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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nr3c2

Z-value: 0.31

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
Nr3c2
ENSMUSG00000031618.7 nuclear receptor subfamily 3, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_76902476-0.231.8e-01Click!

Activity profile of Nr3c2 motif

Sorted Z-values of Nr3c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_125320633 0.67 ENSMUST00000176655.1
ENSMUST00000176110.1
Scnn1a
sodium channel, nonvoltage-gated 1 alpha
chr14_-_68533689 0.43 ENSMUST00000022640.7
Adam7
a disintegrin and metallopeptidase domain 7
chr4_-_49408042 0.39 ENSMUST00000081541.2
Acnat2
acyl-coenzyme A amino acid N-acyltransferase 2
chr3_-_95904683 0.37 ENSMUST00000147962.1
ENSMUST00000036181.8
Car14
carbonic anhydrase 14
chr11_+_101448403 0.36 ENSMUST00000010502.6
Ifi35
interferon-induced protein 35
chr9_+_123366921 0.30 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr7_-_25390098 0.29 ENSMUST00000054301.7
Lipe
lipase, hormone sensitive
chr11_+_98386450 0.27 ENSMUST00000041301.7
Pnmt
phenylethanolamine-N-methyltransferase
chr15_-_97020322 0.25 ENSMUST00000166223.1
Slc38a4
solute carrier family 38, member 4
chr5_+_112288734 0.25 ENSMUST00000151947.1
Tpst2
protein-tyrosine sulfotransferase 2
chr14_+_53763083 0.21 ENSMUST00000180859.1
ENSMUST00000103589.4
Trav14-3
T cell receptor alpha variable 14-3
chr5_-_24601961 0.20 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_171240055 0.20 ENSMUST00000131286.1
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr8_+_70697739 0.20 ENSMUST00000095267.4
Jund
Jun proto-oncogene related gene d
chr15_+_102102926 0.18 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1
tensin like C1 domain-containing phosphatase
chr11_-_75454656 0.17 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr13_-_119912752 0.16 ENSMUST00000179502.1
Gm21761
predicted gene, 21761
chr3_-_88739692 0.16 ENSMUST00000090946.2
Gm10253
predicted gene 10253
chr2_-_91444622 0.14 ENSMUST00000064652.7
ENSMUST00000102594.4
ENSMUST00000094835.2
1110051M20Rik
RIKEN cDNA 1110051M20 gene
chr14_+_70530819 0.14 ENSMUST00000047331.6
Lgi3
leucine-rich repeat LGI family, member 3
chr13_+_22293193 0.13 ENSMUST00000091735.1
Vmn1r196
vomeronasal 1 receptor 196
chr6_-_69400097 0.13 ENSMUST00000177795.1
Igkv4-62
immunoglobulin kappa variable 4-62
chr4_+_104913456 0.12 ENSMUST00000106803.2
ENSMUST00000106804.1
1700024P16Rik
RIKEN cDNA 1700024P16 gene
chr13_+_120173184 0.11 ENSMUST00000178828.1
Gm21818
predicted gene, 21818
chr5_-_31697598 0.11 ENSMUST00000031018.7
Rbks
ribokinase
chr13_+_120317567 0.10 ENSMUST00000178349.1
Tcstv3
2-cell-stage, variable group, member 3
chr1_-_157256682 0.09 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr6_+_34863130 0.08 ENSMUST00000074949.3
Tmem140
transmembrane protein 140
chr5_+_146481943 0.06 ENSMUST00000179032.1
Gm6408
predicted gene 6408
chr5_+_31697665 0.06 ENSMUST00000080598.7
Bre
brain and reproductive organ-expressed protein
chr10_-_14718191 0.06 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr17_-_23312313 0.05 ENSMUST00000168033.1
Vmn2r114
vomeronasal 2, receptor 114
chr13_+_120154627 0.05 ENSMUST00000179071.1
Gm20767
predicted gene, 20767
chr9_+_99612468 0.04 ENSMUST00000042553.7
A4gnt
alpha-1,4-N-acetylglucosaminyltransferase
chr13_+_99100698 0.04 ENSMUST00000181742.1
Gm807
predicted gene 807
chr9_-_75597643 0.04 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr5_+_123142187 0.04 ENSMUST00000174836.1
ENSMUST00000163030.2
Setd1b
SET domain containing 1B
chr16_-_96192222 0.04 ENSMUST00000113804.1
ENSMUST00000054855.7
Lca5l
Leber congenital amaurosis 5-like
chrX_-_102854616 0.03 ENSMUST00000120314.1
Dmrtc1c2
DMRT-like family C1c2
chr10_+_21993890 0.03 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr15_-_82047579 0.03 ENSMUST00000166578.1
ENSMUST00000080622.7
Nhp2l1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr14_-_8309770 0.03 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a
family with sequence similarity 107, member A
chr1_-_74935549 0.02 ENSMUST00000094844.3
Ccdc108
coiled-coil domain containing 108
chrX_+_102802963 0.02 ENSMUST00000118218.1
Dmrtc1c1
DMRT-like family C1c1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr3c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.3 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.7 GO:0050891 multicellular organismal water homeostasis(GO:0050891)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.7 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis