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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox21

Z-value: 1.09

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Transcription factors associated with Sox21

Gene Symbol Gene ID Gene Info
Sox21
ENSMUSG00000061517.7 SRY (sex determining region Y)-box 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox21mm10_v2_chr14_-_118237016_1182370350.353.4e-02Click!

Activity profile of Sox21 motif

Sorted Z-values of Sox21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_75270073 6.49 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr16_+_36277145 5.98 ENSMUST00000042097.9
Stfa1
stefin A1
chr2_-_28621932 4.58 ENSMUST00000028156.7
ENSMUST00000164290.1
Gfi1b
growth factor independent 1B
chr1_+_174172738 4.45 ENSMUST00000027817.7
Spta1
spectrin alpha, erythrocytic 1
chr7_-_142699510 4.28 ENSMUST00000105934.1
Ins2
insulin II
chr9_+_7558429 4.05 ENSMUST00000018765.2
Mmp8
matrix metallopeptidase 8
chr6_-_41035501 3.86 ENSMUST00000031931.5
2210010C04Rik
RIKEN cDNA 2210010C04 gene
chr6_-_78378851 3.24 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d
regenerating islet-derived 3 delta
chr2_+_174450678 3.14 ENSMUST00000016399.5
Tubb1
tubulin, beta 1 class VI
chr3_-_106024911 2.54 ENSMUST00000066537.3
ENSMUST00000054973.3
Chi3l7
chitinase 3-like 7
chr18_-_67549173 2.14 ENSMUST00000115050.1
Spire1
spire homolog 1 (Drosophila)
chr5_+_66676098 2.11 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr11_+_69045640 1.71 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb
aurora kinase B
chr4_-_87806276 1.70 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_+_42860776 1.67 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr1_+_107511416 1.56 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr10_-_97726755 1.51 ENSMUST00000166373.1
C030005K15Rik
RIKEN cDNA C030005K15 gene
chr8_-_25091341 1.36 ENSMUST00000125466.1
Plekha2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr7_+_30493622 1.34 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
Prodh2
proline dehydrogenase (oxidase) 2
chr10_-_62342674 1.30 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1
hexokinase 1
chr13_-_22219820 1.23 ENSMUST00000057516.1
Vmn1r193
vomeronasal 1 receptor 193
chr11_+_69964758 1.23 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
Cldn7
claudin 7
chr2_-_35979624 1.22 ENSMUST00000028248.4
ENSMUST00000112976.2
Ttll11
tubulin tyrosine ligase-like family, member 11
chr3_+_105870858 1.12 ENSMUST00000164730.1
Adora3
adenosine A3 receptor
chr8_-_111393810 1.10 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr2_-_140671462 1.08 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr19_-_39886730 1.08 ENSMUST00000168838.1
Cyp2c69
cytochrome P450, family 2, subfamily c, polypeptide 69
chr2_-_170194033 1.04 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr17_+_80307396 1.04 ENSMUST00000068175.5
Arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr13_-_19619820 1.03 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chrX_+_13632769 1.03 ENSMUST00000096492.3
Gpr34
G protein-coupled receptor 34
chr8_+_93810832 1.01 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1
guanine nucleotide binding protein, alpha O
chr2_+_153943919 1.00 ENSMUST00000099181.1
Bpifb4
BPI fold containing family B, member 4
chr1_-_172027251 0.99 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr13_-_32851176 0.92 ENSMUST00000091668.5
ENSMUST00000076352.6
Serpinb1a
serine (or cysteine) peptidase inhibitor, clade B, member 1a
chr7_-_25675047 0.91 ENSMUST00000108404.1
ENSMUST00000108405.1
ENSMUST00000079439.3
Tmem91
transmembrane protein 91
chr3_-_59220150 0.90 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_-_73452666 0.88 ENSMUST00000151939.1
Wipf1
WAS/WASL interacting protein family, member 1
chr17_+_17887840 0.84 ENSMUST00000054871.5
ENSMUST00000064068.4
Fpr3
Fpr2
formyl peptide receptor 3
formyl peptide receptor 2
chr6_-_145434925 0.81 ENSMUST00000111708.2
Ifltd1
intermediate filament tail domain containing 1
chr3_+_105870898 0.78 ENSMUST00000010279.5
Adora3
adenosine A3 receptor
chr8_-_24824049 0.78 ENSMUST00000050300.7
Adam5
a disintegrin and metallopeptidase domain 5
chr13_-_44455303 0.77 ENSMUST00000183264.1
Gm27007
predicted gene, 27007
chr11_+_32000452 0.71 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2
neuron specific gene family member 2
chrX_+_111168340 0.71 ENSMUST00000075226.4
Gm10112
predicted pseudogene 10112
chr8_+_105827721 0.71 ENSMUST00000034365.4
Tsnaxip1
translin-associated factor X (Tsnax) interacting protein 1
chr6_-_130233322 0.69 ENSMUST00000032286.6
Klra7
killer cell lectin-like receptor, subfamily A, member 7
chr3_-_10208569 0.67 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr11_-_109472611 0.67 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr10_+_42860648 0.67 ENSMUST00000105495.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr17_-_6655939 0.65 ENSMUST00000179554.1
Dynlt1f
dynein light chain Tctex-type 1F
chr17_-_6317474 0.64 ENSMUST00000169415.1
Dynlt1a
dynein light chain Tctex-type 1A
chr2_-_72986716 0.64 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr6_+_52177498 0.63 ENSMUST00000070587.3
5730596B20Rik
RIKEN cDNA 5730596B20 gene
chr13_-_100317674 0.62 ENSMUST00000118574.1
Naip6
NLR family, apoptosis inhibitory protein 6
chr1_-_172027269 0.62 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr6_-_16898441 0.62 ENSMUST00000031533.7
Tfec
transcription factor EC
chr1_-_97661950 0.60 ENSMUST00000053033.7
ENSMUST00000149927.1
D1Ertd622e
DNA segment, Chr 1, ERATO Doi 622, expressed
chrX_+_106583184 0.59 ENSMUST00000101296.2
ENSMUST00000101297.3
Gm5127
predicted gene 5127
chr1_-_30999905 0.58 ENSMUST00000152491.1
Gm5699
predicted gene 5699
chr4_-_49593875 0.57 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr11_+_89073841 0.55 ENSMUST00000100619.4
Gm525
predicted gene 525
chr7_-_19421326 0.55 ENSMUST00000047020.1
A930016O22Rik
RIKEN cDNA A930016O22 gene
chr19_-_8798495 0.50 ENSMUST00000096261.3
Polr2g
polymerase (RNA) II (DNA directed) polypeptide G
chr6_-_129660556 0.49 ENSMUST00000119533.1
ENSMUST00000145984.1
ENSMUST00000118401.1
ENSMUST00000071920.4
Klrc2
killer cell lectin-like receptor subfamily C, member 2
chr16_+_16870829 0.49 ENSMUST00000131063.1
Top3b
topoisomerase (DNA) III beta
chr2_-_147186389 0.48 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2
NK2 homeobox 2
chr17_+_47737030 0.48 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr17_-_26099257 0.48 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr17_+_6430112 0.48 ENSMUST00000179569.1
Dynlt1b
dynein light chain Tctex-type 1B
chr2_-_45110336 0.46 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_119271202 0.45 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr2_-_170131156 0.43 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr4_-_131967824 0.42 ENSMUST00000146443.1
ENSMUST00000135579.1
Epb4.1
erythrocyte protein band 4.1
chr15_-_60824942 0.42 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr14_+_53757356 0.41 ENSMUST00000180380.1
Trav13-4-dv7
T cell receptor alpha variable 13-4-DV7
chr19_+_11518493 0.40 ENSMUST00000025580.3
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr10_-_62507737 0.38 ENSMUST00000020271.6
Srgn
serglycin
chr16_-_90810365 0.37 ENSMUST00000140920.1
Urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr18_-_34007206 0.37 ENSMUST00000025234.5
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr1_-_125913101 0.36 ENSMUST00000161361.1
Lypd1
Ly6/Plaur domain containing 1
chr5_+_19907502 0.36 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_116708467 0.36 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr6_+_84008540 0.36 ENSMUST00000113821.1
ENSMUST00000113823.1
Dysf
dysferlin
chr17_-_70998010 0.36 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_+_6601671 0.35 ENSMUST00000092966.4
Dynlt1c
dynein light chain Tctex-type 1C
chr2_-_155582656 0.35 ENSMUST00000126322.1
Gss
glutathione synthetase
chrX_+_166170449 0.34 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
Gemin8
gem (nuclear organelle) associated protein 8
chr19_-_24961545 0.32 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr12_+_38783503 0.32 ENSMUST00000159334.1
Etv1
ets variant gene 1
chrX_-_75578188 0.32 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr11_-_94782703 0.31 ENSMUST00000100554.1
Tmem92
transmembrane protein 92
chr12_-_40134175 0.31 ENSMUST00000078481.7
ENSMUST00000002640.5
Scin
scinderin
chr8_-_57652993 0.29 ENSMUST00000110316.2
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr3_-_130709419 0.29 ENSMUST00000043937.7
Ostc
oligosaccharyltransferase complex subunit
chr10_+_56377300 0.28 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr19_+_7557452 0.28 ENSMUST00000025925.4
ENSMUST00000136465.1
Pla2g16
phospholipase A2, group XVI
chr19_+_7557473 0.28 ENSMUST00000141887.1
ENSMUST00000136756.1
Pla2g16
phospholipase A2, group XVI
chr1_-_135585314 0.28 ENSMUST00000040599.8
ENSMUST00000067414.6
Nav1
neuron navigator 1
chr18_+_37504264 0.28 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr10_-_28986280 0.27 ENSMUST00000152363.1
ENSMUST00000015663.6
2310057J18Rik
RIKEN cDNA 2310057J18 gene
chr7_-_102857271 0.26 ENSMUST00000071393.2
Olfr566
olfactory receptor 566
chr2_+_167015193 0.26 ENSMUST00000018143.9
ENSMUST00000176066.1
ENSMUST00000150571.1
Ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr15_-_57265126 0.26 ENSMUST00000137764.1
ENSMUST00000022995.6
Slc22a22
solute carrier family 22 (organic cation transporter), member 22
chr1_+_74362108 0.25 ENSMUST00000097697.1
Gm216
predicted gene 216
chr10_-_10472314 0.24 ENSMUST00000179956.1
ENSMUST00000172530.1
ENSMUST00000132573.1
Adgb
androglobin
chr17_+_35108279 0.24 ENSMUST00000037849.2
Ly6g5c
lymphocyte antigen 6 complex, locus G5C
chrM_+_11734 0.23 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr1_+_72284367 0.22 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169
transmembrane protein 169
chr14_+_118267158 0.21 ENSMUST00000171107.1
Gm9376
predicted gene 9376
chr2_-_79908389 0.21 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr10_-_130127055 0.19 ENSMUST00000074161.1
Olfr824
olfactory receptor 824
chr10_-_117238665 0.19 ENSMUST00000020392.4
9530003J23Rik
RIKEN cDNA 9530003J23 gene
chr10_-_13388753 0.19 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr11_+_32000496 0.19 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr2_+_65620829 0.18 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr6_+_65590382 0.17 ENSMUST00000114236.1
Tnip3
TNFAIP3 interacting protein 3
chr7_+_24112314 0.17 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112
zinc finger protein 112
chr10_-_39122277 0.16 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr10_-_116972609 0.16 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr8_-_62123106 0.15 ENSMUST00000034052.6
ENSMUST00000034054.7
Anxa10
annexin A10
chr2_-_79908428 0.15 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr1_-_135167606 0.15 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr12_-_102423741 0.14 ENSMUST00000110020.1
Lgmn
legumain
chr9_-_69451035 0.14 ENSMUST00000071565.5
Gm4978
predicted gene 4978
chr8_-_34965631 0.14 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr7_+_80862108 0.13 ENSMUST00000044115.7
Zscan2
zinc finger and SCAN domain containing 2
chr6_+_57002300 0.13 ENSMUST00000079669.4
Vmn1r6
vomeronasal 1 receptor 6
chr7_+_27862557 0.13 ENSMUST00000053722.8
Zfp607
zinc finger proten 607
chr4_+_138775735 0.12 ENSMUST00000030528.2
Pla2g2d
phospholipase A2, group IID
chr8_-_107439585 0.12 ENSMUST00000077208.4
Rps26-ps1
ribosomal protein S26, pseudogene 1
chr4_+_129906205 0.12 ENSMUST00000145196.1
ENSMUST00000141731.1
ENSMUST00000129149.1
E330017L17Rik
RIKEN cDNA E330017L17 gene
chr16_+_16870736 0.11 ENSMUST00000139740.1
ENSMUST00000119787.2
ENSMUST00000130650.1
ENSMUST00000156502.1
ENSMUST00000023465.7
ENSMUST00000124960.1
ENSMUST00000144513.1
Top3b
topoisomerase (DNA) III beta
chr7_+_28277706 0.11 ENSMUST00000094651.2
Eid2b
EP300 interacting inhibitor of differentiation 2B
chr17_+_35916541 0.10 ENSMUST00000087211.2
Ppp1r10
protein phosphatase 1, regulatory subunit 10
chr6_-_106745109 0.10 ENSMUST00000167925.2
Il5ra
interleukin 5 receptor, alpha
chr1_-_75223654 0.08 ENSMUST00000179573.1
A630095N17Rik
RIKEN cDNA A630095N17 gene
chr3_+_92365178 0.08 ENSMUST00000050397.1
Sprr2f
small proline-rich protein 2F
chr3_-_19264959 0.08 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr1_-_166238725 0.08 ENSMUST00000038782.3
Mael
maelstrom homolog (Drosophila)
chr4_+_146654927 0.08 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr4_-_63622421 0.08 ENSMUST00000102862.3
1700018C11Rik
RIKEN cDNA 1700018C11 gene
chr5_-_113724749 0.07 ENSMUST00000047891.5
ENSMUST00000162388.1
1700069L16Rik
RIKEN cDNA 1700069L16 gene
chr6_+_56956466 0.07 ENSMUST00000096612.3
Vmn1r4
vomeronasal 1 receptor 4
chr3_-_117077760 0.07 ENSMUST00000029642.5
1700061I17Rik
RIKEN cDNA 1700061I17 gene
chr11_+_87699897 0.06 ENSMUST00000040089.4
Rnf43
ring finger protein 43
chr14_+_26693267 0.06 ENSMUST00000022433.4
Dnah12
dynein, axonemal, heavy chain 12
chr6_-_56797637 0.05 ENSMUST00000114323.1
Kbtbd2
kelch repeat and BTB (POZ) domain containing 2
chr12_-_81568474 0.05 ENSMUST00000008582.3
Adam21
a disintegrin and metallopeptidase domain 21
chr9_+_119894876 0.04 ENSMUST00000036561.6
Wdr48
WD repeat domain 48
chr4_+_85205120 0.03 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr15_+_6708372 0.03 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr11_-_53707269 0.02 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50
RAD50 homolog (S. cerevisiae)
chr10_-_52194956 0.02 ENSMUST00000117992.2
Ros1
Ros1 proto-oncogene
chr7_+_123123870 0.02 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr10_-_24092320 0.01 ENSMUST00000092654.2
Taar8b
trace amine-associated receptor 8B
chr17_+_35916977 0.01 ENSMUST00000151664.1
Ppp1r10
protein phosphatase 1, regulatory subunit 10
chr15_-_101438788 0.00 ENSMUST00000081945.3
Krt83
keratin 83

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:1990535 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.7 2.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.6 4.6 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.6 1.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.5 1.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.4 1.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 2.1 GO:0007412 axon target recognition(GO:0007412)
0.3 1.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 0.9 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 1.9 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 1.3 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.5 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.2 GO:0051013 microtubule severing(GO:0051013)
0.2 4.1 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.3 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.1 0.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.5 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 1.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 4.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.4 GO:0033373 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.1 0.5 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:0006265 DNA topological change(GO:0006265)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.6 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 15.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.6 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 1.4 GO:0019236 response to pheromone(GO:0019236)
0.0 1.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 3.1 GO:0051225 spindle assembly(GO:0051225)
0.0 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.4 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.0 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.5 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.5 GO:0032437 cuticular plate(GO:0032437)
0.4 1.6 GO:0060187 cell pole(GO:0060187)
0.3 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 4.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 2.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 4.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0071547 piP-body(GO:0071547)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.3 2.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.6 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.3 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.8 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 4.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 15.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0043236 fibronectin binding(GO:0001968) laminin binding(GO:0043236)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.3 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0 1.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 3.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 4.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 7.4 GO:0003779 actin binding(GO:0003779)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.1 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 12.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 4.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells