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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Rreb1

Z-value: 1.13

Motif logo

Transcription factors associated with Rreb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000039087.10 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rreb1mm10_v2_chr13_+_37778384_377784030.538.3e-04Click!

Activity profile of Rreb1 motif

Sorted Z-values of Rreb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_142576492 5.74 ENSMUST00000140716.1
H19 fetal liver mRNA
chr16_-_36408349 5.52 ENSMUST00000023619.6
stefin A2
chr9_-_109849440 4.19 ENSMUST00000112022.2
cathelicidin antimicrobial peptide
chr7_-_142578093 3.17 ENSMUST00000149974.1
ENSMUST00000152754.1
H19 fetal liver mRNA
chr7_-_142578139 3.14 ENSMUST00000136359.1
H19 fetal liver mRNA
chr5_-_122002340 2.67 ENSMUST00000134326.1
cut-like homeobox 2
chr17_+_29135056 2.28 ENSMUST00000087942.4
RAB44, member RAS oncogene family
chr4_+_44943727 2.04 ENSMUST00000154177.1
predicted gene 12678
chr8_+_57455898 1.77 ENSMUST00000034023.3
scrapie responsive gene 1
chr14_+_32321987 1.75 ENSMUST00000022480.7
oxoglutarate dehydrogenase-like
chr12_+_109545390 1.74 ENSMUST00000146701.1
maternally expressed 3
chr9_-_103480328 1.73 ENSMUST00000124310.2
beaded filament structural protein 2, phakinin
chr6_+_127887582 1.70 ENSMUST00000032501.4
tetraspanin 11
chr7_+_24897381 1.63 ENSMUST00000003469.7
CD79A antigen (immunoglobulin-associated alpha)
chrX_-_73659724 1.52 ENSMUST00000114473.1
ENSMUST00000002087.7
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr4_-_4138432 1.51 ENSMUST00000070375.7
preproenkephalin
chr5_+_76656512 1.49 ENSMUST00000086909.4
predicted gene 10430
chr14_+_69609068 1.41 ENSMUST00000022660.7
lysyl oxidase-like 2
chr6_+_72549652 1.40 ENSMUST00000134809.1
capping protein (actin filament), gelsolin-like
chr4_+_115059507 1.32 ENSMUST00000162489.1
T cell acute lymphocytic leukemia 1
chr14_+_55765956 1.30 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr4_+_41633286 1.30 ENSMUST00000119127.1
dynein, axonemal, intermediate chain 1
chr3_+_96181151 1.27 ENSMUST00000035371.8
synaptic vesicle glycoprotein 2 a
chr2_-_158229215 1.27 ENSMUST00000103121.3
ENSMUST00000169335.1
ENSMUST00000046944.5
RIKEN cDNA D630003M21 gene
chr9_-_67832325 1.26 ENSMUST00000054500.5
C2 calcium-dependent domain containing 4A
chr4_-_3938354 1.23 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr19_+_8591254 1.22 ENSMUST00000010251.3
ENSMUST00000170817.1
solute carrier family 22 (organic anion transporter), member 8
chr6_+_87778084 1.21 ENSMUST00000032133.3
glycoprotein 9 (platelet)
chr8_-_11008458 1.18 ENSMUST00000040514.6
insulin receptor substrate 2
chr5_+_122210134 1.16 ENSMUST00000100747.2
hydrogen voltage-gated channel 1
chr4_+_44300876 1.10 ENSMUST00000045607.5
maternal embryonic leucine zipper kinase
chr11_-_106314494 1.07 ENSMUST00000167143.1
CD79B antigen
chr11_-_94242701 1.04 ENSMUST00000061469.3
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr11_-_100411874 1.03 ENSMUST00000141840.1
leprecan-like 4
chr7_+_100495987 1.03 ENSMUST00000133044.1
uncoupling protein 2 (mitochondrial, proton carrier)
chrX_+_7919816 1.01 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr5_+_135674572 1.00 ENSMUST00000153515.1
P450 (cytochrome) oxidoreductase
chr17_+_43568096 0.97 ENSMUST00000167214.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr1_+_187608755 0.97 ENSMUST00000127489.1
estrogen-related receptor gamma
chr3_+_146149829 0.96 ENSMUST00000011152.7
mucolipin 2
chr4_+_136172367 0.94 ENSMUST00000061721.5
E2F transcription factor 2
chr13_+_76579670 0.94 ENSMUST00000126960.1
ENSMUST00000109583.2
multiple C2 domains, transmembrane 1
chr8_-_95294074 0.92 ENSMUST00000184103.1
cyclic nucleotide gated channel beta 1
chr8_+_120002720 0.89 ENSMUST00000108972.3
cysteine-rich secretory protein LCCL domain containing 2
chr11_-_103356324 0.89 ENSMUST00000136491.2
ENSMUST00000107023.2
Rho GTPase activating protein 27
chr6_+_145121727 0.88 ENSMUST00000032396.6
lymphoid-restricted membrane protein
chr10_+_78069351 0.88 ENSMUST00000105393.1
icos ligand
chr3_+_146150174 0.88 ENSMUST00000098524.4
mucolipin 2
chr3_+_51224447 0.87 ENSMUST00000023849.8
ENSMUST00000167780.1
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr3_-_89245159 0.86 ENSMUST00000090924.6
tripartite motif-containing 46
chr7_+_5056856 0.84 ENSMUST00000131368.1
ENSMUST00000123956.1
coiled-coil domain containing 106
chr12_-_112802646 0.80 ENSMUST00000124526.1
AHNAK nucleoprotein 2
chr18_-_21652362 0.80 ENSMUST00000049105.4
kelch-like 14
chr5_+_37047464 0.80 ENSMUST00000137019.1
janus kinase and microtubule interacting protein 1
chr9_+_119052863 0.78 ENSMUST00000131647.1
villin-like
chr19_-_4191035 0.78 ENSMUST00000045864.2
TBC1 domain family, member 10c
chr4_-_11965699 0.78 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chrX_-_73149450 0.78 ENSMUST00000080324.3
DNA segment, Chr X, Baylor 18
chr10_-_6980376 0.77 ENSMUST00000105617.1
interaction protein for cytohesin exchange factors 1
chrX_-_104671048 0.77 ENSMUST00000042070.5
zinc finger, DHHC domain containing 15
chr7_-_133123770 0.75 ENSMUST00000164896.1
ENSMUST00000171968.1
C-terminal binding protein 2
chr5_+_122100951 0.75 ENSMUST00000014080.6
ENSMUST00000111750.1
ENSMUST00000139213.1
ENSMUST00000111751.1
ENSMUST00000155612.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr19_-_6858179 0.75 ENSMUST00000113440.1
coiled-coil domain containing 88B
chr1_-_182019927 0.75 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
enabled homolog (Drosophila)
chr11_-_96005872 0.74 ENSMUST00000013559.2
insulin-like growth factor 2 mRNA binding protein 1
chr13_+_52596847 0.74 ENSMUST00000055087.6
spleen tyrosine kinase
chr2_-_125506385 0.74 ENSMUST00000028633.6
fibrillin 1
chrX_+_73117047 0.73 ENSMUST00000088459.2
predicted gene 14685
chr4_+_62480025 0.71 ENSMUST00000030088.5
ENSMUST00000107449.3
B-box and SPRY domain containing
chr11_+_3289880 0.69 ENSMUST00000110043.1
ENSMUST00000094471.3
POZ (BTB) and AT hook containing zinc finger 1
chr7_+_25627604 0.69 ENSMUST00000076034.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr11_-_59029509 0.69 ENSMUST00000127937.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr17_+_47593516 0.69 ENSMUST00000182874.1
cyclin D3
chr2_+_158306493 0.69 ENSMUST00000016168.2
ENSMUST00000109491.1
lipopolysaccharide binding protein
chr2_+_145167706 0.69 ENSMUST00000110007.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr16_-_32165454 0.69 ENSMUST00000115163.3
ENSMUST00000144345.1
ENSMUST00000143682.1
ENSMUST00000115165.3
ENSMUST00000099991.4
ENSMUST00000130410.1
negative regulator of reactive oxygen species
chr2_+_136057927 0.68 ENSMUST00000057503.6
lysosomal-associated membrane protein family, member 5
chr10_-_7473361 0.68 ENSMUST00000169796.2
ENSMUST00000177585.1
UL16 binding protein 1
chr6_+_48860339 0.68 ENSMUST00000101425.3
predicted gene 7932
chr1_+_135783065 0.67 ENSMUST00000132795.1
troponin I, skeletal, slow 1
chr9_+_119052770 0.67 ENSMUST00000051386.6
ENSMUST00000074734.6
villin-like
chr4_+_130915949 0.67 ENSMUST00000030316.6
lysosomal-associated protein transmembrane 5
chr9_+_110333402 0.67 ENSMUST00000133114.1
ENSMUST00000125759.1
SREBF chaperone
chr19_-_56389877 0.66 ENSMUST00000166203.1
ENSMUST00000167239.1
ENSMUST00000040711.8
ENSMUST00000095947.4
ENSMUST00000073536.6
nebulin-related anchoring protein
chr18_-_68429235 0.65 ENSMUST00000052347.6
melanocortin 2 receptor
chr5_+_113490447 0.65 ENSMUST00000094452.3
WSC domain containing 2
chr2_+_103957976 0.64 ENSMUST00000156813.1
ENSMUST00000170926.1
LIM domain only 2
chr15_-_78529617 0.64 ENSMUST00000023075.8
C1q and tumor necrosis factor related protein 6
chr8_+_25911670 0.64 ENSMUST00000120653.1
ENSMUST00000126226.1
potassium channel, subfamily U, member 1
chr15_-_78855517 0.63 ENSMUST00000044584.4
lectin, galactose-binding, soluble 2
chr14_+_70077375 0.63 ENSMUST00000035908.1
early growth response 3
chr6_+_72549430 0.62 ENSMUST00000155705.1
capping protein (actin filament), gelsolin-like
chr7_+_24862193 0.62 ENSMUST00000052897.4
ENSMUST00000170837.2
predicted pseudogene 9844
predicted pseudogene 9844
chr17_+_37002610 0.61 ENSMUST00000173921.1
ENSMUST00000172580.1
zinc finger protein 57
chr3_+_88621102 0.60 ENSMUST00000029694.7
ENSMUST00000176804.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr9_-_32542861 0.60 ENSMUST00000183767.1
Friend leukemia integration 1
chr1_-_72874877 0.60 ENSMUST00000027377.8
insulin-like growth factor binding protein 5
chr3_-_89245005 0.59 ENSMUST00000107464.1
tripartite motif-containing 46
chr5_+_122209729 0.59 ENSMUST00000072602.7
ENSMUST00000143560.1
hydrogen voltage-gated channel 1
chr18_-_47333311 0.58 ENSMUST00000126684.1
ENSMUST00000156422.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr15_+_80133114 0.58 ENSMUST00000023050.7
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr7_-_126594941 0.58 ENSMUST00000058429.5
interleukin 27
chr19_-_4283033 0.58 ENSMUST00000167215.1
ENSMUST00000056888.6
ankyrin repeat domain 13 family, member D
chr6_+_141249161 0.57 ENSMUST00000043259.7
phosphodiesterase 3A, cGMP inhibited
chr5_-_111761697 0.57 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
RIKEN cDNA E130006D01 gene
chr18_+_36679575 0.56 ENSMUST00000050476.4
ENSMUST00000036158.6
solute carrier family 35, member A4
chr17_+_47593444 0.56 ENSMUST00000182209.1
cyclin D3
chrX_-_57338598 0.56 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr14_-_34201604 0.55 ENSMUST00000096019.2
G protein regulated inducer of neurite outgrowth 2
chr2_+_147364989 0.55 ENSMUST00000109968.2
paired box gene 1
chr7_+_43781054 0.55 ENSMUST00000014058.9
kallikrein related-peptidase 10
chr9_+_110333276 0.54 ENSMUST00000125823.1
ENSMUST00000131328.1
SREBF chaperone
chr6_-_126698192 0.54 ENSMUST00000060972.3
potassium voltage-gated channel, shaker-related subfamily, member 5
chr15_-_74636241 0.53 ENSMUST00000023271.1
maestro heat-like repeat family member 4
chr18_+_46850034 0.53 ENSMUST00000025358.2
RIKEN cDNA 4833403I15 gene
chr11_-_114960417 0.53 ENSMUST00000092466.5
ENSMUST00000061637.3
CD300C antigen
chr13_-_98206151 0.53 ENSMUST00000109426.1
Rho guanine nucleotide exchange factor (GEF) 28
chr11_+_77765588 0.53 ENSMUST00000164315.1
myosin XVIIIA
chrX_-_48034842 0.52 ENSMUST00000039026.7
apelin
chr5_+_140735526 0.51 ENSMUST00000120630.2
archaelysin family metallopeptidase 1
chr6_+_72549252 0.51 ENSMUST00000114071.1
capping protein (actin filament), gelsolin-like
chr6_+_89140992 0.51 ENSMUST00000162900.1
ENSMUST00000161362.1
ENSMUST00000160361.1
ENSMUST00000101176.3
predicted gene 1965
predicted gene 1965
chr8_+_69808672 0.50 ENSMUST00000036074.8
ENSMUST00000123453.1
Gem-interacting protein
chr11_-_34208085 0.50 ENSMUST00000060271.2
forkhead box I1
chr6_+_29396665 0.49 ENSMUST00000096084.5
coiled-coil domain containing 136
chr17_+_35077080 0.49 ENSMUST00000172959.1
lymphocyte antigen 6 complex, locus G6E
chr6_+_17307040 0.49 ENSMUST00000123439.1
caveolin 1, caveolae protein
chr4_-_134012381 0.49 ENSMUST00000176113.1
lin-28 homolog A (C. elegans)
chr2_+_14873656 0.48 ENSMUST00000114718.1
ENSMUST00000114719.1
calcium channel, voltage-dependent, beta 2 subunit
chr5_-_89883321 0.48 ENSMUST00000163159.1
ENSMUST00000061427.5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
chr9_-_8134294 0.47 ENSMUST00000037397.6
cDNA sequence AK129341
chr1_-_37719782 0.47 ENSMUST00000160589.1
RIKEN cDNA 2010300C02 gene
chr7_+_90426312 0.46 ENSMUST00000061391.7
coiled-coil domain containing 89
chr17_+_37002574 0.46 ENSMUST00000173588.1
zinc finger protein 57
chr4_-_58206596 0.46 ENSMUST00000042850.8
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr7_-_6155939 0.45 ENSMUST00000094870.1
zinc finger protein 787
chr8_+_57320975 0.45 ENSMUST00000040104.3
heart and neural crest derivatives expressed transcript 2
chr7_+_127777095 0.44 ENSMUST00000144406.1
SET domain containing 1A
chr11_-_98983016 0.44 ENSMUST00000062931.1
gap junction protein, delta 3
chr11_+_116198853 0.43 ENSMUST00000021130.6
TEN1 telomerase capping complex subunit
chr3_-_32616479 0.43 ENSMUST00000108234.1
ENSMUST00000155737.1
guanine nucleotide binding protein (G protein), beta 4
chr3_-_89245829 0.42 ENSMUST00000041022.8
tripartite motif-containing 46
chr2_-_45113255 0.42 ENSMUST00000068415.4
ENSMUST00000127520.1
zinc finger E-box binding homeobox 2
chr17_+_37002510 0.42 ENSMUST00000069250.7
zinc finger protein 57
chr7_-_98178254 0.42 ENSMUST00000040971.7
calpain 5
chr7_+_73391160 0.42 ENSMUST00000128471.1
RGM domain family, member A
chr19_+_10525244 0.42 ENSMUST00000038379.3
cleavage and polyadenylation specific factor 7
chr2_-_163417092 0.42 ENSMUST00000127038.1
oxidative stress responsive serine rich 1
chr19_+_38395980 0.41 ENSMUST00000054098.2
solute carrier family 35, member G1
chr2_-_9878580 0.41 ENSMUST00000102976.3
GATA binding protein 3
chr5_+_135994796 0.41 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
deltex 2 homolog (Drosophila)
chr2_-_31116289 0.41 ENSMUST00000149196.1
formin binding protein 1
chr6_-_92481343 0.41 ENSMUST00000113445.1
prickle homolog 2 (Drosophila)
chr6_+_29396576 0.40 ENSMUST00000115275.1
coiled-coil domain containing 136
chr1_+_171214013 0.40 ENSMUST00000111328.1
nuclear receptor subfamily 1, group I, member 3
chr3_+_159839729 0.40 ENSMUST00000068952.5
wntless homolog (Drosophila)
chr9_-_66919646 0.39 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr5_-_73632421 0.39 ENSMUST00000087177.2
leucine rich repeat containing 66
chr17_+_37002482 0.39 ENSMUST00000172527.1
zinc finger protein 57
chr3_-_125938537 0.39 ENSMUST00000057944.7
UDP galactosyltransferase 8A
chr4_-_141598206 0.39 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
filamin binding LIM protein 1
chr3_-_96594128 0.38 ENSMUST00000145001.1
ENSMUST00000091924.3
polymerase (RNA) III (DNA directed) polypeptide G like
chr14_+_70555900 0.38 ENSMUST00000163060.1
hairless
chr5_+_114707760 0.38 ENSMUST00000094441.4
trichoplein, keratin filament binding
chr7_+_139214661 0.38 ENSMUST00000135509.1
leucine rich repeat containing 27
chr11_+_121204420 0.38 ENSMUST00000038831.8
ENSMUST00000106117.1
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr6_+_118066356 0.37 ENSMUST00000164960.1
RasGEF domain family, member 1A
chr5_+_34999111 0.37 ENSMUST00000114283.1
regulator of G-protein signaling 12
chr2_+_74681991 0.37 ENSMUST00000142312.1
homeobox D11
chr19_+_24673998 0.37 ENSMUST00000057243.4
transmembrane protein 252
chr3_-_88621061 0.37 ENSMUST00000177314.1
predicted gene 20652
chrX_-_51205773 0.37 ENSMUST00000114875.1
muscleblind-like 3 (Drosophila)
chr14_+_65806066 0.36 ENSMUST00000139644.1
PDZ binding kinase
chr7_+_5056706 0.36 ENSMUST00000144802.1
coiled-coil domain containing 106
chr8_+_93810832 0.36 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr4_-_41098174 0.36 ENSMUST00000055327.7
aquaporin 3
chr6_-_89362581 0.36 ENSMUST00000163139.1
plexin A1
chr10_+_68723723 0.35 ENSMUST00000080995.6
transmembrane protein 26
chr9_-_37147257 0.35 ENSMUST00000039674.5
ENSMUST00000080754.5
Pbx/knotted 1 homeobox 2
chr19_+_27217011 0.35 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr19_+_27217357 0.35 ENSMUST00000047645.6
ENSMUST00000167487.1
very low density lipoprotein receptor
chr4_+_43441939 0.35 ENSMUST00000060864.6
testis specific protein kinase 1
chr17_+_29549783 0.34 ENSMUST00000048677.7
TBC1 domain family, member 22B
chr5_-_120588613 0.34 ENSMUST00000046426.8
two pore channel 1
chr4_-_117929726 0.34 ENSMUST00000070816.2
artemin
chr8_+_15057646 0.34 ENSMUST00000033842.3
myomesin 2
chr10_+_80179482 0.34 ENSMUST00000003154.6
ephrin A2
chr17_+_35823509 0.34 ENSMUST00000173493.1
ENSMUST00000173147.1
ENSMUST00000172846.1
flotillin 1
chr7_+_131548755 0.34 ENSMUST00000183219.1
H6 homeobox 2
chr11_-_70229677 0.33 ENSMUST00000153449.1
ENSMUST00000000326.5
B cell CLL/lymphoma 6, member B
chr9_-_90255927 0.33 ENSMUST00000144646.1
TBC1 domain family, member 2B
chr11_-_50827681 0.33 ENSMUST00000109135.2
zinc finger protein 354C
chr18_+_42053648 0.33 ENSMUST00000072008.4
SH3 domain containing ring finger 2
chr8_-_87959560 0.33 ENSMUST00000109655.2
zinc finger protein 423
chr6_+_48739039 0.33 ENSMUST00000054368.4
ENSMUST00000140054.1
GTPase, IMAP family member 1
chr19_+_21778325 0.32 ENSMUST00000096194.2
ENSMUST00000025663.6
transmembrane protein 2
chr5_-_114690906 0.32 ENSMUST00000112212.1
ENSMUST00000112214.1
glycolipid transfer protein
chr2_-_65567465 0.32 ENSMUST00000066432.5
sodium channel, voltage-gated, type III, alpha
chr16_+_90826719 0.32 ENSMUST00000099548.2
eva-1 homolog C (C. elegans)
chr13_+_37825975 0.31 ENSMUST00000138043.1
ras responsive element binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Rreb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.4 1.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.4 1.2 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 0.9 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.5 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.3 4.3 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.2 1.0 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.2 0.7 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.2 0.4 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.2 0.7 GO:0045425 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
0.2 0.7 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 0.5 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 0.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 0.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.8 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 1.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.2 0.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.5 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 1.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.7 GO:0034436 glycoprotein transport(GO:0034436)
0.1 2.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.9 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 1.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.3 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.4 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.3 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 0.2 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.1 1.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 2.3 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.2 GO:0010748 negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 1.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0090095 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.6 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 2.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.5 GO:0098914 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.3 GO:0061153 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.5 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.3 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.1 GO:0070307 lens fiber cell development(GO:0070307)
0.1 2.0 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 3.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.2 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 1.2 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.6 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.5 GO:0051693 actin filament capping(GO:0051693)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110)
0.1 0.8 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.2 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.2 GO:0072137 cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:1902617 response to fluoride(GO:1902617)
0.1 0.3 GO:0015867 ATP transport(GO:0015867)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0032329 serine transport(GO:0032329)
0.0 0.2 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.6 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078) regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 2.7 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.8 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.3 GO:0015879 carnitine transport(GO:0015879)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.2 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.0 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.0 3.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.0 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.4 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.9 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0019815 B cell receptor complex(GO:0019815)
0.4 1.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.4 1.5 GO:0032280 symmetric synapse(GO:0032280)
0.4 1.9 GO:1990769 proximal neuron projection(GO:1990769)
0.3 4.2 GO:0042581 specific granule(GO:0042581)
0.2 2.5 GO:0090543 Flemming body(GO:0090543)
0.2 0.5 GO:0046691 intracellular canaliculus(GO:0046691)
0.2 1.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 10.6 GO:0005844 polysome(GO:0005844)
0.1 0.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.7 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 2.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0045179 apical cortex(GO:0045179) ciliary transition fiber(GO:0097539)
0.0 0.2 GO:1990462 omegasome(GO:1990462)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 1.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.0 GO:0008941 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 0.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 1.5 GO:0001515 opioid peptide activity(GO:0001515)
0.2 0.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.2 0.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 1.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:1990188 euchromatin binding(GO:1990188)
0.1 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 1.2 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 0.4 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 1.0 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 4.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939) alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.0 2.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0008147 structural constituent of bone(GO:0008147) hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)
0.0 4.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters