblast growth factor 1
chr12_-_57546121 1.13 ENSMUST00000044380.6
forkhead box A1
chr7_-_34654342 1.13 ENSMUST00000108069.1
potassium channel tetramerisation domain containing 15
chrM_+_9452 1.13 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr6_+_8948608 1.11 ENSMUST00000160300.1
neurexophilin 1
chr13_+_89540636 1.09 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr1_+_74284930 1.08 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia
chr12_-_56613270 1.07 ENSMUST00000072631.5
NK2 homeobox 9
chr2_-_166155272 1.07 ENSMUST00000088086.3
sulfatase 2
chr3_-_157925056 1.06 ENSMUST00000118539.1
cystathionase (cystathionine gamma-lyase)
chr2_-_37359274 1.05 ENSMUST00000009174.8
phosducin-like
chr15_-_67113909 1.03 ENSMUST00000092640.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr12_-_48559971 1.03 ENSMUST00000169406.1
predicted gene 1818
chr7_+_5015466 1.03 ENSMUST00000086349.3
zinc finger protein 524
chr9_-_15301555 1.03 ENSMUST00000034414.8
RIKEN cDNA 4931406C07 gene
chr11_+_99873389 1.03 ENSMUST00000093936.3
keratin associated protein 9-1
chr13_+_23807027 1.02 ENSMUST00000006786.4
ENSMUST00000099697.2
solute carrier family 17 (sodium phosphate), member 2
chr8_-_84846860 1.01 ENSMUST00000003912.6
calreticulin
chr19_+_26749726 0.98 ENSMUST00000175842.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_87925624 0.97 ENSMUST00000113271.2
casein kappa
chr2_+_23069210 0.96 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr18_-_3281036 0.96 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr19_-_42202150 0.95 ENSMUST00000018966.7
secreted frizzled-related sequence protein 5
chr11_-_119547744 0.94 ENSMUST00000026670.4
neuronal pentraxin 1
chr3_-_19264959 0.94 ENSMUST00000121951.1
phosphodiesterase 7A
chr9_+_121950988 0.94 ENSMUST00000043011.7
family with sequence similarity 198, member A
chr4_+_97777780 0.94 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
nuclear factor I/A
chr18_+_56432116 0.91 ENSMUST00000070166.5
GRAM domain containing 3
chr2_-_77703252 0.91 ENSMUST00000171063.1
zinc finger protein 385B
chr1_+_132298606 0.91 ENSMUST00000046071.4
kelch domain containing 8A
chr16_+_37580137 0.90 ENSMUST00000160847.1
homogentisate 1, 2-dioxygenase
chr17_-_90088343 0.90 ENSMUST00000173917.1
neurexin I
chr6_-_125380793 0.90 ENSMUST00000042647.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chrX_-_100594860 0.89 ENSMUST00000053373.1
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr4_+_136143497 0.88 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr17_+_45734506 0.87 ENSMUST00000180558.1
RIKEN cDNA F630040K05 gene
chrX_+_57212110 0.84 ENSMUST00000033466.1
CD40 ligand
chr13_-_53473074 0.83 ENSMUST00000021922.8
msh homeobox 2
chr2_+_132847719 0.83 ENSMUST00000124836.1
ENSMUST00000154160.1
cardiolipin synthase 1
chr6_+_37870786 0.83 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr10_+_53337686 0.83 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chr12_-_104473236 0.82 ENSMUST00000021513.4
goosecoid homeobox
chr3_+_94398517 0.81 ENSMUST00000050975.3
leucine rich repeat and Ig domain containing 4
chr14_+_55559993 0.81 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr4_-_14621669 0.80 ENSMUST00000143105.1
solute carrier family 26, member 7
chr5_-_62765618 0.80 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_55560010 0.79 ENSMUST00000147981.1
ENSMUST00000133256.1
DDB1 and CUL4 associated factor 11
chr6_-_136171722 0.78 ENSMUST00000053880.6
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_-_71750083 0.78 ENSMUST00000180494.1
predicted gene, 17250
chr6_-_98342728 0.78 ENSMUST00000164491.1
predicted gene 765
chr2_+_20737306 0.78 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr18_+_9707639 0.78 ENSMUST00000040069.8
collectin sub-family member 12
chr2_+_69897255 0.76 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr9_-_16378231 0.75 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr11_+_99879187 0.74 ENSMUST00000078442.3
predicted gene 11567
chr1_-_163725123 0.74 ENSMUST00000159679.1
methyltransferase like 11B
chr11_+_73350839 0.73 ENSMUST00000120137.1
olfactory receptor 20
chr6_-_130231638 0.73 ENSMUST00000088011.4
ENSMUST00000112013.1
ENSMUST00000049304.7
killer cell lectin-like receptor, subfamily A, member 7
chr17_+_36958571 0.73 ENSMUST00000040177.6
Znrd1 antisense
chr8_+_45658731 0.73 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr15_+_31224371 0.73 ENSMUST00000044524.9
death-associated protein
chr17_+_3397189 0.72 ENSMUST00000072156.6
T cell lymphoma invasion and metastasis 2
chr17_+_36958623 0.71 ENSMUST00000173814.1
Znrd1 antisense
chr5_+_90518932 0.71 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr4_-_42661893 0.70 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr11_-_49114874 0.70 ENSMUST00000109201.1
olfactory receptor 1396
chrX_+_134187492 0.70 ENSMUST00000064476.4
ADP-ribosylation factor-like 13A
chr1_-_190170671 0.69 ENSMUST00000175916.1
prospero-related homeobox 1
chr16_-_48771956 0.69 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr3_+_86070915 0.69 ENSMUST00000182666.1
SH3 domain protein D19
chr7_+_64501687 0.69 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chrX_+_139563316 0.69 ENSMUST00000113027.1
ring finger protein 128
chr5_+_89028035 0.68 ENSMUST00000113216.2
ENSMUST00000134303.1
solute carrier family 4 (anion exchanger), member 4
chr3_-_92123943 0.68 ENSMUST00000070284.3
proline rich 9
chr14_-_48665098 0.68 ENSMUST00000118578.1
orthodenticle homolog 2 (Drosophila)
chrM_+_7759 0.67 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrM_+_8600 0.66 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr5_-_84417359 0.66 ENSMUST00000113401.1
Eph receptor A5
chr11_-_96075581 0.65 ENSMUST00000107686.1
ENSMUST00000107684.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr9_+_54980880 0.65 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_-_119895446 0.65 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr13_+_93674403 0.65 ENSMUST00000048001.6
dimethylglycine dehydrogenase precursor
chr6_-_147264124 0.64 ENSMUST00000052296.6
parathyroid hormone-like peptide
chr11_-_99337930 0.63 ENSMUST00000100482.2
keratin 26
chr11_-_31671863 0.63 ENSMUST00000058060.7
biorientation of chromosomes in cell division 1
chr7_-_90475971 0.62 ENSMUST00000032843.7
transmembrane protein 126B
chr7_-_126584220 0.62 ENSMUST00000128970.1
ENSMUST00000116269.2
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr4_-_83285141 0.61 ENSMUST00000150522.1
tetratricopeptide repeat domain 39B
chr1_+_107422681 0.60 ENSMUST00000112710.1
ENSMUST00000086690.4
serine (or cysteine) peptidase inhibitor, clade B, member 7
chr11_+_114851507 0.60 ENSMUST00000177952.1
G protein-coupled receptor, family C, group 5, member C
chr11_+_114851142 0.60 ENSMUST00000133245.1
ENSMUST00000122967.2
G protein-coupled receptor, family C, group 5, member C
chr12_+_111814170 0.60 ENSMUST00000021714.7
zinc finger, FYVE domain containing 21
chr11_-_100088226 0.60 ENSMUST00000107419.1
keratin 32
chr2_+_125136692 0.58 ENSMUST00000099452.2
cortexin 2
chr17_-_70853482 0.58 ENSMUST00000118283.1
TGFB-induced factor homeobox 1
chr5_+_89027959 0.58 ENSMUST00000130041.1
solute carrier family 4 (anion exchanger), member 4
chr11_-_96075655 0.57 ENSMUST00000090541.5
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr4_-_14621494 0.57 ENSMUST00000149633.1
solute carrier family 26, member 7
chr6_+_63255971 0.55 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr5_-_137531204 0.55 ENSMUST00000150063.2
guanine nucleotide binding protein (G protein), beta 2
chr11_+_23306884 0.54 ENSMUST00000180046.1
ubiquitin specific peptidase 34
chr7_-_102116705 0.54 ENSMUST00000084830.1
cholinergic receptor, nicotinic, alpha polypeptide 10
chr1_-_9298499 0.53 ENSMUST00000132064.1
syntrophin, gamma 1
chr3_-_32491969 0.53 ENSMUST00000164954.1
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chr1_+_104768510 0.52 ENSMUST00000062528.8
cadherin 20
chr6_-_126645784 0.52 ENSMUST00000055168.3
potassium voltage-gated channel, shaker-related subfamily, member 1
chr5_-_137645695 0.51 ENSMUST00000057314.3
insulin receptor substrate 3
chr8_+_22624019 0.50 ENSMUST00000033936.6
dickkopf homolog 4 (Xenopus laevis)
chr9_-_106891401 0.50 ENSMUST00000069036.7
mesencephalic astrocyte-derived neurotrophic factor
chr16_-_93929512 0.50 ENSMUST00000177648.1
claudin 14
chr4_+_43401232 0.49 ENSMUST00000125399.1
RUN and SH3 domain containing 2
chr4_-_155056784 0.49 ENSMUST00000131173.2
phospholipase C, eta 2
chr16_+_45094036 0.48 ENSMUST00000061050.5
coiled-coil domain containing 80
chr1_-_190170178 0.48 ENSMUST00000177288.1
prospero-related homeobox 1
chr8_-_3625274 0.48 ENSMUST00000004749.6
Purkinje cell protein 2 (L7)
chr8_-_84662841 0.47 ENSMUST00000060427.4
immediate early response 2
chr3_-_88461182 0.47 ENSMUST00000166237.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_67974567 0.47 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr11_+_94327984 0.47 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr5_-_66054499 0.47 ENSMUST00000145625.1
RNA binding motif protein 47
chr11_-_82890541 0.47 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
RAD51 homolog D
chr8_-_61902669 0.46 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr11_-_100762928 0.46 ENSMUST00000107360.2
ENSMUST00000055083.3
hypocretin
chr7_+_64501949 0.46 ENSMUST00000138829.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr9_-_103222063 0.46 ENSMUST00000170904.1
transferrin
chr7_-_73541738 0.45 ENSMUST00000169922.2
chromodomain helicase DNA binding protein 2
chr18_+_36281069 0.45 ENSMUST00000051301.3
purine rich element binding protein A
chr7_+_64502090 0.45 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.9 3.7 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.8 2.4 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.6 1.8 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.6 2.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 4.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 2.3 GO:0000103 sulfate assimilation(GO:0000103)
0.5 1.4 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.5 1.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 0.4 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.4 1.2 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.4 1.2 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 1.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.4 3.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 1.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.4 1.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.3 4.5 GO:0015747 urate transport(GO:0015747)
0.3 1.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 2.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 0.8 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.3 0.8 GO:0051795 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.2 4.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 0.9 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 0.6 GO:0060618 nipple development(GO:0060618)
0.2 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 1.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 0.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 0.9 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.5 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.2 3.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 4.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 1.4 GO:0046874 quinolinate metabolic process(GO:0046874)
0.2 1.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 2.5 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.5 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.2 0.9 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.2 0.9 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) diencephalon morphogenesis(GO:0048852)
0.2 1.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 1.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.4 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.4 GO:2000863 positive regulation of estrogen secretion(GO:2000863)
0.1 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.7 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 1.0 GO:0030242 pexophagy(GO:0030242)
0.1 3.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.5 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.8 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.8 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 1.4 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.3 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.3 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.8 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 4.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.5 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 2.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 2.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.2 GO:1902868 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.5 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.0 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:1904936 forebrain anterior/posterior pattern specification(GO:0021797) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 1.3 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.1 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.1 0.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.6 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) excitatory synapse assembly(GO:1904861)
0.0 0.3 GO:0042364 cobalamin metabolic process(GO:0009235) water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 2.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:2000292 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.7 GO:0010225 response to UV-C(GO:0010225)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 1.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.9 GO:0030903 notochord development(GO:0030903)
0.0 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 1.1 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.9 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 1.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.4 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 1.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0 0.7 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:1903671 cytoplasm organization(GO:0007028) negative regulation of sprouting angiogenesis(GO:1903671)
0.0 0.5 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.1 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.1 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 1.3 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.2 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.5 GO:0007595 lactation(GO:0007595)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0071953 elastic fiber(GO:0071953)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 6.6 GO:0070469 respiratory chain(GO:0070469)
0.1 1.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.7 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 9.2 GO:0072562 blood microparticle(GO:0072562)
0.1 6.3 GO:0005882 intermediate filament(GO:0005882)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 2.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 3.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 6.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0070695 HOPS complex(GO:0030897) FHF complex(GO:0070695)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.5 GO:0000502 proteasome complex(GO:0000502)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.3 GO:0030426 growth cone(GO:0030426)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.8 2.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.8 3.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.7 3.7 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.7 4.6 GO:0001851 complement component C3b binding(GO:0001851)
0.5 2.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.4 1.2 GO:0005118 sevenless binding(GO:0005118)
0.4 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 3.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 4.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 1.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 1.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.7 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.6 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 5.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 3.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.7 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 1.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.8 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.1 GO:0001846 opsonin binding(GO:0001846)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 2.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 3.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.3 GO:0051381 histamine binding(GO:0051381)
0.1 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.2 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 3.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 2.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 2.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0005025 transforming growth factor beta-activated receptor activity(GO:0005024) transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 3.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.1 PID FGF PATHWAY FGF signaling pathway
0.0 2.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 3.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 3.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression