Project
GSE58827: Dynamics of the Mouse Liver
Navigation
Downloads
Results for Zbtb18
Z-value: 1.44
Motif logo
Transcription factors associated with Zbtb18
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb18 | mm39_v1_chr1_+_177273226_177273387 | -0.31 | 6.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_112417633 Show fit | 25.34 |
ENSMUST00000034435.7
|
chymotrypsinogen B1 |
|
| chr8_-_106660470 Show fit | 15.53 |
ENSMUST00000034368.8
|
chymotrypsin-like |
|
| chr14_+_30608433 Show fit | 10.23 |
ENSMUST00000120269.11
ENSMUST00000078490.14 ENSMUST00000006703.15 |
inter alpha-trypsin inhibitor, heavy chain 4 |
|
| chr14_+_30608478 Show fit | 10.11 |
ENSMUST00000168782.4
|
inter alpha-trypsin inhibitor, heavy chain 4 |
|
| chr6_-_41012435 Show fit | 10.08 |
ENSMUST00000031931.6
|
RIKEN cDNA 2210010C04 gene |
|
| chr4_-_115353326 Show fit | 9.81 |
ENSMUST00000030487.3
|
cytochrome P450, family 4, subfamily a, polypeptide 14 |
|
| chr17_-_28779678 Show fit | 8.48 |
ENSMUST00000114785.3
ENSMUST00000025062.5 |
colipase, pancreatic |
|
| chr17_-_12894716 Show fit | 8.48 |
ENSMUST00000024596.10
|
solute carrier family 22 (organic cation transporter), member 1 |
|
| chr17_-_84990360 Show fit | 8.36 |
ENSMUST00000066175.10
|
ATP binding cassette subfamily G member 5 |
|
| chr12_-_103956176 Show fit | 6.88 |
ENSMUST00000151709.3
ENSMUST00000176246.3 ENSMUST00000074693.13 ENSMUST00000120251.9 |
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zbtb18
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 33.8 | GO:0007586 | digestion(GO:0007586) |
| 0.3 | 16.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 2.3 | 13.8 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 3.9 | 11.8 | GO:0009087 | methionine catabolic process(GO:0009087) |
| 0.0 | 10.8 | GO:0055114 | oxidation-reduction process(GO:0055114) |
| 1.3 | 10.1 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 1.3 | 8.9 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 2.9 | 8.7 | GO:0031104 | dendrite regeneration(GO:0031104) |
| 2.8 | 8.4 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 1.3 | 7.5 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 32.1 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 30.3 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 19.1 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 18.6 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.9 | 13.8 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
| 0.0 | 12.6 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 11.2 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 10.9 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 10.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 1.0 | 9.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 60.5 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.2 | 22.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 2.8 | 19.3 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 0.7 | 18.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.5 | 13.8 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 3.0 | 11.8 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 1.4 | 11.4 | GO:0050649 | testosterone 6-beta-hydroxylase activity(GO:0050649) |
| 2.3 | 9.3 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 0.7 | 8.9 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 2.8 | 8.5 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 30.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 11.7 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.6 | 9.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 9.3 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.2 | 7.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 5.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 5.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 5.0 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 4.6 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 3.2 | PID BCR 5PATHWAY | BCR signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 23.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 1.0 | 14.2 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.6 | 13.8 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.3 | 11.1 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.4 | 9.8 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.5 | 9.3 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.4 | 8.9 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.6 | 8.5 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 8.5 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.5 | 7.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |