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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tead3_Tead4

Z-value: 1.68

Motif logo

Transcription factors associated with Tead3_Tead4

Gene Symbol Gene ID Gene Info
ENSMUSG00000002249.11 TEA domain family member 3
ENSMUSG00000030353.9 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tead4mm10_v2_chr6_-_128300738_1283008230.791.1e-08Click!
Tead3mm10_v2_chr17_-_28350747_283508200.521.0e-03Click!

Activity profile of Tead3_Tead4 motif

Sorted Z-values of Tead3_Tead4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_43558386 15.14 ENSMUST00000130353.1
talin 1
chr16_+_38362205 12.58 ENSMUST00000023494.6
popeye domain containing 2
chr16_+_38362234 9.95 ENSMUST00000114739.1
popeye domain containing 2
chr8_-_85365317 9.15 ENSMUST00000034133.7
myosin light chain kinase 3
chr8_-_85365341 8.96 ENSMUST00000121972.1
myosin light chain kinase 3
chr17_-_35702297 8.02 ENSMUST00000135078.1
discoidin domain receptor family, member 1
chr3_-_90695706 7.63 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr7_-_24760311 7.34 ENSMUST00000063956.5
CD177 antigen
chr19_-_34255325 7.27 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr6_-_67535783 7.22 ENSMUST00000058178.4
tumor-associated calcium signal transducer 2
chr7_-_132813799 7.10 ENSMUST00000097998.2
family with sequence similarity 53, member B
chr1_+_43730593 6.82 ENSMUST00000027217.8
RIKEN cDNA 1500015O10 gene
chr8_-_123894736 6.63 ENSMUST00000034453.4
actin, alpha 1, skeletal muscle
chrX_+_136224035 6.61 ENSMUST00000113116.2
transcription elongation factor A (SII)-like 7
chr7_-_34133215 6.34 ENSMUST00000038537.8
WT1-interacting protein
chr12_-_76709997 5.73 ENSMUST00000166101.1
spectrin beta, erythrocytic
chr11_-_116077927 5.64 ENSMUST00000156545.1
unc-13 homolog D (C. elegans)
chr5_+_76840597 5.46 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
RIKEN cDNA C530008M17 gene
chr17_+_71019548 5.44 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr18_+_50030977 5.22 ENSMUST00000145726.1
ENSMUST00000128377.1
tumor necrosis factor, alpha-induced protein 8
chr4_-_118457450 5.20 ENSMUST00000106375.1
ENSMUST00000006556.3
ENSMUST00000168404.1
myeloproliferative leukemia virus oncogene
chr6_-_115758974 5.12 ENSMUST00000072933.6
transmembrane protein 40
chr17_+_71019503 5.11 ENSMUST00000024847.7
myomesin 1
chr19_+_38132767 5.10 ENSMUST00000025956.5
ENSMUST00000112329.1
phosphodiesterase 6C, cGMP specific, cone, alpha prime
chr18_+_61953048 4.97 ENSMUST00000051720.5
SH3 domain and tetratricopeptide repeats 2
chr4_-_118457509 4.87 ENSMUST00000102671.3
myeloproliferative leukemia virus oncogene
chr11_-_116077954 4.72 ENSMUST00000106451.1
ENSMUST00000075036.2
unc-13 homolog D (C. elegans)
chr14_-_54994541 4.66 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
myosin, heavy polypeptide 7, cardiac muscle, beta
chr11_-_116077562 4.65 ENSMUST00000174822.1
unc-13 homolog D (C. elegans)
chr4_-_88033328 4.62 ENSMUST00000078090.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_44524642 4.53 ENSMUST00000165208.2
myosin binding protein C, fast-type
chr17_-_35701937 4.52 ENSMUST00000155628.1
discoidin domain receptor family, member 1
chr11_+_104577281 4.39 ENSMUST00000106956.3
myosin, light polypeptide 4
chr7_-_132813715 4.38 ENSMUST00000134946.1
family with sequence similarity 53, member B
chr17_-_35702040 4.11 ENSMUST00000166980.2
ENSMUST00000145900.1
discoidin domain receptor family, member 1
chrX_-_142306170 4.10 ENSMUST00000134825.2
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr14_-_54966570 3.94 ENSMUST00000124930.1
ENSMUST00000134256.1
ENSMUST00000081857.6
ENSMUST00000145322.1
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr18_+_60911757 3.87 ENSMUST00000040359.5
arylsulfatase i
chr18_+_23415400 3.83 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr1_+_135836380 3.74 ENSMUST00000178204.1
troponin T2, cardiac
chr11_+_62077018 3.73 ENSMUST00000092415.5
sperm antigen with calponin homology and coiled-coil domains 1
chr2_+_91035613 3.73 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
receptor-associated protein of the synapse
chr11_+_104576965 3.69 ENSMUST00000106957.1
myosin, light polypeptide 4
chr1_+_189728264 3.62 ENSMUST00000097442.2
protein tyrosine phosphatase, non-receptor type 14
chr11_+_44519405 3.58 ENSMUST00000101327.2
ring finger protein 145
chr8_-_122551316 3.55 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr12_+_85746539 3.44 ENSMUST00000040461.3
major facilitator superfamily domain containing 7C
chr9_-_18512885 3.42 ENSMUST00000034653.6
mucin 16
chr7_-_38107490 3.40 ENSMUST00000108023.3
cyclin E1
chr15_-_58324161 3.37 ENSMUST00000022985.1
kelch-like 38
chr4_+_49059256 3.36 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr3_+_153844209 3.31 ENSMUST00000044089.3
ankyrin repeat and SOCS box-containing 17
chr18_-_60501983 3.31 ENSMUST00000042710.6
small integral membrane protein 3
chr18_+_50053282 3.27 ENSMUST00000148159.2
tumor necrosis factor, alpha-induced protein 8
chr4_-_134018829 3.26 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr4_-_4138432 3.15 ENSMUST00000070375.7
preproenkephalin
chr7_+_26061495 3.05 ENSMUST00000005669.7
cytochrome P450, family 2, subfamily b, polypeptide 13
chrX_-_49788204 3.05 ENSMUST00000114893.1
immunoglobulin superfamily, member 1
chr9_+_69454066 2.99 ENSMUST00000134907.1
annexin A2
chr17_+_47593516 2.96 ENSMUST00000182874.1
cyclin D3
chr11_+_98412461 2.92 ENSMUST00000058295.5
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr2_-_156839790 2.92 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
predicted gene 14230
chr4_+_154237525 2.91 ENSMUST00000152159.1
multiple EGF-like-domains 6
chr14_-_69284982 2.84 ENSMUST00000183882.1
ENSMUST00000037064.4
solute carrier family 25, member 37
chr8_-_104624266 2.80 ENSMUST00000163783.2
cadherin 16
chr13_-_117025505 2.80 ENSMUST00000022239.6
poly (ADP-ribose) polymerase family, member 8
chr6_-_136835426 2.80 ENSMUST00000068293.3
ENSMUST00000111894.1
single-pass membrane protein with coiled-coil domains 3
chr15_+_6386598 2.80 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
disabled 2, mitogen-responsive phosphoprotein
chr1_-_66945019 2.77 ENSMUST00000027151.5
myosin, light polypeptide 1
chr8_+_57511833 2.75 ENSMUST00000067925.6
high mobility group box 2
chr4_+_134315112 2.74 ENSMUST00000105875.1
ENSMUST00000030638.6
tripartite motif-containing 63
chr11_-_100970887 2.73 ENSMUST00000060792.5
polymerase I and transcript release factor
chr14_-_69503220 2.65 ENSMUST00000180059.2
predicted gene, 21464
chr1_-_66945361 2.61 ENSMUST00000160100.1
myosin, light polypeptide 1
chr14_-_69503316 2.49 ENSMUST00000179116.2
predicted gene, 21464
chr2_-_92370999 2.46 ENSMUST00000176810.1
ENSMUST00000090582.4
glycosyltransferase-like 1B
chr6_-_128300738 2.44 ENSMUST00000143004.1
ENSMUST00000006311.6
ENSMUST00000112157.2
ENSMUST00000133118.1
TEA domain family member 4
chr9_-_95815389 2.44 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr6_+_29433248 2.42 ENSMUST00000101617.2
ENSMUST00000065090.5
filamin C, gamma
chr17_+_47593444 2.40 ENSMUST00000182209.1
cyclin D3
chr16_-_42340595 2.40 ENSMUST00000102817.4
growth associated protein 43
chr2_-_92371039 2.39 ENSMUST00000068586.6
glycosyltransferase-like 1B
chr5_+_150259922 2.38 ENSMUST00000087204.5
furry homolog (Drosophila)
chr5_+_31116722 2.35 ENSMUST00000114637.1
tripartite motif-containing 54
chr5_+_31116702 2.35 ENSMUST00000013771.8
tripartite motif-containing 54
chr4_-_126163470 2.34 ENSMUST00000097891.3
SH3 domain containing 21
chr9_-_96437434 2.18 ENSMUST00000070500.2
cDNA sequence BC043934
chr4_+_120588728 2.18 ENSMUST00000171482.1
predicted gene 8439
chr7_+_127211608 2.16 ENSMUST00000032910.6
myosin light chain, phosphorylatable, fast skeletal muscle
chr15_+_54410755 2.10 ENSMUST00000036737.3
collectin sub-family member 10
chr17_-_71002488 2.10 ENSMUST00000148960.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr10_-_42276688 2.05 ENSMUST00000175881.1
ENSMUST00000056974.3
forkhead box O3
chr16_+_26463135 2.04 ENSMUST00000161053.1
ENSMUST00000115302.1
claudin 16
chrX_+_56454871 2.03 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr2_-_92370968 2.03 ENSMUST00000176774.1
glycosyltransferase-like 1B
chrX_+_139217166 2.02 ENSMUST00000166444.1
ENSMUST00000170671.1
ENSMUST00000113041.2
ENSMUST00000113042.2
melanoma associated antigen (mutated) 1-like 1
chr10_-_62814539 2.02 ENSMUST00000173087.1
ENSMUST00000174121.1
tet methylcytosine dioxygenase 1
chr4_+_135120640 2.02 ENSMUST00000056977.7
runt related transcription factor 3
chrX_-_74246364 1.97 ENSMUST00000130007.1
filamin, alpha
chr17_+_8236031 1.95 ENSMUST00000164411.2
chemokine (C-C motif) receptor 6
chr6_+_29433131 1.94 ENSMUST00000090474.4
filamin C, gamma
chr16_+_30008657 1.93 ENSMUST00000181485.1
RIKEN cDNA 4632428C04 gene
chr16_+_87553313 1.93 ENSMUST00000026700.7
Map3k7 C-terminal like
chr11_-_5803733 1.88 ENSMUST00000020768.3
phosphoglycerate mutase 2
chr8_-_48555846 1.85 ENSMUST00000110345.1
ENSMUST00000110343.1
teneurin transmembrane protein 3
chrX_-_74246534 1.83 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr3_+_19644452 1.82 ENSMUST00000029139.7
tripartite motif-containing 55
chr6_+_29694204 1.80 ENSMUST00000046750.7
ENSMUST00000115250.3
tetraspanin 33
chr7_+_29303938 1.77 ENSMUST00000108231.1
D4, zinc and double PHD fingers family 1
chr6_+_87428986 1.74 ENSMUST00000032125.5
bone morphogenetic protein 10
chr1_-_149922339 1.74 ENSMUST00000111926.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr2_-_58160495 1.73 ENSMUST00000028175.6
cytohesin 1 interacting protein
chr3_-_116807733 1.70 ENSMUST00000159670.1
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr7_-_132317198 1.69 ENSMUST00000080215.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr1_-_126830632 1.68 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr13_+_55369732 1.66 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr2_-_73486456 1.66 ENSMUST00000141264.1
WAS/WASL interacting protein family, member 1
chr1_+_51289106 1.63 ENSMUST00000051572.6
serum deprivation response
chr14_+_70890099 1.60 ENSMUST00000022699.8
glial cell line derived neurotrophic factor family receptor alpha 2
chr5_-_69542622 1.58 ENSMUST00000031045.6
Yip1 domain family, member 7
chr8_-_12573311 1.57 ENSMUST00000180858.1
RIKEN cDNA D630011A20 gene
chr6_+_122513676 1.57 ENSMUST00000142896.1
ENSMUST00000121656.1
microfibrillar associated protein 5
chr7_-_28372597 1.55 ENSMUST00000144700.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr4_-_11965699 1.55 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chrX_+_96456362 1.54 ENSMUST00000079322.5
ENSMUST00000113838.1
hephaestin
chr19_+_33822908 1.54 ENSMUST00000042061.6
predicted pseudogene 5519
chr11_+_100415697 1.52 ENSMUST00000001595.3
FK506 binding protein 10
chr9_+_69453620 1.51 ENSMUST00000034756.8
ENSMUST00000123470.1
annexin A2
chr13_+_109926832 1.50 ENSMUST00000117420.1
phosphodiesterase 4D, cAMP specific
chr4_-_132398199 1.49 ENSMUST00000136711.1
ENSMUST00000084249.4
phosphatase and actin regulator 4
chr11_+_100415722 1.48 ENSMUST00000107400.2
FK506 binding protein 10
chr13_-_113046357 1.47 ENSMUST00000022282.3
glutathione peroxidase 8 (putative)
chr5_+_66968559 1.45 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr6_+_122513643 1.42 ENSMUST00000118626.1
microfibrillar associated protein 5
chr17_-_34615965 1.42 ENSMUST00000097345.3
ENSMUST00000015611.7
EGF-like domain 8
chr15_-_79254737 1.40 ENSMUST00000039752.3
solute carrier family 16 (monocarboxylic acid transporters), member 8
chr2_+_156840077 1.39 ENSMUST00000081335.6
ENSMUST00000073352.3
TGFB-induced factor homeobox 2
chr8_+_121950492 1.38 ENSMUST00000093078.6
ENSMUST00000170857.1
ENSMUST00000026354.8
ENSMUST00000174753.1
ENSMUST00000172511.1
BTG3 associated nuclear protein
chr2_-_73485733 1.38 ENSMUST00000102680.1
WAS/WASL interacting protein family, member 1
chr6_-_28831747 1.37 ENSMUST00000062304.5
leucine rich repeat containing 4
chr13_-_62858364 1.37 ENSMUST00000021907.7
fructose bisphosphatase 2
chrX_-_12128386 1.37 ENSMUST00000145872.1
BCL6 interacting corepressor
chr19_-_32210969 1.36 ENSMUST00000151289.1
sphingomyelin synthase 1
chr2_-_148443543 1.36 ENSMUST00000099269.3
CD93 antigen
chr16_+_11984581 1.35 ENSMUST00000170672.2
ENSMUST00000023138.7
shisa homolog 9 (Xenopus laevis)
chr15_-_42676967 1.34 ENSMUST00000022921.5
angiopoietin 1
chr3_+_88364548 1.34 ENSMUST00000147948.1
ENSMUST00000147991.1
progestin and adipoQ receptor family member VI
chr1_+_156558759 1.33 ENSMUST00000173929.1
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr2_-_120404058 1.32 ENSMUST00000090042.5
ENSMUST00000110729.1
ENSMUST00000090046.5
transmembrane protein 87A
chr1_+_171155512 1.31 ENSMUST00000111334.1
myelin protein zero
chr17_+_34608997 1.29 ENSMUST00000114140.3
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr4_+_133176336 1.28 ENSMUST00000105912.1
WAS protein family, member 2
chr1_-_136234113 1.27 ENSMUST00000120339.1
ENSMUST00000048668.8
RIKEN cDNA 5730559C18 gene
chr18_+_82554463 1.26 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
myelin basic protein
chr2_+_121295437 1.26 ENSMUST00000110639.1
microtubule-associated protein 1 A
chr6_+_41684414 1.25 ENSMUST00000031900.5
RIKEN cDNA 1700034O15 gene
chr11_-_60913775 1.25 ENSMUST00000019075.3
predicted gene, Gm16515
chr3_-_144819494 1.23 ENSMUST00000029929.7
chloride channel calcium activated 2
chr9_-_48340876 1.23 ENSMUST00000034527.7
neurexophilin and PC-esterase domain family, member 2
chrX_-_51681856 1.23 ENSMUST00000114871.1
heparan sulfate 6-O-sulfotransferase 2
chr11_+_101984270 1.22 ENSMUST00000176722.1
ENSMUST00000175972.1
RIKEN cDNA 1700006E09 gene
chr1_-_153186447 1.21 ENSMUST00000027753.6
laminin, gamma 2
chr6_+_17307040 1.21 ENSMUST00000123439.1
caveolin 1, caveolae protein
chr7_-_28372494 1.21 ENSMUST00000119990.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr8_+_110266960 1.20 ENSMUST00000043141.6
HYDIN, axonemal central pair apparatus protein
chr17_-_47834682 1.20 ENSMUST00000066368.6
MyoD family inhibitor
chrX_-_51681703 1.20 ENSMUST00000088172.5
heparan sulfate 6-O-sulfotransferase 2
chr11_+_87109221 1.19 ENSMUST00000020794.5
spindle and kinetochore associated complex subunit 2
chr3_+_88532314 1.17 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr12_-_55014329 1.17 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr17_-_35697971 1.17 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr1_+_12692430 1.16 ENSMUST00000180062.1
ENSMUST00000177608.1
sulfatase 1
chr11_-_67771115 1.16 ENSMUST00000051765.8
glucagon-like peptide 2 receptor
chr18_-_47333311 1.15 ENSMUST00000126684.1
ENSMUST00000156422.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_+_24595623 1.14 ENSMUST00000176228.1
ENSMUST00000129142.1
connective tissue growth factor
chr17_-_71002017 1.13 ENSMUST00000128179.1
ENSMUST00000150456.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr16_-_36784924 1.13 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
solute carrier family 15 (H+/peptide transporter), member 2
chrX_+_72987339 1.12 ENSMUST00000164800.1
ENSMUST00000114546.2
zinc finger protein 185
chr11_+_96323253 1.12 ENSMUST00000093944.3
homeobox B3
chr15_-_36598019 1.12 ENSMUST00000155116.1
poly(A) binding protein, cytoplasmic 1
chr8_-_87804411 1.10 ENSMUST00000165770.2
zinc finger protein 423
chr6_+_122513583 1.09 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr9_+_75071579 1.09 ENSMUST00000136731.1
myosin VA
chrX_+_6415736 1.08 ENSMUST00000143641.3
shroom family member 4
chr16_-_95586585 1.08 ENSMUST00000077773.6
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr3_+_37639985 1.08 ENSMUST00000108107.1
sprouty homolog 1 (Drosophila)
chr2_+_30595037 1.07 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr11_+_69125896 1.07 ENSMUST00000021268.2
arachidonate lipoxygenase 3
chr7_-_14562171 1.06 ENSMUST00000181796.1
vomeronasal 1 receptor 90
chr15_+_98632220 1.06 ENSMUST00000109150.1
calcium channel, voltage-dependent, beta 3 subunit
chr16_-_38800193 1.05 ENSMUST00000057767.4
uroplakin 1B
chr11_+_115974709 1.05 ENSMUST00000021107.7
ENSMUST00000106461.1
ENSMUST00000169928.1
integrin beta 4
chr4_-_83052229 1.05 ENSMUST00000107230.1
Fras1 related extracellular matrix protein 1
chr13_-_77131276 1.05 ENSMUST00000159300.1
ankyrin repeat domain 32
chr4_-_154636831 1.04 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
PR domain containing 16
chr16_+_77014069 1.02 ENSMUST00000023580.6
ubiquitin specific peptidase 25
chr6_-_142507805 1.02 ENSMUST00000134191.1
ENSMUST00000032373.5
lactate dehydrogenase B
chr4_-_83052147 1.02 ENSMUST00000170248.2
Fras1 related extracellular matrix protein 1
chr19_-_57197496 1.02 ENSMUST00000111544.1
actin-binding LIM protein 1
chr10_-_13324250 1.01 ENSMUST00000105543.1
phosphatase and actin regulator 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead3_Tead4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 22.5 GO:0060931 sinoatrial node cell development(GO:0060931)
3.4 10.1 GO:0035702 monocyte homeostasis(GO:0035702)
3.0 18.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
2.5 7.6 GO:0070488 neutrophil aggregation(GO:0070488)
1.9 15.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
1.7 15.0 GO:0002432 granuloma formation(GO:0002432)
1.5 17.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.3 3.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.2 3.7 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.1 5.6 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.1 6.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.0 15.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.9 4.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.9 2.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.9 3.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.8 7.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.8 3.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.8 6.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.7 4.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.7 2.9 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.7 4.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.6 2.4 GO:1902896 terminal web assembly(GO:1902896)
0.6 9.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 1.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.5 3.2 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.5 2.0 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.5 2.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.4 1.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.4 3.4 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.4 5.1 GO:0046549 retinal cone cell development(GO:0046549)
0.4 1.3 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.4 2.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 1.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.4 2.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.4 3.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.4 1.9 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 1.5 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 1.9 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 3.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 2.5 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.3 1.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 2.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.3 2.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 1.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.3 1.6 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 2.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.3 5.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.7 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 1.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 2.4 GO:0016198 axon choice point recognition(GO:0016198)
0.2 0.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.9 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.2 1.1 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 4.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 1.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 1.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.4 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 1.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.8 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.2 1.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 0.7 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228) pancreas morphogenesis(GO:0061113)
0.2 2.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.5 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.8 GO:0097264 self proteolysis(GO:0097264)
0.2 0.5 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.2 0.7 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 1.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 7.8 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 0.8 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.2 1.7 GO:0035878 nail development(GO:0035878)
0.2 1.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 0.5 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.2 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 5.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 4.1 GO:0097435 fibril organization(GO:0097435)
0.1 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 8.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 5.7 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.5 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 9.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 1.0 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 1.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 2.0 GO:0070633 transepithelial transport(GO:0070633)
0.1 0.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 2.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 1.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.8 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.3 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 3.4 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.8 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 2.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.4 GO:0035522 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 1.0 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 1.9 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 3.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.8 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 3.2 GO:0006826 iron ion transport(GO:0006826)
0.1 1.0 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 0.7 GO:0015879 carnitine transport(GO:0015879)
0.1 2.0 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 4.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 1.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 1.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 3.2 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418) chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.9 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.7 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 3.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.7 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.0 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.7 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 2.1 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.4 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.5 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 1.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.4 15.0 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 7.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.9 22.9 GO:0032982 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.8 5.7 GO:0008091 spectrin(GO:0008091)
0.8 3.2 GO:0032280 symmetric synapse(GO:0032280)
0.8 3.8 GO:0031523 Myb complex(GO:0031523)
0.7 2.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 3.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 4.3 GO:0016460 myosin II complex(GO:0016460)
0.4 1.2 GO:0005607 laminin-2 complex(GO:0005607)
0.4 1.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.4 1.1 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.3 6.5 GO:0031045 dense core granule(GO:0031045)
0.3 1.3 GO:0033269 internode region of axon(GO:0033269)
0.3 2.4 GO:1990357 terminal web(GO:1990357)
0.3 1.2 GO:0008623 CHRAC(GO:0008623)
0.3 0.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.3 14.6 GO:0016459 myosin complex(GO:0016459)
0.2 4.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 2.9 GO:0043219 lateral loop(GO:0043219)
0.2 2.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 0.6 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 6.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 0.5 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.2 1.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 12.9 GO:0009925 basal plasma membrane(GO:0009925)
0.2 4.6 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 9.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.4 GO:0031527 filopodium membrane(GO:0031527)
0.1 22.3 GO:0042383 sarcolemma(GO:0042383)
0.1 4.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 2.5 GO:0010369 chromocenter(GO:0010369)
0.1 0.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 20.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 14.6 GO:0001726 ruffle(GO:0001726)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.7 GO:0042588 zymogen granule(GO:0042588)
0.1 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 3.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 5.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 5.0 GO:0055037 recycling endosome(GO:0055037)
0.0 3.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 2.2 GO:0016234 inclusion body(GO:0016234)
0.0 1.1 GO:0043292 contractile fiber(GO:0043292)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 2.9 GO:0043197 dendritic spine(GO:0043197)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 6.8 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.0 17.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.3 10.4 GO:0050786 RAGE receptor binding(GO:0050786)
1.3 15.1 GO:0030274 LIM domain binding(GO:0030274)
1.0 4.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.0 2.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.9 13.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.9 4.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.8 3.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 2.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.6 1.9 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.6 2.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.5 1.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.5 3.7 GO:0030172 troponin C binding(GO:0030172)
0.5 21.9 GO:0030552 cAMP binding(GO:0030552)
0.4 4.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.4 2.8 GO:0001515 opioid peptide activity(GO:0001515)
0.4 1.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.4 1.1 GO:0042936 dipeptide transporter activity(GO:0042936)
0.4 1.9 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 3.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 3.0 GO:0034711 inhibin binding(GO:0034711)
0.3 2.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 5.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 5.1 GO:0030553 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 2.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 1.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 1.7 GO:0031433 telethonin binding(GO:0031433)
0.3 10.1 GO:0030506 ankyrin binding(GO:0030506)
0.3 1.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 3.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 4.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.7 GO:0031432 titin binding(GO:0031432)
0.2 2.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 3.7 GO:0043495 protein anchor(GO:0043495)
0.2 2.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.7 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 2.7 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 8.1 GO:0003785 actin monomer binding(GO:0003785)
0.2 9.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.4 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.2 0.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 6.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 0.5 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.1 3.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.7 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 1.9 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 2.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.9 GO:0071253 connexin binding(GO:0071253)
0.1 8.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 2.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 13.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.3 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.5 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.7 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 1.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0052744 phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 3.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 3.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 5.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 3.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.8 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 10.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.0 GO:0046332 SMAD binding(GO:0046332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 4.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 5.1 PID CONE PATHWAY Visual signal transduction: Cones
0.2 6.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 8.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 4.7 PID RHOA PATHWAY RhoA signaling pathway
0.1 5.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 6.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 9.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 5.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 2.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 15.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 24.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 3.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 2.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 4.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 2.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 10.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.2 3.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 3.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 5.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 5.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 3.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 6.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 3.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.8 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)