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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for UCACAGU
Z-value: 0.84
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miRNA associated with seed UCACAGU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_122961173 Show fit | 3.44 |
ENSMUST00000030408.5
ENSMUST00000127047.1 |
major facilitator superfamily domain containing 2A |
|
| chr2_+_102658640 Show fit | 3.38 |
ENSMUST00000080210.3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
|
| chr10_-_109010955 Show fit | 2.44 |
ENSMUST00000105276.1
ENSMUST00000064054.7 |
synaptotagmin I |
|
| chr4_-_105109829 Show fit | 2.08 |
ENSMUST00000030243.7
|
protein kinase, AMP-activated, alpha 2 catalytic subunit |
|
| chr10_+_87859255 Show fit | 1.92 |
ENSMUST00000105300.2
|
insulin-like growth factor 1 |
|
| chr5_+_73491026 Show fit | 1.77 |
ENSMUST00000063882.5
ENSMUST00000113558.1 |
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae) |
|
| chr16_-_46010212 Show fit | 1.67 |
ENSMUST00000130481.1
|
phosphatidylinositol-specific phospholipase C, X domain containing 2 |
|
| chr16_+_44173239 Show fit | 1.49 |
ENSMUST00000119746.1
|
predicted gene 608 |
|
| chr14_+_17660956 Show fit | 1.40 |
ENSMUST00000022303.7
ENSMUST00000091471.4 |
thyroid hormone receptor beta |
|
| chr6_+_17463749 Show fit | 1.36 |
ENSMUST00000115443.1
|
met proto-oncogene |
Network of associatons between targets according to the STRING database.
First level regulatory network of UCACAGU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0051977 | lysophospholipid transport(GO:0051977) |
| 0.5 | 3.4 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 2.7 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 0.1 | 2.6 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.2 | 2.2 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.3 | 1.9 | GO:1904073 | regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.1 | 1.6 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.4 | 1.4 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.2 | 1.4 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.1 | 1.4 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 2.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 1.9 | GO:0042567 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 1.9 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.7 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 1.7 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 1.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.4 | 1.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.3 | 1.3 | GO:0070876 | SOSS complex(GO:0070876) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.4 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 3.4 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.3 | 2.7 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.1 | 2.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.6 | 2.4 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.2 | 2.1 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.1 | 2.1 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 2.1 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 1.8 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 1.8 | GO:0097602 | cullin family protein binding(GO:0097602) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 3.4 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 3.4 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 2.3 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 2.3 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.8 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.3 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.2 | PID BMP PATHWAY | BMP receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.6 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 3.0 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.2 | 2.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 2.2 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 2.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 1.8 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 1.7 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 1.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 1.7 | REACTOME PKB MEDIATED EVENTS | Genes involved in PKB-mediated events |
| 0.0 | 1.3 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |