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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zfp105

Z-value: 0.31

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Transcription factors associated with Zfp105

Gene Symbol Gene ID Gene Info
Zfp105
ENSMUSG00000057895.5 zinc finger protein 105

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_1229230990.019.8e-01Click!

Activity profile of Zfp105 motif

Sorted Z-values of Zfp105 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_39886730 0.94 ENSMUST00000168838.1
Cyp2c69
cytochrome P450, family 2, subfamily c, polypeptide 69
chr11_+_44617310 0.72 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1
early B cell factor 1
chr11_+_104550663 0.54 ENSMUST00000018800.2
Myl4
myosin, light polypeptide 4
chr10_-_96409038 0.51 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr19_-_39649046 0.48 ENSMUST00000067328.6
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr6_-_117214048 0.47 ENSMUST00000170447.1
Rpl28-ps4
ribosomal protein L28, pseudogene 4
chr15_+_85510812 0.39 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr1_+_171419027 0.38 ENSMUST00000171362.1
Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr15_+_99006056 0.34 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr5_-_111761697 0.30 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik
RIKEN cDNA E130006D01 gene
chr10_+_128267997 0.27 ENSMUST00000050901.2
Apof
apolipoprotein F
chr5_+_17574268 0.22 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_11008458 0.22 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr14_+_11227511 0.21 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr14_-_106101157 0.21 ENSMUST00000169588.1
Gm4775
predicted gene 4775
chr9_-_117251801 0.20 ENSMUST00000172564.1
Rbms3
RNA binding motif, single stranded interacting protein
chr6_-_99632376 0.19 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr5_+_13399309 0.17 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_-_53464721 0.15 ENSMUST00000180489.1
5830416P10Rik
RIKEN cDNA 5830416P10 gene
chr8_-_106573461 0.15 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr1_-_184732444 0.15 ENSMUST00000174257.1
Hlx
H2.0-like homeobox
chr9_-_78378725 0.14 ENSMUST00000034900.7
Ooep
oocyte expressed protein
chr12_-_83984849 0.14 ENSMUST00000164935.2
Gm17673
predicted gene, 17673
chr1_-_184732616 0.13 ENSMUST00000048572.6
Hlx
H2.0-like homeobox
chr1_+_58113136 0.13 ENSMUST00000040999.7
Aox3
aldehyde oxidase 3
chr12_+_34984748 0.13 ENSMUST00000134550.2
Prps1l1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr8_-_109251698 0.13 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr9_+_58134535 0.12 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6
stimulated by retinoic acid gene 6
chr15_-_81843699 0.11 ENSMUST00000092020.2
Gm8444
predicted gene 8444
chr2_-_151476153 0.11 ENSMUST00000080132.2
4921509C19Rik
RIKEN cDNA 4921509C19 gene
chr11_-_100411874 0.11 ENSMUST00000141840.1
Leprel4
leprecan-like 4
chr13_-_21501418 0.11 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr10_-_128549102 0.10 ENSMUST00000176906.1
Rpl41
ribosomal protein L41
chr2_-_177267036 0.10 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr2_-_91931774 0.10 ENSMUST00000069423.6
Mdk
midkine
chr4_-_49549523 0.09 ENSMUST00000029987.9
Aldob
aldolase B, fructose-bisphosphate
chr9_-_19928282 0.08 ENSMUST00000082002.5
Gm7808
predicted pseudogene 7808
chr1_+_156366037 0.08 ENSMUST00000102782.3
Gm2000
predicted gene 2000
chr8_+_93810832 0.07 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1
guanine nucleotide binding protein, alpha O
chr15_+_78983041 0.07 ENSMUST00000109687.1
ENSMUST00000109688.1
ENSMUST00000130663.2
Triobp
TRIO and F-actin binding protein
chr11_-_103363431 0.07 ENSMUST00000092557.5
Arhgap27
Rho GTPase activating protein 27
chr5_+_19907502 0.06 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_37484955 0.06 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr7_-_116084635 0.06 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr5_+_138363719 0.06 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr4_-_3973581 0.05 ENSMUST00000089430.4
Gm11808
predicted gene 11808
chr5_+_136953246 0.05 ENSMUST00000111094.1
ENSMUST00000111097.1
Fis1
fission 1 (mitochondrial outer membrane) homolog (yeast)
chr11_+_101733011 0.05 ENSMUST00000129741.1
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr6_-_53820764 0.05 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr6_-_127151044 0.04 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr4_+_144892813 0.04 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_105157339 0.04 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr8_+_57488053 0.03 ENSMUST00000180690.1
2500002B13Rik
RIKEN cDNA 2500002B13 gene
chr1_-_63114516 0.03 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chr18_+_35829798 0.03 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr7_+_66109474 0.03 ENSMUST00000036372.6
Chsy1
chondroitin sulfate synthase 1
chr5_+_86071734 0.03 ENSMUST00000031171.7
Stap1
signal transducing adaptor family member 1
chr13_+_44439722 0.03 ENSMUST00000182568.1
1700029N11Rik
RIKEN cDNA 1700029N11 gene
chr11_-_101466222 0.03 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr11_+_108920342 0.02 ENSMUST00000052915.7
Axin2
axin2
chr8_-_79399513 0.01 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
Smad1
SMAD family member 1
chr15_+_37233036 0.00 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2
grainyhead-like 2 (Drosophila)
chr8_-_57487801 0.00 ENSMUST00000034022.3
Sap30
sin3 associated polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp105

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:0061625 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.2 GO:0010748 negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling