avrg: GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Runx1 Links Ensembl NCBI MGI UniProt	ENSMUSG00000022952.10	runt related transcription factor 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Runx1	mm10_v2_chr16_-_92826004_92826080	0.87	5.0e-12	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_87793470 Show fit	15.27	ENSMUST00000020779.4	Mpo Links Ensembl NCBI MGI UniProt Show fit	myeloperoxidase
chr11_+_87793722 Show fit	14.45	ENSMUST00000143021.2	Mpo Links Ensembl NCBI MGI UniProt Show fit	myeloperoxidase
chr16_-_92826004 Show fit	13.22	ENSMUST00000023673.7	Runx1 Links Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 1
chr2_-_28084877 Show fit	10.65	ENSMUST00000028179.8 ENSMUST00000117486.1 ENSMUST00000135472.1	Fcnb Links Ensembl NCBI MGI UniProt Show fit	ficolin B
chr4_-_46404224 Show fit	10.13	ENSMUST00000107764.2	Hemgn Links Ensembl NCBI MGI UniProt Show fit	hemogen
chr15_-_103255433 Show fit	8.50	ENSMUST00000075192.6	Nfe2 Links Ensembl NCBI MGI UniProt Show fit	nuclear factor, erythroid derived 2
chr3_-_59101810 Show fit	7.26	ENSMUST00000085040.4	Gpr171 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 171
chr1_+_40515362 Show fit	6.96	ENSMUST00000027237.5	Il18rap Links Ensembl NCBI MGI UniProt Show fit	interleukin 18 receptor accessory protein
chr5_-_107726017 Show fit	6.87	ENSMUST00000159263.2	Gfi1 Links Ensembl NCBI MGI UniProt Show fit	growth factor independent 1
chr2_+_164948219 Show fit	6.76	ENSMUST00000017881.2	Mmp9 Links Ensembl NCBI MGI UniProt Show fit	matrix metallopeptidase 9
chr13_-_113100971 Show fit	6.43	ENSMUST00000023897.5	Gzma Links Ensembl NCBI MGI UniProt Show fit	granzyme A
chr7_+_143005046 Show fit	6.02	ENSMUST00000009396.6	Tspan32 Links Ensembl NCBI MGI UniProt Show fit	tetraspanin 32
chr7_-_127137807 Show fit	5.84	ENSMUST00000049931.5	Spn Links Ensembl NCBI MGI UniProt Show fit	sialophorin
chr14_+_56042123 Show fit	5.78	ENSMUST00000015576.4	Mcpt2 Links Ensembl NCBI MGI UniProt Show fit	mast cell protease 2
chr7_+_44572370 Show fit	5.63	ENSMUST00000002274.8	Napsa Links Ensembl NCBI MGI UniProt Show fit	napsin A aspartic peptidase
chr7_+_24370255 Show fit	5.49	ENSMUST00000171904.1	Kcnn4 Links Ensembl NCBI MGI UniProt Show fit	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr13_+_76579670 Show fit	5.31	ENSMUST00000126960.1 ENSMUST00000109583.2	Mctp1 Links Ensembl NCBI MGI UniProt Show fit	multiple C2 domains, transmembrane 1
chr15_-_66801577 Show fit	5.25	ENSMUST00000168589.1	Sla Links Ensembl NCBI MGI UniProt Show fit	src-like adaptor
chr2_+_172393900 Show fit	5.10	ENSMUST00000109136.2	Cass4 Links Ensembl NCBI MGI UniProt Show fit	Cas scaffolding protein family member 4
chr17_+_31208049 Show fit	5.00	ENSMUST00000173776.1	Ubash3a Links Ensembl NCBI MGI UniProt Show fit	ubiquitin associated and SH3 domain containing, A
chrX_-_8090442 Show fit	4.34	ENSMUST00000033505.6	Was Links Ensembl NCBI MGI UniProt Show fit	Wiskott-Aldrich syndrome homolog (human)
chr18_-_35649349 Show fit	4.32	ENSMUST00000025211.4	Mzb1 Links Ensembl NCBI MGI UniProt Show fit	marginal zone B and B1 cell-specific protein 1
chr2_-_58160495 Show fit	4.29	ENSMUST00000028175.6	Cytip Links Ensembl NCBI MGI UniProt Show fit	cytohesin 1 interacting protein
chr4_+_135120640 Show fit	3.89	ENSMUST00000056977.7	Runx3 Links Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 3
chr3_+_103860265 Show fit	3.89	ENSMUST00000029433.7	Ptpn22 Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr8_+_105690906 Show fit	3.79	ENSMUST00000062574.6	Rltpr Links Ensembl NCBI MGI UniProt Show fit	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr17_+_47596061 Show fit	3.62	ENSMUST00000182539.1	Ccnd3 Links Ensembl NCBI MGI UniProt Show fit	cyclin D3
chr17_+_12119274 Show fit	3.25	ENSMUST00000024594.2	Agpat4 Links Ensembl NCBI MGI UniProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr7_-_43533171 Show fit	3.19	ENSMUST00000004728.5 ENSMUST00000039861.5	Cd33 Links Ensembl NCBI MGI UniProt Show fit	CD33 antigen
chr2_-_26021679 Show fit	3.07	ENSMUST00000036509.7	Ubac1 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin associated domain containing 1
chr11_-_83649349 Show fit	3.03	ENSMUST00000001008.5	Ccl3 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 3
chrX_-_57338598 Show fit	3.01	ENSMUST00000033468.4 ENSMUST00000114736.1	Arhgef6 Links Ensembl NCBI MGI UniProt Show fit	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_-_133872997 Show fit	2.97	ENSMUST00000137486.2	Rps6ka1 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 1
chr2_-_26021532 Show fit	2.96	ENSMUST00000136750.1	Ubac1 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin associated domain containing 1
chr12_+_85686648 Show fit	2.95	ENSMUST00000040536.5	Batf Links Ensembl NCBI MGI UniProt Show fit	basic leucine zipper transcription factor, ATF-like
chr14_-_56262233 Show fit	2.87	ENSMUST00000015581.4	Gzmb Links Ensembl NCBI MGI UniProt Show fit	granzyme B
chr7_-_25132473 Show fit	2.84	ENSMUST00000108418.4 ENSMUST00000108415.3 ENSMUST00000098679.3 ENSMUST00000175774.2 ENSMUST00000108417.3 ENSMUST00000108416.3 ENSMUST00000108414.1 ENSMUST00000108413.1 ENSMUST00000176408.1	Pou2f2 Links Ensembl NCBI MGI UniProt Show fit	POU domain, class 2, transcription factor 2
chr11_+_69966896 Show fit	2.69	ENSMUST00000151515.1	Cldn7 Links Ensembl NCBI MGI UniProt Show fit	claudin 7
chr8_-_11008458 Show fit	2.67	ENSMUST00000040514.6	Irs2 Links Ensembl NCBI MGI UniProt Show fit	insulin receptor substrate 2
chr3_+_96181151 Show fit	2.54	ENSMUST00000035371.8	Sv2a Links Ensembl NCBI MGI UniProt Show fit	synaptic vesicle glycoprotein 2 a
chr17_+_33638056 Show fit	2.48	ENSMUST00000052079.7	Pram1 Links Ensembl NCBI MGI UniProt Show fit	PML-RAR alpha-regulated adaptor molecule 1
chr13_+_76579681 Show fit	2.41	ENSMUST00000109589.2	Mctp1 Links Ensembl NCBI MGI UniProt Show fit	multiple C2 domains, transmembrane 1
chr6_-_136941494 Show fit	2.38	ENSMUST00000111892.1	Arhgdib Links Ensembl NCBI MGI UniProt Show fit	Rho, GDP dissociation inhibitor (GDI) beta
chr15_-_9529868 Show fit	2.38	ENSMUST00000003981.4	Il7r Links Ensembl NCBI MGI UniProt Show fit	interleukin 7 receptor
chr11_-_79530569 Show fit	2.35	ENSMUST00000103236.3 ENSMUST00000170799.1 ENSMUST00000170422.2	Evi2a Links Ensembl NCBI MGI UniProt Show fit Evi2b Links Ensembl NCBI MGI UniProt Show fit	ecotropic viral integration site 2a ecotropic viral integration site 2b
chrX_+_159697308 Show fit	2.34	ENSMUST00000123433.1	Sh3kbp1 Links Ensembl NCBI MGI UniProt Show fit	SH3-domain kinase binding protein 1
chr14_+_70774304 Show fit	2.25	ENSMUST00000022698.7	Dok2 Links Ensembl NCBI MGI UniProt Show fit	docking protein 2
chr18_-_62179948 Show fit	2.23	ENSMUST00000053640.3	Adrb2 Links Ensembl NCBI MGI UniProt Show fit	adrenergic receptor, beta 2
chr6_-_136941694 Show fit	2.23	ENSMUST00000032344.5	Arhgdib Links Ensembl NCBI MGI UniProt Show fit	Rho, GDP dissociation inhibitor (GDI) beta
chr2_+_153938218 Show fit	2.23	ENSMUST00000109757.1	Bpifb4 Links Ensembl NCBI MGI UniProt Show fit	BPI fold containing family B, member 4
chr15_-_34356421 Show fit	2.19	ENSMUST00000179647.1	9430069I07Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 9430069I07 gene
chr11_-_69895523 Show fit	2.10	ENSMUST00000001631.6	Acap1 Links Ensembl NCBI MGI UniProt Show fit	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr2_-_119760295 Show fit	2.08	ENSMUST00000082130.6 ENSMUST00000028759.6	Ltk Links Ensembl NCBI MGI UniProt Show fit	leukocyte tyrosine kinase
chr15_-_98607611 Show fit	2.06	ENSMUST00000096224.4	Adcy6 Links Ensembl NCBI MGI UniProt Show fit	adenylate cyclase 6
chr10_+_118441044 Show fit	2.05	ENSMUST00000068592.3	Ifng Links Ensembl NCBI MGI UniProt Show fit	interferon gamma
chr2_-_73485733 Show fit	2.00	ENSMUST00000102680.1	Wipf1 Links Ensembl NCBI MGI UniProt Show fit	WAS/WASL interacting protein family, member 1
chr11_-_4594750 Show fit	1.96	ENSMUST00000109943.3	Mtmr3 Links Ensembl NCBI MGI UniProt Show fit	myotubularin related protein 3
chr7_-_133709051 Show fit	1.94	ENSMUST00000124759.1 ENSMUST00000106144.1	Uros Links Ensembl NCBI MGI UniProt Show fit	uroporphyrinogen III synthase
chr7_-_115824699 Show fit	1.94	ENSMUST00000169129.1	Sox6 Links Ensembl NCBI MGI UniProt Show fit	SRY-box containing gene 6
chr16_-_58718724 Show fit	1.86	ENSMUST00000089318.3	Gpr15 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 15
chr4_-_129573637 Show fit	1.81	ENSMUST00000102596.1	Lck Links Ensembl NCBI MGI UniProt Show fit	lymphocyte protein tyrosine kinase
chr4_-_70410422 Show fit	1.78	ENSMUST00000144099.1	Cdk5rap2 Links Ensembl NCBI MGI UniProt Show fit	CDK5 regulatory subunit associated protein 2
chr2_-_73486456 Show fit	1.72	ENSMUST00000141264.1	Wipf1 Links Ensembl NCBI MGI UniProt Show fit	WAS/WASL interacting protein family, member 1
chr7_-_25675047 Show fit	1.69	ENSMUST00000108404.1 ENSMUST00000108405.1 ENSMUST00000079439.3	Tmem91 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 91
chr18_+_62180119 Show fit	1.68	ENSMUST00000067743.1	Gm9949 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 9949
chr15_+_9436028 Show fit	1.58	ENSMUST00000042360.3	Capsl Links Ensembl NCBI MGI UniProt Show fit	calcyphosine-like
chr11_-_101095367 Show fit	1.54	ENSMUST00000019447.8	Psmc3ip Links Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr12_-_112860886 Show fit	1.51	ENSMUST00000021729.7	Gpr132 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 132
chr5_+_139406387 Show fit	1.48	ENSMUST00000052176.8	C130050O18Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA C130050O18 gene
chr17_+_75178797 Show fit	1.48	ENSMUST00000112516.1 ENSMUST00000135447.1	Ltbp1 Links Ensembl NCBI MGI UniProt Show fit	latent transforming growth factor beta binding protein 1
chr3_-_96814518 Show fit	1.46	ENSMUST00000047702.7	Cd160 Links Ensembl NCBI MGI UniProt Show fit	CD160 antigen
chr15_-_97844254 Show fit	1.44	ENSMUST00000119670.1 ENSMUST00000116409.2	Hdac7 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 7
chr15_-_97844164 Show fit	1.43	ENSMUST00000120683.1	Hdac7 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 7
chr7_-_133708958 Show fit	1.38	ENSMUST00000106146.1	Uros Links Ensembl NCBI MGI UniProt Show fit	uroporphyrinogen III synthase
chr7_+_126584937 Show fit	1.34	ENSMUST00000039522.6	Apobr Links Ensembl NCBI MGI UniProt Show fit	apolipoprotein B receptor
chr17_+_75178911 Show fit	1.29	ENSMUST00000112514.1	Ltbp1 Links Ensembl NCBI MGI UniProt Show fit	latent transforming growth factor beta binding protein 1
chr10_-_40302186 Show fit	1.28	ENSMUST00000099945.4	Amd1 Links Ensembl NCBI MGI UniProt Show fit	S-adenosylmethionine decarboxylase 1
chr1_+_171388954 Show fit	1.28	ENSMUST00000056449.8	Arhgap30 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 30
chr7_-_133709069 Show fit	1.27	ENSMUST00000106145.3	Uros Links Ensembl NCBI MGI UniProt Show fit	uroporphyrinogen III synthase
chr8_+_109705549 Show fit	1.27	ENSMUST00000034163.8	Zfp821 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 821
chr2_-_32741016 Show fit	1.24	ENSMUST00000009695.2	6330409D20Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 6330409D20 gene
chr2_+_153918391 Show fit	1.24	ENSMUST00000109760.1	Bpifb3 Links Ensembl NCBI MGI UniProt Show fit	BPI fold containing family B, member 3
chr5_+_140607334 Show fit	1.23	ENSMUST00000031555.1	Lfng Links Ensembl NCBI MGI UniProt Show fit	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_-_48034842 Show fit	1.23	ENSMUST00000039026.7	Apln Links Ensembl NCBI MGI UniProt Show fit	apelin
chr8_+_94667082 Show fit	1.20	ENSMUST00000109527.4	Arl2bp Links Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor-like 2 binding protein
chr1_-_138175126 Show fit	1.17	ENSMUST00000183301.1	Ptprc Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, C
chr19_+_5568002 Show fit	1.16	ENSMUST00000096318.3	Ap5b1 Links Ensembl NCBI MGI UniProt Show fit	adaptor-related protein complex 5, beta 1 subunit
chr1_-_138175283 Show fit	1.14	ENSMUST00000182755.1 ENSMUST00000183262.1 ENSMUST00000027645.7 ENSMUST00000112036.2 ENSMUST00000182283.1	Ptprc Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, C
chr5_+_48242549 Show fit	1.12	ENSMUST00000172493.1	Slit2 Links Ensembl NCBI MGI UniProt Show fit	slit homolog 2 (Drosophila)
chr9_-_32928928 Show fit	1.11	ENSMUST00000185169.1	RP24-308I2.1 Links Ensembl NCBI MGI UniProt Show fit	RP24-308I2.1
chrX_+_56786527 Show fit	1.10	ENSMUST00000144600.1	Fhl1 Links Ensembl NCBI MGI UniProt Show fit	four and a half LIM domains 1
chr1_-_138175238 Show fit	1.09	ENSMUST00000182536.1	Ptprc Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, C
chr4_-_41275091 Show fit	1.09	ENSMUST00000030143.6 ENSMUST00000108068.1	Ubap2 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-associated protein 2
chr2_+_172393794 Show fit	1.07	ENSMUST00000099061.2 ENSMUST00000103073.2	Cass4 Links Ensembl NCBI MGI UniProt Show fit	Cas scaffolding protein family member 4
chr3_-_86142684 Show fit	1.04	ENSMUST00000029722.6	Rps3a1 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S3A1
chr15_+_80711292 Show fit	1.01	ENSMUST00000067689.7	Tnrc6b Links Ensembl NCBI MGI UniProt Show fit	trinucleotide repeat containing 6b
chr16_-_95586585 Show fit	0.93	ENSMUST00000077773.6	Erg Links Ensembl NCBI MGI UniProt Show fit	avian erythroblastosis virus E-26 (v-ets) oncogene related
chr16_+_18877037 Show fit	0.91	ENSMUST00000120532.1 ENSMUST00000004222.7	Hira Links Ensembl NCBI MGI UniProt Show fit	histone cell cycle regulation defective homolog A (S. cerevisiae)
chr11_-_110168073 Show fit	0.87	ENSMUST00000044850.3	Abca9 Links Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 9
chr10_-_95673451 Show fit	0.87	ENSMUST00000099328.1	Anapc15-ps Links Ensembl NCBI MGI UniProt Show fit	anaphase prompoting complex C subunit 15, pseudogene
chr9_-_107770945 Show fit	0.85	ENSMUST00000183248.1 ENSMUST00000182022.1 ENSMUST00000035199.6 ENSMUST00000182659.1	Rbm5 Links Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein 5
chr11_-_100121558 Show fit	0.83	ENSMUST00000007275.2	Krt13 Links Ensembl NCBI MGI UniProt Show fit	keratin 13
chr15_-_78493607 Show fit	0.83	ENSMUST00000163494.1	Il2rb Links Ensembl NCBI MGI UniProt Show fit	interleukin 2 receptor, beta chain
chr4_-_6990774 Show fit	0.83	ENSMUST00000039987.3	Tox Links Ensembl NCBI MGI UniProt Show fit	thymocyte selection-associated high mobility group box
chr1_-_161788489 Show fit	0.82	ENSMUST00000000834.2	Fasl Links Ensembl NCBI MGI UniProt Show fit	Fas ligand (TNF superfamily, member 6)
chr6_+_136518820 Show fit	0.82	ENSMUST00000032335.6	Atf7ip Links Ensembl NCBI MGI UniProt Show fit	activating transcription factor 7 interacting protein
chr4_+_133176336 Show fit	0.75	ENSMUST00000105912.1	Wasf2 Links Ensembl NCBI MGI UniProt Show fit	WAS protein family, member 2
chr1_+_160044564 Show fit	0.72	ENSMUST00000168359.1	4930523C07Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4930523C07 gene
chr4_-_152038568 Show fit	0.71	ENSMUST00000030792.1	Tas1r1 Links Ensembl NCBI MGI UniProt Show fit	taste receptor, type 1, member 1
chrX_-_12160355 Show fit	0.67	ENSMUST00000043441.6	Bcor Links Ensembl NCBI MGI UniProt Show fit	BCL6 interacting corepressor
chr1_-_164935522 Show fit	0.59	ENSMUST00000027860.7	Xcl1 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C motif) ligand 1
chr16_+_32271468 Show fit	0.57	ENSMUST00000093183.3	Smco1 Links Ensembl NCBI MGI UniProt Show fit	single-pass membrane protein with coiled-coil domains 1
chr6_-_38637220 Show fit	0.55	ENSMUST00000096030.3	Klrg2 Links Ensembl NCBI MGI UniProt Show fit	killer cell lectin-like receptor subfamily G, member 2
chr10_-_127288999 Show fit	0.54	ENSMUST00000119078.1	Mbd6 Links Ensembl NCBI MGI UniProt Show fit	methyl-CpG binding domain protein 6
chr14_-_121915774 Show fit	0.51	ENSMUST00000055475.7	Gpr18 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 18
chr1_+_172956768 Show fit	0.48	ENSMUST00000038432.4	Olfr16 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 16
chr9_+_113812547 Show fit	0.45	ENSMUST00000166734.2 ENSMUST00000111838.2 ENSMUST00000163895.2	Clasp2 Links Ensembl NCBI MGI UniProt Show fit	CLIP associating protein 2
chr7_-_132852606 Show fit	0.45	ENSMUST00000120425.1	Mettl10 Links Ensembl NCBI MGI UniProt Show fit	methyltransferase like 10
chr9_+_108479849 Show fit	0.41	ENSMUST00000065014.4	Lamb2 Links Ensembl NCBI MGI UniProt Show fit	laminin, beta 2
chr12_+_116077720 Show fit	0.41	ENSMUST00000011315.3	Vipr2 Links Ensembl NCBI MGI UniProt Show fit	vasoactive intestinal peptide receptor 2
chr5_+_87808082 Show fit	0.41	ENSMUST00000072539.5 ENSMUST00000113279.1 ENSMUST00000101057.3	Csn1s2b Links Ensembl NCBI MGI UniProt Show fit	casein alpha s2-like B
chr10_-_127288851 Show fit	0.40	ENSMUST00000156208.1 ENSMUST00000026476.6	Mbd6 Links Ensembl NCBI MGI UniProt Show fit	methyl-CpG binding domain protein 6
chr2_-_20943413 Show fit	0.40	ENSMUST00000140230.1	Arhgap21 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 21
chr1_+_36307727 Show fit	0.34	ENSMUST00000126413.1	Arid5a Links Ensembl NCBI MGI UniProt Show fit	AT rich interactive domain 5A (MRF1-like)
chr2_+_37516618 Show fit	0.33	ENSMUST00000065441.6	Gpr21 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 21
chr11_+_75531690 Show fit	0.30	ENSMUST00000149727.1 ENSMUST00000042561.7 ENSMUST00000108433.1 ENSMUST00000143035.1	Slc43a2 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 43, member 2
chrX_-_20950597 Show fit	0.29	ENSMUST00000009550.7	Elk1 Links Ensembl NCBI MGI UniProt Show fit	ELK1, member of ETS oncogene family
chr9_-_66514567 Show fit	0.28	ENSMUST00000056890.8	Fbxl22 Links Ensembl NCBI MGI UniProt Show fit	F-box and leucine-rich repeat protein 22
chr19_+_4214238 Show fit	0.26	ENSMUST00000046506.6	Clcf1 Links Ensembl NCBI MGI UniProt Show fit	cardiotrophin-like cytokine factor 1
chr12_-_34528844 Show fit	0.26	ENSMUST00000110819.2	Hdac9 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 9
chr14_+_56017964 Show fit	0.24	ENSMUST00000022836.4	Mcpt1 Links Ensembl NCBI MGI UniProt Show fit	mast cell protease 1
chr10_-_14718191 Show fit	0.22	ENSMUST00000020016.4	Gje1 Links Ensembl NCBI MGI UniProt Show fit	gap junction protein, epsilon 1
chr15_+_62037986 Show fit	0.22	ENSMUST00000182956.1 ENSMUST00000182075.1 ENSMUST00000180432.2 ENSMUST00000181416.2 ENSMUST00000181657.2	Pvt1 Links Ensembl NCBI MGI UniProt Show fit	plasmacytoma variant translocation 1
chr2_+_86041317 Show fit	0.21	ENSMUST00000111589.1	Olfr1033 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1033
chr2_-_71367749 Show fit	0.20	ENSMUST00000151937.1	Slc25a12 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr3_-_88378699 Show fit	0.19	ENSMUST00000098956.2	Bglap2 Links Ensembl NCBI MGI UniProt Show fit	bone gamma-carboxyglutamate protein 2
chr1_-_174118014 Show fit	0.18	ENSMUST00000063030.3	Olfr231 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 231
chr16_+_91391721 Show fit	0.18	ENSMUST00000160764.1	Gm21970 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 21970
chr11_+_77686155 Show fit	0.18	ENSMUST00000100802.4 ENSMUST00000181023.1	Nufip2 Links Ensembl NCBI MGI UniProt Show fit	nuclear fragile X mental retardation protein interacting protein 2
chr17_-_44814649 Show fit	0.18	ENSMUST00000113571.3	Runx2 Links Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 2
chr16_+_25801907 Show fit	0.16	ENSMUST00000040231.6 ENSMUST00000115306.1 ENSMUST00000115304.1 ENSMUST00000115305.1	Trp63 Links Ensembl NCBI MGI UniProt Show fit	transformation related protein 63
chr11_+_75532127 Show fit	0.15	ENSMUST00000127226.1	Slc43a2 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 43, member 2
chr19_-_8839181 Show fit	0.15	ENSMUST00000096259.4	Gng3 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), gamma 3
chr17_-_44814604 Show fit	0.15	ENSMUST00000160673.1	Runx2 Links Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 2
chr16_-_38433145 Show fit	0.15	ENSMUST00000002926.6	Pla1a Links Ensembl NCBI MGI UniProt Show fit	phospholipase A1 member A
chr1_+_60746358 Show fit	0.14	ENSMUST00000027165.2	Cd28 Links Ensembl NCBI MGI UniProt Show fit	CD28 antigen
chr2_+_35691893 Show fit	0.13	ENSMUST00000065001.5	Dab2ip Links Ensembl NCBI MGI UniProt Show fit	disabled 2 interacting protein
chr15_+_62178175 Show fit	0.11	ENSMUST00000182476.1	Pvt1 Links Ensembl NCBI MGI UniProt Show fit	plasmacytoma variant translocation 1
chr1_+_36307745 Show fit	0.10	ENSMUST00000142319.1 ENSMUST00000097778.2 ENSMUST00000115031.1 ENSMUST00000115032.1 ENSMUST00000137906.1 ENSMUST00000115029.1	Arid5a Links Ensembl NCBI MGI UniProt Show fit	AT rich interactive domain 5A (MRF1-like)
chr6_-_83070225 Show fit	0.08	ENSMUST00000174674.1 ENSMUST00000089641.3	Tlx2 Links Ensembl NCBI MGI UniProt Show fit	T cell leukemia, homeobox 2
chr12_+_95692212 Show fit	0.08	ENSMUST00000057324.3	Flrt2 Links Ensembl NCBI MGI UniProt Show fit	fibronectin leucine rich transmembrane protein 2
chr3_-_107760221 Show fit	0.08	ENSMUST00000153114.1 ENSMUST00000118593.1 ENSMUST00000120243.1	Csf1 Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 1 (macrophage)
chr14_-_20618339 Show fit	0.08	ENSMUST00000035340.7	Usp54 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 54
chr7_-_132852657 Show fit	0.07	ENSMUST00000033257.8	Mettl10 Links Ensembl NCBI MGI UniProt Show fit	methyltransferase like 10
chr19_+_5050807 Show fit	0.06	ENSMUST00000025818.6	Rin1 Links Ensembl NCBI MGI UniProt Show fit	Ras and Rab interactor 1
chr4_+_102991784 Show fit	0.06	ENSMUST00000140654.1 ENSMUST00000169211.1	Tctex1d1 Links Ensembl NCBI MGI UniProt Show fit	Tctex1 domain containing 1
chr15_-_38519227 Show fit	0.05	ENSMUST00000110328.1 ENSMUST00000110329.1 ENSMUST00000065308.5	Azin1 Links Ensembl NCBI MGI UniProt Show fit	antizyme inhibitor 1
chrX_-_50942710 Show fit	0.05	ENSMUST00000060650.5	Frmd7 Links Ensembl NCBI MGI UniProt Show fit	FERM domain containing 7
chr4_+_65124174 Show fit	0.05	ENSMUST00000084501.3	Pappa Links Ensembl NCBI MGI UniProt Show fit	pregnancy-associated plasma protein A
chr18_+_37411674 Show fit	0.04	ENSMUST00000051126.2	Pcdhb10 Links Ensembl NCBI MGI UniProt Show fit	protocadherin beta 10
chr11_-_72215592 Show fit	0.04	ENSMUST00000021157.8	Med31 Links Ensembl NCBI MGI UniProt Show fit	mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr2_+_32629467 Show fit	0.04	ENSMUST00000068271.4	Ak1 Links Ensembl NCBI MGI UniProt Show fit	adenylate kinase 1
chr15_-_102722120 Show fit	0.03	ENSMUST00000171838.1	Calcoco1 Links Ensembl NCBI MGI UniProt Show fit	calcium binding and coiled coil domain 1
chr11_-_102218923 Show fit	0.02	ENSMUST00000131254.1	Hdac5 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 5
chr17_-_36958533 Show fit	0.02	ENSMUST00000172518.1	Znrd1 Links Ensembl NCBI MGI UniProt Show fit	zinc ribbon domain containing, 1
chr15_-_102722150 Show fit	0.02	ENSMUST00000023818.3	Calcoco1 Links Ensembl NCBI MGI UniProt Show fit	calcium binding and coiled coil domain 1
chr3_+_103058302 Show fit	0.01	ENSMUST00000029445.6	Nras Links Ensembl NCBI MGI UniProt Show fit	neuroblastoma ras oncogene
chr11_-_52282564 Show fit	0.00	ENSMUST00000086844.3	Tcf7 Links Ensembl NCBI MGI UniProt Show fit	transcription factor 7, T cell specific

View svg image
View png image

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.9	29.7	GO:0002149	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
4.4	13.2	GO:2000872	positive regulation of progesterone secretion(GO:2000872)
2.7	10.6	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
2.3	6.8	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
1.9	5.8	GO:0002865	regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
1.5	7.7	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
1.5	4.5	GO:0071663	granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
1.4	6.9	GO:0070103	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
1.1	4.6	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780)
0.7	4.3	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.7	6.4	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.7	8.5	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.7	2.0	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.6	6.0	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.6	4.6	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.6	2.9	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6	2.2	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.5	1.5	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.5	2.4	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.4	1.3	GO:0006597	spermine biosynthetic process(GO:0006597)
0.4	5.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4	1.1	GO:0021972	corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3	2.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.3	3.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.3	1.8	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.3	3.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.2	5.0	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.2	2.5	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.2	1.2	GO:0007386	compartment pattern specification(GO:0007386)
0.2	2.7	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.2	0.4	GO:2000554	regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.2	3.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2	0.4	GO:0072244	metanephric glomerular epithelium development(GO:0072244)
0.2	3.6	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.2	3.0	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.2	2.5	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.2	1.8	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.2	1.9	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2	0.5	GO:0002304	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2	0.7	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.2	0.8	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.2	0.2	GO:0060197	cloacal septation(GO:0060197)
0.2	2.1	GO:0043129	surfactant homeostasis(GO:0043129)
0.2	0.9	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1	3.9	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	2.7	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.1	0.7	GO:0050917	sensory perception of umami taste(GO:0050917)
0.1	3.7	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	2.8	GO:0048305	immunoglobulin secretion(GO:0048305)
0.1	2.8	GO:0010714	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1	1.0	GO:0035278	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1	0.4	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.4	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	2.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	2.6	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1	9.1	GO:0045667	regulation of osteoblast differentiation(GO:0045667)
0.1	5.4	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	1.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.9	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.0	0.8	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	2.1	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.1	GO:1903972	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0	0.8	GO:0035855	megakaryocyte development(GO:0035855)
0.0	1.5	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.1	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0	0.4	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	1.5	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.1	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.0	1.5	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	1.4	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0	3.3	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	2.3	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	1.7	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	29.7	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.5	6.0	GO:0070442	integrin alphaIIb-beta3 complex(GO:0070442)
0.9	2.8	GO:0038045	large latent transforming growth factor-beta complex(GO:0038045)
0.8	10.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.7	2.9	GO:0044194	cytolytic granule(GO:0044194)
0.5	5.6	GO:0097208	alveolar lamellar body(GO:0097208)
0.4	5.8	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3	4.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	3.6	GO:0000242	pericentriolar material(GO:0000242)
0.1	0.4	GO:0005608	laminin-3 complex(GO:0005608)
0.1	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	13.2	GO:0005604	basement membrane(GO:0005604)
0.1	2.1	GO:0031528	microvillus membrane(GO:0031528)
0.1	1.3	GO:0034362	low-density lipoprotein particle(GO:0034362) chylomicron(GO:0042627)
0.1	0.3	GO:0097059	CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1	1.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	0.8	GO:0031209	SCAR complex(GO:0031209)
0.1	6.9	GO:0016363	nuclear matrix(GO:0016363)
0.1	2.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	1.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	2.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	8.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.9	GO:0010369	chromocenter(GO:0010369)
0.0	3.2	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	5.7	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.0	1.0	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	4.3	GO:0005938	cell cortex(GO:0005938)
0.0	3.3	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.7	GO:0031519	PcG protein complex(GO:0031519)
0.0	4.6	GO:0005925	focal adhesion(GO:0005925)
0.0	1.2	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	2.5	GO:0030027	lamellipodium(GO:0030027)
0.0	5.1	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	3.2	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	4.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	3.0	GO:0005819	spindle(GO:0005819)
0.0	2.0	GO:0019898	extrinsic component of membrane(GO:0019898)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.2	10.6	GO:0033691	sialic acid binding(GO:0033691)
0.8	4.6	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.7	2.8	GO:0050436	microfibril binding(GO:0050436)
0.6	7.0	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.6	4.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6	2.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.5	7.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5	29.7	GO:0004601	peroxidase activity(GO:0004601)
0.4	1.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4	1.8	GO:0042610	CD8 receptor binding(GO:0042610)
0.3	2.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3	13.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.3	0.8	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	2.0	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2	1.3	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2	5.6	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.2	1.3	GO:0019808	polyamine binding(GO:0019808)
0.2	8.7	GO:0050699	WW domain binding(GO:0050699)
0.2	2.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2	3.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2	5.7	GO:0001968	fibronectin binding(GO:0001968)
0.1	3.2	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	1.1	GO:0043237	GTPase inhibitor activity(GO:0005095) laminin-1 binding(GO:0043237) Roundabout binding(GO:0048495)
0.1	0.4	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	3.2	GO:0043274	phospholipase binding(GO:0043274)
0.1	3.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	1.5	GO:0050692	DBD domain binding(GO:0050692)
0.1	3.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	2.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	0.3	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.1	0.7	GO:0008527	taste receptor activity(GO:0008527)
0.1	3.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	3.0	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	4.3	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.8	GO:0005123	death receptor binding(GO:0005123)
0.0	8.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	1.2	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.5	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	0.3	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	6.1	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.2	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	2.3	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	2.1	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	3.7	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	1.0	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.4	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	2.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.9	GO:0031491	nucleosome binding(GO:0031491)
0.0	1.3	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	34.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.5	5.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	16.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	14.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	6.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	6.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	2.7	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	2.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	2.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	7.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	5.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	3.2	PID ARF6 PATHWAY	Arf6 signaling events
0.1	4.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	3.8	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	2.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	6.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	4.0	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	4.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	5.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.2	5.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	2.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	2.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.7	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	3.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	3.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	3.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	3.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	2.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	2.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	8.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	2.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	1.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	3.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	2.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	4.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.8	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.1	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events