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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Rarb

Z-value: 1.20

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Transcription factors associated with Rarb

Gene Symbol Gene ID Gene Info
Rarb
ENSMUSG00000017491.8 retinoic acid receptor, beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rarbmm10_v2_chr14_-_16575456_16575501-0.048.1e-01Click!

Activity profile of Rarb motif

Sorted Z-values of Rarb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_85820965 15.85 ENSMUST00000032074.3
Cml5
camello-like 5
chr5_-_87254804 8.07 ENSMUST00000075858.3
Ugt2b37
UDP glucuronosyltransferase 2 family, polypeptide B37
chr6_-_85820936 6.16 ENSMUST00000174143.1
Gm11128
predicted gene 11128
chr6_-_138073196 5.20 ENSMUST00000050132.3
Slc15a5
solute carrier family 15, member 5
chr9_-_46235631 4.56 ENSMUST00000118649.1
Apoc3
apolipoprotein C-III
chr5_-_87092546 4.32 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr17_+_12584183 3.89 ENSMUST00000046959.7
Slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr8_+_36489191 3.43 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr5_-_87140318 2.92 ENSMUST00000067790.6
ENSMUST00000113327.1
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr11_+_76904475 2.32 ENSMUST00000142166.1
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr5_+_87000838 2.24 ENSMUST00000031186.7
Ugt2b35
UDP glucuronosyltransferase 2 family, polypeptide B35
chr19_+_28990476 2.13 ENSMUST00000050148.3
Cdc37l1
cell division cycle 37-like 1
chr1_+_4807823 1.79 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
Lypla1
lysophospholipase 1
chr5_-_86906937 1.64 ENSMUST00000031181.9
ENSMUST00000113333.1
Ugt2b34
UDP glucuronosyltransferase 2 family, polypeptide B34
chr10_-_126901315 1.38 ENSMUST00000026504.5
ENSMUST00000168520.1
Xrcc6bp1
XRCC6 binding protein 1
chr11_+_76904513 1.17 ENSMUST00000072633.3
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr19_+_44992127 1.05 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_+_7977640 0.79 ENSMUST00000171271.1
ENSMUST00000037811.6
ENSMUST00000037520.7
Apob
apolipoprotein B
chr3_+_154711125 0.70 ENSMUST00000051862.6
4922501L14Rik
RIKEN cDNA 4922501L14 gene
chr10_+_43524080 0.64 ENSMUST00000057649.6
Gm9803
predicted gene 9803
chr3_+_108186332 0.58 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1
adhesion molecule with Ig like domain 1
chr9_+_56937462 0.55 ENSMUST00000034827.8
Imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr2_+_3770673 0.47 ENSMUST00000177037.1
Fam107b
family with sequence similarity 107, member B
chr11_+_83409137 0.44 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chr11_+_83409655 0.35 ENSMUST00000175848.1
ENSMUST00000108140.3
Rasl10b
RAS-like, family 10, member B
chr5_+_92897981 0.30 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr4_+_128058962 0.30 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr10_-_92722356 0.25 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr17_+_37045963 0.22 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr17_+_37045980 0.20 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_105178765 0.19 ENSMUST00000106939.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr4_+_156331103 0.09 ENSMUST00000074107.6
ENSMUST00000096792.5
Vmn2r-ps159
vomeronasal 2, receptor, pseudogene 159
chr8_+_106683052 0.03 ENSMUST00000048359.4
Tango6
transport and golgi organization 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.3 3.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.3 1.8 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.2 3.9 GO:0051608 histamine transport(GO:0051608)
0.2 0.8 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.4 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.6 GO:0007413 axonal fasciculation(GO:0007413)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 5.2 GO:0015833 peptide transport(GO:0015833)
0.0 2.1 GO:0006457 protein folding(GO:0006457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 11.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
1.1 4.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.6 3.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.5 19.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.6 GO:0030519 snoRNP binding(GO:0030519)
0.2 1.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0035473 lipase binding(GO:0035473)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 5.2 GO:0015293 symporter activity(GO:0015293)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 4.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)