Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Klf15

Z-value: 1.30

Motif logo

logo of

Transcription factors associated with Klf15

Gene Symbol Gene ID Gene Info
Klf15
ENSMUSG00000030087.5 Kruppel-like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90462562_904625870.651.9e-05Click!

Activity profile of Klf15 motif

Sorted Z-values of Klf15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_148045891 5.11 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr5_+_130448801 3.91 ENSMUST00000111288.2
Caln1
calneuron 1
chr18_-_38211957 3.45 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1
protocadherin 1
chr11_+_98348404 3.23 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_99626936 3.08 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chr4_+_97777780 2.98 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia
nuclear factor I/A
chr2_-_25501717 2.91 ENSMUST00000015227.3
C8g
complement component 8, gamma polypeptide
chr8_-_41133697 2.89 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
Mtus1
mitochondrial tumor suppressor 1
chr2_-_5714490 2.73 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr10_-_81430966 2.58 ENSMUST00000117966.1
Nfic
nuclear factor I/C
chr4_+_139622842 2.55 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr2_-_130642770 2.53 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chrX_-_136868537 2.40 ENSMUST00000058814.6
Rab9b
RAB9B, member RAS oncogene family
chr9_-_97018823 2.31 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr16_+_44173239 2.26 ENSMUST00000119746.1
Gm608
predicted gene 608
chr10_-_127666598 2.25 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr12_+_8771405 2.24 ENSMUST00000171158.1
Sdc1
syndecan 1
chr4_+_83525540 2.24 ENSMUST00000053414.6
ENSMUST00000126429.1
Ccdc171
coiled-coil domain containing 171
chr9_+_46012810 2.23 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr7_-_140102367 2.21 ENSMUST00000142105.1
Fuom
fucose mutarotase
chr19_+_6497772 2.17 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2
neurexin II
chrX_+_161717498 2.13 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr5_+_30588078 2.12 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr9_-_21927515 2.11 ENSMUST00000178988.1
ENSMUST00000046831.9
Tmem205
transmembrane protein 205
chr19_+_53903351 2.11 ENSMUST00000025931.6
ENSMUST00000165617.1
Pdcd4
programmed cell death 4
chr7_+_26307190 2.09 ENSMUST00000098657.3
Cyp2a4
cytochrome P450, family 2, subfamily a, polypeptide 4
chr12_+_8771317 2.07 ENSMUST00000020911.7
Sdc1
syndecan 1
chr11_-_100770926 1.85 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc
GH3 domain containing
chr7_-_80403315 1.84 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr10_-_127666673 1.80 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr9_+_21927471 1.78 ENSMUST00000170304.1
ENSMUST00000006403.6
Ccdc159
coiled-coil domain containing 159
chr7_-_140102326 1.74 ENSMUST00000128527.1
Fuom
fucose mutarotase
chr2_+_140395446 1.62 ENSMUST00000110061.1
Macrod2
MACRO domain containing 2
chr4_-_129239165 1.55 ENSMUST00000097873.3
C77080
expressed sequence C77080
chr5_+_148959263 1.54 ENSMUST00000135240.1
Gm15409
predicted gene 15409
chr15_+_57694651 1.54 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr2_-_90580578 1.46 ENSMUST00000168621.2
Ptprj
protein tyrosine phosphatase, receptor type, J
chr15_+_87625214 1.44 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr7_-_80402743 1.44 ENSMUST00000122232.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr8_+_111536492 1.43 ENSMUST00000168428.1
ENSMUST00000171182.1
Znrf1
zinc and ring finger 1
chr9_+_46012822 1.42 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3
SIK family kinase 3
chr4_-_148159571 1.40 ENSMUST00000167160.1
ENSMUST00000151246.1
Fbxo44
F-box protein 44
chr10_-_54075702 1.39 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr10_-_59616667 1.39 ENSMUST00000020312.6
Mcu
mitochondrial calcium uniporter
chr5_+_127632238 1.38 ENSMUST00000118139.1
Glt1d1
glycosyltransferase 1 domain containing 1
chr10_-_54075730 1.37 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a
mannosidase 1, alpha
chr1_+_59482133 1.36 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7
frizzled homolog 7 (Drosophila)
chr11_-_97574040 1.35 ENSMUST00000107593.1
Srcin1
SRC kinase signaling inhibitor 1
chr16_-_46496772 1.35 ENSMUST00000149901.1
ENSMUST00000096052.2
Pvrl3
poliovirus receptor-related 3
chr2_+_140395309 1.35 ENSMUST00000110067.1
ENSMUST00000110064.1
ENSMUST00000110063.1
ENSMUST00000110062.1
ENSMUST00000078027.5
ENSMUST00000043836.7
Macrod2
MACRO domain containing 2
chr2_+_32606979 1.33 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr13_+_58402546 1.31 ENSMUST00000042450.8
Rmi1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr4_-_57300362 1.30 ENSMUST00000153926.1
Ptpn3
protein tyrosine phosphatase, non-receptor type 3
chr16_-_96082389 1.28 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
Brwd1
bromodomain and WD repeat domain containing 1
chr12_+_41024090 1.28 ENSMUST00000132121.1
Immp2l
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_-_3863895 1.28 ENSMUST00000070552.7
Osbp2
oxysterol binding protein 2
chrX_+_141475385 1.27 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5
collagen, type IV, alpha 5
chr17_+_43801823 1.26 ENSMUST00000044895.5
Rcan2
regulator of calcineurin 2
chr2_-_120314141 1.26 ENSMUST00000054651.7
Pla2g4f
phospholipase A2, group IVF
chr7_+_28180226 1.25 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr17_+_80944611 1.24 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr16_+_20733104 1.18 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd
chordin
chr17_-_32947372 1.17 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr17_-_15375969 1.16 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr1_-_161034794 1.16 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
Zbtb37
zinc finger and BTB domain containing 37
chr11_-_97573929 1.15 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1
SRC kinase signaling inhibitor 1
chr11_-_72796028 1.15 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr3_+_117575268 1.14 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr17_-_32947389 1.14 ENSMUST00000075253.6
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr4_+_97777606 1.14 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia
nuclear factor I/A
chr2_-_173276144 1.13 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr7_-_140102384 1.12 ENSMUST00000120034.1
ENSMUST00000121115.1
ENSMUST00000026539.7
Fuom
fucose mutarotase
chr1_+_36511867 1.11 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3
cyclin M3
chr19_-_43674844 1.11 ENSMUST00000046038.7
Slc25a28
solute carrier family 25, member 28
chr1_-_93478785 1.09 ENSMUST00000170883.1
Hdlbp
high density lipoprotein (HDL) binding protein
chr8_+_12385769 1.09 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr2_+_18677002 1.09 ENSMUST00000028071.6
Bmi1
Bmi1 polycomb ring finger oncogene
chr13_-_29984219 1.08 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr19_-_44029201 1.08 ENSMUST00000026211.8
Cyp2c44
cytochrome P450, family 2, subfamily c, polypeptide 44
chr2_+_69897220 1.08 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr14_-_70520254 1.07 ENSMUST00000022693.7
Bmp1
bone morphogenetic protein 1
chr16_-_46496955 1.02 ENSMUST00000023335.6
ENSMUST00000023334.8
Pvrl3
poliovirus receptor-related 3
chr15_+_25414175 1.01 ENSMUST00000069992.5
Gm5468
predicted gene 5468
chr19_-_29812952 1.00 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr14_-_39472825 0.99 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3
neuregulin 3
chr17_-_70851189 0.99 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr2_+_31314303 0.98 ENSMUST00000113532.2
Hmcn2
hemicentin 2
chr9_+_60794468 0.97 ENSMUST00000050183.6
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr11_-_100759740 0.97 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr9_+_108080436 0.96 ENSMUST00000035211.7
ENSMUST00000162886.1
Mst1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_+_28180272 0.94 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr4_+_107178399 0.93 ENSMUST00000030361.4
ENSMUST00000128123.1
ENSMUST00000106753.1
Tmem59
transmembrane protein 59
chr2_+_91257323 0.93 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr7_+_100706623 0.93 ENSMUST00000107042.1
Fam168a
family with sequence similarity 168, member A
chr11_+_69765970 0.89 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4
zinc finger and BTB domain containing 4
chr2_+_18064564 0.89 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr10_-_7956223 0.87 ENSMUST00000146444.1
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr8_-_91134027 0.86 ENSMUST00000125257.1
Aktip
thymoma viral proto-oncogene 1 interacting protein
chr4_-_124850670 0.86 ENSMUST00000163946.1
ENSMUST00000106190.3
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr12_-_98737405 0.85 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr13_-_103920508 0.85 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip
Erbb2 interacting protein
chr7_+_100706702 0.84 ENSMUST00000049053.7
Fam168a
family with sequence similarity 168, member A
chr12_+_108792946 0.84 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr15_+_102921103 0.84 ENSMUST00000001700.6
Hoxc13
homeobox C13
chr17_+_46383725 0.83 ENSMUST00000113481.1
ENSMUST00000138127.1
Zfp318
zinc finger protein 318
chr8_-_93810225 0.83 ENSMUST00000181864.1
Gm26843
predicted gene, 26843
chr13_-_103920295 0.83 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr16_-_96082513 0.83 ENSMUST00000113827.1
Brwd1
bromodomain and WD repeat domain containing 1
chr13_+_51100810 0.81 ENSMUST00000095797.5
Spin1
spindlin 1
chr8_-_91133942 0.81 ENSMUST00000120213.1
ENSMUST00000109609.2
Aktip
thymoma viral proto-oncogene 1 interacting protein
chr18_+_36281069 0.80 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr4_+_122995944 0.79 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr4_+_122996035 0.79 ENSMUST00000030407.7
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr11_+_50602072 0.78 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr5_+_135064206 0.77 ENSMUST00000071263.5
Dnajc30
DnaJ (Hsp40) homolog, subfamily C, member 30
chr3_-_139075178 0.76 ENSMUST00000098574.2
ENSMUST00000029796.6
Rap1gds1
RAP1, GTP-GDP dissociation stimulator 1
chr4_-_124850473 0.76 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr16_-_84835484 0.75 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr16_+_20673264 0.75 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr3_+_121426495 0.74 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr1_-_168432270 0.74 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr9_+_119402444 0.74 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b
activin receptor IIB
chr2_+_18064645 0.73 ENSMUST00000114680.2
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_168431695 0.72 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr1_-_56971762 0.71 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr9_+_65630552 0.70 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr11_-_116307168 0.70 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr10_+_39732099 0.70 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr4_-_126533472 0.69 ENSMUST00000084289.4
Ago4
argonaute RISC catalytic subunit 4
chr2_-_65238573 0.68 ENSMUST00000090896.3
ENSMUST00000155082.1
Cobll1
Cobl-like 1
chr9_+_25481547 0.68 ENSMUST00000040677.5
Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
chr4_+_131921771 0.67 ENSMUST00000094666.3
Tmem200b
transmembrane protein 200B
chr2_-_20968881 0.66 ENSMUST00000114594.1
Arhgap21
Rho GTPase activating protein 21
chr10_-_84440591 0.66 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr18_-_31949571 0.66 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr11_-_102296618 0.66 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3
ataxin 7-like 3
chr1_-_16519284 0.65 ENSMUST00000162751.1
ENSMUST00000027052.6
ENSMUST00000149320.2
Stau2
staufen (RNA binding protein) homolog 2 (Drosophila)
chr9_+_118478182 0.64 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr14_+_70530819 0.63 ENSMUST00000047331.6
Lgi3
leucine-rich repeat LGI family, member 3
chr16_-_84835557 0.63 ENSMUST00000138279.1
ENSMUST00000023608.7
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr11_+_23306884 0.62 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr18_-_39489157 0.61 ENSMUST00000131885.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr11_-_5261558 0.60 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr13_-_9764431 0.60 ENSMUST00000154994.1
ENSMUST00000146039.1
ENSMUST00000110635.1
ENSMUST00000110638.1
Zmynd11
zinc finger, MYND domain containing 11
chr9_+_118478344 0.60 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr4_-_124850652 0.60 ENSMUST00000125776.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chrX_-_152368680 0.60 ENSMUST00000070316.5
Gpr173
G-protein coupled receptor 173
chr1_-_16519201 0.59 ENSMUST00000159558.1
ENSMUST00000054668.6
ENSMUST00000162627.1
ENSMUST00000162007.1
ENSMUST00000128957.2
ENSMUST00000115359.3
ENSMUST00000151888.1
Stau2
staufen (RNA binding protein) homolog 2 (Drosophila)
chr19_+_6047081 0.59 ENSMUST00000025723.8
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr5_-_65492984 0.57 ENSMUST00000139122.1
Smim14
small integral membrane protein 14
chr12_+_102283116 0.57 ENSMUST00000101114.4
ENSMUST00000150795.1
Rin3
Ras and Rab interactor 3
chr7_-_16874845 0.57 ENSMUST00000181501.1
9330104G04Rik
RIKEN cDNA 9330104G04 gene
chrX_-_20617574 0.56 ENSMUST00000116621.1
Ndufb11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr2_-_28840274 0.56 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4
general transcription factor IIIC, polypeptide 4
chr5_-_106696530 0.56 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644
zinc finger protein 644
chr7_-_119184374 0.56 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr10_+_79716588 0.56 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr6_+_8949670 0.55 ENSMUST00000060369.3
Nxph1
neurexophilin 1
chr8_-_121652895 0.55 ENSMUST00000046386.4
Zcchc14
zinc finger, CCHC domain containing 14
chr19_+_60889749 0.54 ENSMUST00000003313.8
Grk5
G protein-coupled receptor kinase 5
chr1_+_105990384 0.54 ENSMUST00000119166.1
Zcchc2
zinc finger, CCHC domain containing 2
chr7_+_16310412 0.54 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr11_-_116306696 0.54 ENSMUST00000133468.1
ENSMUST00000106411.3
ENSMUST00000106413.3
ENSMUST00000021147.7
Exoc7
exocyst complex component 7
chr13_-_71963713 0.54 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr5_-_135064063 0.54 ENSMUST00000111205.1
ENSMUST00000141309.1
Wbscr22
Williams Beuren syndrome chromosome region 22
chr17_+_37050631 0.54 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_+_35541275 0.53 ENSMUST00000120756.1
Sema5b
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr13_-_95223045 0.53 ENSMUST00000162292.1
Pde8b
phosphodiesterase 8B
chr1_-_87510306 0.53 ENSMUST00000027477.8
Ngef
neuronal guanine nucleotide exchange factor
chr9_-_59486323 0.53 ENSMUST00000165322.1
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr17_+_43667389 0.52 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr6_-_113377712 0.52 ENSMUST00000113107.1
ENSMUST00000113106.1
Tada3
transcriptional adaptor 3
chr17_-_22361400 0.52 ENSMUST00000115535.2
Zfp944
zinc finger protein 944
chr6_-_113377866 0.52 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr2_-_84715160 0.52 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr10_+_43479140 0.51 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3
BEN domain containing 3
chr13_-_58113592 0.51 ENSMUST00000160860.1
Klhl3
kelch-like 3
chr9_-_21592805 0.51 ENSMUST00000034700.7
ENSMUST00000180365.1
ENSMUST00000078572.7
Yipf2
Yip1 domain family, member 2
chr11_-_62731865 0.51 ENSMUST00000150336.1
Zfp287
zinc finger protein 287
chr18_-_38284391 0.50 ENSMUST00000025311.5
Pcdh12
protocadherin 12
chr2_-_153632679 0.50 ENSMUST00000109782.1
Commd7
COMM domain containing 7
chr6_-_99666762 0.49 ENSMUST00000032151.2
Eif4e3
eukaryotic translation initiation factor 4E member 3
chr17_+_26933070 0.49 ENSMUST00000073724.5
Phf1
PHD finger protein 1
chr11_-_116306652 0.48 ENSMUST00000126731.1
Exoc7
exocyst complex component 7
chr1_-_124045247 0.48 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chr7_-_27396542 0.48 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr17_-_80728026 0.46 ENSMUST00000112389.2
ENSMUST00000025089.7
Map4k3
mitogen-activated protein kinase kinase kinase kinase 3
chr4_+_47353222 0.46 ENSMUST00000007757.8
Tgfbr1
transforming growth factor, beta receptor I
chr11_+_115420138 0.45 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2
potassium channel tetramerisation domain containing 2
chr13_-_38151792 0.45 ENSMUST00000078232.1
Gm10129
predicted gene 10129
chr17_-_79715034 0.44 ENSMUST00000024894.1
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr18_+_61045139 0.44 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
chr2_+_128818104 0.43 ENSMUST00000110325.1
Tmem87b
transmembrane protein 87B
chr11_+_115420059 0.43 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr19_+_48206025 0.43 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr9_+_21592722 0.43 ENSMUST00000062125.10
1810026J23Rik
RIKEN cDNA 1810026J23 gene
chr3_+_156561950 0.42 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1
neuronal growth regulator 1
chr14_-_55784027 0.42 ENSMUST00000170223.1
Adcy4
adenylate cyclase 4
chr1_+_105990652 0.42 ENSMUST00000118196.1
Zcchc2
zinc finger, CCHC domain containing 2
chr16_-_34262945 0.42 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf15

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.4 4.3 GO:0048627 myoblast development(GO:0048627)
0.8 2.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.8 3.3 GO:0090472 dibasic protein processing(GO:0090472)
0.8 3.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.7 2.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.6 5.1 GO:0006004 fucose metabolic process(GO:0006004)
0.6 1.8 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.6 4.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.4 1.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.4 3.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.4 1.2 GO:0097101 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.3 1.4 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 1.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.3 0.9 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3 1.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 2.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 0.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.3 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 0.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 1.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 0.7 GO:1905223 epicardium morphogenesis(GO:1905223)
0.2 1.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 1.2 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 3.8 GO:0072189 ureter development(GO:0072189)
0.2 2.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.5 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 1.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 1.0 GO:0060596 mammary placode formation(GO:0060596)
0.2 2.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.7 GO:2000535 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 4.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 5.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) endothelial cell-cell adhesion(GO:0071603)
0.1 0.4 GO:0072277 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.7 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 1.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 1.3 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.5 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0035106 operant conditioning(GO:0035106)
0.1 0.4 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414)
0.1 1.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.4 GO:1902868 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 1.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 2.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.4 GO:0072137 cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 3.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.8 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.8 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.4 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 1.9 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 0.4 GO:0045358 N-terminal peptidyl-lysine acetylation(GO:0018076) negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 1.3 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 2.3 GO:0006691 leukotriene metabolic process(GO:0006691)
0.1 1.8 GO:0030325 adrenal gland development(GO:0030325)
0.1 1.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.6 GO:0071321 cellular response to cGMP(GO:0071321) potassium ion import across plasma membrane(GO:1990573)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.1 2.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.5 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1 0.7 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 3.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 1.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 0.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 1.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.6 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.3 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0051044 regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0097168 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 2.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 1.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 1.1 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.6 GO:1902236 retrograde protein transport, ER to cytosol(GO:0030970) negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.4 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0098743 cell aggregation(GO:0098743)
0.0 0.7 GO:0017145 stem cell division(GO:0017145)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.4 GO:1990246 uniplex complex(GO:1990246)
0.3 2.9 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.0 GO:0043293 apoptosome(GO:0043293)
0.2 1.7 GO:0070695 FHF complex(GO:0070695)
0.2 3.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 1.3 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.6 GO:0098855 HCN channel complex(GO:0098855)
0.2 1.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.9 GO:0097413 Lewy body(GO:0097413)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.7 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 2.7 GO:0030175 filopodium(GO:0030175)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 4.1 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0042806 fucose binding(GO:0042806)
1.1 3.2 GO:0031752 D4 dopamine receptor binding(GO:0031751) D5 dopamine receptor binding(GO:0031752)
0.3 2.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 3.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 2.9 GO:0019841 retinol binding(GO:0019841)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.6 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.2 2.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 1.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 2.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 3.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 0.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 2.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0000182 rDNA binding(GO:0000182)
0.0 2.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 1.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.0 1.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.1 GO:0020037 heme binding(GO:0020037)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 13.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 4.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.4 PID BMP PATHWAY BMP receptor signaling
0.0 4.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 2.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME MEIOSIS Genes involved in Meiosis
0.0 2.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives