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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nkx6-1_Evx1_Hesx1

Z-value: 0.74

Motif logo

Transcription factors associated with Nkx6-1_Evx1_Hesx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000035187.8 NK6 homeobox 1
ENSMUSG00000005503.8 even-skipped homeobox 1
ENSMUSG00000040726.8 homeobox gene expressed in ES cells

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_1016652260.307.2e-02Click!
Hesx1mm10_v2_chr14_+_27000362_270005070.271.1e-01Click!

Activity profile of Nkx6-1_Evx1_Hesx1 motif

Sorted Z-values of Nkx6-1_Evx1_Hesx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_62765618 4.35 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_75564086 3.05 ENSMUST00000141062.1
ENSMUST00000152657.1
gamma-glutamyltransferase 1
chr3_-_75270073 2.95 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr18_+_4993795 2.60 ENSMUST00000153016.1
supervillin
chr15_-_101694299 2.05 ENSMUST00000023788.6
keratin 6A
chr14_+_27000362 2.01 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr12_+_38780284 1.89 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr3_-_116253467 1.79 ENSMUST00000090473.5
G-protein coupled receptor 88
chr2_+_69897255 1.76 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr2_+_84734050 1.73 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr15_+_25773985 1.68 ENSMUST00000125667.1
myosin X
chr10_-_28986280 1.60 ENSMUST00000152363.1
ENSMUST00000015663.6
RIKEN cDNA 2310057J18 gene
chr9_-_123678782 1.60 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr17_-_28560704 1.60 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chrX_+_56454871 1.54 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr5_-_53707532 1.45 ENSMUST00000031093.3
cholecystokinin A receptor
chr16_-_42340595 1.43 ENSMUST00000102817.4
growth associated protein 43
chr9_+_43310763 1.37 ENSMUST00000034511.5
tripartite motif-containing 29
chr15_-_79285502 1.35 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr12_+_38780817 1.28 ENSMUST00000160856.1
ets variant gene 1
chr4_+_8690399 1.24 ENSMUST00000127476.1
chromodomain helicase DNA binding protein 7
chr8_-_34965631 1.24 ENSMUST00000033929.4
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_-_123678873 1.24 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_-_168767029 1.14 ENSMUST00000075044.3
sal-like 4 (Drosophila)
chr13_+_44729535 1.10 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr9_+_113812547 1.10 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
CLIP associating protein 2
chrM_+_11734 1.07 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr18_+_23415400 1.06 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr6_+_29853746 1.02 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
S-adenosylhomocysteine hydrolase-like 2
chr10_+_127421208 1.01 ENSMUST00000168780.1
R3H domain containing 2
chr9_-_96719404 1.00 ENSMUST00000140121.1
zinc finger and BTB domain containing 38
chr8_-_107065632 0.99 ENSMUST00000034393.5
transmembrane emp24 protein transport domain containing 6
chr10_+_58394361 0.97 ENSMUST00000020077.4
LIM and senescent cell antigen-like domains 1
chr4_+_108719649 0.94 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr10_+_58394381 0.94 ENSMUST00000105468.1
LIM and senescent cell antigen-like domains 1
chr2_+_69219971 0.94 ENSMUST00000005364.5
ENSMUST00000112317.2
glucose-6-phosphatase, catalytic, 2
chr15_-_100424208 0.94 ENSMUST00000154331.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_+_144838590 0.94 ENSMUST00000105898.1
fibroblast growth factor 3
chr1_-_172027251 0.91 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr1_-_155417394 0.91 ENSMUST00000111775.1
ENSMUST00000111774.1
xenotropic and polytropic retrovirus receptor 1
chr13_+_94083490 0.89 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chrX_+_159303266 0.88 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr15_-_100424092 0.87 ENSMUST00000154676.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr6_+_121636173 0.86 ENSMUST00000032203.7
alpha-2-macroglobulin
chr4_+_103143052 0.85 ENSMUST00000106855.1
mesoderm induction early response 1 homolog (Xenopus laevis
chr19_+_23723279 0.85 ENSMUST00000067077.1
predicted gene 9938
chr10_+_94575257 0.85 ENSMUST00000121471.1
transmembrane and coiled coil domains 3
chr6_+_78370877 0.81 ENSMUST00000096904.3
regenerating islet-derived 3 beta
chrX_-_164250368 0.81 ENSMUST00000112263.1
BMX non-receptor tyrosine kinase
chr13_-_102906046 0.79 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr17_-_78684262 0.78 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr6_-_56923927 0.78 ENSMUST00000031793.5
5'-nucleotidase, cytosolic III
chr19_-_55241236 0.77 ENSMUST00000069183.6
guanylate cyclase 2g
chr6_+_41302265 0.77 ENSMUST00000031913.4
trypsin 4
chr16_+_33794008 0.77 ENSMUST00000115044.1
mucin 13, epithelial transmembrane
chr3_+_122044428 0.74 ENSMUST00000013995.8
ATP-binding cassette, sub-family A (ABC1), member 4
chr18_+_44104407 0.72 ENSMUST00000081271.5
serine peptidase inhibitor, Kazal type 11
chr3_-_145032765 0.71 ENSMUST00000029919.5
chloride channel calcium activated 3
chr17_-_48432723 0.71 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr13_+_23544052 0.71 ENSMUST00000075558.2
histone cluster 1, H3f
chr4_-_141846277 0.71 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr6_-_41035501 0.70 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr8_-_62123106 0.69 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr1_-_134955847 0.69 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr11_-_87359011 0.69 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr4_-_141846359 0.68 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr8_+_23411490 0.68 ENSMUST00000033952.7
secreted frizzled-related protein 1
chr9_+_96258697 0.68 ENSMUST00000179416.1
transcription factor Dp 2
chr1_-_174250976 0.68 ENSMUST00000061990.4
olfactory receptor 419
chr3_-_14778452 0.67 ENSMUST00000094365.4
carbonic anhydrase 1
chr1_-_132390301 0.67 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr6_-_41446062 0.67 ENSMUST00000095999.5
predicted gene 10334
chr15_-_100425050 0.65 ENSMUST00000123461.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_40515362 0.65 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr9_-_96719549 0.65 ENSMUST00000128269.1
zinc finger and BTB domain containing 38
chr15_-_79285470 0.64 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr1_+_139454747 0.64 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr17_+_3532554 0.64 ENSMUST00000168560.1
claudin 20
chr19_-_32196393 0.63 ENSMUST00000151822.1
sphingomyelin synthase 1
chr7_-_28547109 0.63 ENSMUST00000057974.3
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr4_-_42853888 0.62 ENSMUST00000107979.1
predicted gene 12429
chrX_+_49463926 0.62 ENSMUST00000130558.1
Rho GTPase activating protein 36
chrX_+_164090187 0.61 ENSMUST00000015545.3
transmembrane protein 27
chr2_-_79456750 0.61 ENSMUST00000041099.4
neurogenic differentiation 1
chr5_-_108795352 0.61 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr4_+_13743424 0.61 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_71019548 0.60 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr6_+_56924022 0.59 ENSMUST00000176838.1
vomeronasal 1 receptor 4
chr12_-_55014329 0.59 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr1_-_24612700 0.58 ENSMUST00000088336.1
predicted gene 10222
chr1_-_79440039 0.58 ENSMUST00000049972.4
secretogranin II
chrX_+_57212110 0.58 ENSMUST00000033466.1
CD40 ligand
chrX_-_74246534 0.58 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr3_-_130730375 0.58 ENSMUST00000079085.6
ribosomal protein L34
chr3_+_103832562 0.57 ENSMUST00000062945.5
BCLl2-like 15
chr9_-_15357692 0.56 ENSMUST00000098979.3
ENSMUST00000161132.1
RIKEN cDNA 5830418K08 gene
chr5_-_73191848 0.55 ENSMUST00000176910.1
furry homolog-like (Drosophila)
chr17_+_71019503 0.54 ENSMUST00000024847.7
myomesin 1
chr14_-_100149764 0.52 ENSMUST00000097079.4
Kruppel-like factor 12
chr18_-_68429235 0.52 ENSMUST00000052347.6
melanocortin 2 receptor
chr3_+_64081642 0.52 ENSMUST00000029406.4
vomeronasal 2, receptor 1
chr2_-_5676046 0.51 ENSMUST00000114987.3
calcium/calmodulin-dependent protein kinase ID
chrM_+_9870 0.51 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_34999111 0.51 ENSMUST00000114283.1
regulator of G-protein signaling 12
chr6_-_102464667 0.50 ENSMUST00000032159.6
contactin 3
chr18_-_24603464 0.50 ENSMUST00000154205.1
solute carrier family 39 (metal ion transporter), member 6
chr13_-_102905740 0.50 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr6_-_124779686 0.49 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
leucine rich repeat containing 23
chr2_+_57997884 0.49 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr8_+_4238815 0.49 ENSMUST00000003027.7
ENSMUST00000110999.1
mitogen-activated protein kinase kinase 7
chr4_+_119637704 0.49 ENSMUST00000024015.2
guanylate cyclase activator 2a (guanylin)
chr6_-_122340499 0.48 ENSMUST00000160843.1
polyhomeotic-like 1 (Drosophila)
chr11_+_67798269 0.48 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr10_-_117148474 0.48 ENSMUST00000020381.3
fibroblast growth factor receptor substrate 2
chr6_+_125552948 0.48 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr19_-_11640828 0.48 ENSMUST00000112984.2
membrane-spanning 4-domains, subfamily A, member 3
chr16_-_45724600 0.48 ENSMUST00000096057.4
transgelin 3
chr8_-_3625274 0.48 ENSMUST00000004749.6
Purkinje cell protein 2 (L7)
chr3_-_129755305 0.48 ENSMUST00000029653.2
epidermal growth factor
chr2_+_23069210 0.47 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chrX_-_9256899 0.47 ENSMUST00000115553.2
predicted gene 14862
chr3_+_103832741 0.47 ENSMUST00000106822.1
BCLl2-like 15
chr4_-_87806296 0.47 ENSMUST00000126353.1
ENSMUST00000149357.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_125068118 0.47 ENSMUST00000070353.3
solute carrier family 24, member 5
chr17_+_35841668 0.47 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr4_-_149126688 0.47 ENSMUST00000030815.2
cortistatin
chr1_+_88306731 0.47 ENSMUST00000040210.7
transient receptor potential cation channel, subfamily M, member 8
chrX_+_159697308 0.46 ENSMUST00000123433.1
SH3-domain kinase binding protein 1
chr9_+_54980880 0.46 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_+_110772604 0.44 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr5_-_66514815 0.44 ENSMUST00000161879.1
ENSMUST00000159357.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_-_56548013 0.44 ENSMUST00000182059.1
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr16_+_23146536 0.44 ENSMUST00000023593.5
ENSMUST00000171309.1
adiponectin, C1Q and collagen domain containing
chr8_-_105568298 0.44 ENSMUST00000005849.5
agouti related protein
chr8_-_24725762 0.44 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr19_-_34166037 0.44 ENSMUST00000025686.7
ankyrin repeat domain 22
chr15_+_44457522 0.43 ENSMUST00000166957.1
ENSMUST00000038336.5
polycystic kidney and hepatic disease 1-like 1
chr2_-_7395879 0.43 ENSMUST00000182404.1
CUGBP, Elav-like family member 2
chr6_+_8520008 0.43 ENSMUST00000162567.1
ENSMUST00000161217.1
glucocorticoid induced transcript 1
chr4_-_126201117 0.43 ENSMUST00000136157.1
thyroid hormone receptor associated protein 3
chr14_+_79515618 0.43 ENSMUST00000110835.1
E74-like factor 1
chr8_-_3624989 0.42 ENSMUST00000142431.1
Purkinje cell protein 2 (L7)
chr2_-_168767136 0.42 ENSMUST00000029061.5
ENSMUST00000103074.1
sal-like 4 (Drosophila)
chr11_-_118103492 0.42 ENSMUST00000132685.1
dynein, axonemal, heavy chain 17
chr2_-_116067391 0.41 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr4_+_19818722 0.41 ENSMUST00000035890.7
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr13_-_113663670 0.41 ENSMUST00000054650.4
heat shock protein 3
chr8_-_3625541 0.41 ENSMUST00000136105.1
Purkinje cell protein 2 (L7)
chr3_+_59952185 0.41 ENSMUST00000094227.3
predicted gene 9696
chr3_-_19264959 0.41 ENSMUST00000121951.1
phosphodiesterase 7A
chr3_-_100489324 0.41 ENSMUST00000061455.8
family with sequence similarity 46, member C
chr6_+_4755327 0.41 ENSMUST00000176551.1
paternally expressed 10
chr15_-_34356421 0.40 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr12_+_38781093 0.40 ENSMUST00000161513.1
ets variant gene 1
chr18_-_88927447 0.40 ENSMUST00000147313.1
suppressor of cytokine signaling 6
chr2_+_4559742 0.40 ENSMUST00000176828.1
FERM domain containing 4A
chr6_+_92092369 0.40 ENSMUST00000113463.1
nuclear receptor subfamily 2, group C, member 2
chr19_-_57197496 0.40 ENSMUST00000111544.1
actin-binding LIM protein 1
chr12_+_69963452 0.39 ENSMUST00000110560.1
predicted gene 3086
chr2_+_110721340 0.39 ENSMUST00000111016.2
mucin 15
chr5_+_103754560 0.39 ENSMUST00000153165.1
ENSMUST00000031256.5
AF4/FMR2 family, member 1
chr9_+_32116040 0.39 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr6_+_71909046 0.39 ENSMUST00000055296.8
polymerase (RNA) I polypeptide A
chr10_+_127420334 0.39 ENSMUST00000171434.1
R3H domain containing 2
chr12_+_109545390 0.38 ENSMUST00000146701.1
maternally expressed 3
chr12_-_4841583 0.38 ENSMUST00000020964.5
FK506 binding protein 1b
chr6_-_50456085 0.38 ENSMUST00000146341.1
ENSMUST00000071728.4
oxysterol binding protein-like 3
chr11_-_62392605 0.38 ENSMUST00000151498.2
ENSMUST00000159069.1
nuclear receptor co-repressor 1
chr2_+_110721587 0.37 ENSMUST00000111017.2
mucin 15
chr12_+_81631369 0.37 ENSMUST00000036116.5
tetratricopeptide repeat domain 9
chr5_+_34999070 0.37 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr4_-_99654983 0.37 ENSMUST00000136525.1
predicted gene 12688
chr2_-_58160495 0.37 ENSMUST00000028175.6
cytohesin 1 interacting protein
chr11_+_23666479 0.36 ENSMUST00000143117.1
pseudouridylate synthase 10
chr6_-_136781718 0.36 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chr17_-_40794063 0.36 ENSMUST00000131699.1
ENSMUST00000024724.7
ENSMUST00000144243.1
cysteine-rich secretory protein 2
chr12_+_117516479 0.36 ENSMUST00000109691.2
Rap guanine nucleotide exchange factor (GEF) 5
chr13_+_23574381 0.36 ENSMUST00000090776.4
histone cluster 1, H2ad
chr12_-_54986363 0.35 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr2_+_86007778 0.35 ENSMUST00000062166.1
olfactory receptor 1032
chr3_+_66219909 0.35 ENSMUST00000029421.5
pentraxin related gene
chr9_+_38877126 0.35 ENSMUST00000078289.2
olfactory receptor 926
chr9_-_112187766 0.35 ENSMUST00000111872.2
ENSMUST00000164754.2
cyclic AMP-regulated phosphoprotein, 21
chr5_+_34999046 0.34 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr11_-_77188968 0.34 ENSMUST00000108400.1
EF-hand calcium binding domain 5
chrX_-_139871637 0.34 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr11_+_23306910 0.34 ENSMUST00000137823.1
ubiquitin specific peptidase 34
chr12_+_31438209 0.34 ENSMUST00000001254.5
solute carrier family 26, member 3
chr15_-_8710734 0.34 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_37703845 0.34 ENSMUST00000155237.1
spermatid perinuclear RNA binding protein
chr17_+_35916977 0.33 ENSMUST00000151664.1
protein phosphatase 1, regulatory subunit 10
chr19_+_34100943 0.33 ENSMUST00000025685.6
lipase, family member M
chr2_-_132111440 0.33 ENSMUST00000128899.1
solute carrier family 23 (nucleobase transporters), member 2
chr8_-_3625025 0.33 ENSMUST00000133459.1
Purkinje cell protein 2 (L7)
chr5_+_121777929 0.33 ENSMUST00000160821.1
ataxin 2
chr10_-_62814539 0.33 ENSMUST00000173087.1
ENSMUST00000174121.1
tet methylcytosine dioxygenase 1
chr13_-_62607499 0.33 ENSMUST00000091563.4
RIKEN cDNA 6720489N17 gene
chr2_-_45112890 0.33 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chr7_+_126776939 0.32 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr9_+_13621646 0.32 ENSMUST00000034401.8
mastermind like 2 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0035524 proline transmembrane transport(GO:0035524)
0.5 2.5 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.5 1.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.5 1.9 GO:0061743 motor learning(GO:0061743)
0.4 1.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 1.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.4 3.0 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4 1.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 0.7 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 1.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 3.0 GO:0030916 otic vesicle formation(GO:0030916)
0.3 0.9 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 1.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 1.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 3.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.6 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.6 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.2 0.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 1.6 GO:0016198 axon choice point recognition(GO:0016198)
0.2 0.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.9 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0001878 response to yeast(GO:0001878)
0.1 0.3 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.2 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 1.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.8 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 2.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.2 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.1 0.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.1 GO:0044146 negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:0061738 mitotic cytokinesis checkpoint(GO:0044878) late endosomal microautophagy(GO:0061738) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 1.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:1900239 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.3 GO:0035566 regulation of metanephros size(GO:0035566)
0.1 0.7 GO:0050955 thermoception(GO:0050955)
0.1 0.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661) negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.7 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.4 GO:0051775 response to redox state(GO:0051775)
0.1 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.0 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.2 GO:0045575 basophil activation(GO:0045575)
0.0 0.2 GO:0015888 thiamine transport(GO:0015888)
0.0 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.2 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 1.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.4 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.8 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0090260 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.4 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:0035926 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:1904339 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 1.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.0 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.3 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 1.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 1.3 GO:0007586 digestion(GO:0007586)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 2.1 GO:0007519 skeletal muscle tissue development(GO:0007519)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.2 0.9 GO:0008623 CHRAC(GO:0008623)
0.2 2.0 GO:0071439 clathrin complex(GO:0071439)
0.2 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.5 GO:0031527 filopodium membrane(GO:0031527)
0.1 3.4 GO:0043034 costamere(GO:0043034)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.4 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 1.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.7 GO:0031672 A band(GO:0031672)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0070695 HOPS complex(GO:0030897) FHF complex(GO:0070695)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 1.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.9 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 0.9 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 0.9 GO:0043120 interleukin-8 binding(GO:0019959) tumor necrosis factor binding(GO:0043120)
0.3 2.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 3.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 1.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 4.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.7 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0042166 acetylcholine binding(GO:0042166)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 3.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.8 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 3.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 2.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.5 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.8 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 6.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.1 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling