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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nkx2-9

Z-value: 0.80

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Transcription factors associated with Nkx2-9

Gene Symbol Gene ID Gene Info
Nkx2-9
ENSMUSG00000058669.7 NK2 homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-9mm10_v2_chr12_-_56613270_566132910.029.1e-01Click!

Activity profile of Nkx2-9 motif

Sorted Z-values of Nkx2-9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_98490522 4.87 ENSMUST00000035029.2
Rbp2
retinol binding protein 2, cellular
chr6_-_40999479 4.32 ENSMUST00000166306.1
Gm2663
predicted gene 2663
chr6_+_41354105 3.90 ENSMUST00000072103.5
Try10
trypsin 10
chr6_+_78370877 3.55 ENSMUST00000096904.3
Reg3b
regenerating islet-derived 3 beta
chr7_-_142576492 3.51 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr4_-_119189949 3.47 ENSMUST00000124626.1
Ermap
erythroblast membrane-associated protein
chr2_+_173022360 3.00 ENSMUST00000173997.1
Rbm38
RNA binding motif protein 38
chr6_-_78378851 2.83 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d
regenerating islet-derived 3 delta
chr4_-_119190005 2.16 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap
erythroblast membrane-associated protein
chr6_+_145121727 1.92 ENSMUST00000032396.6
Lrmp
lymphoid-restricted membrane protein
chrX_+_135993820 1.83 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr2_+_103969528 1.65 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2
LIM domain only 2
chr15_-_79285502 1.61 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr4_+_34893772 1.61 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
Cga
glycoprotein hormones, alpha subunit
chr10_+_21690845 1.51 ENSMUST00000071008.3
Gm5420
predicted gene 5420
chr7_+_30422389 1.44 ENSMUST00000108175.1
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr6_-_78468863 1.42 ENSMUST00000032089.2
Reg3g
regenerating islet-derived 3 gamma
chr12_-_114416895 1.40 ENSMUST00000179796.1
Ighv6-5
immunoglobulin heavy variable V6-5
chr11_+_117849223 1.39 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chrX_-_49788204 1.37 ENSMUST00000114893.1
Igsf1
immunoglobulin superfamily, member 1
chr9_+_57504012 1.31 ENSMUST00000080514.7
Rpp25
ribonuclease P/MRP 25 subunit
chr9_-_75683992 1.31 ENSMUST00000034699.6
Scg3
secretogranin III
chr10_-_86732409 1.31 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr3_+_96670131 1.26 ENSMUST00000048427.5
Ankrd35
ankyrin repeat domain 35
chr11_+_117849286 1.05 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr6_-_113434529 1.00 ENSMUST00000133348.1
Cidec
cell death-inducing DFFA-like effector c
chr4_-_138757578 0.91 ENSMUST00000030526.6
Pla2g2f
phospholipase A2, group IIF
chr6_+_78380700 0.88 ENSMUST00000101272.1
Reg3a
regenerating islet-derived 3 alpha
chr14_+_77156733 0.78 ENSMUST00000022589.7
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr3_-_59101810 0.78 ENSMUST00000085040.4
Gpr171
G protein-coupled receptor 171
chr6_+_135362931 0.77 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr17_+_32403006 0.75 ENSMUST00000065921.5
A530088E08Rik
RIKEN cDNA A530088E08 gene
chr11_-_99493112 0.73 ENSMUST00000006969.7
Krt23
keratin 23
chr1_-_181842334 0.72 ENSMUST00000005003.6
Lbr
lamin B receptor
chr13_-_51567084 0.72 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr9_-_58741543 0.72 ENSMUST00000098674.4
2410076I21Rik
RIKEN cDNA 2410076I21 gene
chr18_-_35662180 0.71 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24
spermatogenesis associated 24
chr6_-_142507805 0.68 ENSMUST00000134191.1
ENSMUST00000032373.5
Ldhb
lactate dehydrogenase B
chr6_-_136401830 0.68 ENSMUST00000058713.7
E330021D16Rik
RIKEN cDNA E330021D16 gene
chr10_+_88091070 0.66 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr4_+_141420757 0.64 ENSMUST00000102486.4
Hspb7
heat shock protein family, member 7 (cardiovascular)
chr8_+_94377911 0.63 ENSMUST00000159142.1
Gm15889
predicted gene 15889
chr1_-_120505084 0.63 ENSMUST00000027639.1
Marco
macrophage receptor with collagenous structure
chr1_+_63176818 0.59 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chrX_+_56779437 0.55 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chrX_+_13632769 0.55 ENSMUST00000096492.3
Gpr34
G protein-coupled receptor 34
chr2_-_152398046 0.49 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12
SRY-box containing gene 12
chr18_-_65393844 0.48 ENSMUST00000035548.8
Alpk2
alpha-kinase 2
chr15_-_98777261 0.48 ENSMUST00000166022.1
Wnt10b
wingless related MMTV integration site 10b
chr10_+_68723723 0.47 ENSMUST00000080995.6
Tmem26
transmembrane protein 26
chr1_+_74153981 0.46 ENSMUST00000027372.7
ENSMUST00000106899.2
Cxcr2
chemokine (C-X-C motif) receptor 2
chr10_+_14523062 0.46 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr17_-_51833278 0.46 ENSMUST00000133574.1
Satb1
special AT-rich sequence binding protein 1
chr9_-_56161051 0.45 ENSMUST00000034876.8
Tspan3
tetraspanin 3
chr12_-_24493656 0.45 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chrX_-_102189371 0.45 ENSMUST00000033683.7
Rps4x
ribosomal protein S4, X-linked
chr8_+_95703037 0.44 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4
N-myc downstream regulated gene 4
chr15_+_79690869 0.43 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr8_+_95633500 0.40 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr12_+_69790288 0.39 ENSMUST00000021378.3
4930512B01Rik
RIKEN cDNA 4930512B01 gene
chr7_+_30280094 0.36 ENSMUST00000108187.1
ENSMUST00000014072.5
Thap8
THAP domain containing 8
chr15_-_78204228 0.36 ENSMUST00000005860.9
Pvalb
parvalbumin
chrX_-_6320717 0.35 ENSMUST00000024049.7
Bmp15
bone morphogenetic protein 15
chr3_+_37348645 0.35 ENSMUST00000038885.3
Fgf2
fibroblast growth factor 2
chr2_+_80638798 0.35 ENSMUST00000028382.6
ENSMUST00000124377.1
Nup35
nucleoporin 35
chr5_+_147430407 0.33 ENSMUST00000176600.1
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr11_-_106788845 0.33 ENSMUST00000123339.1
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr6_+_35177610 0.32 ENSMUST00000170234.1
Nup205
nucleoporin 205
chr14_+_75455957 0.31 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr4_+_155891822 0.31 ENSMUST00000105584.3
ENSMUST00000079031.5
Acap3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr11_-_106789157 0.30 ENSMUST00000129585.1
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr11_+_114668524 0.30 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38
ribosomal protein L38
chr3_-_89245159 0.29 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr4_-_41275091 0.29 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2
ubiquitin-associated protein 2
chr7_+_4925802 0.27 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chrX_-_95658392 0.25 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr6_+_35177386 0.25 ENSMUST00000043815.9
Nup205
nucleoporin 205
chr9_-_107770945 0.24 ENSMUST00000183248.1
ENSMUST00000182022.1
ENSMUST00000035199.6
ENSMUST00000182659.1
Rbm5
RNA binding motif protein 5
chr16_-_33380717 0.23 ENSMUST00000180923.1
1700007L15Rik
RIKEN cDNA 1700007L15 gene
chr1_-_135688094 0.23 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr7_-_104390586 0.22 ENSMUST00000106828.1
Trim30c
tripartite motif-containing 30C
chr4_-_72852622 0.22 ENSMUST00000179234.1
ENSMUST00000078617.4
Aldoart1
aldolase 1 A, retrogene 1
chr16_+_36694024 0.22 ENSMUST00000119464.1
Ildr1
immunoglobulin-like domain containing receptor 1
chr1_-_128103016 0.22 ENSMUST00000097597.2
Zranb3
zinc finger, RAN-binding domain containing 3
chr16_+_36693972 0.21 ENSMUST00000023617.6
ENSMUST00000089618.3
Ildr1
immunoglobulin-like domain containing receptor 1
chr3_+_37420273 0.21 ENSMUST00000029277.8
Spata5
spermatogenesis associated 5
chr11_-_106788486 0.20 ENSMUST00000021062.5
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr18_-_60848911 0.20 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1
Treacher Collins Franceschetti syndrome 1, homolog
chr4_-_132884509 0.20 ENSMUST00000030698.4
Stx12
syntaxin 12
chr5_+_141856692 0.19 ENSMUST00000074546.6
Sdk1
sidekick homolog 1 (chicken)
chr1_+_9545397 0.19 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr13_+_109260481 0.19 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr8_+_95320440 0.19 ENSMUST00000162294.1
Tepp
testis, prostate and placenta expressed
chr12_+_71136848 0.18 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chrX_-_95658379 0.18 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr8_-_80880479 0.17 ENSMUST00000034150.8
Gab1
growth factor receptor bound protein 2-associated protein 1
chr4_-_141664063 0.16 ENSMUST00000084203.4
Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr6_-_34977999 0.16 ENSMUST00000044387.7
2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr6_-_6217023 0.16 ENSMUST00000015256.8
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr17_-_25861456 0.15 ENSMUST00000079461.8
ENSMUST00000176923.1
Wdr90
WD repeat domain 90
chr2_-_26910569 0.14 ENSMUST00000015920.5
ENSMUST00000139815.1
ENSMUST00000102899.3
Med22
mediator complex subunit 22
chr13_-_71963713 0.14 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chrX_+_42149288 0.13 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2
stromal antigen 2
chr7_-_102018139 0.13 ENSMUST00000094134.3
Il18bp
interleukin 18 binding protein
chr2_-_33130565 0.12 ENSMUST00000124000.1
Garnl3
GTPase activating RANGAP domain-like 3
chr11_+_106789235 0.12 ENSMUST00000103068.3
ENSMUST00000018516.4
Cep95
centrosomal protein 95
chr1_-_74600564 0.12 ENSMUST00000127938.1
ENSMUST00000154874.1
Rnf25
ring finger protein 25
chr3_-_89245005 0.12 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr15_+_100469034 0.10 ENSMUST00000037001.8
Letmd1
LETM1 domain containing 1
chr9_-_106887000 0.10 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr11_+_70029742 0.09 ENSMUST00000132597.2
Dlg4
discs, large homolog 4 (Drosophila)
chrX_-_95658416 0.08 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr1_+_128103297 0.08 ENSMUST00000036288.4
R3hdm1
R3H domain containing 1
chr1_-_23102243 0.07 ENSMUST00000073179.5
4933415F23Rik
RIKEN cDNA 4933415F23 gene
chr11_-_109363654 0.07 ENSMUST00000070956.3
Gm11696
predicted gene 11696
chr11_-_96747405 0.06 ENSMUST00000180492.1
2010300F17Rik
RIKEN cDNA 2010300F17 gene
chr10_-_120979327 0.06 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3
LEM domain containing 3
chr13_+_72632597 0.05 ENSMUST00000172353.1
Irx2
Iroquois related homeobox 2 (Drosophila)
chrX_+_42149534 0.05 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr11_+_83409137 0.05 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chr3_-_95411176 0.05 ENSMUST00000177599.1
Gm5070
predicted gene 5070
chr18_-_67449083 0.04 ENSMUST00000025408.8
Afg3l2
AFG3(ATPase family gene 3)-like 2 (yeast)
chr5_+_117413977 0.04 ENSMUST00000180430.1
Ksr2
kinase suppressor of ras 2
chr4_+_44981389 0.04 ENSMUST00000045078.6
ENSMUST00000128973.1
ENSMUST00000151148.1
Grhpr
glyoxylate reductase/hydroxypyruvate reductase
chr18_+_77185815 0.04 ENSMUST00000079618.4
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_+_44848991 0.03 ENSMUST00000107885.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr5_+_30105161 0.03 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr13_-_64497792 0.03 ENSMUST00000180282.1
1190003K10Rik
RIKEN cDNA 1190003K10 gene
chr11_-_69549108 0.03 ENSMUST00000108659.1
Dnah2
dynein, axonemal, heavy chain 2
chr5_-_62765618 0.02 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_29519790 0.02 ENSMUST00000168877.1
Gm17657
predicted gene, 17657
chr19_-_43752924 0.01 ENSMUST00000045562.5
Cox15
cytochrome c oxidase assembly protein 15
chr1_+_87264345 0.01 ENSMUST00000118687.1
ENSMUST00000027472.6
Efhd1
EF hand domain containing 1
chr16_+_30065333 0.00 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 2.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.4 3.5 GO:0036476 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.3 3.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 0.5 GO:0051885 positive regulation of anagen(GO:0051885)
0.2 3.0 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 0.7 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 2.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838) negative regulation of keratinocyte differentiation(GO:0045617)
0.2 1.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.5 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 1.6 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 1.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.3 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.7 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.8 GO:0032060 bleb assembly(GO:0032060)
0.0 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.3 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.9 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 3.4 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.6 GO:0006414 translational elongation(GO:0006414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.2 1.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.6 GO:0071439 clathrin complex(GO:0071439)
0.1 3.5 GO:0042588 zymogen granule(GO:0042588)
0.1 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.1 1.1 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.4 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 4.0 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 3.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.3 0.8 GO:0035500 MH2 domain binding(GO:0035500)
0.2 0.5 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 1.4 GO:0034711 inhibin binding(GO:0034711)
0.1 1.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 8.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 1.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 3.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 3.5 GO:0019838 growth factor binding(GO:0019838)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID AURORA A PATHWAY Aurora A signaling
0.0 4.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 4.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 2.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines