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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zic2

Z-value: 1.20

Motif logo

Transcription factors associated with Zic2

Gene Symbol Gene ID Gene Info
ENSMUSG00000061524.8 zinc finger protein of the cerebellum 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic2mm10_v2_chr14_+_122475397_1224754350.221.9e-01Click!

Activity profile of Zic2 motif

Sorted Z-values of Zic2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_52264323 11.13 ENSMUST00000039652.4
insulin I
chr19_+_58728887 9.47 ENSMUST00000048644.5
pancreatic lipase related protein 1
chr7_-_142679533 7.65 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
insulin II
chr6_-_41314700 5.05 ENSMUST00000064324.5
trypsin 5
chr8_-_105933832 3.96 ENSMUST00000034368.6
chymotrypsin-like
chr1_-_37719782 2.83 ENSMUST00000160589.1
RIKEN cDNA 2010300C02 gene
chr4_+_34893772 2.51 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr4_-_141846359 2.51 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr4_-_141846277 2.42 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr9_+_111019284 2.02 ENSMUST00000035077.3
lactotransferrin
chr17_-_56117265 1.97 ENSMUST00000113072.2
perilipin 5
chr4_-_4138817 1.89 ENSMUST00000133567.1
preproenkephalin
chr4_+_40920047 1.79 ENSMUST00000030122.4
serine peptidase inhibitor, Kazal type 4
chr4_+_44943727 1.78 ENSMUST00000154177.1
predicted gene 12678
chr14_-_78725089 1.62 ENSMUST00000074729.5
diacylglycerol kinase, eta
chr17_+_25298389 1.60 ENSMUST00000037453.2
protease, serine, 34
chr5_-_122002340 1.60 ENSMUST00000134326.1
cut-like homeobox 2
chr7_+_43781054 1.53 ENSMUST00000014058.9
kallikrein related-peptidase 10
chr7_-_142666816 1.52 ENSMUST00000105935.1
insulin-like growth factor 2
chr3_+_157566868 1.47 ENSMUST00000041175.6
ENSMUST00000173533.1
prostaglandin E receptor 3 (subtype EP3)
chr17_-_56117577 1.47 ENSMUST00000019808.5
perilipin 5
chr12_-_8539545 1.45 ENSMUST00000095863.3
ENSMUST00000165657.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr3_-_92588982 1.44 ENSMUST00000098888.5
sperm mitochondria-associated cysteine-rich protein
chr14_-_63509092 1.44 ENSMUST00000022522.8
L-threonine dehydrogenase
chr3_+_92316705 1.42 ENSMUST00000061038.2
small proline-rich protein 2B
chr18_+_36664060 1.42 ENSMUST00000036765.7
eukaryotic translation initiation factor 4E binding protein 3
chr8_+_109990430 1.37 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr10_+_76253848 1.37 ENSMUST00000036387.7
S100 protein, beta polypeptide, neural
chrX_+_7919816 1.35 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr5_+_100845709 1.32 ENSMUST00000144623.1
1-acylglycerol-3-phosphate O-acyltransferase 9
chr9_+_123150941 1.31 ENSMUST00000026890.4
C-type lectin domain family 3, member b
chrX_-_7978027 1.30 ENSMUST00000125418.1
GATA binding protein 1
chr7_+_26808880 1.27 ENSMUST00000040944.7
cytochrome P450, family 2, subfamily g, polypeptide 1
chr13_+_13784278 1.26 ENSMUST00000021734.7
guanine nucleotide binding protein (G protein), gamma 4
chr7_-_45615484 1.21 ENSMUST00000033099.4
fibroblast growth factor 21
chr13_-_62888282 1.12 ENSMUST00000092888.4
fructose bisphosphatase 1
chr8_-_105471481 1.09 ENSMUST00000014990.6
tubulin polymerization-promoting protein family member 3
chr11_+_84525669 1.06 ENSMUST00000126072.1
ENSMUST00000128121.1
RIKEN cDNA 1500016L03 gene
chr8_+_80494032 1.06 ENSMUST00000063359.6
glycophorin A
chr2_+_92915080 1.05 ENSMUST00000028648.2
synaptotagmin XIII
chr12_+_111971545 1.03 ENSMUST00000079009.5
tudor domain containing 9
chr13_+_30749226 1.02 ENSMUST00000021784.2
ENSMUST00000110307.1
interferon regulatory factor 4
chr11_-_12026237 1.02 ENSMUST00000150972.1
growth factor receptor bound protein 10
chr7_-_44816586 1.01 ENSMUST00000047356.8
activating transcription factor 5
chr9_+_110344185 1.00 ENSMUST00000142100.1
SREBF chaperone
chr8_+_104733997 0.99 ENSMUST00000034346.8
ENSMUST00000164182.2
carboxylesterase 2A
chr14_+_70554056 0.99 ENSMUST00000022691.7
hairless
chr11_+_84525647 0.97 ENSMUST00000134800.1
RIKEN cDNA 1500016L03 gene
chrX_+_136666375 0.96 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
transcription elongation factor A (SII)-like 3
chr9_-_111690313 0.95 ENSMUST00000035083.7
src homology three (SH3) and cysteine rich domain
chr11_-_12026732 0.94 ENSMUST00000143915.1
growth factor receptor bound protein 10
chr7_+_121865070 0.93 ENSMUST00000033161.5
sodium channel, nonvoltage-gated 1 beta
chr3_+_92215835 0.93 ENSMUST00000074449.5
ENSMUST00000090871.2
small proline-rich protein 2A1
small proline-rich protein 2A2
chr7_+_30776394 0.92 ENSMUST00000041703.7
dermokine
chr5_+_135670027 0.91 ENSMUST00000153500.1
P450 (cytochrome) oxidoreductase
chr7_-_46179929 0.88 ENSMUST00000033123.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr5_-_114658414 0.87 ENSMUST00000112225.1
ENSMUST00000071968.2
transient receptor potential cation channel, subfamily V, member 4
chr5_+_137981512 0.85 ENSMUST00000035390.5
alpha-2-glycoprotein 1, zinc
chr13_-_19307551 0.85 ENSMUST00000103561.1
T-cell receptor gamma, constant 2
chr9_-_44454757 0.82 ENSMUST00000047740.2
uroplakin 2
chr10_+_75943020 0.81 ENSMUST00000121151.1
pre-B lymphocyte gene 3
chr19_+_24673998 0.81 ENSMUST00000057243.4
transmembrane protein 252
chr7_+_117380937 0.81 ENSMUST00000032892.5
xylosyltransferase 1
chr6_+_17065129 0.80 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
testis derived transcript
chr3_+_92250647 0.80 ENSMUST00000071805.2
small proline-rich protein 2A2
chr14_+_70553687 0.78 ENSMUST00000161069.1
hairless
chr5_-_120777628 0.78 ENSMUST00000044833.8
2'-5' oligoadenylate synthetase 3
chr7_-_142899985 0.78 ENSMUST00000000219.3
tyrosine hydroxylase
chr17_+_28769307 0.77 ENSMUST00000004986.6
mitogen-activated protein kinase 13
chrX_+_170009659 0.77 ENSMUST00000179760.1
predicted gene, 21887
chr12_+_76417598 0.77 ENSMUST00000063977.7
protein phosphatase 1, regulatory subunit 36
chr12_+_104214538 0.77 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr12_-_113422730 0.76 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr6_-_88875035 0.76 ENSMUST00000145944.1
podocalyxin-like 2
chr15_-_58324161 0.71 ENSMUST00000022985.1
kelch-like 38
chr5_+_150952607 0.70 ENSMUST00000078856.6
klotho
chr5_+_139423151 0.70 ENSMUST00000066211.4
G protein-coupled estrogen receptor 1
chr12_-_103958939 0.70 ENSMUST00000122229.1
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr18_+_31609512 0.69 ENSMUST00000164667.1
RIKEN cDNA B930094E09 gene
chr12_-_17324703 0.69 ENSMUST00000020884.9
ENSMUST00000095820.5
ENSMUST00000127185.1
ATPase, H+ transporting, lysosomal V1 subunit C2
chr13_+_19214103 0.69 ENSMUST00000103558.1
T cell receptor gamma, constant 1
chr4_+_136172367 0.68 ENSMUST00000061721.5
E2F transcription factor 2
chr8_-_31918203 0.68 ENSMUST00000073884.4
neuregulin 1
chr11_+_7063423 0.67 ENSMUST00000020706.4
adenylate cyclase 1
chr2_-_32387760 0.67 ENSMUST00000050785.8
lipocalin 2
chr11_-_100414829 0.67 ENSMUST00000066489.6
leprecan-like 4
chr6_-_115251839 0.66 ENSMUST00000032462.6
tissue inhibitor of metalloproteinase 4
chr18_-_24709348 0.65 ENSMUST00000067987.1
predicted gene 9955
chr4_+_47208005 0.64 ENSMUST00000082303.6
ENSMUST00000102917.4
collagen, type XV, alpha 1
chr16_-_56831878 0.64 ENSMUST00000135672.1
transmembrane protein 45a
chr15_+_85205949 0.63 ENSMUST00000057410.7
ENSMUST00000109432.3
fibulin 1
chr19_-_36057340 0.63 ENSMUST00000164639.1
ENSMUST00000166074.1
ENSMUST00000099505.3
5-hydroxytryptamine (serotonin) receptor 7
chr10_+_60106198 0.63 ENSMUST00000121820.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr11_-_120731944 0.62 ENSMUST00000154565.1
ENSMUST00000026148.2
carbonyl reductase 2
chr2_-_180225812 0.62 ENSMUST00000015791.5
laminin, alpha 5
chr2_-_172458596 0.61 ENSMUST00000099060.1
glucosaminyl (N-acetyl) transferase family member 7
chr13_-_70841790 0.60 ENSMUST00000080145.6
ENSMUST00000109694.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
chr4_+_141368116 0.59 ENSMUST00000006380.4
family with sequence similarity 131, member C
chr17_+_29114142 0.57 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
predicted gene 16194
chr16_+_23058250 0.57 ENSMUST00000039492.6
ENSMUST00000023589.8
ENSMUST00000089902.6
kininogen 1
chr1_-_128359610 0.55 ENSMUST00000027601.4
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chrX_-_7967817 0.55 ENSMUST00000033502.7
GATA binding protein 1
chr17_-_35074485 0.54 ENSMUST00000007259.3
lymphocyte antigen 6 complex, locus G6D
chrX_+_170009892 0.54 ENSMUST00000180251.1
predicted gene, 21887
chr4_+_155790439 0.53 ENSMUST00000165000.1
ankyrin repeat domain 65
chr1_-_144249134 0.53 ENSMUST00000172388.1
regulator of G-protein signaling 1
chr10_-_116473418 0.53 ENSMUST00000087965.4
ENSMUST00000164271.1
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr12_+_84100654 0.52 ENSMUST00000056822.3
acyl-CoA thioesterase 6
chr1_+_88055467 0.52 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr12_-_104865076 0.51 ENSMUST00000109937.1
ENSMUST00000109936.1
calmin
chr15_-_97908261 0.51 ENSMUST00000023119.8
vitamin D receptor
chr19_+_6384395 0.51 ENSMUST00000035269.8
ENSMUST00000113483.1
muscle glycogen phosphorylase
chr4_-_149909719 0.50 ENSMUST00000105685.1
splA/ryanodine receptor domain and SOCS box containing 1
chr11_+_96929367 0.50 ENSMUST00000062172.5
proline rich 15-like
chr10_+_40629987 0.50 ENSMUST00000019977.7
D-aspartate oxidase
chr12_+_104263117 0.50 ENSMUST00000109958.2
serine (or cysteine) peptidase inhibitor, clade A, member 3I
chr9_-_65391652 0.50 ENSMUST00000068307.3
kelch repeat and BTB (POZ) domain containing 13
chrY_+_90784738 0.50 ENSMUST00000179483.1
erythroid differentiation regulator 1
chr7_-_17056669 0.49 ENSMUST00000037762.4
hypoxia inducible factor 3, alpha subunit
chr14_-_120042429 0.49 ENSMUST00000058213.5
oxoglutarate (alpha-ketoglutarate) receptor 1
chr9_-_44526397 0.49 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr1_+_91351016 0.49 ENSMUST00000027533.8
kelch-like 30
chr10_+_80016901 0.48 ENSMUST00000105373.1
histocompatibility (minor) HA-1
chr16_-_23029080 0.47 ENSMUST00000100046.2
kininogen 2
chr2_+_157424255 0.47 ENSMUST00000029175.7
ENSMUST00000092576.4
Rous sarcoma oncogene
chr4_-_126163470 0.47 ENSMUST00000097891.3
SH3 domain containing 21
chr2_-_24475596 0.47 ENSMUST00000028355.4
paired box gene 8
chr7_-_141117772 0.46 ENSMUST00000067836.7
anoctamin 9
chr12_-_80260091 0.46 ENSMUST00000167327.1
actinin, alpha 1
chr17_-_28486082 0.46 ENSMUST00000079413.3
FK506 binding protein 5
chr9_-_119157055 0.46 ENSMUST00000010795.4
acetyl-Coenzyme A acyltransferase 1B
chr16_-_23029012 0.46 ENSMUST00000039338.6
kininogen 2
chr7_+_141455198 0.45 ENSMUST00000164016.1
ENSMUST00000064151.6
ENSMUST00000169665.1
patatin-like phospholipase domain containing 2
chr10_+_127048235 0.45 ENSMUST00000165764.1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr7_+_27119909 0.45 ENSMUST00000003100.8
cytochrome P450, family 2, subfamily f, polypeptide 2
chr7_+_17087934 0.44 ENSMUST00000152671.1
pregnancy specific glycoprotein 16
chr4_-_143299463 0.44 ENSMUST00000119654.1
podoplanin
chr10_+_79879614 0.44 ENSMUST00000006679.8
proteinase 3
chr16_-_23029062 0.44 ENSMUST00000115349.2
kininogen 2
chr14_-_59365410 0.43 ENSMUST00000161031.1
ENSMUST00000160425.1
PHD finger protein 11D
chr19_-_6235804 0.42 ENSMUST00000025695.9
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr1_+_88055377 0.42 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr11_+_58640394 0.42 ENSMUST00000075084.4
tripartite motif-containing 58
chr3_+_94372794 0.42 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr7_-_28291130 0.42 ENSMUST00000108316.2
ENSMUST00000056589.6
cDNA sequence BC089491
chr3_+_19644452 0.41 ENSMUST00000029139.7
tripartite motif-containing 55
chr1_+_153665666 0.41 ENSMUST00000111814.1
ENSMUST00000111810.1
regulator of G-protein signaling 8
chr17_-_45572495 0.41 ENSMUST00000130406.1
heat shock protein 90 alpha (cytosolic), class B member 1
chr2_+_50066429 0.41 ENSMUST00000112712.3
ENSMUST00000128451.1
ENSMUST00000053208.7
LY6/PLAUR domain containing 6
chr16_+_35154870 0.40 ENSMUST00000114913.1
adenylate cyclase 5
chr9_+_90163057 0.40 ENSMUST00000113059.1
ENSMUST00000167122.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr7_+_101818306 0.40 ENSMUST00000008090.9
paired-like homeobox 2a
chr11_+_96929260 0.40 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr5_-_148392810 0.40 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_+_137288273 0.40 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr4_-_111902754 0.40 ENSMUST00000102719.1
ENSMUST00000102721.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr4_-_111898695 0.39 ENSMUST00000102720.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr1_-_170589791 0.39 ENSMUST00000161966.1
ENSMUST00000160456.1
nitric oxide synthase 1 (neuronal) adaptor protein
chr7_-_28547109 0.39 ENSMUST00000057974.3
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr15_-_75567176 0.38 ENSMUST00000156032.1
ENSMUST00000127095.1
lymphocyte antigen 6 complex, locus H
chr17_+_46297917 0.38 ENSMUST00000166617.1
ENSMUST00000170271.1
delta-like 2 homolog (Drosophila)
chr2_-_33640480 0.37 ENSMUST00000176067.1
ENSMUST00000041730.4
LIM homeobox transcription factor 1 beta
chr17_+_32685610 0.37 ENSMUST00000168171.1
cytochrome P450, family 4, subfamily f, polypeptide 15
chr5_+_52363925 0.37 ENSMUST00000101208.4
superoxide dismutase 3, extracellular
chr14_-_59365465 0.37 ENSMUST00000095157.4
PHD finger protein 11D
chr7_+_45434833 0.37 ENSMUST00000003964.8
glycogen synthase 1, muscle
chr2_-_24475097 0.37 ENSMUST00000149294.1
ENSMUST00000153535.1
paired box gene 8
chr5_+_92897981 0.36 ENSMUST00000113051.2
shroom family member 3
chr2_+_93452796 0.35 ENSMUST00000099693.2
ENSMUST00000162565.1
ENSMUST00000163052.1
predicted gene 10804
chr7_+_100472985 0.35 ENSMUST00000032958.7
ENSMUST00000107059.1
uncoupling protein 3 (mitochondrial, proton carrier)
chr3_-_88384433 0.35 ENSMUST00000076048.4
bone gamma carboxyglutamate protein
chr10_+_127000709 0.35 ENSMUST00000026500.5
ENSMUST00000142698.1
advillin
chr11_-_106160708 0.35 ENSMUST00000106875.1
LIM domain containing 2
chr7_-_45666292 0.35 ENSMUST00000069800.4
fucosyltransferase 2
chr13_+_52596847 0.34 ENSMUST00000055087.6
spleen tyrosine kinase
chr10_-_78295394 0.34 ENSMUST00000105387.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_18743691 0.34 ENSMUST00000019999.5
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr10_-_77113676 0.34 ENSMUST00000072755.4
ENSMUST00000105409.1
collagen, type XVIII, alpha 1
chr5_-_41764493 0.34 ENSMUST00000060820.6
NK3 homeobox 2
chr5_+_139543889 0.33 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr2_-_131063508 0.33 ENSMUST00000147333.1
a disintegrin and metallopeptidase domain 33
chr10_+_80016653 0.33 ENSMUST00000099501.3
histocompatibility (minor) HA-1
chr11_-_69805617 0.33 ENSMUST00000051025.4
transmembrane protein 102
chr7_+_82174796 0.33 ENSMUST00000032874.7
SH3-domain GRB2-like 3
chr7_-_19404082 0.33 ENSMUST00000108458.3
kinesin light chain 3
chr11_+_121702591 0.33 ENSMUST00000125580.1
meteorin, glial cell differentiation regulator-like
chr4_+_98546710 0.33 ENSMUST00000102792.3
InaD-like (Drosophila)
chr4_+_106622424 0.33 ENSMUST00000047922.2
tetratricopeptide repeat domain 22
chr12_-_26456423 0.33 ENSMUST00000020970.7
radical S-adenosyl methionine domain containing 2
chr14_+_51091077 0.33 ENSMUST00000022428.5
ENSMUST00000171688.1
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr9_+_51765325 0.32 ENSMUST00000065496.5
Rho GTPase activating protein 20
chr4_-_44072712 0.32 ENSMUST00000102936.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr18_-_61786636 0.32 ENSMUST00000120472.1
actin filament associated protein 1-like 1
chr8_+_95320440 0.32 ENSMUST00000162294.1
testis, prostate and placenta expressed
chr10_+_60106452 0.32 ENSMUST00000165024.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr13_+_119836006 0.32 ENSMUST00000179131.1
DNA segment, Chr 13, ERATO Doi 608, expressed
chr15_+_6422240 0.32 ENSMUST00000163082.1
disabled 2, mitogen-responsive phosphoprotein
chr4_+_98546919 0.31 ENSMUST00000030290.7
InaD-like (Drosophila)
chr19_+_46573362 0.31 ENSMUST00000026011.6
sideroflexin 2
chr2_+_26315513 0.31 ENSMUST00000066936.2
ENSMUST00000078616.5
G-protein signalling modulator 1 (AGS3-like, C. elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.7 2.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.7 3.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.6 1.9 GO:0030221 basophil differentiation(GO:0030221)
0.4 1.3 GO:0051385 response to mineralocorticoid(GO:0051385)
0.4 1.4 GO:0006566 threonine metabolic process(GO:0006566)
0.3 1.0 GO:0042231 interleukin-10 biosynthetic process(GO:0042091) interleukin-13 biosynthetic process(GO:0042231) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 2.0 GO:1902732 antifungal humoral response(GO:0019732) positive regulation of chondrocyte proliferation(GO:1902732)
0.3 1.9 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.3 0.9 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.3 0.9 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 1.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 1.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 1.9 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.3 0.8 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.2 1.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.2 1.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 0.9 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 2.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.9 GO:0090345 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.2 1.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.8 GO:2000612 regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.2 1.4 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.2 1.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 2.5 GO:0006590 thyroid hormone generation(GO:0006590) follicle-stimulating hormone secretion(GO:0046884)
0.2 0.5 GO:0006533 aspartate catabolic process(GO:0006533)
0.2 0.8 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.2 0.8 GO:0042414 epinephrine metabolic process(GO:0042414)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 1.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 1.0 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.4 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.1 0.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.4 GO:1903659 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.4 GO:0021623 trochlear nerve development(GO:0021558) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:0071226 cellular response to molecule of fungal origin(GO:0071226)
0.1 0.5 GO:0042196 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.1 0.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 1.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.6 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 1.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.7 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 0.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.2 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.1 1.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.2 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.9 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 1.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.3 GO:0080144 amino acid homeostasis(GO:0080144)
0.1 1.6 GO:0007614 short-term memory(GO:0007614)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.2 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 1.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 9.5 GO:0015758 glucose transport(GO:0015758)
0.1 0.2 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.8 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.3 GO:0035740 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018) establishment of blood-nerve barrier(GO:0008065)
0.1 0.4 GO:0070317 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:0035026 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 1.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.1 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.0 0.2 GO:0060157 female genitalia morphogenesis(GO:0048807) urinary bladder development(GO:0060157)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.2 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0 4.8 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.6 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 1.9 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.3 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0002606 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
0.0 0.1 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:1900114 dense core granule localization(GO:0032253) positive regulation of histone H3-K9 trimethylation(GO:1900114) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.6 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.9 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.4 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.4 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.2 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392) follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0032280 symmetric synapse(GO:0032280)
0.5 2.0 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.4 1.5 GO:0043259 laminin-10 complex(GO:0043259)
0.3 1.5 GO:1990769 proximal neuron projection(GO:1990769)
0.3 7.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.3 GO:0001652 granular component(GO:0001652)
0.2 0.7 GO:0032127 dense core granule membrane(GO:0032127)
0.2 0.6 GO:0071953 elastic fiber(GO:0071953)
0.2 1.1 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.5 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 0.3 GO:0005940 septin ring(GO:0005940)
0.1 0.6 GO:0071547 piP-body(GO:0071547)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.2 GO:0072534 perineuronal net(GO:0072534)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0034706 sodium channel complex(GO:0034706)
0.0 11.9 GO:0030141 secretory granule(GO:0030141)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 5.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 17.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031673 H zone(GO:0031673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 1.4 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 22.0 GO:0005158 insulin receptor binding(GO:0005158)
0.3 3.4 GO:0035473 lipase binding(GO:0035473)
0.3 0.9 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.3 0.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 1.9 GO:0001515 opioid peptide activity(GO:0001515)
0.3 0.8 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.2 1.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 0.7 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.7 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 0.9 GO:0008941 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.7 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.2 1.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 1.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.5 GO:1902271 lithocholic acid binding(GO:1902121) D3 vitamins binding(GO:1902271)
0.2 0.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.4 GO:0046911 metal chelating activity(GO:0046911)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.6 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 1.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 1.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 18.3 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0008147 structural constituent of bone(GO:0008147)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.4 GO:0002135 CTP binding(GO:0002135)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.1 0.6 GO:0051378 serotonin binding(GO:0051378)
0.1 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0008443 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.7 GO:0019956 chemokine binding(GO:0019956)
0.0 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.6 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.0 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0008940 nitrate reductase activity(GO:0008940)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 1.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 3.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis