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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for AIRE

Z-value: 0.60

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Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
AIRE
ENSG00000160224.17 AIRE

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AIREhg38_v1_chr21_+_44285869_44285884-0.413.9e-02Click!

Activity profile of AIRE motif

Sorted Z-values of AIRE motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_224947030 2.56 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr12_+_75480800 2.29 ENST00000456650.7
GLIPR1
GLI pathogenesis related 1
chr12_+_75481204 2.10 ENST00000550491.1
GLIPR1
GLI pathogenesis related 1
chr1_-_169734064 1.96 ENST00000333360.12
SELE
selectin E
chr1_+_165895583 1.55 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr8_+_53851786 1.27 ENST00000297313.8
ENST00000344277.10
RGS20
regulator of G protein signaling 20
chr8_+_103372388 1.27 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr5_+_119354771 1.26 ENST00000503646.1
TNFAIP8
TNF alpha induced protein 8
chr19_-_10380558 1.18 ENST00000524462.5
ENST00000525621.6
ENST00000531836.5
TYK2
tyrosine kinase 2
chr17_+_79034185 1.11 ENST00000581774.5
C1QTNF1
C1q and TNF related 1
chr11_+_35189964 0.99 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr1_+_78649818 0.97 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr12_+_75480745 0.94 ENST00000266659.8
GLIPR1
GLI pathogenesis related 1
chr20_+_59628609 0.89 ENST00000541461.5
PHACTR3
phosphatase and actin regulator 3
chr1_-_154627906 0.82 ENST00000679899.1
ADAR
adenosine deaminase RNA specific
chr8_+_103298433 0.77 ENST00000522566.5
FZD6
frizzled class receptor 6
chr2_-_37671633 0.73 ENST00000295324.4
CDC42EP3
CDC42 effector protein 3
chr10_+_89283685 0.72 ENST00000638108.1
IFIT2
interferon induced protein with tetratricopeptide repeats 2
chrM_+_12329 0.71 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr1_-_154627945 0.64 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
ADAR
adenosine deaminase RNA specific
chr1_-_154627576 0.58 ENST00000648311.1
ADAR
adenosine deaminase RNA specific
chr10_+_112374110 0.58 ENST00000354655.9
ACSL5
acyl-CoA synthetase long chain family member 5
chr8_+_123768431 0.47 ENST00000334705.12
ENST00000521166.5
FAM91A1
family with sequence similarity 91 member A1
chr1_+_15153698 0.46 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
TMEM51
transmembrane protein 51
chr1_-_243163310 0.46 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
CEP170
centrosomal protein 170
chrX_+_154144242 0.45 ENST00000369951.9
OPN1LW
opsin 1, long wave sensitive
chr3_-_139480723 0.45 ENST00000511956.1
ENST00000506825.1
RBP2
retinol binding protein 2
chrY_-_23694579 0.43 ENST00000343584.10
PRYP3
PTPN13 like Y-linked pseudogene 3
chr19_-_51028015 0.40 ENST00000319720.11
KLK11
kallikrein related peptidase 11
chr2_-_189179754 0.40 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr7_-_36724380 0.39 ENST00000617267.4
AOAH
acyloxyacyl hydrolase
chr4_+_94489030 0.38 ENST00000510099.5
PDLIM5
PDZ and LIM domain 5
chr14_-_81436447 0.37 ENST00000649389.1
ENST00000557055.5
STON2
stonin 2
chr19_-_46746421 0.37 ENST00000263280.11
STRN4
striatin 4
chr1_-_149861210 0.37 ENST00000579512.2
H4C15
H4 clustered histone 15
chr7_-_36724457 0.35 ENST00000617537.5
ENST00000435386.1
AOAH
acyloxyacyl hydrolase
chr20_+_8789517 0.35 ENST00000437439.2
PLCB1
phospholipase C beta 1
chr17_-_41178219 0.34 ENST00000377726.3
KRTAP4-2
keratin associated protein 4-2
chr3_+_46370854 0.33 ENST00000292303.4
CCR5
C-C motif chemokine receptor 5
chr12_-_101830926 0.32 ENST00000299314.12
GNPTAB
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr11_-_8932944 0.32 ENST00000326053.10
ENST00000525780.5
C11orf16
chromosome 11 open reading frame 16
chr6_+_26538338 0.32 ENST00000377575.3
HMGN4
high mobility group nucleosomal binding domain 4
chr7_-_36724543 0.31 ENST00000612871.4
AOAH
acyloxyacyl hydrolase
chrM_+_5824 0.31 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr16_+_50025217 0.30 ENST00000427478.7
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr12_-_62192762 0.30 ENST00000416284.8
TAFA2
TAFA chemokine like family member 2
chr17_-_40565459 0.30 ENST00000578085.1
ENST00000246657.2
CCR7
C-C motif chemokine receptor 7
chr2_-_165204042 0.29 ENST00000283254.12
ENST00000453007.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr17_-_3398410 0.28 ENST00000322608.2
OR1E1
olfactory receptor family 1 subfamily E member 1
chr8_-_15238423 0.27 ENST00000382080.6
SGCZ
sarcoglycan zeta
chr16_-_89418292 0.27 ENST00000683497.1
ENST00000642443.1
ENST00000644784.1
ENST00000647238.1
ENSG00000288715.1
ANKRD11
novel protein
ankyrin repeat domain 11
chr19_+_55857437 0.27 ENST00000587891.5
NLRP4
NLR family pyrin domain containing 4
chr11_-_5324297 0.27 ENST00000624187.1
OR51B2
olfactory receptor family 51 subfamily B member 2
chr17_+_43780425 0.26 ENST00000449302.8
CFAP97D1
CFAP97 domain containing 1
chr4_-_119322128 0.26 ENST00000274024.4
FABP2
fatty acid binding protein 2
chrX_-_49184789 0.26 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr17_+_7306975 0.26 ENST00000336452.11
EIF5A
eukaryotic translation initiation factor 5A
chr9_-_65285209 0.25 ENST00000377420.1
FOXD4L5
forkhead box D4 like 5
chr2_-_222656067 0.25 ENST00000281828.8
FARSB
phenylalanyl-tRNA synthetase subunit beta
chr22_+_24806265 0.24 ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr3_-_48089203 0.24 ENST00000468075.2
ENST00000360240.10
MAP4
microtubule associated protein 4
chr14_-_64942720 0.24 ENST00000557049.1
ENST00000389614.6
GPX2
glutathione peroxidase 2
chr19_-_16496156 0.23 ENST00000269881.8
CALR3
calreticulin 3
chr5_+_122845584 0.21 ENST00000395451.8
ENST00000261369.9
ENST00000506996.5
SNX24
sorting nexin 24
chr12_-_6470643 0.21 ENST00000535180.5
ENST00000400911.7
VAMP1
vesicle associated membrane protein 1
chr6_+_131637296 0.21 ENST00000358229.6
ENST00000357639.8
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_+_162497805 0.21 ENST00000538489.5
ENST00000489294.2
UHMK1
U2AF homology motif kinase 1
chr4_+_15339818 0.20 ENST00000397700.6
ENST00000295297.4
C1QTNF7
C1q and TNF related 7
chr2_+_119679184 0.20 ENST00000445518.1
ENST00000272521.7
ENST00000409951.1
TMEM177
transmembrane protein 177
chr12_-_6470667 0.20 ENST00000361716.8
ENST00000396308.4
VAMP1
vesicle associated membrane protein 1
chr8_-_24956604 0.20 ENST00000610854.2
NEFL
neurofilament light
chr4_-_174829212 0.20 ENST00000340217.5
ENST00000274093.8
GLRA3
glycine receptor alpha 3
chr21_-_6467509 0.20 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
CBSL
cystathionine beta-synthase like
chr1_+_207496268 0.18 ENST00000529814.1
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr1_-_161238196 0.18 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
NR1I3
nuclear receptor subfamily 1 group I member 3
chr15_+_22094522 0.17 ENST00000328795.5
OR4N4
olfactory receptor family 4 subfamily N member 4
chr8_+_127736046 0.17 ENST00000641036.1
ENST00000377970.6
MYC
MYC proto-oncogene, bHLH transcription factor
chr14_-_24442765 0.17 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr5_+_122845488 0.17 ENST00000513881.5
SNX24
sorting nexin 24
chr6_-_39322968 0.17 ENST00000507712.5
KCNK16
potassium two pore domain channel subfamily K member 16
chr1_+_47137435 0.17 ENST00000371891.8
ENST00000371890.7
ENST00000619754.4
ENST00000294337.7
ENST00000620131.1
CYP4A22
cytochrome P450 family 4 subfamily A member 22
chr14_-_100569780 0.16 ENST00000355173.7
BEGAIN
brain enriched guanylate kinase associated
chr2_+_29113989 0.15 ENST00000404424.5
CLIP4
CAP-Gly domain containing linker protein family member 4
chr10_-_100081854 0.15 ENST00000370418.8
CPN1
carboxypeptidase N subunit 1
chr9_-_21482313 0.15 ENST00000448696.4
IFNE
interferon epsilon
chr4_-_75724362 0.15 ENST00000677583.1
G3BP2
G3BP stress granule assembly factor 2
chr3_-_33645433 0.15 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chr13_-_46182136 0.14 ENST00000323076.7
LCP1
lymphocyte cytosolic protein 1
chr6_-_11044275 0.14 ENST00000354666.4
ELOVL2
ELOVL fatty acid elongase 2
chr9_-_101435760 0.14 ENST00000647789.2
ENST00000616752.1
ALDOB
aldolase, fructose-bisphosphate B
chr6_+_10694916 0.14 ENST00000379568.4
PAK1IP1
PAK1 interacting protein 1
chr12_-_10986912 0.14 ENST00000506868.1
TAS2R50
taste 2 receptor member 50
chr2_+_233778330 0.14 ENST00000389758.3
MROH2A
maestro heat like repeat family member 2A
chr6_+_42173358 0.14 ENST00000372958.2
GUCA1A
guanylate cyclase activator 1A
chr7_-_66995576 0.14 ENST00000246868.7
ENST00000617799.1
SBDS
SBDS ribosome maturation factor
chr4_-_146945873 0.13 ENST00000502319.1
ENST00000504425.5
TTC29
tetratricopeptide repeat domain 29
chrX_-_101052087 0.13 ENST00000372936.4
ENST00000545398.5
TRMT2B
tRNA methyltransferase 2 homolog B
chr3_-_88149815 0.13 ENST00000467332.1
ENST00000462901.5
CGGBP1
CGG triplet repeat binding protein 1
chr8_+_104339796 0.13 ENST00000622554.1
ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr15_+_21651844 0.13 ENST00000623441.1
OR4N4C
olfactory receptor family 4 subfamily N member 4C
chrX_-_101052054 0.13 ENST00000372939.5
ENST00000372935.5
TRMT2B
tRNA methyltransferase 2 homolog B
chr19_-_51027954 0.13 ENST00000391804.7
KLK11
kallikrein related peptidase 11
chr14_-_24442662 0.12 ENST00000554698.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr1_+_100345018 0.12 ENST00000635056.2
ENST00000647005.1
CDC14A
cell division cycle 14A
chr21_+_38272291 0.12 ENST00000438657.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr7_+_149872955 0.11 ENST00000421974.7
ENST00000456496.7
ATP6V0E2
ATPase H+ transporting V0 subunit e2
chr7_+_150801695 0.11 ENST00000475536.5
ENST00000468689.2
TMEM176A
transmembrane protein 176A
chr13_-_26221703 0.11 ENST00000381570.7
ENST00000346166.7
RNF6
ring finger protein 6
chr12_-_11310420 0.11 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
PRB4
proline rich protein BstNI subfamily 4
chr14_-_55191534 0.11 ENST00000395425.6
ENST00000247191.7
DLGAP5
DLG associated protein 5
chr6_+_36871841 0.11 ENST00000359359.6
C6orf89
chromosome 6 open reading frame 89
chr16_-_31135699 0.10 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
PRSS8
serine protease 8
chr1_-_11796536 0.10 ENST00000641820.1
MTHFR
methylenetetrahydrofolate reductase
chr4_-_146945807 0.10 ENST00000513335.5
TTC29
tetratricopeptide repeat domain 29
chr1_+_241652275 0.10 ENST00000366552.6
ENST00000437684.7
WDR64
WD repeat domain 64
chr8_+_90940517 0.10 ENST00000521366.1
NECAB1
N-terminal EF-hand calcium binding protein 1
chr4_-_146945841 0.10 ENST00000325106.9
TTC29
tetratricopeptide repeat domain 29
chr3_+_88149947 0.10 ENST00000318887.8
ENST00000486971.1
C3orf38
chromosome 3 open reading frame 38
chr6_-_39322688 0.09 ENST00000437525.3
KCNK16
potassium two pore domain channel subfamily K member 16
chr14_+_22112280 0.09 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chrX_-_103686687 0.09 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
MORF4L2
mortality factor 4 like 2
chrX_+_71283577 0.09 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
NONO
non-POU domain containing octamer binding
chr6_-_131628165 0.09 ENST00000368053.8
ENST00000354577.8
ENST00000368060.7
ENST00000368068.8
MED23
mediator complex subunit 23
chr19_-_35228699 0.09 ENST00000324675.3
FAM187B
family with sequence similarity 187 member B
chr19_+_11345223 0.09 ENST00000588790.5
CCDC159
coiled-coil domain containing 159
chr12_-_11269696 0.08 ENST00000381842.7
PRB3
proline rich protein BstNI subfamily 3
chrX_-_49080066 0.08 ENST00000634944.1
ENST00000423215.3
ENST00000465382.6
WDR45
WD repeat domain 45
chr12_-_76068933 0.08 ENST00000552056.5
NAP1L1
nucleosome assembly protein 1 like 1
chr12_+_4649097 0.07 ENST00000648836.1
ENST00000266544.10
ENSG00000255639.3
NDUFA9
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr20_+_46008900 0.07 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr9_-_19049319 0.07 ENST00000542071.2
ENST00000649457.1
SAXO1
stabilizer of axonemal microtubules 1
chr17_-_40994159 0.07 ENST00000391586.3
KRTAP3-3
keratin associated protein 3-3
chr2_-_165953750 0.07 ENST00000243344.8
ENST00000679799.1
ENST00000679840.1
ENST00000681606.1
ENST00000680448.1
TTC21B
tetratricopeptide repeat domain 21B
chr9_-_4666347 0.06 ENST00000381890.9
ENST00000682582.1
SPATA6L
spermatogenesis associated 6 like
chr7_-_88306880 0.06 ENST00000414498.1
ENST00000301959.9
ENST00000380079.9
STEAP4
STEAP4 metalloreductase
chr9_+_105662457 0.06 ENST00000334077.6
TAL2
TAL bHLH transcription factor 2
chr1_-_85708382 0.06 ENST00000370574.4
ENST00000431532.6
ZNHIT6
zinc finger HIT-type containing 6
chr1_+_207496229 0.05 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr12_+_12049840 0.05 ENST00000589718.5
BCL2L14
BCL2 like 14
chr9_-_110999458 0.04 ENST00000374430.6
LPAR1
lysophosphatidic acid receptor 1
chr16_+_3204247 0.04 ENST00000304646.2
OR1F1
olfactory receptor family 1 subfamily F member 1
chr17_-_43942472 0.04 ENST00000225992.8
PPY
pancreatic polypeptide
chr1_-_158330957 0.04 ENST00000451207.5
CD1B
CD1b molecule
chr16_-_20697680 0.04 ENST00000520010.6
ACSM1
acyl-CoA synthetase medium chain family member 1
chr12_+_12049855 0.04 ENST00000586576.5
ENST00000464885.6
BCL2L14
BCL2 like 14
chr2_-_27370009 0.04 ENST00000451130.6
EIF2B4
eukaryotic translation initiation factor 2B subunit delta
chr7_-_151210488 0.04 ENST00000644661.2
H2BE1
H2B.E variant histone 1
chr19_+_44914702 0.03 ENST00000592885.5
ENST00000589781.1
APOC1
apolipoprotein C1
chr6_-_31546552 0.03 ENST00000303892.10
ENST00000376151.4
ATP6V1G2
ATPase H+ transporting V1 subunit G2
chr22_+_41621977 0.03 ENST00000405506.2
XRCC6
X-ray repair cross complementing 6
chrM_+_7586 0.03 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr2_-_237414127 0.03 ENST00000472056.5
COL6A3
collagen type VI alpha 3 chain
chr1_+_40374648 0.02 ENST00000372708.5
SMAP2
small ArfGAP2
chr16_-_47459130 0.02 ENST00000565940.6
ITFG1
integrin alpha FG-GAP repeat containing 1
chr19_+_44914588 0.02 ENST00000592535.6
APOC1
apolipoprotein C1
chr21_+_29130630 0.01 ENST00000399926.5
ENST00000399928.6
MAP3K7CL
MAP3K7 C-terminal like
chr6_-_106325735 0.01 ENST00000635758.2
ENST00000369076.8
ENST00000636437.1
ATG5
autophagy related 5
chr4_-_87529460 0.01 ENST00000418378.5
SPARCL1
SPARC like 1
chr9_-_29739 0.01 ENST00000442898.5
WASHC1
WASH complex subunit 1
chr1_-_51990679 0.01 ENST00000371655.4
RAB3B
RAB3B, member RAS oncogene family
chr2_-_240820945 0.00 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
KIF1A
kinesin family member 1A
chr1_+_207496147 0.00 ENST00000400960.7
ENST00000367049.9
CR1
complement C3b/C4b receptor 1 (Knops blood group)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3 2.0 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 0.8 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 1.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 0.3 GO:0090427 activation of meiosis(GO:0090427)
0.2 1.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 2.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.2 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 1.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.2 GO:1903937 response to acrylamide(GO:1903937)
0.0 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0009631 cold acclimation(GO:0009631)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.8 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 5.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 2.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 2.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 2.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 5.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels