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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nfatc1

Z-value: 1.31

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000033016.9 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1mm10_v2_chr18_-_80713062_807130800.372.6e-02Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_3023547 7.14 ENSMUST00000099046.3
predicted gene 10718
chr9_+_3000922 6.79 ENSMUST00000151376.2
predicted gene 10722
chr2_-_98667264 6.50 ENSMUST00000099683.1
predicted gene 10800
chr9_+_3027439 6.21 ENSMUST00000177875.1
ENSMUST00000179982.1
predicted gene 10717
chr16_-_16863817 6.02 ENSMUST00000124890.1
immunoglobulin lambda-like polypeptide 1
chr9_+_3013140 5.88 ENSMUST00000143083.2
predicted gene 10721
chr7_-_142679533 5.39 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
insulin II
chr9_+_3017408 4.95 ENSMUST00000099049.3
predicted gene 10719
chr9_+_3034599 4.74 ENSMUST00000178641.1
predicted gene, 17535
chr19_+_52264323 4.65 ENSMUST00000039652.4
insulin I
chr4_+_134864536 4.35 ENSMUST00000030627.7
Rh blood group, D antigen
chr9_+_3025417 4.22 ENSMUST00000075573.6
predicted gene 10717
chr14_-_19418930 4.09 ENSMUST00000177817.1
predicted gene, 21738
chr9_+_3015654 4.09 ENSMUST00000099050.3
predicted gene 10720
chr2_+_157560078 4.08 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr9_+_3005125 3.95 ENSMUST00000179881.1
predicted gene 11168
chr9_+_3037111 3.88 ENSMUST00000177969.1
predicted gene 10715
chr9_+_3004457 3.74 ENSMUST00000178348.1
predicted gene 11168
chr7_-_134232005 3.25 ENSMUST00000134504.1
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr9_+_3036877 3.04 ENSMUST00000155807.2
predicted gene 10715
chr4_-_44710408 3.04 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
paired box gene 5
chr9_+_3018753 3.02 ENSMUST00000179272.1
predicted gene 10719
chr1_-_82768449 2.98 ENSMUST00000027331.2
transmembrane 4 L six family member 20
chr16_+_45610380 2.96 ENSMUST00000161347.2
ENSMUST00000023339.4
germinal center associated, signaling and motility
chr14_+_118787894 2.95 ENSMUST00000047761.6
ENSMUST00000071546.7
claudin 10
chr7_+_110773658 2.87 ENSMUST00000143786.1
adenosine monophosphate deaminase 3
chr7_+_110774240 2.78 ENSMUST00000147587.1
adenosine monophosphate deaminase 3
chr2_+_98662227 2.78 ENSMUST00000099684.3
predicted gene 10801
chr7_+_30423266 2.70 ENSMUST00000046177.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr7_+_99535652 2.63 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr15_-_79164477 2.61 ENSMUST00000040019.4
SRY-box containing gene 10
chrX_-_53240101 2.60 ENSMUST00000074861.2
placental specific protein 1
chr3_+_114030532 2.59 ENSMUST00000123619.1
ENSMUST00000092155.5
collagen, type XI, alpha 1
chr1_-_66935333 2.46 ENSMUST00000120415.1
ENSMUST00000119429.1
myosin, light polypeptide 1
chr6_+_30723541 2.45 ENSMUST00000115127.1
mesoderm specific transcript
chr6_+_41521782 2.45 ENSMUST00000070380.4
protease, serine, 2
chr4_-_88033328 2.40 ENSMUST00000078090.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_+_139210031 2.37 ENSMUST00000113043.1
ENSMUST00000169886.1
ENSMUST00000113045.2
melanoma associated antigen (mutated) 1-like 1
chr5_-_148392810 2.33 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_-_19851459 2.32 ENSMUST00000059805.4
solute carrier family 35, member D3
chr2_-_170406501 2.25 ENSMUST00000154650.1
breast carcinoma amplified sequence 1
chr7_-_30821139 2.23 ENSMUST00000163504.1
free fatty acid receptor 2
chr16_-_22161450 2.20 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr17_-_48432723 2.15 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr4_-_117125618 2.10 ENSMUST00000183310.1
BTB (POZ) domain containing 19
chr12_-_40248073 2.07 ENSMUST00000169926.1
interferon-related developmental regulator 1
chr1_+_107535508 2.05 ENSMUST00000182198.1
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr6_-_41035501 2.01 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr15_-_66801577 2.00 ENSMUST00000168589.1
src-like adaptor
chr9_-_39604124 2.00 ENSMUST00000042485.4
ENSMUST00000141370.1
expressed sequence AW551984
chr7_+_99535439 1.90 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr2_+_35282380 1.89 ENSMUST00000028239.6
gelsolin
chr6_-_142804390 1.87 ENSMUST00000111768.1
predicted gene 766
chr9_+_124102110 1.85 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr4_-_49593875 1.85 ENSMUST00000151542.1
transmembrane protein 246
chr10_+_115817247 1.84 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr15_-_34356421 1.82 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chrX_-_133688978 1.69 ENSMUST00000149154.1
ENSMUST00000167944.1
protocadherin 19
chrX_-_9469288 1.64 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr10_-_19014549 1.60 ENSMUST00000146388.1
tumor necrosis factor, alpha-induced protein 3
chrX_+_159627534 1.59 ENSMUST00000073094.3
SH3-domain kinase binding protein 1
chr3_+_146150174 1.56 ENSMUST00000098524.4
mucolipin 2
chr1_-_167466780 1.56 ENSMUST00000036643.4
leucine rich repeat containing 52
chr5_-_44099220 1.55 ENSMUST00000165909.1
prominin 1
chr11_-_100261021 1.53 ENSMUST00000080893.6
keratin 17
chr5_+_108369858 1.53 ENSMUST00000100944.2
predicted gene 10419
chr4_-_126325672 1.51 ENSMUST00000102616.1
tektin 2
chr9_+_124101944 1.47 ENSMUST00000171719.1
chemokine (C-C motif) receptor 2
chr11_+_29463735 1.46 ENSMUST00000155854.1
coiled coil domain containing 88A
chr7_-_134232125 1.44 ENSMUST00000127524.1
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr13_+_83504032 1.41 ENSMUST00000163888.1
ENSMUST00000005722.7
myocyte enhancer factor 2C
chr13_+_91461050 1.41 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr4_-_126325641 1.40 ENSMUST00000131113.1
tektin 2
chr5_+_13399309 1.38 ENSMUST00000030714.7
ENSMUST00000141968.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_166344692 1.36 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
glycoprotein m6b
chr3_-_106219477 1.35 ENSMUST00000082219.5
chitinase 3-like 4
chr6_-_82774448 1.35 ENSMUST00000000642.4
hexokinase 2
chr11_+_44617310 1.31 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
early B cell factor 1
chr8_+_45885479 1.31 ENSMUST00000034053.5
PDZ and LIM domain 3
chr11_-_79530569 1.31 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr18_+_64254359 1.30 ENSMUST00000025477.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr5_-_89883321 1.30 ENSMUST00000163159.1
ENSMUST00000061427.5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
chr10_+_100488289 1.29 ENSMUST00000164751.1
centrosomal protein 290
chrX_-_51681856 1.29 ENSMUST00000114871.1
heparan sulfate 6-O-sulfotransferase 2
chr7_+_100494044 1.27 ENSMUST00000153287.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_+_78926720 1.25 ENSMUST00000089377.5
lectin, galactose binding, soluble 1
chr16_-_13986855 1.24 ENSMUST00000117803.1
interferon induced transmembrane protein 7
chrX_-_51681703 1.24 ENSMUST00000088172.5
heparan sulfate 6-O-sulfotransferase 2
chr13_-_100786402 1.23 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
cyclin B1
chr1_-_95667555 1.23 ENSMUST00000043336.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr3_-_67463828 1.22 ENSMUST00000058981.2
latexin
chr3_-_129755305 1.19 ENSMUST00000029653.2
epidermal growth factor
chr7_-_127137807 1.18 ENSMUST00000049931.5
sialophorin
chr7_+_100493795 1.16 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_-_170927567 1.16 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr7_+_118712516 1.16 ENSMUST00000106557.1
centriolar coiled coil protein 110
chr11_+_108682602 1.14 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
centrosomal protein 112
chr9_-_60511003 1.13 ENSMUST00000098660.3
thrombospondin, type I, domain containing 4
chr19_-_50678642 1.11 ENSMUST00000072685.6
ENSMUST00000164039.2
VPS10 domain receptor protein SORCS 1
chr7_+_140218258 1.10 ENSMUST00000084460.6
CD163 molecule-like 1
chr5_-_138207302 1.09 ENSMUST00000160126.1
predicted gene 454
chr11_-_76027726 1.09 ENSMUST00000021207.6
family with sequence similarity 101, member B
chrX_+_164162167 1.08 ENSMUST00000131543.1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr10_-_28986280 1.08 ENSMUST00000152363.1
ENSMUST00000015663.6
RIKEN cDNA 2310057J18 gene
chr1_-_120505084 1.07 ENSMUST00000027639.1
macrophage receptor with collagenous structure
chr11_+_120361506 1.07 ENSMUST00000026445.2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr3_+_146121655 1.06 ENSMUST00000039450.4
mucolipin 3
chr4_-_116405986 1.05 ENSMUST00000123072.1
ENSMUST00000144281.1
microtubule associated serine/threonine kinase 2
chrX_+_159627265 1.05 ENSMUST00000112456.2
SH3-domain kinase binding protein 1
chr1_+_134037490 1.05 ENSMUST00000162779.1
fibromodulin
chr3_+_88532314 1.04 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr15_-_56694525 1.04 ENSMUST00000050544.7
hyaluronan synthase 2
chr9_-_121792478 1.00 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr10_+_42860776 1.00 ENSMUST00000105494.1
sex comb on midleg-like 4 (Drosophila)
chr13_-_117025505 1.00 ENSMUST00000022239.6
poly (ADP-ribose) polymerase family, member 8
chr6_+_149309444 0.97 ENSMUST00000100765.4
RIKEN cDNA 2810474O19 gene
chr16_-_3718105 0.95 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr11_+_9191934 0.94 ENSMUST00000042740.6
ATP-binding cassette, sub-family A (ABC1), member 13
chr11_+_96282529 0.93 ENSMUST00000125410.1
homeobox B8
chr1_-_156204998 0.93 ENSMUST00000015628.3
family with sequence similarity 163, member A
chrX_-_164258186 0.93 ENSMUST00000112265.2
BMX non-receptor tyrosine kinase
chr11_+_32000496 0.92 ENSMUST00000093219.3
neuron specific gene family member 2
chr5_+_138229822 0.92 ENSMUST00000159798.1
ENSMUST00000159964.1
neurexophilin and PC-esterase domain family, member 5
chr18_+_37020097 0.91 ENSMUST00000047614.1
protocadherin alpha 2
chr2_+_74704615 0.91 ENSMUST00000151380.1
homeobox D8
chr10_+_42860348 0.89 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr1_-_170927540 0.88 ENSMUST00000162136.1
ENSMUST00000162887.1
Fc receptor-like A
chr6_-_28397999 0.87 ENSMUST00000035930.4
zinc finger protein 800
chr8_+_84970068 0.87 ENSMUST00000164807.1
peroxiredoxin 2
chr11_+_97415527 0.85 ENSMUST00000121799.1
Rho GTPase activating protein 23
chr6_+_149309391 0.85 ENSMUST00000130664.1
ENSMUST00000046689.6
RIKEN cDNA 2810474O19 gene
chrX_+_72987339 0.84 ENSMUST00000164800.1
ENSMUST00000114546.2
zinc finger protein 185
chr11_-_70656467 0.84 ENSMUST00000131642.1
predicted gene 12319
chr7_+_81523531 0.84 ENSMUST00000181903.1
RIKEN cDNA 2900076A07 gene
chr7_-_113347273 0.83 ENSMUST00000117577.1
BTB (POZ) domain containing 10
chr10_+_127048235 0.81 ENSMUST00000165764.1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr4_+_132351768 0.81 ENSMUST00000172202.1
predicted gene, 17300
chr18_-_13972617 0.81 ENSMUST00000025288.7
zinc finger protein 521
chr7_-_102477902 0.81 ENSMUST00000061482.5
olfactory receptor 543
chr3_+_95499273 0.81 ENSMUST00000015664.3
cathepsin K
chr15_+_6579841 0.81 ENSMUST00000090461.5
FYN binding protein
chr2_-_140671400 0.81 ENSMUST00000056760.3
fibronectin leucine rich transmembrane protein 3
chr2_+_155751117 0.80 ENSMUST00000029140.5
ENSMUST00000132608.1
protein C receptor, endothelial
chr7_+_28071230 0.80 ENSMUST00000138392.1
ENSMUST00000076648.7
Fc fragment of IgG binding protein
chr11_+_63133068 0.80 ENSMUST00000108700.1
peripheral myelin protein 22
chr7_+_75643223 0.79 ENSMUST00000137959.1
A kinase (PRKA) anchor protein 13
chr18_-_54990124 0.79 ENSMUST00000064763.5
zinc finger protein 608
chr4_-_133872304 0.78 ENSMUST00000157067.2
ribosomal protein S6 kinase polypeptide 1
chrX_+_123581700 0.78 ENSMUST00000178457.1
predicted gene 6604
chr14_+_52016849 0.77 ENSMUST00000100638.2
transmembrane protein 253
chr11_-_53618659 0.76 ENSMUST00000000889.6
interleukin 4
chr11_+_44400060 0.75 ENSMUST00000102796.3
ENSMUST00000170513.1
interleukin 12b
chr8_+_106510853 0.75 ENSMUST00000080797.6
cadherin 3
chr3_-_152266320 0.75 ENSMUST00000046045.8
nexilin
chr10_-_44458715 0.74 ENSMUST00000039174.4
PR domain containing 1, with ZNF domain
chr5_+_3543812 0.74 ENSMUST00000115527.3
family with sequence similarity 133, member B
chr1_-_23909687 0.74 ENSMUST00000129254.1
small ArfGAP 1
chr1_-_60043087 0.73 ENSMUST00000027172.6
islet cell autoantigen 1-like
chr11_+_63132569 0.73 ENSMUST00000108701.1
peripheral myelin protein 22
chr9_+_64385626 0.72 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
multiple EGF-like-domains 11
chr12_+_91400990 0.71 ENSMUST00000021346.7
ENSMUST00000021343.6
thyroid stimulating hormone receptor
chr15_-_83251720 0.71 ENSMUST00000164614.1
ENSMUST00000049530.6
alpha 1,4-galactosyltransferase
chr4_-_132351636 0.71 ENSMUST00000105951.1
regulator of chromosome condensation 1
chr11_-_99493112 0.71 ENSMUST00000006969.7
keratin 23
chr18_-_38250157 0.70 ENSMUST00000181871.1
RIKEN cDNA 1700086O06 gene
chr4_-_129558355 0.68 ENSMUST00000167288.1
ENSMUST00000134336.1
lymphocyte protein tyrosine kinase
chrX_-_105929397 0.68 ENSMUST00000113573.1
ENSMUST00000130980.1
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr19_+_10525244 0.68 ENSMUST00000038379.3
cleavage and polyadenylation specific factor 7
chr14_+_79515618 0.68 ENSMUST00000110835.1
E74-like factor 1
chr4_-_129558387 0.68 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr11_+_67200052 0.68 ENSMUST00000124516.1
ENSMUST00000018637.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr1_-_91459254 0.67 ENSMUST00000069620.8
period circadian clock 2
chrX_+_7822289 0.67 ENSMUST00000009875.4
potassium voltage-gated channel, Shal-related family, member 1
chr2_-_121271315 0.67 ENSMUST00000131245.1
transformation related protein 53 binding protein 1
chr10_+_67185730 0.67 ENSMUST00000173689.1
jumonji domain containing 1C
chr8_+_19682268 0.66 ENSMUST00000153710.1
ENSMUST00000127799.1
predicted gene 6483
chrX_+_103422010 0.65 ENSMUST00000182089.1
predicted gene, 26992
chr4_-_11386679 0.65 ENSMUST00000043781.7
ENSMUST00000108310.1
epithelial splicing regulatory protein 1
chr3_+_14533788 0.64 ENSMUST00000108370.2
leucine rich repeat and coiled-coil domain containing 1
chr2_-_73529725 0.64 ENSMUST00000094681.4
WAS/WASL interacting protein family, member 1
chr8_-_69791170 0.64 ENSMUST00000131784.1
zinc finger protein 866
chr15_+_61985540 0.64 ENSMUST00000159327.1
ENSMUST00000167731.1
myelocytomatosis oncogene
chr13_+_93304940 0.64 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
homer homolog 1 (Drosophila)
chr10_-_62507737 0.63 ENSMUST00000020271.6
serglycin
chr10_-_44458687 0.63 ENSMUST00000105490.2
PR domain containing 1, with ZNF domain
chr1_+_21272338 0.63 ENSMUST00000178379.1
predicted pseudogene 7094
chr2_-_124222331 0.63 ENSMUST00000136658.1
RIKEN cDNA 4930583P06 gene
chr7_+_81523555 0.62 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
RIKEN cDNA 2900076A07 gene
chr3_-_61365951 0.62 ENSMUST00000066298.2
RIKEN cDNA B430305J03 gene
chr19_-_5845471 0.62 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr3_+_14533817 0.62 ENSMUST00000169079.1
ENSMUST00000091325.3
leucine rich repeat and coiled-coil domain containing 1
chr12_+_58211772 0.61 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr18_-_10181792 0.61 ENSMUST00000067947.5
Rho-associated coiled-coil containing protein kinase 1
chr5_+_35893319 0.61 ENSMUST00000064571.4
actin filament associated protein 1
chr15_-_100424208 0.61 ENSMUST00000154331.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr13_+_44731281 0.59 ENSMUST00000174086.1
jumonji, AT rich interactive domain 2
chr17_+_78508063 0.59 ENSMUST00000024880.9
vitrin
chr4_+_130047840 0.59 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr8_-_104624266 0.58 ENSMUST00000163783.2
cadherin 16
chr14_+_53795455 0.58 ENSMUST00000103671.2
RIKEN cDNA B230359F08 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:1990535 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
1.5 4.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.2 1.2 GO:0032053 ciliary basal body organization(GO:0032053)
1.1 3.3 GO:2000458 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.8 2.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.8 4.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.7 2.2 GO:0002879 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.7 3.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.7 0.7 GO:0001575 globoside metabolic process(GO:0001575)
0.6 1.9 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.6 5.7 GO:0032264 IMP salvage(GO:0032264)
0.5 1.6 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.5 1.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.5 1.4 GO:0007521 muscle cell fate determination(GO:0007521)
0.5 1.4 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.4 2.6 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.4 2.6 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.4 2.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 1.2 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.4 1.2 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
0.4 2.6 GO:0035989 tendon development(GO:0035989)
0.3 1.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 1.3 GO:1990743 protein sialylation(GO:1990743)
0.3 1.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.3 1.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 2.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 1.1 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 1.4 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 2.7 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.3 1.1 GO:0035128 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.3 0.8 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.3 1.0 GO:1903059 regulation of protein lipidation(GO:1903059)
0.2 0.9 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.2 0.5 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.2 0.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 1.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 2.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 1.6 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 0.6 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.2 2.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.8 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.2 1.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2 0.7 GO:0051794 regulation of catagen(GO:0051794)
0.2 1.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.2 2.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.6 GO:0090096 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 0.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 0.6 GO:0033380 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 2.4 GO:0031000 response to caffeine(GO:0031000)
0.2 0.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 6.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:0010912 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 2.3 GO:0015809 arginine transport(GO:0015809)
0.1 2.0 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 2.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 3.0 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.7 GO:1904587 response to glycoprotein(GO:1904587)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 1.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.9 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 2.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 1.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.5 GO:0032060 bleb assembly(GO:0032060)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.2 GO:0014060 regulation of epinephrine secretion(GO:0014060)
0.1 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 1.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 1.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.2 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:0061235 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.3 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.5 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 4.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.5 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.8 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0019660 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.6 GO:0030575 nuclear body organization(GO:0030575)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 1.3 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.7 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 1.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 2.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.9 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0021591 ventricular system development(GO:0021591)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.4 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) somatotropin secreting cell differentiation(GO:0060126)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 1.5 GO:0071914 prominosome(GO:0071914)
0.3 1.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 1.5 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.1 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 4.8 GO:0031143 pseudopodium(GO:0031143)
0.2 1.9 GO:0030478 actin cap(GO:0030478)
0.2 5.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 2.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 2.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.7 GO:0061574 ASAP complex(GO:0061574)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 1.5 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 2.8 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0031672 A band(GO:0031672)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0045159 myosin II binding(GO:0045159)
1.5 4.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.1 3.3 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.6 2.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.6 5.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 2.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 1.2 GO:0048030 disaccharide binding(GO:0048030)
0.4 2.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 2.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 1.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 1.5 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 2.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 2.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 0.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 6.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 1.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.1 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.4 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 4.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.6 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 2.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 6.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 2.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 6.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.1 6.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 5.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.1 REACTOME DEFENSINS Genes involved in Defensins
0.2 1.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 5.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 3.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 3.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 4.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription