Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Pax2

Z-value: 1.70

Motif logo

Transcription factors associated with Pax2

Gene Symbol Gene ID Gene Info
ENSMUSG00000004231.9 paired box 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax2mm10_v2_chr19_+_44757394_44757394-0.271.1e-01Click!

Activity profile of Pax2 motif

Sorted Z-values of Pax2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_84450944 5.68 ENSMUST00000085192.5
aldehyde dehydrogenase family 6, subfamily A1
chr14_+_55560010 3.98 ENSMUST00000147981.1
ENSMUST00000133256.1
DDB1 and CUL4 associated factor 11
chr1_+_106171752 3.92 ENSMUST00000061047.6
PH domain and leucine rich repeat protein phosphatase 1
chr6_+_17463927 3.71 ENSMUST00000115442.1
met proto-oncogene
chr14_+_55560904 3.67 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr5_-_66151323 3.42 ENSMUST00000131838.1
RNA binding motif protein 47
chr13_-_92131494 3.31 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr14_+_55560480 2.99 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr5_-_151190154 2.71 ENSMUST00000062015.8
ENSMUST00000110483.2
StAR-related lipid transfer (START) domain containing 13
chr14_-_18239053 2.67 ENSMUST00000090543.5
nuclear receptor subfamily 1, group D, member 2
chr5_-_66151903 2.51 ENSMUST00000167950.1
RNA binding motif protein 47
chr14_-_47189406 2.47 ENSMUST00000089959.6
GTP cyclohydrolase 1
chr17_+_24850515 2.44 ENSMUST00000154363.1
ENSMUST00000169200.1
hydroxyacyl glutathione hydrolase
chr16_+_45158725 2.43 ENSMUST00000023343.3
autophagy related 3
chr9_+_44067072 2.37 ENSMUST00000177054.1
ubiquitin specific peptidase 2
chr3_+_90052814 2.36 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
RIKEN cDNA 4933434E20 gene
chr16_-_45158624 2.25 ENSMUST00000180636.1
solute carrier family 35, member A5
chr4_-_155345696 2.24 ENSMUST00000103178.4
protein kinase C, zeta
chr13_-_64274962 2.24 ENSMUST00000039318.8
CDC14 cell division cycle 14B
chr6_+_121343385 2.24 ENSMUST00000168295.1
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr16_-_45158650 2.21 ENSMUST00000023344.3
solute carrier family 35, member A5
chr9_+_46012822 2.20 ENSMUST00000120463.2
ENSMUST00000120247.1
SIK family kinase 3
chr17_+_24850484 2.13 ENSMUST00000118788.1
hydroxyacyl glutathione hydrolase
chr15_-_81399594 2.09 ENSMUST00000023039.8
suppression of tumorigenicity 13
chr19_+_37685581 2.08 ENSMUST00000073391.4
cytochrome P450, family 26, subfamily c, polypeptide 1
chr9_+_44066993 2.05 ENSMUST00000034508.7
ubiquitin specific peptidase 2
chr3_+_95318782 2.03 ENSMUST00000139866.1
ceramide synthase 2
chr9_+_46012810 2.00 ENSMUST00000126865.1
SIK family kinase 3
chr1_+_88211956 1.99 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr17_+_26715644 1.97 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
CREB3 regulatory factor
chr2_+_155382186 1.96 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr15_+_99393610 1.95 ENSMUST00000159531.1
transmembrane BAX inhibitor motif containing 6
chr10_+_41519493 1.94 ENSMUST00000019962.8
CD164 antigen
chr15_+_99393574 1.90 ENSMUST00000162624.1
transmembrane BAX inhibitor motif containing 6
chr8_+_13159135 1.90 ENSMUST00000033824.6
lysosomal-associated membrane protein 1
chr14_-_55560340 1.89 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chr3_-_95882031 1.86 ENSMUST00000161994.1
predicted gene 129
chr13_-_64274879 1.86 ENSMUST00000109770.1
CDC14 cell division cycle 14B
chr11_+_35769462 1.85 ENSMUST00000018990.7
pantothenate kinase 3
chr16_-_45158566 1.84 ENSMUST00000181177.1
solute carrier family 35, member A5
chr16_-_45158183 1.83 ENSMUST00000114600.1
solute carrier family 35, member A5
chr10_+_127063527 1.80 ENSMUST00000006911.5
cyclin-dependent kinase 4
chr14_+_55559993 1.77 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr1_-_136960427 1.75 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr3_-_146596588 1.74 ENSMUST00000029836.4
deoxyribonuclease II beta
chr15_+_99393219 1.73 ENSMUST00000159209.1
transmembrane BAX inhibitor motif containing 6
chr1_+_128244122 1.72 ENSMUST00000027592.3
UBX domain protein 4
chr10_-_62486575 1.69 ENSMUST00000092473.3
vacuolar protein sorting 26 homolog A (yeast)
chr11_-_101171302 1.68 ENSMUST00000164474.1
ENSMUST00000043397.7
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr4_+_62360695 1.65 ENSMUST00000084526.5
solute carrier family 31, member 1
chr7_-_130266237 1.64 ENSMUST00000117872.1
ENSMUST00000120187.1
fibroblast growth factor receptor 2
chr5_+_24428208 1.62 ENSMUST00000115049.2
solute carrier family 4 (anion exchanger), member 2
chr1_-_191397026 1.62 ENSMUST00000067976.3
protein phosphatase 2, regulatory subunit B (B56), alpha isoform
chr7_-_127946725 1.58 ENSMUST00000118755.1
ENSMUST00000094026.3
protease, serine, 36
chr8_-_84846860 1.58 ENSMUST00000003912.6
calreticulin
chr5_+_138171997 1.56 ENSMUST00000019662.4
ENSMUST00000151318.1
adaptor-related protein complex AP-4, mu 1
chr17_+_46383725 1.53 ENSMUST00000113481.1
ENSMUST00000138127.1
zinc finger protein 318
chr10_-_62486772 1.53 ENSMUST00000105447.3
vacuolar protein sorting 26 homolog A (yeast)
chr2_+_155381808 1.52 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr16_-_45158453 1.49 ENSMUST00000181750.1
solute carrier family 35, member A5
chr6_-_113531575 1.47 ENSMUST00000032425.5
ER membrane protein complex subunit 3
chr15_-_81400043 1.46 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
suppression of tumorigenicity 13
chr17_-_26939464 1.43 ENSMUST00000025027.8
ENSMUST00000114935.1
cutA divalent cation tolerance homolog (E. coli)
chr11_-_101170327 1.41 ENSMUST00000123864.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_-_130266191 1.41 ENSMUST00000122054.1
fibroblast growth factor receptor 2
chr16_-_44139003 1.40 ENSMUST00000124102.1
ATPase, H+ transporting, lysosomal V1 subunit A
chr15_+_81400132 1.38 ENSMUST00000163754.1
ENSMUST00000041609.4
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr11_-_50325599 1.37 ENSMUST00000179865.1
ENSMUST00000020637.8
calnexin
chr16_-_44139196 1.32 ENSMUST00000063661.6
ENSMUST00000114666.2
ATPase, H+ transporting, lysosomal V1 subunit A
chr3_+_96635617 1.32 ENSMUST00000048766.8
peroxisomal biogenesis factor 11 beta
chr2_+_166805506 1.32 ENSMUST00000099078.3
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr4_+_155847393 1.31 ENSMUST00000030948.9
ENSMUST00000168552.1
dishevelled, dsh homolog 1 (Drosophila)
chr1_-_183297008 1.31 ENSMUST00000057062.5
BRO1 domain and CAAX motif containing
chr14_-_72602945 1.31 ENSMUST00000162825.1
fibronectin type III domain containing 3A
chr2_+_18672384 1.30 ENSMUST00000171845.1
ENSMUST00000061158.4
COMM domain containing 3
chr6_-_33060172 1.29 ENSMUST00000115091.1
ENSMUST00000127666.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_126707319 1.28 ENSMUST00000028841.7
ENSMUST00000110416.2
ubiquitin specific peptidase 8
chr19_+_21653302 1.28 ENSMUST00000052556.3
abhydrolase domain containing 17B
chr4_-_148038769 1.27 ENSMUST00000030879.5
ENSMUST00000137724.1
chloride channel 6
chr19_-_42128982 1.27 ENSMUST00000161873.1
arginine vasopressin-induced 1
chr6_-_33060256 1.24 ENSMUST00000066379.4
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_164833781 1.24 ENSMUST00000143780.1
cathepsin A
chr7_-_63212514 1.23 ENSMUST00000032738.5
cholinergic receptor, nicotinic, alpha polypeptide 7
chr15_+_59648644 1.23 ENSMUST00000118228.1
tribbles homolog 1 (Drosophila)
chr3_+_96635430 1.23 ENSMUST00000118557.1
peroxisomal biogenesis factor 11 beta
chr4_+_99295900 1.22 ENSMUST00000094955.1
predicted gene 12689
chr4_+_138454305 1.22 ENSMUST00000050918.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_+_110018301 1.22 ENSMUST00000084731.3
importin 7
chr2_+_91457501 1.22 ENSMUST00000028689.3
low density lipoprotein receptor-related protein 4
chr13_+_13590402 1.19 ENSMUST00000110559.1
lysosomal trafficking regulator
chr16_-_44139630 1.18 ENSMUST00000137557.1
ENSMUST00000147025.1
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_+_48949495 1.16 ENSMUST00000112745.1
methyl-CpG binding domain protein 5
chr17_-_24850290 1.15 ENSMUST00000049642.4
fumarylacetoacetate hydrolase domain containing 1
chr17_+_80944611 1.13 ENSMUST00000025092.4
transmembrane protein 178
chr3_-_89913144 1.13 ENSMUST00000029559.6
interleukin 6 receptor, alpha
chr3_+_96635817 1.12 ENSMUST00000139739.1
peroxisomal biogenesis factor 11 beta
chr11_-_119040905 1.11 ENSMUST00000026663.7
chromobox 8
chr11_-_120630516 1.11 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr2_-_37703845 1.10 ENSMUST00000155237.1
spermatid perinuclear RNA binding protein
chr9_-_91365756 1.10 ENSMUST00000034927.6
zinc finger protein of the cerebellum 1
chr17_-_90088343 1.10 ENSMUST00000173917.1
neurexin I
chr3_+_96635840 1.09 ENSMUST00000165842.1
peroxisomal biogenesis factor 11 beta
chr1_+_87327044 1.08 ENSMUST00000173173.1
GRB10 interacting GYF protein 2
chr19_-_60468304 1.08 ENSMUST00000051277.2
prolactin releasing hormone receptor
chr4_-_129189600 1.07 ENSMUST00000117497.1
ENSMUST00000117350.1
S100P binding protein
chr15_+_59648350 1.07 ENSMUST00000067543.6
tribbles homolog 1 (Drosophila)
chr5_-_65697856 1.07 ENSMUST00000031104.6
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr19_-_42129043 1.06 ENSMUST00000018965.3
arginine vasopressin-induced 1
chr10_-_63339023 1.06 ENSMUST00000177694.1
ENSMUST00000020257.6
ENSMUST00000105442.2
sirtuin 1
chr19_-_60581013 1.05 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
CDK2 associated, cullin domain 1
chr7_+_125707893 1.05 ENSMUST00000069660.6
ENSMUST00000142464.1
RIKEN cDNA D430042O09 gene
chr18_+_36281069 1.03 ENSMUST00000051301.3
purine rich element binding protein A
chr15_-_53346118 1.01 ENSMUST00000077273.2
exostoses (multiple) 1
chr4_-_89311021 1.01 ENSMUST00000097981.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_171345684 1.01 ENSMUST00000006579.4
prefoldin 2
chr4_-_126202335 1.01 ENSMUST00000142125.1
ENSMUST00000106141.2
thyroid hormone receptor associated protein 3
chr16_-_5049882 0.99 ENSMUST00000023189.7
ENSMUST00000115844.1
glyoxylate reductase 1 homolog (Arabidopsis)
chr1_+_87327008 0.99 ENSMUST00000172794.1
ENSMUST00000164992.2
GRB10 interacting GYF protein 2
chr18_-_31609893 0.98 ENSMUST00000060396.6
solute carrier family 25, member 46
chr11_+_120673359 0.97 ENSMUST00000135346.1
ENSMUST00000127269.1
ENSMUST00000131727.2
ENSMUST00000149389.1
ENSMUST00000153346.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr17_+_44188564 0.96 ENSMUST00000024755.5
chloride intracellular channel 5
chr2_+_164833841 0.96 ENSMUST00000152721.1
cathepsin A
chr1_-_10232670 0.94 ENSMUST00000088615.4
ENSMUST00000131556.1
ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
chr7_+_44850393 0.94 ENSMUST00000136232.1
AKT1 substrate 1 (proline-rich)
chr7_+_46796088 0.93 ENSMUST00000006774.4
ENSMUST00000165031.1
general transcription factor II H, polypeptide 1
chr3_-_95882193 0.89 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
predicted gene 129
chr7_+_125707945 0.89 ENSMUST00000148701.1
RIKEN cDNA D430042O09 gene
chr11_+_53350783 0.88 ENSMUST00000060945.5
AF4/FMR2 family, member 4
chr12_+_84451485 0.86 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr17_-_56074932 0.85 ENSMUST00000019722.5
UBX domain protein 6
chr1_-_82291370 0.85 ENSMUST00000069799.2
insulin receptor substrate 1
chr16_-_5203981 0.85 ENSMUST00000147567.1
ENSMUST00000023911.4
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_97962581 0.84 ENSMUST00000113734.2
ENSMUST00000052089.7
ENSMUST00000063605.7
zinc finger and BTB domain containing 21
chr9_+_58582397 0.84 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
neuroplastin
chr2_-_28916412 0.81 ENSMUST00000050776.2
ENSMUST00000113849.1
BarH-like 1 (Drosophila)
chr6_+_143167210 0.81 ENSMUST00000032413.4
ethanolamine kinase 1
chr1_-_183297256 0.81 ENSMUST00000163528.2
BRO1 domain and CAAX motif containing
chr17_-_27820445 0.80 ENSMUST00000114859.1
DNA segment, Chr 17, Wayne State University 92, expressed
chr4_-_129189512 0.80 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
S100P binding protein
chr19_-_7105729 0.80 ENSMUST00000113383.2
fibronectin leucine rich transmembrane protein 1
chr11_+_120673018 0.80 ENSMUST00000106158.2
ENSMUST00000103016.1
ENSMUST00000168714.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr14_+_31019159 0.80 ENSMUST00000112094.1
ENSMUST00000144009.1
polybromo 1
chr7_-_45459839 0.79 ENSMUST00000094434.4
ferritin light chain 1
chr15_+_102921103 0.79 ENSMUST00000001700.6
homeobox C13
chr5_+_117363513 0.79 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr12_-_55492587 0.78 ENSMUST00000021413.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr11_-_120630126 0.77 ENSMUST00000106180.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr17_-_27820534 0.77 ENSMUST00000075076.4
ENSMUST00000114863.2
DNA segment, Chr 17, Wayne State University 92, expressed
chr14_+_21500879 0.76 ENSMUST00000182964.1
K(lysine) acetyltransferase 6B
chr7_+_28179469 0.75 ENSMUST00000085901.6
ENSMUST00000172761.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr4_+_127077374 0.74 ENSMUST00000046751.6
ENSMUST00000094713.3
zinc finger, MYM-type 6
chr5_-_124425572 0.73 ENSMUST00000168651.1
sno, strawberry notch homolog 1 (Drosophila)
chr1_-_130715734 0.72 ENSMUST00000066863.6
ENSMUST00000050406.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr10_-_29362032 0.72 ENSMUST00000160372.1
ring finger protein 146
chrX_+_36328353 0.72 ENSMUST00000016383.3
LON peptidase N-terminal domain and ring finger 3
chr9_+_122572493 0.71 ENSMUST00000181682.1
ENSMUST00000181107.1
ENSMUST00000181719.1
RIKEN cDNA 9530059O14 gene
chr13_-_64153194 0.71 ENSMUST00000059817.4
ENSMUST00000117241.1
zinc finger protein 367
chr14_+_31019125 0.70 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
polybromo 1
chr7_+_134670667 0.69 ENSMUST00000084488.4
dedicator of cytokinesis 1
chr17_-_63863791 0.69 ENSMUST00000050753.3
RIKEN cDNA A930002H24 gene
chr6_+_137735078 0.69 ENSMUST00000064910.6
serine/threonine kinase receptor associated protein
chr2_+_180929000 0.68 ENSMUST00000108875.1
baculoviral IAP repeat-containing 7 (livin)
chr11_-_76846968 0.67 ENSMUST00000021201.5
carboxypeptidase D
chr14_+_34673948 0.65 ENSMUST00000090027.3
wings apart-like homolog (Drosophila)
chr7_+_127841752 0.64 ENSMUST00000033075.7
syntaxin 4A (placental)
chr4_-_129189646 0.64 ENSMUST00000106059.1
S100P binding protein
chr4_-_119422355 0.64 ENSMUST00000106316.1
ENSMUST00000030385.6
phosphopantothenoylcysteine synthetase
chr14_+_34674122 0.63 ENSMUST00000169910.1
wings apart-like homolog (Drosophila)
chr17_+_33824591 0.62 ENSMUST00000048249.6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chr1_+_120602405 0.62 ENSMUST00000079721.7
engrailed 1
chr3_-_123236134 0.62 ENSMUST00000106427.1
ENSMUST00000106426.1
ENSMUST00000051443.5
synaptopodin 2
chr5_+_90786100 0.61 ENSMUST00000031326.8
chemokine (C-X-C motif) ligand 3
chr2_-_30286312 0.60 ENSMUST00000100219.3
dolichol kinase
chr17_+_45563928 0.60 ENSMUST00000041353.6
solute carrier family 35, member B2
chr2_-_28916668 0.60 ENSMUST00000113847.1
BarH-like 1 (Drosophila)
chr14_-_31019055 0.60 ENSMUST00000037739.6
guanine nucleotide binding protein-like 3 (nucleolar)
chr6_-_149188648 0.60 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
antagonist of mitotic exit network 1
chr4_-_58911902 0.58 ENSMUST00000134848.1
ENSMUST00000107557.2
ENSMUST00000149301.1
expressed sequence AI314180
chr3_+_58692589 0.58 ENSMUST00000181771.1
RIKEN cDNA 4930593A02 gene
chr9_-_91365778 0.56 ENSMUST00000065360.3
zinc finger protein of the cerebellum 1
chr2_+_19658055 0.56 ENSMUST00000052168.4
OTU domain containing 1
chr6_-_108185552 0.55 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
sulfatase modifying factor 1
chr2_+_71786923 0.53 ENSMUST00000112101.1
ENSMUST00000028522.3
integrin alpha 6
chr3_-_133544390 0.53 ENSMUST00000098603.3
tet methylcytosine dioxygenase 2
chr16_+_58727910 0.53 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
claudin 25
chr1_+_60977898 0.52 ENSMUST00000027162.5
ENSMUST00000102827.3
inducible T cell co-stimulator
chr17_-_56609689 0.51 ENSMUST00000052832.5
RIKEN cDNA 2410015M20 gene
chr6_-_6217023 0.51 ENSMUST00000015256.8
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr9_+_56937462 0.51 ENSMUST00000034827.8
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr10_-_29362012 0.50 ENSMUST00000161508.1
ring finger protein 146
chr17_-_65613521 0.49 ENSMUST00000024897.8
vesicle-associated membrane protein, associated protein A
chr3_-_95882232 0.49 ENSMUST00000161866.1
predicted gene 129
chr18_-_80713062 0.48 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr5_+_65199691 0.47 ENSMUST00000041892.8
WD repeat domain 19
chr7_-_46795881 0.47 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hermansky-Pudlak syndrome 5 homolog (human)
chr13_-_107890059 0.46 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chr11_-_102230127 0.46 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
histone deacetylase 5
chrX_+_7884321 0.46 ENSMUST00000096514.3
ENSMUST00000123277.1
solute carrier family 35 (UDP-galactose transporter), member A2
chr4_-_108833608 0.44 ENSMUST00000102742.4
basic transcription factor 3-like 4
chr9_+_35267857 0.43 ENSMUST00000034543.4
RNA pseudouridylate synthase domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.1 5.6 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.0 3.0 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365)
0.8 4.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.8 3.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.8 2.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.7 2.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.7 2.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.6 1.9 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.6 2.5 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.6 5.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 2.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.5 2.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.5 3.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 2.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.5 2.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012) negative regulation of glial cell migration(GO:1903976)
0.5 1.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.5 4.6 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.4 3.6 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.4 1.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 1.2 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.4 4.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 1.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 1.7 GO:0072719 cellular response to cisplatin(GO:0072719)
0.3 2.0 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 2.2 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.3 1.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.3 1.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.3 1.1 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 1.8 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 1.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.9 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 1.6 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2 0.6 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.6 GO:0061743 motor learning(GO:0061743)
0.2 1.6 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.2 4.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 0.8 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 3.0 GO:0042407 cristae formation(GO:0042407)
0.2 0.4 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.9 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 3.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 0.5 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 0.5 GO:0061055 myotome development(GO:0061055)
0.1 2.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 2.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 1.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 1.3 GO:0071340 protein localization to microtubule(GO:0035372) skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 3.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 3.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 2.4 GO:0050765 nucleophagy(GO:0044804) negative regulation of phagocytosis(GO:0050765)
0.1 1.3 GO:0035878 nail development(GO:0035878)
0.1 0.8 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.9 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.3 GO:0003285 septum secundum development(GO:0003285) cardiac muscle tissue regeneration(GO:0061026) negative regulation of connective tissue replacement(GO:1905204)
0.1 1.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 4.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 2.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.9 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.0 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.6 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 1.0 GO:0090148 membrane fission(GO:0090148)
0.1 1.4 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.8 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 0.7 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.0 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 12.3 GO:0008643 carbohydrate transport(GO:0008643)
0.1 0.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 2.3 GO:0007032 endosome organization(GO:0007032)
0.1 0.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 2.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 1.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 1.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.7 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.4 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 2.9 GO:0006821 chloride transport(GO:0006821)
0.0 1.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 2.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 1.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 1.6 GO:0016236 macroautophagy(GO:0016236)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.4 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.6 1.9 GO:0032010 phagolysosome(GO:0032010)
0.4 3.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 3.0 GO:0061617 MICOS complex(GO:0061617)
0.3 1.3 GO:0032280 symmetric synapse(GO:0032280)
0.3 12.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 1.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 2.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.2 1.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 0.7 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 4.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 2.2 GO:0043203 axon hillock(GO:0043203) apical cortex(GO:0045179)
0.1 2.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.2 GO:0016600 flotillin complex(GO:0016600)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.9 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.9 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.3 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 5.8 GO:0005776 autophagosome(GO:0005776)
0.1 1.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 1.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 4.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 10.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 5.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 6.2 GO:0005938 cell cortex(GO:0005938)
0.0 4.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 6.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.9 3.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.8 2.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.7 2.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.5 4.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.4 10.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.4 1.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 2.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.4 3.6 GO:0032564 dATP binding(GO:0032564)
0.4 1.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.4 2.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 1.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 1.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.3 3.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 1.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 1.1 GO:0016822 oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 2.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 3.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 2.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 3.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 0.5 GO:0030519 snoRNP binding(GO:0030519)
0.2 0.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 3.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 5.5 GO:0030332 cyclin binding(GO:0030332)
0.1 1.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.8 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 5.7 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.2 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.7 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 4.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 5.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 4.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 3.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.8 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0005254 chloride channel activity(GO:0005254)
0.0 6.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.0 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 5.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 3.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 2.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 2.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 3.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 3.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 4.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.1 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription