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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nkx2-2

Z-value: 1.27

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Transcription factors associated with Nkx2-2

Gene Symbol Gene ID Gene Info
Nkx2-2
ENSMUSG00000027434.10 NK2 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-2mm10_v2_chr2_-_147186389_147186413-0.134.6e-01Click!

Activity profile of Nkx2-2 motif

Sorted Z-values of Nkx2-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_46039202 7.62 ENSMUST00000156200.1
Tmod1
tropomodulin 1
chr10_+_88091070 6.76 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr6_-_41704339 6.57 ENSMUST00000031899.8
Kel
Kell blood group
chr9_+_72438519 5.70 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr9_+_72438534 5.36 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chrX_+_9885622 5.04 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5
synaptotagmin-like 5
chr6_+_86078070 4.67 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr1_+_40439767 4.45 ENSMUST00000173514.1
Il1rl1
interleukin 1 receptor-like 1
chr1_+_40439627 4.26 ENSMUST00000097772.3
Il1rl1
interleukin 1 receptor-like 1
chr1_-_52953179 3.87 ENSMUST00000114492.1
1700019D03Rik
RIKEN cDNA 1700019D03 gene
chr13_-_19824234 3.49 ENSMUST00000065335.2
Gpr141
G protein-coupled receptor 141
chr7_+_103915062 3.44 ENSMUST00000059011.3
ENSMUST00000167269.1
Olfr631
olfactory receptor 631
chr6_+_5390387 3.36 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr2_+_174450678 3.35 ENSMUST00000016399.5
Tubb1
tubulin, beta 1 class VI
chr7_+_110772604 3.29 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr6_-_102464667 2.88 ENSMUST00000032159.6
Cntn3
contactin 3
chr11_+_78301529 2.83 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr1_-_176807124 2.80 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr15_-_75111684 2.75 ENSMUST00000100542.3
Ly6c2
lymphocyte antigen 6 complex, locus C2
chrX_+_106027259 2.53 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_140170528 2.50 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr18_-_62179948 2.44 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr6_-_70792155 2.34 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr19_+_55180799 2.30 ENSMUST00000025936.5
Tectb
tectorin beta
chr14_+_53795455 2.19 ENSMUST00000103671.2
B230359F08Rik
RIKEN cDNA B230359F08 gene
chr1_-_65123108 2.12 ENSMUST00000050047.3
ENSMUST00000148020.1
D630023F18Rik
RIKEN cDNA D630023F18 gene
chr18_+_4993795 2.09 ENSMUST00000153016.1
Svil
supervillin
chr6_-_136857727 2.07 ENSMUST00000032341.2
Art4
ADP-ribosyltransferase 4
chrX_+_106027300 2.04 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr6_-_136401830 2.02 ENSMUST00000058713.7
E330021D16Rik
RIKEN cDNA E330021D16 gene
chr13_+_23756937 1.93 ENSMUST00000102965.2
Hist1h4b
histone cluster 1, H4b
chr15_+_66670749 1.92 ENSMUST00000065916.7
Tg
thyroglobulin
chr13_-_21753851 1.89 ENSMUST00000074752.2
Hist1h2ak
histone cluster 1, H2ak
chr7_-_100855403 1.88 ENSMUST00000156855.1
Relt
RELT tumor necrosis factor receptor
chr17_+_48346465 1.85 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr17_+_17887840 1.85 ENSMUST00000054871.5
ENSMUST00000064068.4
Fpr3
Fpr2
formyl peptide receptor 3
formyl peptide receptor 2
chr9_-_96719404 1.81 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr17_+_43568641 1.75 ENSMUST00000169694.1
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_+_43568475 1.75 ENSMUST00000167418.1
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chrX_+_164980592 1.73 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fancb
Fanconi anemia, complementation group B
chr5_-_123140135 1.71 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr8_+_123332676 1.70 ENSMUST00000010298.6
Spire2
spire homolog 2 (Drosophila)
chr6_+_8520008 1.62 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1
glucocorticoid induced transcript 1
chr6_-_120357342 1.61 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr3_+_108739658 1.58 ENSMUST00000133931.2
Aknad1
AKNA domain containing 1
chr14_-_55788810 1.54 ENSMUST00000022830.6
ENSMUST00000168716.1
ENSMUST00000178399.1
Ripk3
receptor-interacting serine-threonine kinase 3
chr7_-_43533171 1.52 ENSMUST00000004728.5
ENSMUST00000039861.5
Cd33
CD33 antigen
chr14_-_104522615 1.48 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr19_-_5796924 1.47 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr9_+_51213683 1.45 ENSMUST00000034554.7
Pou2af1
POU domain, class 2, associating factor 1
chr14_+_47663756 1.44 ENSMUST00000022391.7
Ktn1
kinectin 1
chrX_+_142825698 1.44 ENSMUST00000112888.1
Tmem164
transmembrane protein 164
chrX_+_101274023 1.43 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr2_+_52072823 1.41 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1
Rap1 interacting factor 1 homolog (yeast)
chr9_+_3017408 1.40 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr6_-_56369625 1.40 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c
phosphodiesterase 1C
chr8_+_41239718 1.39 ENSMUST00000045218.7
Pcm1
pericentriolar material 1
chr2_+_174076296 1.38 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
Stx16
syntaxin 16
chr13_-_8858762 1.37 ENSMUST00000176329.1
Wdr37
WD repeat domain 37
chrX_+_75382384 1.36 ENSMUST00000033541.4
Fundc2
FUN14 domain containing 2
chr13_+_104178797 1.36 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23
tripartite motif-containing 23
chr5_+_10236829 1.33 ENSMUST00000101606.3
Gm10482
predicted gene 10482
chr19_-_37178011 1.32 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr12_+_55089202 1.32 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr6_-_120357440 1.30 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr13_+_24614608 1.30 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr2_+_83644435 1.29 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr3_-_93015669 1.29 ENSMUST00000107301.1
ENSMUST00000029521.4
Crct1
cysteine-rich C-terminal 1
chr2_+_62664279 1.29 ENSMUST00000028257.2
Gca
grancalcin
chr10_+_14523062 1.28 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr8_-_24948771 1.23 ENSMUST00000119720.1
ENSMUST00000121438.2
Adam32
a disintegrin and metallopeptidase domain 32
chr3_-_59220150 1.22 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr6_-_120357422 1.22 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr1_-_85736525 1.21 ENSMUST00000064788.7
A630001G21Rik
RIKEN cDNA A630001G21 gene
chr11_-_79523760 1.19 ENSMUST00000179322.1
Evi2b
ecotropic viral integration site 2b
chr18_+_82554463 1.19 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp
myelin basic protein
chr9_+_3005125 1.19 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr10_-_93891141 1.18 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chr2_-_73453918 1.18 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr15_-_10470490 1.12 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr3_+_14533817 1.10 ENSMUST00000169079.1
ENSMUST00000091325.3
Lrrcc1
leucine rich repeat and coiled-coil domain containing 1
chr11_+_48800357 1.10 ENSMUST00000020640.7
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr5_+_110839973 1.10 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr15_-_73184840 1.09 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chr6_+_29859686 1.08 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr5_-_69592274 1.08 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2
glucosamine-6-phosphate deaminase 2
chr5_-_30073554 1.08 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr1_-_152386589 1.06 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr8_+_69300776 1.06 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr14_-_19418930 1.05 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr3_+_65528457 1.02 ENSMUST00000130705.1
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr3_+_5218516 1.02 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr17_+_71019548 1.01 ENSMUST00000073211.5
ENSMUST00000179759.1
Myom1
myomesin 1
chr19_-_40402267 0.99 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1
sorbin and SH3 domain containing 1
chr11_-_26591729 0.99 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr14_-_54686060 0.99 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr1_+_179961110 0.99 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa
CDC42 binding protein kinase alpha
chr9_+_3034599 0.98 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr19_-_29753600 0.97 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr14_-_72602945 0.97 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr2_-_58160495 0.97 ENSMUST00000028175.6
Cytip
cytohesin 1 interacting protein
chr5_-_110839575 0.95 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr3_-_130730375 0.95 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr8_+_123411424 0.94 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr10_+_57645834 0.94 ENSMUST00000177325.1
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr9_+_35559460 0.94 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3
pseudouridine synthase 3
chr9_+_3025417 0.91 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr11_+_3649759 0.90 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr13_+_38036989 0.87 ENSMUST00000021866.8
Riok1
RIO kinase 1 (yeast)
chr18_-_6241470 0.87 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr10_+_57645861 0.86 ENSMUST00000177473.1
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr5_+_149439706 0.85 ENSMUST00000031667.4
Tex26
testis expressed 26
chr2_+_69897255 0.84 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_77946375 0.84 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr2_-_25095125 0.84 ENSMUST00000114373.1
Noxa1
NADPH oxidase activator 1
chr5_+_66968961 0.83 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr2_-_77946331 0.83 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr9_+_3015654 0.82 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr1_-_166002613 0.80 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1
POU domain, class 2, transcription factor 1
chr3_+_10366903 0.79 ENSMUST00000029049.5
Chmp4c
charged multivesicular body protein 4C
chr9_+_3018753 0.77 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr2_+_43748802 0.76 ENSMUST00000112824.1
ENSMUST00000055776.7
Arhgap15
Rho GTPase activating protein 15
chr2_-_25095149 0.75 ENSMUST00000044018.7
Noxa1
NADPH oxidase activator 1
chr1_-_152386675 0.74 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr13_-_103764502 0.74 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr17_-_65884902 0.74 ENSMUST00000024905.9
Ralbp1
ralA binding protein 1
chr4_+_155891822 0.74 ENSMUST00000105584.3
ENSMUST00000079031.5
Acap3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr4_+_59626189 0.73 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik
RIKEN cDNA E130308A19 gene
chr4_+_126024506 0.73 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chrX_+_68821093 0.70 ENSMUST00000096420.2
Gm14698
predicted gene 14698
chr12_+_38781093 0.69 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr12_+_107488632 0.68 ENSMUST00000082269.2
3110018I06Rik
RIKEN cDNA 3110018I06 gene
chr14_+_24490678 0.67 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24
ribosomal protein S24
chr16_-_16527364 0.67 ENSMUST00000069284.7
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr4_-_129640959 0.65 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna
taxilin alpha
chr4_-_45532470 0.64 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr17_+_71616215 0.62 ENSMUST00000047086.9
Wdr43
WD repeat domain 43
chr5_+_66968559 0.62 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr14_-_73049107 0.62 ENSMUST00000044664.4
ENSMUST00000169168.1
Cysltr2
cysteinyl leukotriene receptor 2
chr14_+_103513328 0.61 ENSMUST00000095576.3
Scel
sciellin
chr8_-_36953139 0.61 ENSMUST00000179501.1
Dlc1
deleted in liver cancer 1
chr16_+_14580221 0.61 ENSMUST00000147024.1
A630010A05Rik
RIKEN cDNA A630010A05 gene
chr5_-_110839757 0.61 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr3_+_65528404 0.59 ENSMUST00000047906.3
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr2_+_91650116 0.58 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr17_+_78882003 0.57 ENSMUST00000180880.1
Gm26637
predicted gene, 26637
chr3_+_3634145 0.56 ENSMUST00000108394.1
Hnf4g
hepatocyte nuclear factor 4, gamma
chr1_+_86064619 0.56 ENSMUST00000027432.8
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr12_-_112860886 0.55 ENSMUST00000021729.7
Gpr132
G protein-coupled receptor 132
chr11_-_69900930 0.54 ENSMUST00000018714.6
ENSMUST00000128046.1
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr5_+_87925579 0.54 ENSMUST00000001667.6
ENSMUST00000113267.1
Csn3
casein kappa
chr9_-_96719549 0.53 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr17_-_32822200 0.52 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr18_+_12972225 0.51 ENSMUST00000025290.5
Impact
imprinted and ancient
chr13_-_38036923 0.50 ENSMUST00000110233.1
ENSMUST00000074969.4
ENSMUST00000131066.1
Cage1
cancer antigen 1
chr1_-_135688094 0.50 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr1_+_179960472 0.50 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr3_+_138143888 0.50 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr16_+_32496259 0.50 ENSMUST00000064192.7
Zdhhc19
zinc finger, DHHC domain containing 19
chr12_-_83487708 0.50 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3
D4, zinc and double PHD fingers, family 3
chr11_-_69900949 0.49 ENSMUST00000102580.3
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr3_-_30140407 0.49 ENSMUST00000108271.3
Mecom
MDS1 and EVI1 complex locus
chr6_+_88465409 0.49 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr8_+_105880875 0.49 ENSMUST00000040254.9
ENSMUST00000119261.1
Edc4
enhancer of mRNA decapping 4
chr11_-_71004387 0.48 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chrM_+_11734 0.47 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr12_-_83984849 0.47 ENSMUST00000164935.2
Gm17673
predicted gene, 17673
chr3_+_138143429 0.46 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr7_-_123369870 0.45 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
Arhgap17
Rho GTPase activating protein 17
chr10_-_13388830 0.45 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chrX_+_107149580 0.45 ENSMUST00000137107.1
ENSMUST00000067249.2
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr19_+_8819401 0.45 ENSMUST00000096753.3
Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr6_+_143285988 0.45 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr2_+_163661495 0.44 ENSMUST00000135537.1
Pkig
protein kinase inhibitor, gamma
chr19_+_34100943 0.44 ENSMUST00000025685.6
Lipm
lipase, family member M
chr12_+_73901370 0.43 ENSMUST00000110461.1
Hif1a
hypoxia inducible factor 1, alpha subunit
chr11_+_66956620 0.42 ENSMUST00000150220.1
9130409J20Rik
RIKEN cDNA 9130409J20 gene
chr15_-_102350692 0.41 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr2_+_3704787 0.41 ENSMUST00000115054.2
Fam107b
family with sequence similarity 107, member B
chr18_-_6241486 0.41 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr3_-_92687209 0.40 ENSMUST00000029524.3
Lce1d
late cornified envelope 1D
chr4_-_43010226 0.39 ENSMUST00000030165.4
Fancg
Fanconi anemia, complementation group G
chr3_+_32515295 0.38 ENSMUST00000029203.7
Zfp639
zinc finger protein 639
chr10_-_116896879 0.38 ENSMUST00000048229.7
Myrfl
myelin regulatory factor-like
chrX_+_6415736 0.38 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr1_-_9748376 0.38 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chrX_+_107149454 0.37 ENSMUST00000125676.1
ENSMUST00000180182.1
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr11_-_69900886 0.37 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr6_+_122990367 0.36 ENSMUST00000079379.2
Clec4a4
C-type lectin domain family 4, member a4
chr5_-_3596071 0.36 ENSMUST00000121877.1
Rbm48
RNA binding motif protein 48
chr19_+_58759700 0.36 ENSMUST00000026081.3
Pnliprp2
pancreatic lipase-related protein 2
chr6_-_23650206 0.35 ENSMUST00000115354.1
Rnf133
ring finger protein 133
chr8_+_40354303 0.35 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr2_+_71873224 0.35 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr3_+_138143483 0.35 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr11_+_99785191 0.35 ENSMUST00000105059.2
Krtap4-9
keratin associated protein 4-9
chr3_+_138143846 0.34 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr2_+_91650169 0.34 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr9_-_4796218 0.33 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
chr3_-_106024911 0.33 ENSMUST00000066537.3
ENSMUST00000054973.3
Chi3l7
chitinase 3-like 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
1.5 4.6 GO:1904732 elastin biosynthetic process(GO:0051542) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
1.3 7.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.1 6.6 GO:0031133 regulation of axon diameter(GO:0031133)
0.8 8.7 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.7 2.8 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.6 1.9 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.6 2.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.6 2.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.6 3.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.6 11.1 GO:0070986 left/right axis specification(GO:0070986)
0.6 1.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.5 1.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.4 1.3 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.4 1.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.4 1.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.4 1.5 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.4 3.3 GO:0032264 IMP salvage(GO:0032264)
0.4 1.1 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.3 3.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 1.2 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 1.5 GO:0035063 nuclear speck organization(GO:0035063)
0.3 1.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.1 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.3 0.8 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.3 1.3 GO:0072383 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.5 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 1.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 1.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 0.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 1.9 GO:0015705 iodide transport(GO:0015705)
0.2 4.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 0.5 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.9 GO:0032439 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 2.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.7 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 5.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 5.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 1.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.6 GO:0060263 regulation of respiratory burst(GO:0060263)
0.1 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.2 GO:0071963 unidimensional cell growth(GO:0009826) establishment or maintenance of cell polarity regulating cell shape(GO:0071963) regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.7 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.3 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 1.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.5 GO:0000492 box C/D snoRNP assembly(GO:0000492) positive regulation of plasminogen activation(GO:0010756)
0.1 1.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 3.3 GO:0051225 spindle assembly(GO:0051225)
0.0 1.0 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.9 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 3.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 2.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.3 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 2.2 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.5 3.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.5 GO:0097342 ripoptosome(GO:0097342)
0.2 2.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 0.9 GO:0097443 sorting endosome(GO:0097443)
0.2 1.4 GO:0001940 male pronucleus(GO:0001940)
0.2 1.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 3.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 7.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 2.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0033269 internode region of axon(GO:0033269)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 4.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.1 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.0 GO:0061574 ASAP complex(GO:0061574)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 11.1 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 1.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.6 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 8.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 1.6 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0016460 myosin II complex(GO:0016460)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 8.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 2.0 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 3.5 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 4.4 GO:0005874 microtubule(GO:0005874)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 5.2 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0002113 interleukin-33 binding(GO:0002113)
1.1 4.6 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.6 2.4 GO:0031711 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.4 7.6 GO:0005523 tropomyosin binding(GO:0005523)
0.4 3.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 3.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.3 3.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 1.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 1.8 GO:0005124 scavenger receptor binding(GO:0005124)
0.3 1.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 1.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 1.8 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 1.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 1.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 5.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.6 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 3.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 2.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 5.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 5.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 6.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0000182 rDNA binding(GO:0000182)
0.0 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 3.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)
0.0 1.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 2.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.0 4.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.9 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.4 PID ATM PATHWAY ATM pathway
0.0 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID IGF1 PATHWAY IGF1 pathway
0.0 1.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 3.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 7.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 4.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 7.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock