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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for Hsfy2
Z-value: 1.28
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Transcription factors associated with Hsfy2
Network of associatons between targets according to the STRING database.
First level regulatory network of Hsfy2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 15.4 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.1 | 8.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 4.9 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.4 | 4.6 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.1 | 4.3 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
| 0.1 | 4.2 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.2 | 4.0 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 1.1 | 3.3 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 0.6 | 3.2 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.0 | 3.2 | GO:0043588 | skin development(GO:0043588) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 17.9 | GO:0005818 | aster(GO:0005818) |
| 0.1 | 5.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.2 | 4.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.9 | 3.5 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 3.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.2 | 3.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.8 | 3.2 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 3.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.0 | 2.9 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.3 | 2.8 | GO:0097165 | nuclear stress granule(GO:0097165) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 12.7 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.1 | 8.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 4.7 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.8 | 4.6 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.1 | 4.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.8 | 4.2 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.1 | 3.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 3.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 3.3 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.2 | 3.0 | GO:0008097 | 5S rRNA binding(GO:0008097) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.7 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 5.4 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 3.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 2.8 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 2.8 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 2.0 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.2 | 1.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.8 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.4 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 4.2 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 4.0 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 3.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 3.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 3.0 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.2 | 2.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 2.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 2.5 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 2.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |