ISMARA results: Zkscan3

Project

GSE58827: Dynamics of the Mouse Liver

Navigation

Downloads

Results for Zkscan3

Z-value: 0.94

Motif logo

Transcription factors associated with Zkscan3

Gene Symbol	Gene ID	Gene Info
Zkscan3 Ensembl NCBI MGI UniProt	ENSMUSG00000021327.20	zinc finger with KRAB and SCAN domains 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zkscan3	mm39_v1_chr13_-_21586858_21586925	0.39	1.7e-02	Click!

Activity profile of Zkscan3 motif

Sorted Z-values of Zkscan3 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_-_112417633 Show fit	18.56	ENSMUST00000034435.7	Ctrb1 Ensembl NCBI MGI UniProt Show fit	chymotrypsinogen B1
chr11_-_102255999 Show fit	11.52	ENSMUST00000006749.10	Slc4a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 4 (anion exchanger), member 1
chr13_-_100922910 Show fit	7.78	ENSMUST00000174038.2 ENSMUST00000091295.14 ENSMUST00000072119.15	Ccnb1 Ensembl NCBI MGI UniProt Show fit	cyclin B1
chr10_+_75404482 Show fit	7.36	ENSMUST00000134503.8 ENSMUST00000125770.8 ENSMUST00000128886.8 ENSMUST00000151212.8	Ggt1 Ensembl NCBI MGI UniProt Show fit	gamma-glutamyltransferase 1
chr13_+_73615316 Show fit	5.94	ENSMUST00000022099.15	Lpcat1 Ensembl NCBI MGI UniProt Show fit	lysophosphatidylcholine acyltransferase 1
chr5_-_100720063 Show fit	5.77	ENSMUST00000031264.12	Plac8 Ensembl NCBI MGI UniProt Show fit	placenta-specific 8
chr10_+_75404464 Show fit	4.87	ENSMUST00000145928.8 ENSMUST00000131565.8	Ggt1 Ensembl NCBI MGI UniProt Show fit	gamma-glutamyltransferase 1
chr6_+_125529911 Show fit	4.73	ENSMUST00000112254.8 ENSMUST00000112253.6	Vwf Ensembl NCBI MGI UniProt Show fit	Von Willebrand factor
chr11_+_115790768 Show fit	4.02	ENSMUST00000152171.8	Smim5 Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 5
chr7_-_97827461 Show fit	3.55	ENSMUST00000040971.14	Capn5 Ensembl NCBI MGI UniProt Show fit	calpain 5

Showing 1 to 10 of 79 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan3

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	16.9	GO:0007586	digestion(GO:0007586)
1.5	12.2	GO:0031179	peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4	11.5	GO:0015701	bicarbonate transport(GO:0015701)
1.9	7.8	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
1.5	5.9	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2	5.8	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	4.7	GO:0030168	platelet activation(GO:0030168)
0.4	3.4	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.5	3.3	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0	2.7	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)

Showing 1 to 10 of 46 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	17.7	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	11.9	GO:0014704	intercalated disc(GO:0014704)
1.9	7.8	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	6.0	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	5.6	GO:0005811	lipid particle(GO:0005811)
0.5	4.7	GO:0033093	Weibel-Palade body(GO:0033093)
0.8	3.3	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.1	3.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	2.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.7	2.1	GO:0034455	t-UTP complex(GO:0034455)

Showing 1 to 10 of 27 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	19.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.0	12.2	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.5	11.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
1.3	7.8	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.0	5.9	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2	4.7	GO:0019865	immunoglobulin binding(GO:0019865)
0.1	3.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.1	3.3	GO:0005011	macrophage colony-stimulating factor receptor activity(GO:0005011)
0.9	2.7	GO:0004373	glycogen (starch) synthase activity(GO:0004373)
0.2	2.5	GO:0019957	C-C chemokine binding(GO:0019957)

Showing 1 to 10 of 31 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.8	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	6.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	2.9	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	1.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.9	PID FOXO PATHWAY	FoxO family signaling
0.0	0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Showing 1 to 8 of 8 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	17.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.2	12.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	11.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6	7.8	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3	5.9	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.3	4.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	2.7	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.3	2.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	2.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.1	2.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Showing 1 to 10 of 23 entries

Results for Zkscan3

Z-value: 0.94

Motif logo

Transcription factors associated with Zkscan3

Activity-expression correlation:

Activity profile of Zkscan3 motif

Sorted Z-values of Zkscan3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan3

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: