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GSE58827: Dynamics of the Mouse Liver
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Results for Arid5a
Z-value: 0.51
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Transcription factors associated with Arid5a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Arid5a | mm39_v1_chr1_+_36346824_36346850 | -0.73 | 3.9e-07 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_-_87074380 Show fit | 6.03 |
ENSMUST00000031183.3
|
UDP glucuronosyltransferase 2 family, polypeptide B1 |
|
| chr2_+_58645189 Show fit | 5.72 |
ENSMUST00000102755.4
ENSMUST00000230627.2 ENSMUST00000229923.2 |
uridine phosphorylase 2 |
|
| chr2_+_58644922 Show fit | 5.09 |
ENSMUST00000059102.13
|
uridine phosphorylase 2 |
|
| chr10_-_115198093 Show fit | 3.82 |
ENSMUST00000219890.2
ENSMUST00000218731.2 ENSMUST00000217887.2 ENSMUST00000092170.7 |
transmembrane protein 19 |
|
| chr7_-_105249308 Show fit | 3.16 |
ENSMUST00000210531.2
ENSMUST00000033185.10 |
hemopexin |
|
| chr10_-_115197775 Show fit | 2.95 |
ENSMUST00000217848.2
|
transmembrane protein 19 |
|
| chr15_-_55421144 Show fit | 1.02 |
ENSMUST00000172387.8
|
mitochondrial ribosomal protein L13 |
|
| chr14_+_58313964 Show fit | 0.73 |
ENSMUST00000166770.2
|
fibroblast growth factor 9 |
|
| chr3_+_122298308 Show fit | 0.65 |
ENSMUST00000199358.2
|
breast cancer anti-estrogen resistance 3 |
|
| chr1_-_171885140 Show fit | 0.62 |
ENSMUST00000059794.4
|
nescient helix loop helix 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Arid5a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.9 | GO:0009166 | nucleotide catabolic process(GO:0009166) |
| 2.0 | 6.0 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
| 0.5 | 3.2 | GO:0060335 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.0 | 0.7 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 0.7 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.7 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.6 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.0 | 0.6 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.1 | 0.5 | GO:1904937 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
| 0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 10.8 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.0 | 1.0 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.7 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 0.6 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.0 | 0.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 10.8 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.1 | 6.0 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.5 | 3.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.6 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 0.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.5 | GO:0003680 | AT DNA binding(GO:0003680) co-SMAD binding(GO:0070410) |
| 0.0 | 0.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 10.8 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 0.7 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 0.6 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |