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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Lhx4

Z-value: 0.43

Motif logo

Transcription factors associated with Lhx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000026468.8 LIM homeobox protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx4mm10_v2_chr1_-_155742120_1557421360.096.1e-01Click!

Activity profile of Lhx4 motif

Sorted Z-values of Lhx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41446062 2.15 ENSMUST00000095999.5
predicted gene 10334
chr2_-_160619971 2.07 ENSMUST00000109473.1
predicted gene 14221
chr6_-_41377604 2.03 ENSMUST00000096003.5
protease, serine, 3
chr14_+_80000292 1.65 ENSMUST00000088735.3
olfactomedin 4
chr10_+_75566257 1.20 ENSMUST00000129232.1
ENSMUST00000143792.1
gamma-glutamyltransferase 1
chr14_+_27000362 1.12 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr5_-_62765618 1.04 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_78684262 0.98 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr1_-_89933290 0.93 ENSMUST00000036954.7
gastrulation brain homeobox 2
chr15_+_98571004 0.80 ENSMUST00000023728.6
RIKEN cDNA 4930415O20 gene
chr16_-_22161450 0.74 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr16_-_76022266 0.72 ENSMUST00000114240.1
SAM domain, SH3 domain and nuclear localization signals, 1
chrX_+_9885622 0.67 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr3_+_68869563 0.64 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr7_+_45621805 0.61 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr6_-_145865302 0.61 ENSMUST00000111703.1
basic helix-loop-helix family, member e41
chr4_+_145585166 0.60 ENSMUST00000105739.1
ENSMUST00000119718.1
predicted gene 13212
chr2_-_72813665 0.57 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chrX_+_150547375 0.57 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr11_+_84129649 0.56 ENSMUST00000133811.1
acetyl-Coenzyme A carboxylase alpha
chr10_+_37139558 0.54 ENSMUST00000062667.3
RIKEN cDNA 5930403N24 gene
chr19_+_10015016 0.52 ENSMUST00000137637.1
ENSMUST00000149967.1
RAB3A interacting protein (rabin3)-like 1
chr6_-_117214048 0.49 ENSMUST00000170447.1
ribosomal protein L28, pseudogene 4
chr6_-_136941887 0.48 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_66365905 0.47 ENSMUST00000107486.1
predicted gene 10974
chr4_+_34893772 0.46 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chrX_-_74246534 0.46 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr17_-_24073479 0.46 ENSMUST00000017090.5
potassium channel tetramerisation domain containing 5
chrX_-_139871637 0.45 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr1_-_163289214 0.44 ENSMUST00000183691.1
paired related homeobox 1
chr4_+_147132038 0.44 ENSMUST00000084149.3
predicted gene 13139
chr7_+_43427622 0.44 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr13_+_120308146 0.43 ENSMUST00000081558.7
cDNA sequence BC147527
chr18_+_44104407 0.42 ENSMUST00000081271.5
serine peptidase inhibitor, Kazal type 11
chr6_-_30958990 0.42 ENSMUST00000101589.3
Kruppel-like factor 14
chr13_-_52530827 0.42 ENSMUST00000057442.6
DIRAS family, GTP-binding RAS-like 2
chr6_+_29859686 0.42 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr15_-_42676967 0.41 ENSMUST00000022921.5
angiopoietin 1
chr4_+_146097312 0.41 ENSMUST00000105730.1
ENSMUST00000091878.5
predicted gene 13051
chr5_-_108795352 0.39 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr8_+_121127827 0.39 ENSMUST00000181609.1
forkhead box L1
chrX_-_74246364 0.39 ENSMUST00000130007.1
filamin, alpha
chr10_+_79996479 0.39 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr3_-_17230976 0.39 ENSMUST00000177874.1
predicted gene 5283
chr13_-_105271039 0.36 ENSMUST00000069686.6
ring finger protein 180
chr6_-_129876659 0.36 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr4_-_3938354 0.34 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr4_+_146610961 0.34 ENSMUST00000130825.1
predicted gene 13248
chr9_+_96258697 0.33 ENSMUST00000179416.1
transcription factor Dp 2
chr2_-_152580300 0.33 ENSMUST00000053180.3
defensin beta 19
chr6_+_29859662 0.33 ENSMUST00000128927.2
S-adenosylhomocysteine hydrolase-like 2
chr14_-_110755100 0.33 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr2_-_177267036 0.32 ENSMUST00000108963.1
predicted gene 14409
chr15_-_36879816 0.32 ENSMUST00000100713.2
predicted gene 10384
chr14_+_53337122 0.31 ENSMUST00000179580.1
T cell receptor alpha variable 13N-3
chr9_-_49798905 0.31 ENSMUST00000114476.2
neural cell adhesion molecule 1
chr7_-_81493725 0.31 ENSMUST00000119121.1
adaptor-related protein complex 3, beta 2 subunit
chr3_-_96452306 0.30 ENSMUST00000093126.4
ENSMUST00000098841.3
cDNA sequence BC107364
chr11_+_76904513 0.30 ENSMUST00000072633.3
transmembrane and immunoglobulin domain containing 1
chr8_+_40354303 0.30 ENSMUST00000136835.1
mitochondrial calcium uptake family, member 3
chr14_+_53032902 0.29 ENSMUST00000179512.1
T cell receptor alpha variable 13D-3
chr4_+_15881255 0.29 ENSMUST00000029876.1
calbindin 1
chr5_+_20702129 0.28 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_20090538 0.28 ENSMUST00000072519.5
engulfment and cell motility 1
chr2_-_73453918 0.28 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr2_-_164171113 0.27 ENSMUST00000045196.3
K+ voltage-gated channel, subfamily S, 1
chr4_-_147809788 0.27 ENSMUST00000105734.3
ENSMUST00000176201.1
predicted gene 13157
predicted gene 20707
chr3_+_89715016 0.27 ENSMUST00000098924.2
adenosine deaminase, RNA-specific
chr14_+_58893465 0.27 ENSMUST00000079960.1
ribosomal protein L13, pseudogene 3
chr10_-_127189981 0.26 ENSMUST00000019611.7
Rho guanine nucleotide exchange factor (GEF) 25
chr9_+_119063429 0.26 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr15_-_56694525 0.26 ENSMUST00000050544.7
hyaluronan synthase 2
chr17_+_46650328 0.25 ENSMUST00000043464.7
cullin 7
chr2_-_7396192 0.25 ENSMUST00000137733.2
CUGBP, Elav-like family member 2
chr13_-_89742244 0.25 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
versican
chr12_+_38783503 0.25 ENSMUST00000159334.1
ets variant gene 1
chr17_+_34592248 0.25 ENSMUST00000038149.6
pre B cell leukemia homeobox 2
chr1_+_153665666 0.24 ENSMUST00000111814.1
ENSMUST00000111810.1
regulator of G-protein signaling 8
chr8_+_34054622 0.24 ENSMUST00000149618.1
predicted gene 9951
chr11_+_58421103 0.23 ENSMUST00000013797.2
RIKEN cDNA 1810065E05 gene
chr13_+_20090500 0.23 ENSMUST00000165249.2
engulfment and cell motility 1
chr10_+_116966274 0.23 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr8_-_106573461 0.23 ENSMUST00000073722.5
predicted pseudogene 10073
chr16_-_21995478 0.22 ENSMUST00000074230.4
ENSMUST00000060673.6
lipase, member H
chr12_-_12941827 0.22 ENSMUST00000043396.7
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr9_-_49798729 0.22 ENSMUST00000166811.2
neural cell adhesion molecule 1
chrX_-_102157065 0.22 ENSMUST00000056904.2
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr4_+_148901128 0.22 ENSMUST00000147270.1
castor zinc finger 1
chr6_+_136518820 0.22 ENSMUST00000032335.6
activating transcription factor 7 interacting protein
chr18_+_60774675 0.22 ENSMUST00000118551.1
ribosomal protein S14
chr9_+_100597686 0.21 ENSMUST00000124487.1
stromal antigen 1
chr1_+_63176818 0.21 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr19_-_55241236 0.21 ENSMUST00000069183.6
guanylate cyclase 2g
chr1_+_180111339 0.21 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr10_-_62507737 0.21 ENSMUST00000020271.6
serglycin
chr17_-_67950908 0.21 ENSMUST00000164647.1
Rho GTPase activating protein 28
chrX_-_160906998 0.21 ENSMUST00000069417.5
gap junction protein, alpha 6
chr3_+_24333046 0.21 ENSMUST00000077389.6
predicted gene 7536
chr4_+_146502027 0.20 ENSMUST00000105735.2
predicted gene 13247
chr3_-_41742471 0.20 ENSMUST00000026866.8
sodium channel and clathrin linker 1
chr4_+_146161909 0.20 ENSMUST00000131932.1
zinc finger protein 600
chr9_+_120929216 0.20 ENSMUST00000130466.1
catenin (cadherin associated protein), beta 1
chr1_-_172027251 0.20 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr4_+_147553277 0.20 ENSMUST00000139784.1
ENSMUST00000143885.1
ENSMUST00000081742.6
predicted gene 13154
chr5_+_34999111 0.20 ENSMUST00000114283.1
regulator of G-protein signaling 12
chr12_+_38783455 0.20 ENSMUST00000161980.1
ENSMUST00000160701.1
ets variant gene 1
chr7_+_18245347 0.20 ENSMUST00000066780.4
MHC I like leukocyte 1
chr3_-_59220150 0.20 ENSMUST00000170388.1
purinergic receptor P2Y, G-protein coupled 12
chr2_-_170194033 0.19 ENSMUST00000180625.1
predicted gene, 17619
chr18_+_60774510 0.19 ENSMUST00000025511.3
ribosomal protein S14
chr6_+_30610984 0.19 ENSMUST00000062758.4
carboxypeptidase A5
chr16_-_29544852 0.18 ENSMUST00000039090.8
ATPase type 13A4
chr17_-_26099257 0.18 ENSMUST00000053575.3
predicted gene 8186
chr8_+_83666827 0.18 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr16_-_74411292 0.18 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr4_+_102991784 0.18 ENSMUST00000140654.1
ENSMUST00000169211.1
Tctex1 domain containing 1
chr6_-_115037824 0.18 ENSMUST00000174848.1
ENSMUST00000032461.5
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
chr8_+_57332111 0.18 ENSMUST00000181638.1
RIKEN cDNA 5033428I22 gene
chr2_+_78051155 0.18 ENSMUST00000145972.1
RIKEN cDNA 4930440I19 gene
chr1_-_36273425 0.17 ENSMUST00000056946.6
neuralized homolog 3 homolog (Drosophila)
chr2_-_7395879 0.17 ENSMUST00000182404.1
CUGBP, Elav-like family member 2
chr2_+_86007778 0.17 ENSMUST00000062166.1
olfactory receptor 1032
chr12_-_27342696 0.17 ENSMUST00000079063.5
SRY-box containing gene 11
chr1_-_165160773 0.17 ENSMUST00000027859.5
T-box 19
chr3_+_53845086 0.16 ENSMUST00000108014.1
predicted gene 10985
chr3_-_141982224 0.16 ENSMUST00000029948.8
bone morphogenetic protein receptor, type 1B
chr10_-_76110956 0.16 ENSMUST00000120757.1
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr13_-_102906046 0.16 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr17_-_14694223 0.16 ENSMUST00000170872.1
thrombospondin 2
chr5_+_34999046 0.16 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr14_+_57524734 0.16 ENSMUST00000089494.4
interleukin 17D
chr5_+_34999070 0.15 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr7_+_30458280 0.15 ENSMUST00000126297.1
nephrosis 1, nephrin
chr11_+_76904475 0.15 ENSMUST00000142166.1
transmembrane and immunoglobulin domain containing 1
chr11_+_115334731 0.15 ENSMUST00000106543.1
ENSMUST00000019006.4
otopetrin 3
chr3_+_14480692 0.15 ENSMUST00000037321.7
ENSMUST00000120484.1
ENSMUST00000120801.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr12_+_38780284 0.15 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr2_-_85675173 0.15 ENSMUST00000099917.1
olfactory receptor 1006
chr12_-_103694657 0.14 ENSMUST00000117053.1
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr7_+_16959714 0.14 ENSMUST00000038163.6
PNMA-like 1
chr1_-_138175238 0.14 ENSMUST00000182536.1
protein tyrosine phosphatase, receptor type, C
chr14_-_104522615 0.14 ENSMUST00000022716.2
ring finger protein 219
chr15_-_50889691 0.13 ENSMUST00000165201.2
ENSMUST00000184458.1
trichorhinophalangeal syndrome I (human)
chr17_+_17402672 0.13 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr10_+_116143881 0.13 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr11_+_96286623 0.13 ENSMUST00000049352.7
homeobox B7
chr12_+_3954943 0.13 ENSMUST00000020990.5
pro-opiomelanocortin-alpha
chr13_-_102905740 0.13 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr2_+_163658370 0.13 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
protein kinase inhibitor, gamma
chr9_+_64281575 0.13 ENSMUST00000034964.6
timeless interacting protein
chr3_+_102734496 0.12 ENSMUST00000029451.5
tetraspanin 2
chr7_-_46667375 0.12 ENSMUST00000107669.2
tryptophan hydroxylase 1
chr7_-_45830776 0.12 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr15_+_16778101 0.12 ENSMUST00000026432.6
cadherin 9
chr2_+_110721587 0.12 ENSMUST00000111017.2
mucin 15
chr9_+_21526144 0.11 ENSMUST00000086361.5
ENSMUST00000179459.1
ENSMUST00000173769.2
cDNA sequence AB124611
chr7_-_37773555 0.11 ENSMUST00000176534.1
zinc finger protein 536
chr19_+_46396885 0.11 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
suppressor of fused homolog (Drosophila)
chr13_+_93304799 0.11 ENSMUST00000080127.5
homer homolog 1 (Drosophila)
chr1_-_138175283 0.11 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
protein tyrosine phosphatase, receptor type, C
chr9_-_104337700 0.11 ENSMUST00000112590.2
ENSMUST00000062723.6
acid phosphatase, prostate
chr2_+_110721340 0.11 ENSMUST00000111016.2
mucin 15
chr3_+_18054258 0.11 ENSMUST00000026120.6
basic helix-loop-helix family, member e22
chr1_-_138175126 0.11 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr9_-_71896047 0.11 ENSMUST00000184448.1
transcription factor 12
chr6_-_128275577 0.11 ENSMUST00000130454.1
TEA domain family member 4
chr13_-_97747399 0.11 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr11_+_62847111 0.10 ENSMUST00000150989.1
ENSMUST00000176577.1
F-box and WD-40 domain protein 10
chr3_+_138352378 0.10 ENSMUST00000090166.4
alcohol dehydrogenase 6B (class V)
chr6_-_3399545 0.10 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr1_-_22315792 0.10 ENSMUST00000164877.1
regulating synaptic membrane exocytosis 1
chr2_+_3424123 0.10 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr2_-_79456750 0.10 ENSMUST00000041099.4
neurogenic differentiation 1
chr2_+_36230426 0.10 ENSMUST00000062069.5
prostaglandin-endoperoxide synthase 1
chr19_+_5474681 0.10 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr1_+_85575676 0.10 ENSMUST00000178024.1
RIKEN cDNA G530012D1 gene
chr16_-_90810365 0.10 ENSMUST00000140920.1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr2_-_155945282 0.10 ENSMUST00000040162.2
growth differentiation factor 5
chrX_-_75578188 0.09 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr4_+_147492417 0.09 ENSMUST00000105721.2
predicted gene 13152
chr1_-_38821215 0.09 ENSMUST00000039612.4
LON peptidase N-terminal domain and ring finger 2
chr16_-_56024628 0.09 ENSMUST00000119981.1
ENSMUST00000096021.3
PEST proteolytic signal containing nuclear protein
chr10_-_35711891 0.09 ENSMUST00000080898.2
S-adenosylmethionine decarboxylase 2
chr5_-_122821298 0.08 ENSMUST00000086216.4
anaphase-promoting complex subunit 5
chr9_+_7571396 0.08 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr13_-_58354862 0.08 ENSMUST00000043605.5
kinesin family member 27
chr19_+_46397009 0.08 ENSMUST00000118440.1
suppressor of fused homolog (Drosophila)
chr18_+_22345089 0.08 ENSMUST00000120223.1
ENSMUST00000097655.3
additional sex combs like 3 (Drosophila)
chr14_+_75455957 0.08 ENSMUST00000164848.1
seven in absentia homolog 3 (Drosophila)
chr1_-_133661318 0.08 ENSMUST00000179598.1
ENSMUST00000027736.6
zinc finger, BED domain containing 6
zinc finger CCCH type containing 11A
chr6_+_29859374 0.08 ENSMUST00000115238.3
S-adenosylhomocysteine hydrolase-like 2
chr2_-_7395968 0.08 ENSMUST00000002176.6
CUGBP, Elav-like family member 2
chr14_+_26122609 0.08 ENSMUST00000100810.6
doubl homeobox B-like 2
chr5_-_86745787 0.07 ENSMUST00000161306.1
transmembrane protease, serine 11e
chr3_-_67375163 0.07 ENSMUST00000166353.1
predicted gene, 17402
chr9_-_22259887 0.07 ENSMUST00000086281.4
zinc finger protein 599
chr4_+_146514920 0.07 ENSMUST00000140089.1
ENSMUST00000179175.1
predicted gene 13247
chr11_+_62847062 0.07 ENSMUST00000036085.4
F-box and WD-40 domain protein 10
chr2_+_4300462 0.07 ENSMUST00000175669.1
FERM domain containing 4A
chr11_+_6560183 0.07 ENSMUST00000109722.2
cerebral cavernous malformation 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 0.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 1.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.6 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.1 0.9 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 1.1 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.5 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.2 GO:1904173 regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.1 0.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0061076 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.1 0.4 GO:2000473 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 0.3 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.2 GO:0033375 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0060168 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.5 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 1.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:1904753 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 4.0 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.1 GO:2000849 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.4 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031523 Myb complex(GO:0031523)
0.1 1.7 GO:0042581 specific granule(GO:0042581)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071820 N-box binding(GO:0071820)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 2.1 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0070411 alpha-catenin binding(GO:0045294) I-SMAD binding(GO:0070411) histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis