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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zkscan1

Z-value: 1.18

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Transcription factors associated with Zkscan1

Gene Symbol Gene ID Gene Info
Zkscan1
ENSMUSG00000029729.6 zinc finger with KRAB and SCAN domains 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.183.0e-01Click!

Activity profile of Zkscan1 motif

Sorted Z-values of Zkscan1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_79881023 5.90 ENSMUST00000166201.1
Prtn3
proteinase 3
chr2_+_84734050 4.60 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chrX_-_49797700 4.06 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1
immunoglobulin superfamily, member 1
chr2_+_153492790 3.79 ENSMUST00000109783.1
4930404H24Rik
RIKEN cDNA 4930404H24 gene
chr15_-_74983430 3.50 ENSMUST00000023250.4
ENSMUST00000166694.1
Ly6i
lymphocyte antigen 6 complex, locus I
chr15_-_75111684 3.40 ENSMUST00000100542.3
Ly6c2
lymphocyte antigen 6 complex, locus C2
chr9_+_51213683 3.15 ENSMUST00000034554.7
Pou2af1
POU domain, class 2, associating factor 1
chr19_-_61228396 3.06 ENSMUST00000076046.6
Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr7_+_24370255 3.04 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr9_-_103480328 2.85 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr2_-_156839790 2.84 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230
predicted gene 14230
chr17_-_33718591 2.82 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
March2
membrane-associated ring finger (C3HC4) 2
chr12_+_109545390 2.77 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr15_-_78572754 2.32 ENSMUST00000043214.6
Rac2
RAS-related C3 botulinum substrate 2
chrX_+_20870166 2.13 ENSMUST00000115342.3
ENSMUST00000009530.4
Timp1
tissue inhibitor of metalloproteinase 1
chr7_-_132813799 2.12 ENSMUST00000097998.2
Fam53b
family with sequence similarity 53, member B
chr2_+_31245801 2.10 ENSMUST00000000199.7
Ncs1
neuronal calcium sensor 1
chr4_-_141078302 1.86 ENSMUST00000030760.8
Necap2
NECAP endocytosis associated 2
chr15_-_75048837 1.84 ENSMUST00000179762.1
ENSMUST00000065408.9
Ly6c1
lymphocyte antigen 6 complex, locus C1
chr12_-_79007276 1.76 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b
transmembrane protein 229B
chr2_+_156840077 1.76 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2
TGFB-induced factor homeobox 2
chr7_-_132813528 1.74 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr6_-_83536215 1.69 ENSMUST00000075161.5
Actg2
actin, gamma 2, smooth muscle, enteric
chr2_+_172393900 1.66 ENSMUST00000109136.2
Cass4
Cas scaffolding protein family member 4
chr15_-_34356421 1.58 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr11_+_31832660 1.57 ENSMUST00000132857.1
Gm12107
predicted gene 12107
chr7_+_29134854 1.52 ENSMUST00000161522.1
ENSMUST00000159975.1
ENSMUST00000032811.5
ENSMUST00000094617.4
Rasgrp4
RAS guanyl releasing protein 4
chr13_+_50417856 1.51 ENSMUST00000046974.4
Fbxw17
F-box and WD-40 domain protein 17
chr4_+_133220810 1.47 ENSMUST00000105910.1
Cd164l2
CD164 sialomucin-like 2
chr12_+_116405397 1.28 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr2_-_127729872 1.26 ENSMUST00000028856.2
Mall
mal, T cell differentiation protein-like
chr15_-_79164477 1.18 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr17_+_34039437 1.17 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2
collagen, type XI, alpha 2
chr11_+_104577281 1.12 ENSMUST00000106956.3
Myl4
myosin, light polypeptide 4
chr5_-_134229581 1.05 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
Ncf1
neutrophil cytosolic factor 1
chr5_-_140321524 1.04 ENSMUST00000031534.6
Mad1l1
MAD1 mitotic arrest deficient 1-like 1
chr10_+_127000709 1.03 ENSMUST00000026500.5
ENSMUST00000142698.1
Avil
advillin
chr7_-_98162318 1.00 ENSMUST00000107112.1
Capn5
calpain 5
chr19_+_12798574 0.98 ENSMUST00000025601.6
Lpxn
leupaxin
chr19_+_10937154 0.95 ENSMUST00000037261.3
Gpr44
G protein-coupled receptor 44
chr6_+_47877204 0.91 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr7_-_132813715 0.90 ENSMUST00000134946.1
Fam53b
family with sequence similarity 53, member B
chr4_+_103619580 0.90 ENSMUST00000106827.1
Dab1
disabled 1
chr18_+_27598582 0.86 ENSMUST00000050143.3
Gm7729
predicted gene 7729
chr4_+_129960760 0.79 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr5_-_131538687 0.75 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr15_+_101411053 0.74 ENSMUST00000147662.1
Krt7
keratin 7
chr8_+_84949860 0.71 ENSMUST00000121880.1
Rtbdn
retbindin
chr19_+_53310495 0.68 ENSMUST00000003870.7
Mxi1
Max interacting protein 1
chr1_+_50927511 0.68 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_+_119052770 0.66 ENSMUST00000051386.6
ENSMUST00000074734.6
Vill
villin-like
chr11_-_47379405 0.66 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr4_-_63495951 0.66 ENSMUST00000063650.3
ENSMUST00000102867.1
ENSMUST00000107393.1
ENSMUST00000084510.1
ENSMUST00000095038.1
ENSMUST00000119294.1
ENSMUST00000095037.1
ENSMUST00000063672.3
Whrn
whirlin
chr6_-_145047725 0.64 ENSMUST00000123930.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr6_-_122340525 0.62 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr12_-_76818374 0.60 ENSMUST00000118604.1
Rab15
RAB15, member RAS oncogene family
chr6_-_99726392 0.60 ENSMUST00000032152.8
ENSMUST00000101120.4
ENSMUST00000008273.6
Prok2
prokineticin 2
chr9_+_119052863 0.59 ENSMUST00000131647.1
Vill
villin-like
chrX_+_164373363 0.59 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr17_+_24886643 0.58 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3
splA/ryanodine receptor domain and SOCS box containing 3
chr18_-_6490808 0.56 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr19_+_10525244 0.54 ENSMUST00000038379.3
Cpsf7
cleavage and polyadenylation specific factor 7
chr17_+_75005523 0.49 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr4_+_45890303 0.48 ENSMUST00000178561.1
E230008N13Rik
RIKEN cDNA E230008N13 gene
chr6_-_122340499 0.46 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr1_+_171840607 0.45 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84
CD84 antigen
chr18_-_52529847 0.44 ENSMUST00000171470.1
Lox
lysyl oxidase
chr16_+_17489600 0.44 ENSMUST00000115685.1
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr2_-_105399286 0.44 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr2_+_172393794 0.44 ENSMUST00000099061.2
ENSMUST00000103073.2
Cass4
Cas scaffolding protein family member 4
chr6_-_145047636 0.42 ENSMUST00000149769.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr2_+_90677208 0.41 ENSMUST00000057481.6
Nup160
nucleoporin 160
chr12_+_53248677 0.41 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr9_+_106368594 0.40 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr7_-_118491912 0.39 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr7_+_144896523 0.38 ENSMUST00000033389.5
Fgf15
fibroblast growth factor 15
chr10_-_39122277 0.35 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr4_+_109406623 0.35 ENSMUST00000124209.1
Ttc39a
tetratricopeptide repeat domain 39A
chr16_+_17489639 0.34 ENSMUST00000023448.6
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr8_-_70527945 0.34 ENSMUST00000138260.1
ENSMUST00000117580.1
Kxd1
KxDL motif containing 1
chr11_+_78826575 0.32 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9
LYR motif containing 9
chr11_-_61453992 0.32 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
Rnf112
ring finger protein 112
chr5_-_8367982 0.32 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22
a disintegrin and metallopeptidase domain 22
chr18_+_61105844 0.30 ENSMUST00000115268.3
Csf1r
colony stimulating factor 1 receptor
chr4_+_42922253 0.30 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr4_+_141444654 0.29 ENSMUST00000006377.6
Zbtb17
zinc finger and BTB domain containing 17
chr15_+_85017138 0.29 ENSMUST00000023070.5
Upk3a
uroplakin 3A
chr1_+_171840557 0.27 ENSMUST00000135386.1
Cd84
CD84 antigen
chr2_+_172472512 0.26 ENSMUST00000029007.2
Fam209
family with sequence similarity 209
chr5_+_31116722 0.24 ENSMUST00000114637.1
Trim54
tripartite motif-containing 54
chr5_+_31116702 0.23 ENSMUST00000013771.8
Trim54
tripartite motif-containing 54
chr19_+_43689672 0.23 ENSMUST00000081079.5
Entpd7
ectonucleoside triphosphate diphosphohydrolase 7
chr11_+_69981127 0.23 ENSMUST00000108593.1
Ctdnep1
CTD nuclear envelope phosphatase 1
chr15_+_16778101 0.22 ENSMUST00000026432.6
Cdh9
cadherin 9
chr11_-_69981242 0.22 ENSMUST00000108594.1
Elp5
elongator acetyltransferase complex subunit 5
chr4_-_116144609 0.21 ENSMUST00000030469.4
Lurap1
leucine rich adaptor protein 1
chr11_-_78512105 0.21 ENSMUST00000052566.7
Tmem199
transmembrane protein 199
chr3_-_88378699 0.19 ENSMUST00000098956.2
Bglap2
bone gamma-carboxyglutamate protein 2
chr8_-_70527645 0.18 ENSMUST00000132867.1
Kxd1
KxDL motif containing 1
chr1_-_93635692 0.18 ENSMUST00000027498.7
Stk25
serine/threonine kinase 25 (yeast)
chr15_+_83779999 0.17 ENSMUST00000046168.5
Mpped1
metallophosphoesterase domain containing 1
chr18_+_31609512 0.15 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr1_-_93635479 0.14 ENSMUST00000133769.1
Stk25
serine/threonine kinase 25 (yeast)
chr8_+_72646679 0.14 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1
NACHT and WD repeat domain containing 1
chr8_+_4253067 0.14 ENSMUST00000011981.3
Snapc2
small nuclear RNA activating complex, polypeptide 2
chr16_-_10447340 0.13 ENSMUST00000051118.6
Tvp23a
trans-golgi network vesicle protein 23A
chr2_-_73580288 0.12 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr19_+_5088534 0.12 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr12_-_111574384 0.12 ENSMUST00000180698.1
2810029C07Rik
RIKEN cDNA 2810029C07 gene
chrX_+_159372175 0.12 ENSMUST00000087143.6
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
chr7_-_28962265 0.12 ENSMUST00000068045.7
Actn4
actinin alpha 4
chr18_+_14424821 0.11 ENSMUST00000069552.5
Gm5160
predicted gene 5160
chr2_+_118900377 0.09 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr4_+_101419277 0.08 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4
adenylate kinase 4
chr14_-_52316323 0.05 ENSMUST00000135523.1
Sall2
sal-like 2 (Drosophila)
chr9_+_98422961 0.04 ENSMUST00000052068.9
Rbp1
retinol binding protein 1, cellular
chr7_-_28962223 0.04 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr11_+_120458093 0.04 ENSMUST00000058370.7
ENSMUST00000175970.1
ENSMUST00000176120.1
Ccdc137
coiled-coil domain containing 137
chr3_+_89136133 0.04 ENSMUST00000047111.6
Pklr
pyruvate kinase liver and red blood cell
chr4_-_47057296 0.03 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6
ankyrin repeat and sterile alpha motif domain containing 6
chr4_-_133277730 0.03 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr4_-_97584612 0.03 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr10_-_79555077 0.02 ENSMUST00000170018.1
ENSMUST00000062855.8
ENSMUST00000165778.1
ENSMUST00000165028.1
Mier2
mesoderm induction early response 1, family member 2
chr11_+_78512193 0.02 ENSMUST00000001127.4
Poldip2
polymerase (DNA-directed), delta interacting protein 2
chr3_+_96645579 0.00 ENSMUST00000119365.1
ENSMUST00000029744.5
Itga10
integrin, alpha 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.4 1.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.3 0.9 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 2.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 2.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 1.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.7 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 2.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 0.6 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.2 1.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 1.2 GO:0060023 soft palate development(GO:0060023)
0.2 1.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 2.9 GO:0070307 lens fiber cell development(GO:0070307)
0.2 1.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 2.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.1 0.4 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 1.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.7 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 2.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 4.8 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 1.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.0 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 1.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 2.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0015840 urea transport(GO:0015840)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 2.1 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.4 GO:0042711 maternal behavior(GO:0042711)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.5 GO:0032418 lysosome localization(GO:0032418)
0.0 0.8 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 0.7 GO:1990696 USH2 complex(GO:1990696)
0.2 0.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 1.3 GO:0000796 condensin complex(GO:0000796)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.1 GO:0031045 dense core granule(GO:0031045)
0.1 1.1 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 8.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 3.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0031672 A band(GO:0031672)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 1.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.5 4.1 GO:0034711 inhibin binding(GO:0034711)
0.2 1.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 2.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 3.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.2 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.4 GO:0019955 cytokine binding(GO:0019955)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 7.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 3.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.2 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase