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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ATF6

Z-value: 0.88

Motif logo

Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ENSG00000118217.7 ATF6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg38_v1_chr1_+_161766282_1617663030.301.4e-01Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_129964240 3.12 ENST00000440978.2
ENST00000355311.10
EBF transcription factor 3
chr13_-_48533165 2.01 ENST00000430805.6
ENST00000544492.5
ENST00000544904.3
RCC1 and BTB domain containing protein 2
chr3_+_37861849 1.81 ENST00000273179.10
CTD small phosphatase like
chr7_+_155297776 1.74 ENST00000344756.8
ENST00000425172.1
ENST00000340368.9
ENST00000342407.5
insulin induced gene 1
chr3_+_37861926 1.64 ENST00000443503.6
CTD small phosphatase like
chr17_-_68955332 1.56 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr13_-_48533069 1.53 ENST00000344532.8
RCC1 and BTB domain containing protein 2
chr22_-_19881163 1.51 ENST00000485358.5
thioredoxin reductase 2
chr10_+_35126791 1.45 ENST00000474362.5
ENST00000374721.7
cAMP responsive element modulator
chr10_+_35127162 1.40 ENST00000354759.7
cAMP responsive element modulator
chr11_-_119364166 1.36 ENST00000525735.1
ubiquitin specific peptidase 2
chr10_+_35127023 1.20 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
cAMP responsive element modulator
chr8_+_30095400 1.18 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr10_+_110497898 1.13 ENST00000369583.4
dual specificity phosphatase 5
chr8_+_30095649 1.11 ENST00000518192.5
leptin receptor overlapping transcript like 1
chr7_+_16753731 1.03 ENST00000262067.5
tetraspanin 13
chr2_+_28392802 1.02 ENST00000379619.5
ENST00000264716.9
FOS like 2, AP-1 transcription factor subunit
chr17_+_67825664 0.93 ENST00000321892.8
bromodomain PHD finger transcription factor
chr16_+_53130921 0.92 ENST00000564845.5
chromodomain helicase DNA binding protein 9
chr7_+_12686849 0.91 ENST00000396662.5
ENST00000356797.7
ENST00000396664.2
ADP ribosylation factor like GTPase 4A
chr10_+_35127295 0.90 ENST00000489321.5
ENST00000427847.6
ENST00000374728.7
ENST00000345491.7
ENST00000487132.5
cAMP responsive element modulator
chr3_-_187745460 0.88 ENST00000406870.7
BCL6 transcription repressor
chr4_-_148444674 0.88 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr12_+_56267249 0.85 ENST00000433805.6
coenzyme Q10A
chr1_+_32539418 0.85 ENST00000373510.9
ENST00000316459.4
zinc finger and BTB domain containing 8A
chr12_-_109573482 0.85 ENST00000540016.5
ENST00000545712.7
metabolism of cobalamin associated B
chr14_-_23352872 0.84 ENST00000397267.5
solute carrier family 22 member 17
chr12_+_56266934 0.84 ENST00000308197.10
coenzyme Q10A
chr17_-_41811930 0.83 ENST00000393928.6
prolyl 3-hydroxylase family member 4 (inactive)
chr14_-_23352741 0.81 ENST00000354772.9
solute carrier family 22 member 17
chr7_+_116953379 0.80 ENST00000393449.5
suppression of tumorigenicity 7
chr2_+_202634960 0.78 ENST00000392238.3
family with sequence similarity 117 member B
chr3_+_184812138 0.78 ENST00000287546.8
VPS8 subunit of CORVET complex
chr3_+_184812159 0.78 ENST00000625842.3
ENST00000436792.6
ENST00000446204.6
ENST00000422105.5
VPS8 subunit of CORVET complex
chr4_-_39638893 0.77 ENST00000511809.5
ENST00000505729.1
small integral membrane protein 14
chr1_+_153776596 0.76 ENST00000458027.5
solute carrier family 27 member 3
chr17_-_51260032 0.76 ENST00000586178.6
mbt domain containing 1
chr17_-_41812586 0.75 ENST00000355468.7
ENST00000590496.1
prolyl 3-hydroxylase family member 4 (inactive)
chr9_+_35906179 0.74 ENST00000354323.3
histidine rich carboxyl terminus 1
chr7_+_92057602 0.74 ENST00000491695.2
A-kinase anchoring protein 9
chr7_+_116953514 0.73 ENST00000446490.5
suppression of tumorigenicity 7
chr7_+_116953482 0.73 ENST00000323984.8
ENST00000417919.5
suppression of tumorigenicity 7
chr13_-_100674774 0.70 ENST00000328767.9
transmembrane O-mannosyltransferase targeting cadherins 4
chr19_-_42255119 0.70 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr7_-_101165114 0.69 ENST00000445482.2
VGF nerve growth factor inducible
chr13_-_100674813 0.69 ENST00000376234.7
ENST00000423847.1
transmembrane O-mannosyltransferase targeting cadherins 4
chr7_+_116953238 0.67 ENST00000393446.6
suppression of tumorigenicity 7
chr13_-_100674787 0.67 ENST00000342624.10
transmembrane O-mannosyltransferase targeting cadherins 4
chr17_-_18363451 0.65 ENST00000354098.7
serine hydroxymethyltransferase 1
chr1_+_222618075 0.64 ENST00000344922.10
MIA SH3 domain ER export factor 3
chr15_+_96325935 0.64 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr5_-_172454308 0.63 ENST00000636523.1
ENST00000519643.5
SH3 and PX domains 2B
chr12_+_78863962 0.63 ENST00000393240.7
synaptotagmin 1
chr18_+_13218769 0.63 ENST00000677055.1
ENST00000399848.7
low density lipoprotein receptor class A domain containing 4
chr3_-_129439925 0.62 ENST00000429544.7
methyl-CpG binding domain 4, DNA glycosylase
chr8_-_38269116 0.62 ENST00000529359.5
phospholipid phosphatase 5
chr3_-_129440007 0.60 ENST00000503197.5
ENST00000249910.5
ENST00000507208.1
ENST00000393278.6
methyl-CpG binding domain 4, DNA glycosylase
chr6_-_6007511 0.59 ENST00000616243.1
neuritin 1
chr8_+_96645221 0.58 ENST00000220763.10
carboxypeptidase Q
chr3_+_100492548 0.58 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr12_+_13044371 0.58 ENST00000197268.13
family with sequence similarity 234 member B
chr9_+_128882502 0.57 ENST00000259324.5
leucine rich repeat containing 8 VRAC subunit A
chr11_-_78079819 0.56 ENST00000534029.5
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000281031.5
ENST00000528251.1
ENST00000530054.1
NADH:ubiquinone oxidoreductase subunit C2
NDUFC2-KCTD14 readthrough
chr3_+_158801926 0.55 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chr22_+_46674593 0.54 ENST00000408031.1
GRAM domain containing 4
chr13_+_113584683 0.54 ENST00000375370.10
transcription factor Dp-1
chr17_-_81911367 0.54 ENST00000538936.7
ENST00000538721.6
ENST00000573636.6
ENST00000571105.5
ENST00000576343.5
ENST00000572473.1
phosphate cytidylyltransferase 2, ethanolamine
chr17_+_4739791 0.53 ENST00000433935.6
zinc finger MYND-type containing 15
chr9_-_76906090 0.53 ENST00000376718.8
prune homolog 2 with BCH domain
chr6_-_6006878 0.51 ENST00000244766.7
neuritin 1
chr17_+_68515399 0.51 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr2_+_189784085 0.50 ENST00000639501.1
ENST00000624204.3
ENST00000432292.7
ENST00000418224.7
ENST00000618056.4
PMS1 homolog 1, mismatch repair system component
chr17_-_59106801 0.50 ENST00000393065.6
ENST00000262294.12
ENST00000393066.7
tripartite motif containing 37
chrX_-_101617921 0.50 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
armadillo repeat containing X-linked 6
chr15_-_51738095 0.50 ENST00000560491.2
LysM domain containing 2
chr7_-_101165558 0.49 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr9_-_75028274 0.49 ENST00000376834.8
carnosine N-methyltransferase 1
chr22_-_39152622 0.48 ENST00000216133.10
chromobox 7
chr4_-_107720189 0.48 ENST00000265174.5
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr7_-_87220567 0.48 ENST00000433078.5
transmembrane protein 243
chr17_+_28744034 0.48 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr10_-_92574027 0.47 ENST00000650060.1
ENST00000265986.11
ENST00000679089.1
ENST00000676540.1
ENST00000678673.1
ENST00000677079.1
insulin degrading enzyme
chr16_+_30378312 0.47 ENST00000528032.5
ENST00000622647.3
zinc finger protein 48
chr14_+_64503943 0.47 ENST00000556965.1
ENST00000554015.5
zinc finger and BTB domain containing 1
chr16_+_2969307 0.47 ENST00000576565.1
ENST00000318782.9
progestin and adipoQ receptor family member 4
chr16_+_2969270 0.47 ENST00000293978.12
progestin and adipoQ receptor family member 4
chr9_-_76906041 0.47 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr5_+_79236092 0.47 ENST00000396137.5
junction mediating and regulatory protein, p53 cofactor
chr3_-_33718049 0.46 ENST00000468888.6
cytoplasmic linker associated protein 2
chr6_-_69796564 0.46 ENST00000370570.6
LMBR1 domain containing 1
chr16_+_2969548 0.46 ENST00000572687.1
progestin and adipoQ receptor family member 4
chrX_-_101659796 0.45 ENST00000431597.5
ENST00000458024.5
ENST00000413506.5
ENST00000440675.5
ENST00000328766.9
ENST00000356824.9
armadillo repeat containing X-linked 2
chr15_-_72118114 0.45 ENST00000356056.10
ENST00000569314.1
myosin IXA
chr1_-_77683356 0.45 ENST00000414381.5
ENST00000370798.5
zinc finger ZZ-type containing 3
chr18_+_7567266 0.44 ENST00000580170.6
protein tyrosine phosphatase receptor type M
chr10_+_100999287 0.43 ENST00000370220.1
leucine zipper tumor suppressor 2
chr9_+_130579556 0.43 ENST00000319725.10
far upstream element binding protein 3
chrX_-_120559889 0.43 ENST00000371323.3
cullin 4B
chr17_+_4143168 0.43 ENST00000577075.6
ENST00000301391.8
ENST00000575251.5
cytochrome b5 domain containing 2
chr14_-_49586325 0.42 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
ribosomal protein S29
chr5_-_142012973 0.42 ENST00000503794.5
ENST00000510194.5
ENST00000504424.1
ENST00000513454.5
ENST00000311337.11
ENST00000503229.5
ENST00000500692.6
ENST00000504139.5
ENST00000505689.5
glucosamine-6-phosphate deaminase 1
chr14_+_67619911 0.41 ENST00000261783.4
arginase 2
chr6_+_32969345 0.41 ENST00000678250.1
bromodomain containing 2
chr13_+_112690168 0.41 ENST00000375630.6
ENST00000487903.5
ATPase phospholipid transporting 11A
chr14_+_96039328 0.41 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chr4_-_169010241 0.41 ENST00000504480.5
ENST00000306193.8
carbonyl reductase 4
chr9_+_128276222 0.40 ENST00000608796.6
ENST00000419867.7
ENST00000418976.2
SWI5 homologous recombination repair protein
chr16_+_22206255 0.40 ENST00000263026.10
eukaryotic elongation factor 2 kinase
chr1_+_156860857 0.40 ENST00000524377.7
neurotrophic receptor tyrosine kinase 1
chr13_+_112690032 0.40 ENST00000375645.8
ATPase phospholipid transporting 11A
chr1_+_156860886 0.40 ENST00000358660.3
ENST00000675461.1
neurotrophic receptor tyrosine kinase 1
chr5_+_41904329 0.40 ENST00000381647.7
ENST00000612065.1
chromosome 5 open reading frame 51
chr11_-_114400417 0.40 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr7_+_65873324 0.39 ENST00000434382.2
vitamin K epoxide reductase complex subunit 1 like 1
chr5_+_69093943 0.39 ENST00000621204.4
solute carrier family 30 member 5
chr1_+_156860815 0.39 ENST00000368196.7
neurotrophic receptor tyrosine kinase 1
chr3_-_33718207 0.39 ENST00000359576.9
ENST00000682230.1
ENST00000399362.8
cytoplasmic linker associated protein 2
chr5_+_100535317 0.39 ENST00000312637.5
family with sequence similarity 174 member A
chr7_+_73433761 0.38 ENST00000344575.5
frizzled class receptor 9
chr5_+_69093980 0.38 ENST00000380860.8
ENST00000396591.8
ENST00000504103.5
ENST00000502979.1
solute carrier family 30 member 5
chr21_-_37072688 0.37 ENST00000464265.5
ENST00000399102.5
phosphatidylinositol glycan anchor biosynthesis class P
chr4_+_107824555 0.37 ENST00000394684.8
sphingomyelin synthase 2
chr4_-_39638846 0.37 ENST00000295958.10
small integral membrane protein 14
chr14_+_77320996 0.37 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
glutathione S-transferase zeta 1
chr11_-_67469210 0.37 ENST00000393877.3
ENST00000308022.7
transmembrane protein 134
chr6_+_32969165 0.36 ENST00000496118.2
ENST00000449085.4
bromodomain containing 2
chr9_-_124941054 0.36 ENST00000373555.9
golgin A1
chr21_+_37073213 0.36 ENST00000418766.5
ENST00000450533.5
ENST00000438055.5
ENST00000355666.5
ENST00000540756.5
ENST00000399010.5
tetratricopeptide repeat domain 3
chr16_-_69339493 0.36 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
component of oligomeric golgi complex 8
chr11_-_119057105 0.35 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
hypoxia up-regulated 1
chr8_+_22565236 0.34 ENST00000523900.5
sorbin and SH3 domain containing 3
chr6_-_84227596 0.33 ENST00000257766.8
centrosomal protein 162
chr3_+_45026296 0.33 ENST00000296130.5
C-type lectin domain family 3 member B
chr20_+_41028814 0.33 ENST00000361337.3
DNA topoisomerase I
chrX_-_34657274 0.33 ENST00000275954.4
transmembrane protein 47
chr9_+_68705414 0.33 ENST00000541509.5
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr11_+_114059755 0.33 ENST00000684295.1
zinc finger and BTB domain containing 16
chr6_+_24775413 0.33 ENST00000378054.6
ENST00000620958.4
ENST00000476555.5
geminin DNA replication inhibitor
chr3_-_121749704 0.33 ENST00000393667.7
ENST00000340645.9
ENST00000614479.4
golgin B1
chr11_-_119057218 0.32 ENST00000652093.1
hypoxia up-regulated 1
chr8_+_60516927 0.32 ENST00000531289.5
RAB2A, member RAS oncogene family
chr17_-_18363504 0.32 ENST00000583780.1
ENST00000316694.8
ENST00000352886.10
serine hydroxymethyltransferase 1
chr6_-_84227634 0.32 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr14_-_64503775 0.32 ENST00000608382.6
zinc finger and BTB domain containing 25
chr2_+_148021083 0.32 ENST00000642680.2
methyl-CpG binding domain protein 5
chr8_-_38269157 0.32 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
phospholipid phosphatase 5
chr6_-_109381739 0.31 ENST00000504373.2
CD164 molecule
chr11_-_117232033 0.31 ENST00000524507.6
ENST00000320934.8
ENST00000532301.5
ENST00000676339.1
ENST00000540028.5
proprotein convertase subtilisin/kexin type 7
chr19_+_48872412 0.31 ENST00000200453.6
protein phosphatase 1 regulatory subunit 15A
chr3_+_129440082 0.31 ENST00000347300.6
ENST00000296266.7
intraflagellar transport 122
chr6_-_33789090 0.31 ENST00000614475.4
ENST00000293760.10
LEM domain nuclear envelope protein 2
chr14_+_93185304 0.31 ENST00000415050.3
transmembrane protein 251
chr2_+_218880844 0.31 ENST00000258411.8
Wnt family member 10A
chr22_-_38700920 0.31 ENST00000456626.1
ENST00000412832.1
ENST00000683374.1
Josephin domain containing 1
chr21_-_37073170 0.30 ENST00000399098.5
phosphatidylinositol glycan anchor biosynthesis class P
chr4_+_78776340 0.30 ENST00000502613.3
ENST00000502871.5
BMP2 inducible kinase
chr15_-_82349437 0.30 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
golgin A6 family like 10
chr17_+_46295099 0.30 ENST00000393465.7
ENST00000320254.5
leucine rich repeat containing 37A
chr3_+_129440196 0.30 ENST00000507564.5
ENST00000348417.7
ENST00000504021.5
ENST00000349441.6
intraflagellar transport 122
chr6_+_32968557 0.30 ENST00000374825.9
bromodomain containing 2
chr3_+_169966764 0.29 ENST00000337002.9
ENST00000480708.5
SEC62 homolog, preprotein translocation factor
chr2_+_148021001 0.29 ENST00000407073.5
methyl-CpG binding domain protein 5
chr7_-_6272639 0.29 ENST00000396741.3
cytohesin 3
chr4_+_128061275 0.29 ENST00000512292.5
ENST00000508819.5
ENST00000326639.11
ENST00000394288.7
La ribonucleoprotein 1B
chr15_-_23447234 0.29 ENST00000312015.6
ENST00000345070.5
ENST00000567107.6
golgin A6 family like 2
chr2_+_10044175 0.29 ENST00000440320.5
ENST00000535335.1
Kruppel like factor 11
chr2_-_27119012 0.29 ENST00000312734.8
cell growth regulator with EF-hand domain 1
chr11_+_28110275 0.28 ENST00000303459.10
ENST00000634762.1
ENST00000634721.1
methyltransferase like 15
chr17_+_47971105 0.28 ENST00000338399.9
ENST00000578018.5
ENST00000579175.5
CDK5 regulatory subunit associated protein 3
chr11_-_119057185 0.28 ENST00000614668.4
ENST00000617285.5
hypoxia up-regulated 1
chr15_+_75843307 0.27 ENST00000569423.5
ubiquitin conjugating enzyme E2 Q2
chr21_-_37072997 0.27 ENST00000430792.1
ENST00000399103.5
phosphatidylinositol glycan anchor biosynthesis class P
chr2_-_27489716 0.27 ENST00000260570.8
ENST00000675690.1
intraflagellar transport 172
chr2_-_27119099 0.27 ENST00000402550.5
ENST00000402394.6
cell growth regulator with EF-hand domain 1
chr1_-_23825402 0.27 ENST00000235958.4
ENST00000436439.6
ENST00000374490.8
3-hydroxy-3-methylglutaryl-CoA lyase
chr2_-_189784297 0.27 ENST00000409519.5
ENST00000458355.1
ENST00000392349.9
ORMDL sphingolipid biosynthesis regulator 1
chr1_-_77682639 0.26 ENST00000370801.8
ENST00000433749.5
zinc finger ZZ-type containing 3
chr11_+_32091065 0.26 ENST00000054950.4
reticulocalbin 1
chr15_-_72783685 0.26 ENST00000456471.3
ENST00000311669.12
ADP dependent glucokinase
chr3_-_126357399 0.26 ENST00000296233.4
Kruppel like factor 15
chr16_+_425599 0.25 ENST00000262305.9
RAB11 family interacting protein 3
chr2_+_171999937 0.25 ENST00000315796.5
methionyl aminopeptidase type 1D, mitochondrial
chr2_-_189784356 0.25 ENST00000392350.7
ORMDL sphingolipid biosynthesis regulator 1
chr21_-_37073019 0.25 ENST00000360525.9
phosphatidylinositol glycan anchor biosynthesis class P
chr1_-_15524183 0.25 ENST00000333868.10
ENST00000440484.1
caspase 9
chr12_-_107093509 0.25 ENST00000008527.10
cryptochrome circadian regulator 1
chr22_-_23751080 0.25 ENST00000341976.5
zinc finger protein 70
chrX_+_103376389 0.25 ENST00000372645.3
ENST00000372635.1
brain expressed X-linked 3
chr14_+_90061979 0.25 ENST00000282146.5
potassium two pore domain channel subfamily K member 13
chr3_-_139389604 0.25 ENST00000515006.5
ENST00000510181.6
ENST00000333188.10
ENST00000513274.5
ENST00000514508.2
ENST00000503326.6
ENST00000507777.6
ENST00000512242.6
ENST00000512153.5
ENST00000512309.2
COPI coat complex subunit beta 2
chr11_-_67504252 0.25 ENST00000533391.5
ENST00000534749.5
ENST00000532703.5
phosphatidylinositol transfer protein membrane associated 1
chr7_-_6272575 0.24 ENST00000350796.8
cytohesin 3
chr10_-_37976589 0.24 ENST00000302609.8
zinc finger protein 25
chr3_+_50269140 0.24 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr4_-_1248976 0.24 ENST00000514210.5
ENST00000382952.8
ENST00000290921.10
C-terminal binding protein 1
chr14_+_49620750 0.24 ENST00000305386.4
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr9_-_87974667 0.23 ENST00000375883.7
cyclin dependent kinase 20
chr17_+_44899695 0.23 ENST00000410006.6
ENST00000357776.6
ENST00000417826.3
ENST00000410027.5
ENST00000412523.3
coiled-coil domain containing 103
family with sequence similarity 187 member A
chrX_+_103376887 0.23 ENST00000372634.1
brain expressed X-linked 3
chr11_-_78079773 0.23 ENST00000612612.5
ENST00000614236.2
NDUFC2-KCTD14 readthrough

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 1.6 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 2.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 0.9 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.2 0.8 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 1.2 GO:0021553 olfactory nerve development(GO:0021553)
0.2 0.9 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.5 GO:0035498 carnosine metabolic process(GO:0035498)
0.2 1.0 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.6 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.5 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.5 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.5 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.6 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.6 GO:0060399 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0038016 insulin receptor internalization(GO:0038016)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 1.4 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.6 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.7 GO:1904179 osteoblast fate commitment(GO:0002051) regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179)
0.1 0.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 1.2 GO:0045008 depyrimidination(GO:0045008)
0.1 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.8 GO:0006824 cobalt ion transport(GO:0006824) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 1.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 4.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.2 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 1.2 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.5 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.4 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 1.5 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.6 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515) midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 3.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0030638 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:1904781 regulation of centriole-centriole cohesion(GO:0030997) positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0033263 CORVET complex(GO:0033263)
0.3 1.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.7 GO:0044307 dendritic branch(GO:0044307)
0.2 0.5 GO:0043293 apoptosome(GO:0043293)
0.1 0.6 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 1.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.0 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 4.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.2 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.2 1.0 GO:0070905 serine binding(GO:0070905)
0.2 1.2 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.2 1.9 GO:0048039 ubiquinone binding(GO:0048039)
0.2 0.7 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.2 0.5 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.2 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
0.1 0.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.4 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.9 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.9 GO:0051010 dystroglycan binding(GO:0002162) microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:1990247 pre-mRNA intronic binding(GO:0097157) N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism