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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb7c

Z-value: 0.95

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Transcription factors associated with Zbtb7c

Gene Symbol Gene ID Gene Info
Zbtb7c
ENSMUSG00000044646.8 zinc finger and BTB domain containing 7C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb7cmm10_v2_chr18_+_76059458_760595010.554.7e-04Click!

Activity profile of Zbtb7c motif

Sorted Z-values of Zbtb7c motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_100135928 4.73 ENSMUST00000107411.2
Krt15
keratin 15
chr12_-_76709997 4.31 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr11_-_100207507 3.44 ENSMUST00000007272.7
Krt14
keratin 14
chr2_+_157560078 3.22 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat
neuronatin
chr10_-_79874211 2.54 ENSMUST00000167897.1
BC005764
cDNA sequence BC005764
chr14_-_54994541 2.54 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
chr14_+_118854695 2.49 ENSMUST00000100314.3
Cldn10
claudin 10
chr2_-_180642681 2.49 ENSMUST00000037877.10
Tcfl5
transcription factor-like 5 (basic helix-loop-helix)
chr11_+_53519871 2.41 ENSMUST00000120878.2
Sept8
septin 8
chr11_+_53519920 2.32 ENSMUST00000147912.1
Sept8
septin 8
chr9_-_108190352 2.29 ENSMUST00000035208.7
Bsn
bassoon
chr11_+_80089385 2.28 ENSMUST00000108239.1
ENSMUST00000017694.5
Atad5
ATPase family, AAA domain containing 5
chr4_-_108383349 2.18 ENSMUST00000053157.6
Fam159a
family with sequence similarity 159, member A
chr12_-_109068173 2.16 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr11_+_53519725 2.02 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8
septin 8
chr16_+_48994185 1.94 ENSMUST00000117994.1
ENSMUST00000048374.5
C330027C09Rik
RIKEN cDNA C330027C09 gene
chr19_-_5273080 1.85 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr18_-_62179948 1.75 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr15_+_78899755 1.70 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
Sh3bp1
SH3-domain binding protein 1
chr12_+_110279228 1.60 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chrX_-_142966709 1.60 ENSMUST00000041317.2
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr19_+_7417586 1.45 ENSMUST00000159348.1
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr7_+_45639964 1.42 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr16_-_48993931 1.42 ENSMUST00000114516.1
Dzip3
DAZ interacting protein 3, zinc finger
chrX_-_7574120 1.33 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr15_-_82212796 1.29 ENSMUST00000179269.1
AI848285
expressed sequence AI848285
chr15_-_101694299 1.28 ENSMUST00000023788.6
Krt6a
keratin 6A
chr17_+_47726834 1.24 ENSMUST00000024782.5
ENSMUST00000144955.1
Pgc
progastricsin (pepsinogen C)
chr18_-_35662180 1.22 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24
spermatogenesis associated 24
chr5_+_30711564 1.22 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5
chr14_-_54686060 1.18 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr8_+_109868586 1.18 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2
PH domain and leucine rich repeat protein phosphatase 2
chr5_-_136883115 1.11 ENSMUST00000057497.6
ENSMUST00000111103.1
Col26a1
collagen, type XXVI, alpha 1
chr2_-_121271315 1.08 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr3_+_107036156 1.08 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr16_-_48994081 1.06 ENSMUST00000121869.1
Dzip3
DAZ interacting protein 3, zinc finger
chr18_+_56707725 1.05 ENSMUST00000025486.8
Lmnb1
lamin B1
chr2_-_118703963 1.02 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr5_+_30711849 0.98 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5
dihydropyrimidinase-like 5
chr15_-_85581809 0.87 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr8_-_122432924 0.86 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr1_-_86388162 0.83 ENSMUST00000027440.3
Nmur1
neuromedin U receptor 1
chrX_+_36743659 0.83 ENSMUST00000047655.6
Slc25a43
solute carrier family 25, member 43
chr2_-_105399286 0.83 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr6_+_135198034 0.81 ENSMUST00000130612.1
8430419L09Rik
RIKEN cDNA 8430419L09 gene
chr11_-_100441795 0.81 ENSMUST00000107398.1
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr15_-_101850778 0.81 ENSMUST00000023790.3
Krt1
keratin 1
chr15_-_101680281 0.81 ENSMUST00000023786.5
Krt6b
keratin 6B
chr11_+_49794157 0.80 ENSMUST00000020629.4
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr4_-_120287349 0.80 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr8_+_25911670 0.79 ENSMUST00000120653.1
ENSMUST00000126226.1
Kcnu1
potassium channel, subfamily U, member 1
chr1_-_153332724 0.77 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr10_-_93589621 0.76 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr11_+_68432112 0.75 ENSMUST00000021283.7
Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr13_-_55513427 0.74 ENSMUST00000069929.6
ENSMUST00000069968.6
ENSMUST00000131306.1
ENSMUST00000046246.6
Pdlim7
PDZ and LIM domain 7
chr12_-_110840905 0.73 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30
serine/threonine kinase 30
chr5_+_122158265 0.72 ENSMUST00000102528.4
ENSMUST00000086294.6
Ppp1cc
protein phosphatase 1, catalytic subunit, gamma isoform
chr1_-_21961581 0.72 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr1_-_45890078 0.71 ENSMUST00000183590.1
Gm5269
predicted gene 5269
chr12_+_31265234 0.71 ENSMUST00000169088.1
Lamb1
laminin B1
chr16_+_11984581 0.71 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9
shisa homolog 9 (Xenopus laevis)
chr17_+_34894515 0.67 ENSMUST00000052778.8
Zbtb12
zinc finger and BTB domain containing 12
chr9_-_85327110 0.67 ENSMUST00000034802.8
Fam46a
family with sequence similarity 46, member A
chr14_+_25607797 0.65 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr5_-_148928619 0.62 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1
katanin p60 subunit A-like 1
chr8_+_72240052 0.61 ENSMUST00000145213.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr11_+_101176041 0.60 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr2_+_158794807 0.60 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr11_+_115564434 0.60 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr12_+_31265279 0.59 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1
laminin B1
chr8_+_72240315 0.58 ENSMUST00000126885.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr3_+_134236483 0.58 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4
CXXC finger 4
chr19_-_41848076 0.57 ENSMUST00000059231.2
Frat2
frequently rearranged in advanced T cell lymphomas 2
chr14_-_54686605 0.57 ENSMUST00000147714.1
Acin1
apoptotic chromatin condensation inducer 1
chr11_+_70000578 0.57 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr8_+_72240018 0.56 ENSMUST00000003117.8
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr19_-_53371766 0.56 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr7_+_5056856 0.56 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106
coiled-coil domain containing 106
chr5_-_134614953 0.55 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2
linker for activation of T cells family, member 2
chr7_-_6331235 0.55 ENSMUST00000127658.1
ENSMUST00000062765.7
Zfp583
zinc finger protein 583
chr2_-_121271403 0.52 ENSMUST00000110648.1
Trp53bp1
transformation related protein 53 binding protein 1
chr1_-_165460430 0.51 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr11_-_115514374 0.49 ENSMUST00000021083.6
Hn1
hematological and neurological expressed sequence 1
chr7_+_5056706 0.48 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr18_+_86394952 0.47 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr1_+_55406163 0.46 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr2_-_121271341 0.44 ENSMUST00000110647.1
Trp53bp1
transformation related protein 53 binding protein 1
chr4_+_8691303 0.41 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr14_-_67008834 0.40 ENSMUST00000111115.1
ENSMUST00000022634.8
Bnip3l
BCL2/adenovirus E1B interacting protein 3-like
chr7_-_19310035 0.40 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr18_+_34777008 0.39 ENSMUST00000043775.7
Kdm3b
KDM3B lysine (K)-specific demethylase 3B
chr8_-_34965631 0.38 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr19_+_40612392 0.38 ENSMUST00000134063.1
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr6_+_135197977 0.37 ENSMUST00000111915.1
ENSMUST00000111916.1
8430419L09Rik
RIKEN cDNA 8430419L09 gene
chr11_+_75532127 0.36 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr2_-_45117349 0.35 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_85035487 0.35 ENSMUST00000028465.7
P2rx3
purinergic receptor P2X, ligand-gated ion channel, 3
chr7_-_19715395 0.35 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr2_-_13793793 0.34 ENSMUST00000003509.8
St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr2_-_32312162 0.34 ENSMUST00000155269.1
Dnm1
dynamin 1
chrX_+_20617503 0.33 ENSMUST00000115375.1
ENSMUST00000115374.1
ENSMUST00000084383.3
Rbm10
RNA binding motif protein 10
chr9_+_67840386 0.32 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr2_+_121955964 0.31 ENSMUST00000036647.6
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr11_-_102447647 0.30 ENSMUST00000049057.4
Fam171a2
family with sequence similarity 171, member A2
chrX_-_41911877 0.28 ENSMUST00000047037.8
Thoc2
THO complex 2
chr9_+_66350465 0.28 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr12_+_110841021 0.25 ENSMUST00000181348.1
4921507G05Rik
RIKEN cDNA 4921507G05 gene
chr18_-_61400363 0.24 ENSMUST00000063307.5
ENSMUST00000075299.6
Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr7_-_13038201 0.24 ENSMUST00000005714.7
ENSMUST00000156389.1
ENSMUST00000165394.2
Ube2m
ubiquitin-conjugating enzyme E2M
chr1_+_136018062 0.23 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr8_+_33386325 0.20 ENSMUST00000078058.3
ENSMUST00000070340.4
Purg
purine-rich element binding protein G
chr10_+_111164794 0.20 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8
oxysterol binding protein-like 8
chr11_+_75531690 0.19 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2
solute carrier family 43, member 2
chr10_-_79766872 0.18 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chr16_+_17561885 0.18 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6
purinergic receptor P2X, ligand-gated ion channel, 6
chr18_-_5334364 0.15 ENSMUST00000063989.5
Zfp438
zinc finger protein 438
chr11_+_85832551 0.14 ENSMUST00000000095.6
Tbx2
T-box 2
chrX_-_72274747 0.14 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr5_+_108268897 0.13 ENSMUST00000031190.4
Dr1
down-regulator of transcription 1
chr2_-_72980402 0.12 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3
trans-acting transcription factor 3
chrX_+_152233228 0.11 ENSMUST00000112588.2
ENSMUST00000082177.6
Kdm5c
lysine (K)-specific demethylase 5C
chr12_+_29938036 0.11 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn
peroxidasin homolog (Drosophila)
chr4_-_128962420 0.11 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
Adc
arginine decarboxylase
chr3_+_87906321 0.10 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr4_-_116821501 0.10 ENSMUST00000055436.3
Hpdl
4-hydroxyphenylpyruvate dioxygenase-like
chr2_-_119477613 0.07 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80
INO80 homolog (S. cerevisiae)
chr12_-_76369586 0.07 ENSMUST00000176278.1
Zbtb25
zinc finger and BTB domain containing 25
chr11_-_71004387 0.06 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr8_+_95825353 0.05 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr12_-_76369385 0.04 ENSMUST00000176187.1
ENSMUST00000167011.1
ENSMUST00000176967.1
Zbtb25
zinc finger and BTB domain containing 25
chr5_-_137786651 0.03 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr10_+_93589413 0.02 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr5_-_137786681 0.02 ENSMUST00000132726.1
Mepce
methylphosphate capping enzyme
chr3_-_96727453 0.01 ENSMUST00000141377.1
ENSMUST00000125183.1
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb7c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.5 2.5 GO:0031444 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5 3.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.4 1.8 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.4 1.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.3 1.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 0.9 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.2 1.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 1.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 0.9 GO:0072054 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.2 1.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 1.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 2.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.6 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1 2.0 GO:0045830 positive regulation of isotype switching(GO:0045830) negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 1.7 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 1.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 2.1 GO:0045109 intermediate filament organization(GO:0045109)
0.1 4.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.8 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 0.4 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.4 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 3.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 2.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.9 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.8 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.3 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 2.4 GO:0071805 potassium ion transmembrane transport(GO:0071805)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.6 4.3 GO:0008091 spectrin(GO:0008091)
0.5 2.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.3 2.5 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 1.8 GO:0061574 ASAP complex(GO:0061574)
0.2 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 5.5 GO:0045095 keratin filament(GO:0045095)
0.2 0.8 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.2 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 2.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 2.5 GO:0032982 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 3.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 7.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:1990254 keratin filament binding(GO:1990254)
0.5 1.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.4 1.8 GO:0004939 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.3 2.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.3 GO:2001069 glycogen binding(GO:2001069)
0.2 2.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 2.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 4.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 4.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 5.8 GO:0005525 GTP binding(GO:0005525)
0.0 2.2 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions