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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Vsx2_Dlx3

Z-value: 1.50

Motif logo

Transcription factors associated with Vsx2_Dlx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000021239.6 visual system homeobox 2
ENSMUSG00000001510.7 distal-less homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dlx3mm10_v2_chr11_+_95120089_951201250.555.1e-04Click!
Vsx2mm10_v2_chr12_+_84569762_845698400.221.9e-01Click!

Activity profile of Vsx2_Dlx3 motif

Sorted Z-values of Vsx2_Dlx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_168767136 12.44 ENSMUST00000029061.5
ENSMUST00000103074.1
sal-like 4 (Drosophila)
chr2_-_168767029 9.87 ENSMUST00000075044.3
sal-like 4 (Drosophila)
chr4_+_34893772 9.18 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr12_+_109545390 7.71 ENSMUST00000146701.1
maternally expressed 3
chr14_+_27000362 7.08 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr2_+_84734050 6.39 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr16_-_42340595 5.94 ENSMUST00000102817.4
growth associated protein 43
chr3_-_116253467 5.53 ENSMUST00000090473.5
G-protein coupled receptor 88
chr3_+_51661167 5.41 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr19_+_38132767 5.20 ENSMUST00000025956.5
ENSMUST00000112329.1
phosphodiesterase 6C, cGMP specific, cone, alpha prime
chr6_+_30541582 4.83 ENSMUST00000096066.4
carboxypeptidase A2, pancreatic
chr17_-_28560704 4.52 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr10_+_75564086 4.24 ENSMUST00000141062.1
ENSMUST00000152657.1
gamma-glutamyltransferase 1
chr7_-_100855403 3.47 ENSMUST00000156855.1
RELT tumor necrosis factor receptor
chr14_+_99298652 3.20 ENSMUST00000005279.6
Kruppel-like factor 5
chr4_-_99654983 3.15 ENSMUST00000136525.1
predicted gene 12688
chr11_+_62077018 2.82 ENSMUST00000092415.5
sperm antigen with calponin homology and coiled-coil domains 1
chr15_-_79285502 2.80 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr1_+_172555932 2.62 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr1_-_79440039 2.60 ENSMUST00000049972.4
secretogranin II
chr10_-_6980376 2.17 ENSMUST00000105617.1
interaction protein for cytohesin exchange factors 1
chr14_+_32321987 2.14 ENSMUST00000022480.7
oxoglutarate dehydrogenase-like
chr3_-_130730375 2.13 ENSMUST00000079085.6
ribosomal protein L34
chr4_+_5724304 1.97 ENSMUST00000108380.1
family with sequence similarity 110, member B
chr12_+_108605757 1.83 ENSMUST00000109854.2
Ena-vasodilator stimulated phosphoprotein
chr6_-_102464667 1.78 ENSMUST00000032159.6
contactin 3
chr2_-_121235689 1.71 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr12_+_38780284 1.70 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr17_+_35533194 1.64 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr3_+_159839729 1.63 ENSMUST00000068952.5
wntless homolog (Drosophila)
chr4_-_132510493 1.57 ENSMUST00000030724.8
sestrin 2
chr7_-_115846080 1.43 ENSMUST00000166207.1
SRY-box containing gene 6
chr9_+_119063429 1.41 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr15_-_34356421 1.37 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr7_+_126950518 1.37 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chr15_+_81936753 1.36 ENSMUST00000038757.7
cold shock domain containing C2, RNA binding
chr3_-_130730310 1.35 ENSMUST00000062601.7
ribosomal protein L34
chr4_-_41464816 1.34 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
kinesin family member 24
chr6_-_136781718 1.29 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chr15_+_81936911 1.28 ENSMUST00000135663.1
cold shock domain containing C2, RNA binding
chr2_+_69219971 1.28 ENSMUST00000005364.5
ENSMUST00000112317.2
glucose-6-phosphatase, catalytic, 2
chr2_+_127909058 1.28 ENSMUST00000110344.1
acyl-Coenzyme A oxidase-like
chr16_-_89818338 1.25 ENSMUST00000164263.2
T cell lymphoma invasion and metastasis 1
chr3_-_17230976 1.25 ENSMUST00000177874.1
predicted gene 5283
chr7_-_116031047 1.24 ENSMUST00000106612.1
SRY-box containing gene 6
chr7_+_144838590 1.23 ENSMUST00000105898.1
fibroblast growth factor 3
chr19_-_47692042 1.23 ENSMUST00000026045.7
ENSMUST00000086923.5
collagen, type XVII, alpha 1
chr1_-_172027251 1.22 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr17_-_67950908 1.21 ENSMUST00000164647.1
Rho GTPase activating protein 28
chr7_+_126950687 1.19 ENSMUST00000106333.1
seizure related 6 homolog like 2
chr12_+_38780817 1.14 ENSMUST00000160856.1
ets variant gene 1
chr2_-_116067391 1.11 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr5_-_122989260 1.11 ENSMUST00000118027.1
lysine (K)-specific demethylase 2B
chr15_-_101694299 1.05 ENSMUST00000023788.6
keratin 6A
chr17_-_24073479 1.03 ENSMUST00000017090.5
potassium channel tetramerisation domain containing 5
chr1_-_172027269 1.03 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr5_+_27261916 1.00 ENSMUST00000101471.3
dipeptidylpeptidase 6
chr9_+_53771499 0.97 ENSMUST00000048670.8
solute carrier family 35, member F2
chr4_+_134068429 0.97 ENSMUST00000121391.1
absent in melanoma 1-like
chr11_-_106301801 0.94 ENSMUST00000103071.3
growth hormone
chr11_+_29373618 0.92 ENSMUST00000040182.6
ENSMUST00000109477.1
coiled coil domain containing 88A
chr12_+_38781093 0.92 ENSMUST00000161513.1
ets variant gene 1
chr18_+_37518341 0.92 ENSMUST00000097609.1
protocadherin beta 22
chrX_+_112093496 0.91 ENSMUST00000130247.2
ENSMUST00000038546.6
testis expressed gene 16
chrX_+_140956892 0.89 ENSMUST00000112971.1
autophagy related 4A, cysteine peptidase
chr8_+_57320975 0.89 ENSMUST00000040104.3
heart and neural crest derivatives expressed transcript 2
chr7_+_126950837 0.89 ENSMUST00000106332.1
seizure related 6 homolog like 2
chr19_-_5560570 0.89 ENSMUST00000025861.1
OVO homolog-like 1 (Drosophila)
chr2_+_49787675 0.88 ENSMUST00000028103.6
LY6/PLAUR domain containing 6B
chr3_-_50443603 0.84 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr2_-_7395879 0.81 ENSMUST00000182404.1
CUGBP, Elav-like family member 2
chr3_-_49757257 0.80 ENSMUST00000035931.7
protocadherin 18
chr9_-_120068263 0.79 ENSMUST00000064165.3
ENSMUST00000177637.1
chemokine (C-X3-C) receptor 1
chr9_-_21312255 0.77 ENSMUST00000115433.3
ENSMUST00000003397.7
adaptor protein complex AP-1, mu 2 subunit
chr4_-_83052147 0.74 ENSMUST00000170248.2
Fras1 related extracellular matrix protein 1
chr4_-_83052229 0.73 ENSMUST00000107230.1
Fras1 related extracellular matrix protein 1
chr7_+_66839752 0.71 ENSMUST00000107478.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr2_-_59948155 0.70 ENSMUST00000153136.1
bromodomain adjacent to zinc finger domain, 2B
chr16_+_34690548 0.70 ENSMUST00000023532.6
coiled-coil domain containing 14
chr10_+_69787431 0.68 ENSMUST00000183240.1
ankyrin 3, epithelial
chr15_+_98571004 0.67 ENSMUST00000023728.6
RIKEN cDNA 4930415O20 gene
chr18_+_23415400 0.66 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr12_+_99964499 0.65 ENSMUST00000177549.1
ENSMUST00000160413.1
ENSMUST00000162221.1
ENSMUST00000049788.8
potassium channel, subfamily K, member 13
chr7_+_66839726 0.65 ENSMUST00000098382.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr11_+_101987050 0.64 ENSMUST00000010985.7
RIKEN cDNA 1700006E09 gene
chr9_+_18427543 0.62 ENSMUST00000053326.9
predicted gene 5612
chrX_+_106583184 0.61 ENSMUST00000101296.2
ENSMUST00000101297.3
predicted gene 5127
chr14_+_76504478 0.61 ENSMUST00000022587.9
ENSMUST00000134109.1
TSC22 domain family, member 1
chr12_+_52699297 0.61 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr18_+_82914632 0.60 ENSMUST00000071233.6
zinc finger protein 516
chr17_+_17402672 0.57 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr1_-_134955908 0.57 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr10_-_28986280 0.54 ENSMUST00000152363.1
ENSMUST00000015663.6
RIKEN cDNA 2310057J18 gene
chr5_-_115652974 0.52 ENSMUST00000121746.1
ENSMUST00000118576.1
coiled-coil domain containing 64
chr2_+_153938218 0.52 ENSMUST00000109757.1
BPI fold containing family B, member 4
chr11_-_71144704 0.50 ENSMUST00000108518.2
NLR family, pyrin domain containing 1A
chr17_-_35697971 0.50 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr18_+_44104407 0.49 ENSMUST00000081271.5
serine peptidase inhibitor, Kazal type 11
chr14_+_76504185 0.48 ENSMUST00000177207.1
TSC22 domain family, member 1
chr4_+_8690399 0.48 ENSMUST00000127476.1
chromodomain helicase DNA binding protein 7
chr2_+_127854628 0.47 ENSMUST00000028859.1
acyl-Coenzyme A oxidase-like
chrX_+_164162167 0.47 ENSMUST00000131543.1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr1_-_134955847 0.45 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr17_-_70998010 0.45 ENSMUST00000024846.6
myosin, light chain 12A, regulatory, non-sarcomeric
chr8_-_3624989 0.44 ENSMUST00000142431.1
Purkinje cell protein 2 (L7)
chr6_-_116716888 0.44 ENSMUST00000056623.6
transmembrane protein 72
chr5_-_104077608 0.41 ENSMUST00000164471.1
ENSMUST00000178967.1
predicted gene, 17660
chr5_+_14025305 0.41 ENSMUST00000073957.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_-_57653023 0.41 ENSMUST00000034021.5
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr2_+_36230426 0.41 ENSMUST00000062069.5
prostaglandin-endoperoxide synthase 1
chr13_-_102906046 0.39 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr13_+_118714678 0.37 ENSMUST00000022246.8
fibroblast growth factor 10
chr8_-_120228221 0.33 ENSMUST00000183235.1
RIKEN cDNA A330074K22 gene
chr9_-_37147257 0.33 ENSMUST00000039674.5
ENSMUST00000080754.5
Pbx/knotted 1 homeobox 2
chr8_-_34965631 0.33 ENSMUST00000033929.4
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr4_+_62583568 0.33 ENSMUST00000098031.3
regulator of G-protein signaling 3
chr4_+_110397764 0.31 ENSMUST00000097920.2
ENSMUST00000080744.6
ATP/GTP binding protein-like 4
chr9_-_79977782 0.31 ENSMUST00000093811.4
filamin A interacting protein 1
chr8_-_3625274 0.29 ENSMUST00000004749.6
Purkinje cell protein 2 (L7)
chr4_+_110397661 0.29 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr1_-_158356258 0.26 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr4_-_155056784 0.26 ENSMUST00000131173.2
phospholipase C, eta 2
chr10_-_53647080 0.26 ENSMUST00000169866.1
family with sequence similarity 184, member A
chr1_-_78968079 0.25 ENSMUST00000049117.5
predicted pseudogene 5830
chr2_-_33086366 0.25 ENSMUST00000049618.2
GTPase activating RANGAP domain-like 3
chr7_+_123123870 0.25 ENSMUST00000094053.5
trinucleotide repeat containing 6a
chr7_+_79273201 0.24 ENSMUST00000037315.6
abhydrolase domain containing 2
chr5_+_138187485 0.24 ENSMUST00000110934.2
canopy 4 homolog (zebrafish)
chr2_-_7396192 0.24 ENSMUST00000137733.2
CUGBP, Elav-like family member 2
chr3_-_33844255 0.23 ENSMUST00000029222.5
coiled-coil domain containing 39
chr2_-_79456750 0.21 ENSMUST00000041099.4
neurogenic differentiation 1
chr1_+_53061637 0.21 ENSMUST00000027269.5
myostatin
chr17_-_45733843 0.20 ENSMUST00000178179.1
RIKEN cDNA 1600014C23 gene
chr8_-_3625541 0.19 ENSMUST00000136105.1
Purkinje cell protein 2 (L7)
chr12_-_24493656 0.19 ENSMUST00000073088.2
predicted pseudogene 16372
chr1_+_161494649 0.19 ENSMUST00000086084.1
tumor necrosis factor (ligand) superfamily, member 18
chr7_+_46376467 0.18 ENSMUST00000072514.1
myogenic differentiation 1
chr19_+_5088534 0.17 ENSMUST00000025811.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr15_+_101473472 0.17 ENSMUST00000088049.3
keratin 86
chr17_+_37529957 0.17 ENSMUST00000097325.3
olfactory receptor 111
chr15_+_81744848 0.17 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr3_+_55782500 0.16 ENSMUST00000075422.4
mab-21-like 1 (C. elegans)
chr4_+_154964117 0.15 ENSMUST00000030931.4
ENSMUST00000070953.4
pantothenate kinase 4
chr2_+_9882622 0.14 ENSMUST00000114919.1
RIKEN cDNA 4930412O13 gene
chr7_+_64185459 0.13 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
transient receptor potential cation channel, subfamily M, member 1
chr6_+_77242644 0.13 ENSMUST00000159616.1
leucine rich repeat transmembrane neuronal 1
chr18_+_37300799 0.12 ENSMUST00000051754.1
protocadherin beta 3
chr18_+_77332394 0.12 ENSMUST00000148341.1
lipoxygenase homology domains 1
chr12_-_104473236 0.11 ENSMUST00000021513.4
goosecoid homeobox
chr2_-_7395968 0.11 ENSMUST00000002176.6
CUGBP, Elav-like family member 2
chr12_-_11208948 0.10 ENSMUST00000049877.1
mesogenin 1
chr18_+_69346143 0.09 ENSMUST00000114980.1
transcription factor 4
chr11_-_102579071 0.09 ENSMUST00000107080.1
predicted gene 11627
chr5_-_137531952 0.09 ENSMUST00000140139.1
guanine nucleotide binding protein (G protein), beta 2
chr1_-_72874877 0.08 ENSMUST00000027377.8
insulin-like growth factor binding protein 5
chr7_-_5014645 0.08 ENSMUST00000165320.1
Flt3 interacting zinc finger protein 1
chr1_-_84839304 0.08 ENSMUST00000027421.6
thyroid hormone receptor interactor 12
chr18_+_24603952 0.07 ENSMUST00000025120.6
elongator acetyltransferase complex subunit 2
chr11_-_65269941 0.07 ENSMUST00000102635.3
myocardin
chrX_-_112406779 0.07 ENSMUST00000026601.2
spermidine/spermine N1-acetyl transferase-like 1
chr3_+_138065052 0.06 ENSMUST00000163080.2
RIKEN cDNA 1110002E22 gene
chr13_-_100616911 0.04 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
MARVEL (membrane-associating) domain containing 2
chr2_-_27475622 0.04 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
bromodomain containing 3
chr4_-_94928820 0.04 ENSMUST00000107097.2
equatorin, sperm acrosome associated
chr2_+_71528657 0.03 ENSMUST00000126400.1
distal-less homeobox 1
chr11_-_102579461 0.02 ENSMUST00000107081.1
predicted gene 11627
chr6_-_129775849 0.01 ENSMUST00000095409.2
predicted gene 156
chr13_-_102905740 0.01 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr1_+_66468364 0.00 ENSMUST00000061620.9
unc-80 homolog (C. elegans)
chr17_-_81065056 0.00 ENSMUST00000025093.4
THUMP domain containing 2
chr18_-_65970178 0.00 ENSMUST00000025397.5
complexin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Vsx2_Dlx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0061743 motor learning(GO:0061743)
1.2 22.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.9 8.7 GO:0030916 otic vesicle formation(GO:0030916)
0.7 2.2 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.7 5.9 GO:0016198 axon choice point recognition(GO:0016198)
0.7 9.2 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.5 1.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.5 4.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.5 1.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 5.2 GO:0046549 retinal cone cell development(GO:0046549)
0.4 1.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.4 5.4 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.3 4.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 1.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 0.9 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 2.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 7.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 3.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 1.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 2.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.9 GO:0051697 protein delipidation(GO:0051697)
0.2 0.8 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 1.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 2.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 5.5 GO:0032094 response to food(GO:0032094)
0.1 3.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.5 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 1.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.6 GO:1902261 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.9 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.1 1.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0002309 T cell proliferation involved in immune response(GO:0002309) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0060287 regulation of cilium beat frequency(GO:0003356) determination of pancreatic left/right asymmetry(GO:0035469) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.1 GO:0045109 negative regulation of growth of symbiont involved in interaction with host(GO:0044146) intermediate filament organization(GO:0045109)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.4 GO:0051693 actin filament capping(GO:0051693)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 2.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:2000722 regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.0 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.6 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 3.5 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0060187 cell pole(GO:0060187)
0.3 0.9 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 5.9 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.8 GO:0071439 clathrin complex(GO:0071439)
0.2 2.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 0.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 22.3 GO:0000792 heterochromatin(GO:0000792)
0.1 2.6 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0060091 kinocilium(GO:0060091)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 3.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.9 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0061702 inflammasome complex(GO:0061702)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0016460 myosin II complex(GO:0016460)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0031672 A band(GO:0031672)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 5.3 GO:0005635 nuclear envelope(GO:0005635)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.7 5.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.4 1.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4 4.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 2.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 1.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.6 GO:0070728 leucine binding(GO:0070728)
0.2 5.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 5.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 1.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 0.8 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 3.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 8.1 GO:0005179 hormone activity(GO:0005179)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 33.7 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 6.2 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 19.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 5.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 9.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 9.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.6 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 3.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 3.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism