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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for AAUCUCA

Z-value: 0.14

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miRNA associated with seed AAUCUCA

NamemiRBASE accession
hsa-miR-216a-5p
MIMAT0000273

Activity profile of AAUCUCA motif

Sorted Z-values of AAUCUCA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_25352116 0.43 ENST00000584787.5
ENST00000538137.6
ENST00000361524.8
ZNF521
zinc finger protein 521
chr7_+_12211259 0.22 ENST00000396668.8
ENST00000444443.5
ENST00000396667.7
TMEM106B
transmembrane protein 106B
chr11_+_74748831 0.22 ENST00000299563.5
RNF169
ring finger protein 169
chr9_-_20622479 0.16 ENST00000380338.9
MLLT3
MLLT3 super elongation complex subunit
chr18_+_62325294 0.15 ENST00000586569.3
TNFRSF11A
TNF receptor superfamily member 11a
chrX_-_20266834 0.14 ENST00000379565.9
RPS6KA3
ribosomal protein S6 kinase A3
chr1_-_53328053 0.11 ENST00000371454.6
ENST00000667377.1
ENST00000306052.12
ENST00000668448.1
LRP8
LDL receptor related protein 8
chr17_-_75979117 0.10 ENST00000301608.8
ENST00000293217.10
ENST00000588176.5
ACOX1
acyl-CoA oxidase 1
chr6_+_42782020 0.10 ENST00000314073.9
BICRAL
BRD4 interacting chromatin remodeling complex associated protein like
chr6_-_44297672 0.07 ENST00000371505.5
TCTE1
t-complex-associated-testis-expressed 1
chr4_+_98995709 0.07 ENST00000296411.11
ENST00000625963.1
METAP1
methionyl aminopeptidase 1
chr18_+_62187247 0.06 ENST00000644646.2
ENST00000256858.10
ENST00000398130.6
RELCH
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
chr5_+_123089223 0.05 ENST00000407847.5
PRDM6
PR/SET domain 6
chr13_-_30464234 0.05 ENST00000399489.5
ENST00000339872.8
HMGB1
high mobility group box 1
chr5_-_178627001 0.03 ENST00000611575.4
ENST00000520957.1
ENST00000316308.9
ENST00000611733.4
CLK4
CDC like kinase 4
chr17_+_32350132 0.03 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
ZNF207
zinc finger protein 207
chr5_+_149730260 0.02 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARGC1B
PPARG coactivator 1 beta
chr17_+_55264952 0.02 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr1_-_67430412 0.01 ENST00000370994.8
SERBP1
SERPINE1 mRNA binding protein 1
chr13_-_45341086 0.01 ENST00000309246.9
ENST00000379060.8
ENST00000379055.5
ENST00000527226.2
ENST00000530705.6
ENST00000379056.5
ENST00000616577.4
TPT1
tumor protein, translationally-controlled 1
chr1_-_67054100 0.01 ENST00000235345.6
SLC35D1
solute carrier family 35 member D1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071848 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)