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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ARID5A

Z-value: 0.72

Motif logo

Transcription factors associated with ARID5A

Gene Symbol Gene ID Gene Info
ENSG00000196843.17 ARID5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID5Ahg38_v1_chr2_+_96536743_965367620.691.2e-04Click!

Activity profile of ARID5A motif

Sorted Z-values of ARID5A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID5A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_151357583 5.76 ENST00000243347.5
TNF alpha induced protein 6
chr5_+_119354771 3.72 ENST00000503646.1
TNF alpha induced protein 8
chr1_-_169734064 2.13 ENST00000333360.12
selectin E
chr9_-_120926752 1.94 ENST00000373887.8
TNF receptor associated factor 1
chr2_-_224947030 1.64 ENST00000409592.7
dedicator of cytokinesis 10
chr1_-_89065200 1.58 ENST00000370473.5
guanylate binding protein 1
chr1_-_89126066 1.58 ENST00000370466.4
guanylate binding protein 2
chr6_+_29099490 1.51 ENST00000641659.2
olfactory receptor family 2 subfamily J member 1
chr6_-_10415043 1.51 ENST00000379613.10
transcription factor AP-2 alpha
chr14_+_22070548 1.43 ENST00000390450.3
T cell receptor alpha variable 22
chr16_-_75556214 1.37 ENST00000568377.5
ENST00000565067.5
ENST00000258173.11
transmembrane protein 231
chr12_+_77830886 1.35 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr1_-_173050931 1.34 ENST00000404377.5
TNF superfamily member 18
chr2_-_174846405 1.33 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr7_-_22193824 1.29 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr2_-_174847015 1.24 ENST00000650938.1
chimerin 1
chr18_+_63887698 1.23 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr6_-_10414985 1.18 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr8_+_85177225 1.12 ENST00000418930.6
E2F transcription factor 5
chr21_-_34526850 1.08 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr2_+_102418642 1.01 ENST00000264260.6
interleukin 18 receptor accessory protein
chr2_+_102337148 0.98 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr4_-_68670648 0.92 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr2_-_24328113 0.91 ENST00000622089.4
intersectin 2
chr18_+_58149314 0.75 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr15_+_70936487 0.73 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr3_+_11154477 0.71 ENST00000431010.3
histamine receptor H1
chr4_-_176195563 0.68 ENST00000280191.7
spermatogenesis associated 4
chr1_-_154627945 0.64 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr12_+_9827472 0.64 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
killer cell lectin like receptor F1
chr6_-_169253835 0.64 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr5_+_126423363 0.63 ENST00000285689.8
GRAM domain containing 2B
chr18_+_31591869 0.62 ENST00000237014.8
transthyretin
chr16_-_48247533 0.60 ENST00000356608.7
ENST00000569991.1
ATP binding cassette subfamily C member 11
chr12_+_69825221 0.60 ENST00000552032.7
myelin regulatory factor like
chr19_-_43670153 0.59 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr5_+_55024250 0.55 ENST00000231009.3
granzyme K
chr6_+_46793379 0.54 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr17_-_3063607 0.54 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr11_+_55883297 0.51 ENST00000449290.6
tripartite motif-containing 51
chr1_+_40988513 0.51 ENST00000649215.1
CTP synthase 1
chr10_+_110005804 0.50 ENST00000360162.7
adducin 3
chr1_-_154627906 0.50 ENST00000679899.1
adenosine deaminase RNA specific
chr19_+_33374312 0.50 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr12_+_112125531 0.49 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chrX_+_48897919 0.48 ENST00000447146.7
ENST00000247140.8
polyglutamine binding protein 1
chr21_-_34526815 0.48 ENST00000492600.1
regulator of calcineurin 1
chr6_+_10528326 0.47 ENST00000379597.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr11_+_60429595 0.46 ENST00000528905.1
ENST00000528093.1
membrane spanning 4-domains A5
chr3_+_101827982 0.46 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr3_+_9649433 0.46 ENST00000353332.9
ENST00000420925.5
ENST00000296003.9
ENST00000351233.9
myotubularin related protein 14
chr1_+_86468902 0.45 ENST00000394711.2
chloride channel accessory 1
chr19_+_54502799 0.45 ENST00000301202.7
leukocyte associated immunoglobulin like receptor 2
chr2_+_167135901 0.44 ENST00000628543.2
xin actin binding repeat containing 2
chr19_+_54502867 0.42 ENST00000351841.2
leukocyte associated immunoglobulin like receptor 2
chr11_-_5324297 0.41 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr1_-_89270751 0.41 ENST00000370459.7
guanylate binding protein 5
chr1_+_116909869 0.41 ENST00000393203.3
prostaglandin F2 receptor inhibitor
chr7_+_16661182 0.41 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr3_+_97439603 0.41 ENST00000514100.5
EPH receptor A6
chr10_+_24466487 0.40 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr12_+_21131187 0.40 ENST00000256958.3
solute carrier organic anion transporter family member 1B1
chr4_-_70666492 0.40 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr18_+_58362467 0.40 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr1_-_100178215 0.39 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
leucine rich repeat containing 39
chr12_+_69825273 0.38 ENST00000547771.6
myelin regulatory factor like
chr1_-_212847649 0.38 ENST00000332912.3
spermatogenesis associated 45
chr19_+_35748549 0.38 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr11_-_48983826 0.37 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr3_-_150703943 0.37 ENST00000491361.5
glutamate rich 6
chr3_+_148730100 0.36 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr2_+_102001966 0.36 ENST00000457817.5
interleukin 1 receptor type 2
chr3_-_151278535 0.36 ENST00000309170.8
purinergic receptor P2Y14
chr2_-_10447771 0.36 ENST00000405333.5
ENST00000443218.1
ornithine decarboxylase 1
chr4_-_47981535 0.35 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr2_-_179861604 0.35 ENST00000410066.7
zinc finger protein 385B
chr4_+_54229261 0.35 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chrX_+_80420466 0.34 ENST00000308293.5
terminal nucleotidyltransferase 5D
chr6_-_26271815 0.34 ENST00000614378.1
H3 clustered histone 8
chr6_-_49744378 0.33 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr6_-_49744434 0.33 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr6_+_30067530 0.33 ENST00000376765.6
ENST00000376763.5
protein phosphatase 1 regulatory inhibitor subunit 11
chr1_-_197067234 0.32 ENST00000367412.2
coagulation factor XIII B chain
chr1_+_248231417 0.32 ENST00000641868.1
olfactory receptor family 2 subfamily M member 4
chrX_+_48897900 0.32 ENST00000376566.8
ENST00000376563.5
polyglutamine binding protein 1
chr19_+_3224701 0.32 ENST00000541430.6
CUGBP Elav-like family member 5
chr7_+_116953306 0.32 ENST00000265437.9
ENST00000393451.7
suppression of tumorigenicity 7
chr3_+_75906666 0.32 ENST00000487694.7
ENST00000602589.5
roundabout guidance receptor 2
chr21_-_18403754 0.32 ENST00000284885.8
transmembrane serine protease 15
chr2_-_73779968 0.32 ENST00000452812.1
ENST00000443070.5
ENST00000272444.7
dual specificity phosphatase 11
chr11_-_31810991 0.32 ENST00000640684.1
paired box 6
chr8_+_36784324 0.31 ENST00000523973.5
ENST00000399881.8
potassium calcium-activated channel subfamily U member 1
chr9_-_92482350 0.31 ENST00000375543.2
asporin
chr4_+_186227501 0.31 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr6_+_10555787 0.31 ENST00000316170.9
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr9_-_34381578 0.31 ENST00000379133.7
chromosome 9 open reading frame 24
chr5_-_132543513 0.31 ENST00000231454.6
interleukin 5
chr2_+_89936859 0.31 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr6_-_49866453 0.30 ENST00000507853.5
cysteine rich secretory protein 1
chr12_+_10307950 0.30 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr20_+_31475278 0.30 ENST00000201979.3
RRAD and GEM like GTPase 1
chr7_-_32071397 0.29 ENST00000396184.7
ENST00000396189.2
ENST00000321453.12
phosphodiesterase 1C
chr12_-_124989053 0.29 ENST00000308736.7
DEAH-box helicase 37
chrX_+_83861126 0.29 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr1_+_12857086 0.29 ENST00000240189.2
PRAME family member 2
chr5_-_170389349 0.29 ENST00000274629.9
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr10_+_69088096 0.28 ENST00000242465.4
serglycin
chrX_+_154762729 0.28 ENST00000620277.4
dyskerin pseudouridine synthase 1
chr11_-_6030758 0.28 ENST00000641900.1
olfactory receptor family 56 subfamily A member 1
chr9_-_34381531 0.27 ENST00000379124.5
ENST00000379126.7
ENST00000379127.1
chromosome 9 open reading frame 24
chr6_-_152563271 0.27 ENST00000535896.7
ENST00000672122.1
spectrin repeat containing nuclear envelope protein 1
chr1_+_21977014 0.27 ENST00000337107.11
chymotrypsin like elastase 3B
chr14_-_74875998 0.27 ENST00000556489.4
ENST00000673765.1
prospero homeobox 2
chrX_+_65588368 0.27 ENST00000609672.5
moesin
chr18_+_31376777 0.27 ENST00000308128.9
ENST00000359747.4
desmoglein 4
chr11_-_31811231 0.27 ENST00000438681.6
paired box 6
chr10_-_60572599 0.26 ENST00000503366.5
ankyrin 3
chr12_-_16600703 0.26 ENST00000616247.4
LIM domain only 3
chr8_-_86069662 0.26 ENST00000276616.3
protein serine kinase H2
chr7_+_16646131 0.26 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
basic leucine zipper and W2 domains 2
chr11_-_102724945 0.26 ENST00000236826.8
matrix metallopeptidase 8
chr3_+_14675128 0.26 ENST00000435614.5
ENST00000253697.8
ENST00000412910.1
chromosome 3 open reading frame 20
chr8_-_28490220 0.25 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
F-box protein 16
chr1_+_170935526 0.25 ENST00000367758.7
ENST00000367759.9
maestro heat like repeat family member 9
chr20_+_38962299 0.25 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr2_-_227379297 0.25 ENST00000304568.4
transmembrane 4 L six family member 20
chr5_+_141370236 0.25 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr16_+_30748241 0.24 ENST00000565924.5
ENST00000424889.7
phosphorylase kinase catalytic subunit gamma 2
chr11_+_61228377 0.24 ENST00000537932.5
pepsinogen A4
chr3_+_73061659 0.24 ENST00000533473.1
endogenous Bornavirus like nucleoprotein 2
chr6_+_116399395 0.24 ENST00000644499.1
novel protein
chr19_-_43820598 0.24 ENST00000594049.5
ENST00000414615.6
LY6/PLAUR domain containing 5
chr18_-_46964408 0.24 ENST00000676383.1
elongin A3 family member D
chr2_-_212124901 0.24 ENST00000402597.6
erb-b2 receptor tyrosine kinase 4
chr14_+_90256542 0.24 ENST00000261303.13
ENST00000543772.2
proteasome 26S subunit, ATPase 1
chr19_+_10013468 0.24 ENST00000591589.3
retinol dehydrogenase 8
chr20_+_142573 0.23 ENST00000382398.4
defensin beta 126
chr4_+_183905266 0.23 ENST00000308497.9
storkhead box 2
chr6_-_26056460 0.23 ENST00000343677.4
H1.2 linker histone, cluster member
chr19_+_35641728 0.23 ENST00000619399.4
ENST00000379026.6
ENST00000379023.8
ENST00000402764.6
ENST00000479824.5
ETS variant transcription factor 2
chr15_+_94297939 0.23 ENST00000357742.9
multiple C2 and transmembrane domain containing 2
chr15_-_72231583 0.23 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr6_-_49866527 0.23 ENST00000335847.9
cysteine rich secretory protein 1
chrX_+_41724174 0.23 ENST00000302548.5
G protein-coupled receptor 82
chr19_+_54497879 0.23 ENST00000412608.5
ENST00000610651.1
leukocyte associated immunoglobulin like receptor 2
chr4_+_70383123 0.22 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr9_+_113444725 0.22 ENST00000374140.6
regulator of G protein signaling 3
chr10_+_96000091 0.22 ENST00000424464.5
ENST00000410012.6
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr19_-_2292024 0.22 ENST00000585527.1
leucine rich repeat and Ig domain containing 3
chr14_+_56117702 0.22 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr12_+_25958891 0.22 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
Ras association domain family member 8
chrX_+_22032301 0.22 ENST00000379374.5
phosphate regulating endopeptidase homolog X-linked
chr7_+_134843884 0.22 ENST00000445569.6
caldesmon 1
chr5_-_58999885 0.21 ENST00000317118.12
phosphodiesterase 4D
chr5_+_141387698 0.21 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr3_+_171843337 0.21 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr1_+_117420597 0.21 ENST00000449370.6
mannosidase alpha class 1A member 2
chr3_-_87276577 0.20 ENST00000344265.8
ENST00000350375.7
POU class 1 homeobox 1
chr4_+_69931066 0.20 ENST00000246891.9
casein alpha s1
chr12_+_9971402 0.20 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr19_-_893172 0.20 ENST00000325464.6
ENST00000312090.10
mediator complex subunit 16
chr9_+_107306459 0.20 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr4_+_118850668 0.19 ENST00000610556.4
synaptopodin 2
chr6_-_130222813 0.19 ENST00000437477.6
ENST00000439090.7
sterile alpha motif domain containing 3
chr11_-_31811034 0.19 ENST00000638250.1
paired box 6
chr11_-_31811112 0.19 ENST00000640242.1
ENST00000640613.1
ENST00000606377.7
paired box 6
chr4_+_67558719 0.19 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr5_+_58491451 0.19 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr3_+_178558700 0.19 ENST00000432997.5
ENST00000455865.5
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr1_+_158845798 0.19 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr5_+_141397942 0.19 ENST00000617380.2
ENST00000621169.1
protocadherin gamma subfamily B, 5
chr5_+_58491427 0.19 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GRB2 binding adaptor protein, transmembrane
chr4_+_109912877 0.19 ENST00000265171.10
ENST00000509793.5
ENST00000652245.1
epidermal growth factor
chr13_-_110242694 0.18 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
collagen type IV alpha 1 chain
chr11_-_31811140 0.18 ENST00000639916.1
paired box 6
chrX_+_86714623 0.18 ENST00000484479.1
dachshund family transcription factor 2
chr4_+_70226116 0.18 ENST00000317987.6
follicular dendritic cell secreted protein
chr10_+_46375645 0.18 ENST00000622769.4
annexin A8 like 1
chr3_-_167474026 0.18 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr10_+_46375619 0.18 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr8_-_51809414 0.18 ENST00000356297.5
peroxidasin like
chr10_+_27532521 0.18 ENST00000683924.1
RAB18, member RAS oncogene family
chr1_-_66801276 0.18 ENST00000304526.3
insulin like 5
chr10_+_94683722 0.18 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr2_-_32264853 0.18 ENST00000402280.6
NLR family CARD domain containing 4
chr22_+_25219633 0.18 ENST00000398215.3
crystallin beta B2
chr11_-_114595777 0.17 ENST00000375478.4
neurexophilin and PC-esterase domain family member 4
chr14_+_67720842 0.17 ENST00000267502.3
retinol dehydrogenase 12
chr6_+_122996227 0.17 ENST00000275162.10
clavesin 2
chr6_+_30328889 0.17 ENST00000396547.5
ENST00000623385.3
tripartite motif containing 39
TRIM39-RPP21 readthrough
chrX_-_101386166 0.17 ENST00000308731.8
ENST00000372880.5
Bruton tyrosine kinase
chr10_+_133394094 0.17 ENST00000477902.6
mitochondrial ribosome associated GTPase 1
chr11_+_89924064 0.17 ENST00000623787.3
tripartite motif containing 49D2
chr19_+_7030578 0.16 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr13_+_42781578 0.16 ENST00000313851.3
family with sequence similarity 216 member B
chr1_+_171185293 0.16 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr11_-_5269933 0.16 ENST00000396895.3
hemoglobin subunit epsilon 1
chr4_-_99352730 0.16 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr2_-_68952880 0.16 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr13_+_42781547 0.16 ENST00000537894.5
family with sequence similarity 216 member B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0003409 optic cup structural organization(GO:0003409)
0.3 1.3 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.3 1.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 1.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 5.8 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 1.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.9 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 0.3 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.4 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 2.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 1.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.3 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.3 GO:1903413 cellular response to bile acid(GO:1903413)
0.1 0.2 GO:0002368 positive regulation of type I hypersensitivity(GO:0001812) B cell selection(GO:0002339) B cell cytokine production(GO:0002368)
0.1 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 1.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 2.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.4 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:2000078 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) telomerase RNA stabilization(GO:0090669)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 1.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:1900127 negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:1904021 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 1.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 3.7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.5 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 2.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.4 GO:0071756 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.3 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 6.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.1 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 1.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 2.1 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 5.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0019862 IgA binding(GO:0019862)
0.1 3.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.6 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 4.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 1.3 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 2.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 6.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway