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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for AUUGCAC

Z-value: 0.68

Motif logo

logo of

miRNA associated with seed AUUGCAC

NamemiRBASE accession
hsa-miR-25-3p
MIMAT0000081
hsa-miR-32-5p
MIMAT0000090
hsa-miR-363-3p
MIMAT0000707
hsa-miR-367-3p
MIMAT0000719
hsa-miR-92a-3p
MIMAT0000092
hsa-miR-92b-3p
MIMAT0003218

Activity profile of AUUGCAC motif

Sorted Z-values of AUUGCAC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AUUGCAC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_123135938 2.07 ENST00000357878.7
HMX3
H6 family homeobox 3
chr3_+_20040437 1.87 ENST00000263754.5
KAT2B
lysine acetyltransferase 2B
chr8_-_92103217 1.84 ENST00000615601.4
ENST00000523629.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr12_-_94650506 1.59 ENST00000261226.9
TMCC3
transmembrane and coiled-coil domain family 3
chr16_-_88706353 1.56 ENST00000567844.1
ENST00000312838.9
RNF166
ring finger protein 166
chr18_-_25352116 1.38 ENST00000584787.5
ENST00000538137.6
ENST00000361524.8
ZNF521
zinc finger protein 521
chr2_+_45651650 1.31 ENST00000306156.8
PRKCE
protein kinase C epsilon
chr9_-_14314067 1.12 ENST00000397575.7
NFIB
nuclear factor I B
chr17_-_50866347 1.12 ENST00000499247.3
TOB1
transducer of ERBB2, 1
chr3_-_128493173 1.11 ENST00000498200.1
ENST00000341105.7
GATA2
GATA binding protein 2
chr5_-_91383310 1.03 ENST00000265138.4
ARRDC3
arrestin domain containing 3
chr6_+_16129077 1.00 ENST00000356840.8
ENST00000349606.4
MYLIP
myosin regulatory light chain interacting protein
chr4_+_133149278 0.97 ENST00000264360.7
PCDH10
protocadherin 10
chr18_-_48950960 0.97 ENST00000262158.8
SMAD7
SMAD family member 7
chr6_+_15246054 0.95 ENST00000341776.7
JARID2
jumonji and AT-rich interaction domain containing 2
chr6_-_16761447 0.94 ENST00000244769.8
ENST00000436367.6
ATXN1
ataxin 1
chr21_-_43427131 0.90 ENST00000270162.8
SIK1
salt inducible kinase 1
chr11_+_123525822 0.89 ENST00000322282.11
ENST00000529750.5
GRAMD1B
GRAM domain containing 1B
chr7_+_107044689 0.88 ENST00000265717.5
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
chr6_+_107490103 0.84 ENST00000317357.10
SOBP
sine oculis binding protein homolog
chr2_+_181891697 0.78 ENST00000431877.7
ITPRID2
ITPR interacting domain containing 2
chr4_+_86934976 0.78 ENST00000507468.5
ENST00000395146.9
AFF1
AF4/FMR2 family member 1
chr2_-_216372432 0.78 ENST00000273067.5
MARCHF4
membrane associated ring-CH-type finger 4
chr8_-_123541197 0.75 ENST00000517956.5
ENST00000443022.2
FBXO32
F-box protein 32
chr7_-_21945866 0.75 ENST00000356195.9
ENST00000447180.5
ENST00000373934.4
ENST00000406877.8
ENST00000457951.5
CDCA7L
cell division cycle associated 7 like
chr15_+_66702219 0.74 ENST00000288840.10
SMAD6
SMAD family member 6
chr18_+_13218769 0.72 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr1_-_235866916 0.70 ENST00000389794.7
LYST
lysosomal trafficking regulator
chr1_+_222618075 0.70 ENST00000344922.10
MIA3
MIA SH3 domain ER export factor 3
chr3_-_125055987 0.69 ENST00000311127.9
HEG1
heart development protein with EGF like domains 1
chrX_+_118974608 0.68 ENST00000304778.11
ENST00000371628.8
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr1_+_61082553 0.68 ENST00000403491.8
ENST00000371187.7
NFIA
nuclear factor I A
chr14_+_57268963 0.67 ENST00000261558.8
AP5M1
adaptor related protein complex 5 subunit mu 1
chr12_+_78864768 0.67 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr5_-_172771187 0.66 ENST00000239223.4
DUSP1
dual specificity phosphatase 1
chr1_+_2228310 0.65 ENST00000378536.5
SKI
SKI proto-oncogene
chr14_-_89619118 0.65 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
FOXN3
forkhead box N3
chr6_-_79947541 0.63 ENST00000369816.5
ELOVL4
ELOVL fatty acid elongase 4
chr17_+_32486975 0.63 ENST00000313401.4
CDK5R1
cyclin dependent kinase 5 regulatory subunit 1
chr21_-_32727933 0.62 ENST00000357345.7
ENST00000429236.5
SYNJ1
synaptojanin 1
chr12_+_64610458 0.62 ENST00000542104.6
RASSF3
Ras association domain family member 3
chr2_+_202634960 0.61 ENST00000392238.3
FAM117B
family with sequence similarity 117 member B
chr13_-_33285682 0.61 ENST00000336934.10
STARD13
StAR related lipid transfer domain containing 13
chr9_-_14693419 0.61 ENST00000380916.9
ZDHHC21
zinc finger DHHC-type palmitoyltransferase 21
chr6_-_111483190 0.61 ENST00000368802.8
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr8_+_37796906 0.61 ENST00000315215.11
ADGRA2
adhesion G protein-coupled receptor A2
chr7_+_1530684 0.60 ENST00000343242.9
MAFK
MAF bZIP transcription factor K
chr12_-_15789375 0.59 ENST00000544064.1
ENST00000642939.1
ENST00000281172.10
ENST00000543523.5
ENST00000644374.1
ENST00000645775.1
ENST00000642278.1
ENST00000646123.1
ENST00000536793.5
EPS8
epidermal growth factor receptor pathway substrate 8
chrX_+_46573757 0.57 ENST00000276055.4
CHST7
carbohydrate sulfotransferase 7
chr6_+_156776020 0.57 ENST00000346085.10
ARID1B
AT-rich interaction domain 1B
chr3_-_129688691 0.57 ENST00000432054.6
TMCC1
transmembrane and coiled-coil domain family 1
chr17_+_49788672 0.57 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
KAT7
lysine acetyltransferase 7
chr5_+_79236092 0.56 ENST00000396137.5
JMY
junction mediating and regulatory protein, p53 cofactor
chr18_+_11981488 0.56 ENST00000269159.8
IMPA2
inositol monophosphatase 2
chr2_+_42048012 0.56 ENST00000294964.6
PKDCC
protein kinase domain containing, cytoplasmic
chr22_+_40177917 0.56 ENST00000454349.7
ENST00000335727.13
TNRC6B
trinucleotide repeat containing adaptor 6B
chr13_-_109786567 0.56 ENST00000375856.5
IRS2
insulin receptor substrate 2
chr1_-_29123886 0.55 ENST00000521452.2
TMEM200B
transmembrane protein 200B
chr18_+_62523002 0.55 ENST00000269499.10
ZCCHC2
zinc finger CCHC-type containing 2
chr14_+_52552830 0.55 ENST00000321662.11
GPR137C
G protein-coupled receptor 137C
chr6_+_70413462 0.54 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
FAM135A
family with sequence similarity 135 member A
chr6_-_52577012 0.54 ENST00000182527.4
TRAM2
translocation associated membrane protein 2
chr9_-_78031775 0.54 ENST00000286548.9
GNAQ
G protein subunit alpha q
chr12_-_7936177 0.54 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr16_+_53054973 0.54 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
CHD9
chromodomain helicase DNA binding protein 9
chr6_-_8064333 0.53 ENST00000543936.7
ENST00000397457.7
BLOC1S5
biogenesis of lysosomal organelles complex 1 subunit 5
chr20_-_32483438 0.53 ENST00000359676.9
NOL4L
nucleolar protein 4 like
chr11_+_73308237 0.53 ENST00000263674.4
ARHGEF17
Rho guanine nucleotide exchange factor 17
chr2_-_208255055 0.52 ENST00000345146.7
IDH1
isocitrate dehydrogenase (NADP(+)) 1
chr9_-_127122623 0.50 ENST00000373417.1
ENST00000373425.8
ANGPTL2
angiopoietin like 2
chr1_-_205680486 0.50 ENST00000367145.4
SLC45A3
solute carrier family 45 member 3
chr5_-_169980474 0.48 ENST00000377365.4
INSYN2B
inhibitory synaptic factor family member 2B
chr10_+_18659382 0.48 ENST00000377275.4
ARL5B
ADP ribosylation factor like GTPase 5B
chr9_-_10612966 0.47 ENST00000381196.9
PTPRD
protein tyrosine phosphatase receptor type D
chr6_+_42782020 0.47 ENST00000314073.9
BICRAL
BRD4 interacting chromatin remodeling complex associated protein like
chr16_+_53434430 0.46 ENST00000262133.11
RBL2
RB transcriptional corepressor like 2
chr1_+_203305510 0.46 ENST00000290551.5
BTG2
BTG anti-proliferation factor 2
chr7_+_94509793 0.44 ENST00000297273.9
CASD1
CAS1 domain containing 1
chr7_+_192561 0.44 ENST00000313766.6
FAM20C
FAM20C golgi associated secretory pathway kinase
chr14_-_39432414 0.44 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr4_-_151226427 0.43 ENST00000304527.8
ENST00000409598.8
SH3D19
SH3 domain containing 19
chr8_-_88327475 0.42 ENST00000286614.11
MMP16
matrix metallopeptidase 16
chr10_+_87863595 0.42 ENST00000371953.8
PTEN
phosphatase and tensin homolog
chr9_+_4490388 0.41 ENST00000262352.8
SLC1A1
solute carrier family 1 member 1
chr6_-_24719146 0.41 ENST00000378119.9
C6orf62
chromosome 6 open reading frame 62
chr9_-_124941054 0.41 ENST00000373555.9
GOLGA1
golgin A1
chr12_+_100573642 0.40 ENST00000266754.9
ENST00000547754.6
GAS2L3
growth arrest specific 2 like 3
chr1_-_221742074 0.40 ENST00000366899.4
DUSP10
dual specificity phosphatase 10
chr14_+_102362931 0.38 ENST00000359520.12
TECPR2
tectonin beta-propeller repeat containing 2
chr4_-_39638846 0.38 ENST00000295958.10
SMIM14
small integral membrane protein 14
chr8_-_65634138 0.37 ENST00000518908.5
ENST00000276569.8
ENST00000519352.1
ARMC1
armadillo repeat containing 1
chr15_-_52678560 0.37 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
FAM214A
family with sequence similarity 214 member A
chr10_-_45535346 0.37 ENST00000453424.7
ENST00000395769.6
MARCHF8
membrane associated ring-CH-type finger 8
chr4_-_110198650 0.37 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chrX_+_77910656 0.36 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr15_+_84817346 0.35 ENST00000258888.6
ALPK3
alpha kinase 3
chr3_+_5187697 0.35 ENST00000256497.9
EDEM1
ER degradation enhancing alpha-mannosidase like protein 1
chrX_+_105822531 0.35 ENST00000243300.14
ENST00000536164.5
NRK
Nik related kinase
chr9_-_136050502 0.34 ENST00000371753.5
NACC2
NACC family member 2
chr19_-_33064872 0.34 ENST00000254260.8
RHPN2
rhophilin Rho GTPase binding protein 2
chr7_-_35695120 0.34 ENST00000311350.8
ENST00000396081.5
HERPUD2
HERPUD family member 2
chr15_-_28322179 0.34 ENST00000261609.13
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr3_-_56468346 0.33 ENST00000288221.11
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr5_+_122775062 0.33 ENST00000379516.7
ENST00000505934.5
ENST00000514949.1
SNX2
sorting nexin 2
chr11_-_2885728 0.32 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
CDKN1C
cyclin dependent kinase inhibitor 1C
chr7_+_76461676 0.32 ENST00000425780.5
ENST00000456590.5
ENST00000451769.5
ENST00000324432.9
ENST00000457529.5
ENST00000446600.5
ENST00000430490.7
ENST00000413936.6
ENST00000423646.5
ENST00000438930.5
DTX2
deltex E3 ubiquitin ligase 2
chr8_-_4994696 0.31 ENST00000400186.7
ENST00000602723.5
CSMD1
CUB and Sushi multiple domains 1
chr4_+_26584064 0.31 ENST00000264866.9
ENST00000505206.5
ENST00000511789.5
TBC1D19
TBC1 domain family member 19
chr6_+_20401864 0.31 ENST00000346618.8
ENST00000613242.4
E2F3
E2F transcription factor 3
chr5_+_58583068 0.30 ENST00000282878.6
RAB3C
RAB3C, member RAS oncogene family
chr1_+_220528112 0.29 ENST00000366917.6
ENST00000402574.5
ENST00000611084.4
ENST00000366918.8
MARK1
microtubule affinity regulating kinase 1
chr1_+_244051275 0.29 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr4_+_158768955 0.29 ENST00000264433.11
FNIP2
folliculin interacting protein 2
chr5_-_78549151 0.28 ENST00000515007.6
LHFPL2
LHFPL tetraspan subfamily member 2
chr3_-_142000353 0.28 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr3_-_115071333 0.28 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chrX_-_77786198 0.28 ENST00000624032.3
ENST00000624668.3
ENST00000373344.11
ENST00000395603.7
ENST00000624166.3
ENST00000623321.3
ENST00000622960.1
ATRX
ATRX chromatin remodeler
chr19_+_48619489 0.28 ENST00000245222.9
SPHK2
sphingosine kinase 2
chr16_+_68023276 0.27 ENST00000567100.5
ENST00000565263.6
ENST00000432752.5
ENST00000569289.5
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr7_+_130070518 0.27 ENST00000335420.10
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr4_-_25862979 0.27 ENST00000399878.8
SEL1L3
SEL1L family member 3
chr11_-_113875555 0.26 ENST00000003302.8
ENST00000545540.5
USP28
ubiquitin specific peptidase 28
chr13_-_98977975 0.25 ENST00000376460.5
DOCK9
dedicator of cytokinesis 9
chr12_-_54419259 0.25 ENST00000293379.9
ITGA5
integrin subunit alpha 5
chr14_+_52730154 0.25 ENST00000354586.5
ENST00000442123.6
STYX
serine/threonine/tyrosine interacting protein
chr17_-_75979117 0.25 ENST00000301608.8
ENST00000293217.10
ENST00000588176.5
ACOX1
acyl-CoA oxidase 1
chr16_-_73048104 0.25 ENST00000268489.10
ZFHX3
zinc finger homeobox 3
chr13_+_108218366 0.25 ENST00000375898.4
ABHD13
abhydrolase domain containing 13
chr9_+_12775012 0.25 ENST00000319264.4
LURAP1L
leucine rich adaptor protein 1 like
chr12_-_104138166 0.25 ENST00000240055.8
NFYB
nuclear transcription factor Y subunit beta
chr14_+_103715724 0.25 ENST00000216602.10
ZFYVE21
zinc finger FYVE-type containing 21
chr3_-_125375249 0.25 ENST00000484491.5
ENST00000492394.5
ENST00000471196.1
ENST00000468369.5
ENST00000485866.5
ENST00000360647.9
ZNF148
zinc finger protein 148
chr4_+_143513661 0.24 ENST00000283131.4
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr7_-_128031422 0.24 ENST00000249363.4
LRRC4
leucine rich repeat containing 4
chr10_-_62816341 0.24 ENST00000242480.4
ENST00000637191.1
EGR2
early growth response 2
chr20_+_41028814 0.24 ENST00000361337.3
TOP1
DNA topoisomerase I
chr20_-_63969890 0.24 ENST00000369888.6
ZNF512B
zinc finger protein 512B
chr2_+_48314637 0.24 ENST00000413569.5
ENST00000340553.8
FOXN2
forkhead box N2
chr5_+_77030360 0.24 ENST00000312916.12
ENST00000506806.1
AGGF1
angiogenic factor with G-patch and FHA domains 1
chr1_-_9910169 0.24 ENST00000377263.6
CTNNBIP1
catenin beta interacting protein 1
chr1_-_153946652 0.24 ENST00000361217.9
DENND4B
DENN domain containing 4B
chr2_+_28392802 0.24 ENST00000379619.5
ENST00000264716.9
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr5_+_103120149 0.23 ENST00000515845.5
ENST00000321521.13
ENST00000507921.5
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr22_-_28679865 0.23 ENST00000397906.6
TTC28
tetratricopeptide repeat domain 28
chrX_-_41922992 0.23 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
CASK
calcium/calmodulin dependent serine protein kinase
chr5_+_119071358 0.23 ENST00000311085.8
DMXL1
Dmx like 1
chr7_-_105388881 0.23 ENST00000460391.5
ENST00000393651.8
SRPK2
SRSF protein kinase 2
chrX_-_24027186 0.23 ENST00000328046.8
KLHL15
kelch like family member 15
chr1_+_213987929 0.23 ENST00000498508.6
ENST00000366958.9
PROX1
prospero homeobox 1
chr1_+_110211471 0.23 ENST00000369787.7
ENST00000413138.7
KCNC4
potassium voltage-gated channel subfamily C member 4
chr11_-_95231046 0.23 ENST00000416495.6
ENST00000536441.7
SESN3
sestrin 3
chr1_+_93079264 0.23 ENST00000370298.9
ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr15_-_42920638 0.23 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
TTBK2
tau tubulin kinase 2
chr10_+_72273914 0.22 ENST00000681898.1
ENST00000307365.4
DDIT4
DNA damage inducible transcript 4
chr1_+_147541491 0.22 ENST00000683836.1
ENST00000234739.8
BCL9
BCL9 transcription coactivator
chr8_-_51899080 0.21 ENST00000360540.9
ENST00000521344.1
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr7_+_77798750 0.21 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
PHTF2
putative homeodomain transcription factor 2
chr1_-_113812448 0.21 ENST00000612242.4
ENST00000261441.9
RSBN1
round spermatid basic protein 1
chr10_-_68527498 0.21 ENST00000609923.6
SLC25A16
solute carrier family 25 member 16
chr19_-_17334844 0.21 ENST00000159087.7
ANO8
anoctamin 8
chr20_-_57710001 0.21 ENST00000341744.8
PMEPA1
prostate transmembrane protein, androgen induced 1
chr2_-_25878445 0.21 ENST00000336112.9
ENST00000435504.9
ASXL2
ASXL transcriptional regulator 2
chr6_+_143450797 0.21 ENST00000367591.5
ENST00000367592.5
PEX3
peroxisomal biogenesis factor 3
chr1_-_70354673 0.20 ENST00000370944.9
ENST00000262346.6
ANKRD13C
ankyrin repeat domain 13C
chr8_+_25184668 0.20 ENST00000276440.12
ENST00000410074.5
DOCK5
dedicator of cytokinesis 5
chr21_+_29298890 0.20 ENST00000286800.8
BACH1
BTB domain and CNC homolog 1
chr18_-_55588184 0.20 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr12_-_42144823 0.20 ENST00000398675.8
GXYLT1
glucoside xylosyltransferase 1
chr14_+_35826298 0.20 ENST00000216807.12
BRMS1L
BRMS1 like transcriptional repressor
chr19_+_16324817 0.20 ENST00000248071.6
ENST00000592003.1
KLF2
Kruppel like factor 2
chr17_-_47189176 0.20 ENST00000531206.5
ENST00000527547.5
ENST00000575483.5
ENST00000066544.8
CDC27
cell division cycle 27
chr6_+_63635792 0.20 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHF3
PHD finger protein 3
chr16_+_28292485 0.20 ENST00000341901.5
SBK1
SH3 domain binding kinase 1
chr12_-_64752871 0.20 ENST00000418919.6
GNS
glucosamine (N-acetyl)-6-sulfatase
chr4_+_150078426 0.20 ENST00000296550.12
DCLK2
doublecortin like kinase 2
chr4_+_98995709 0.19 ENST00000296411.11
ENST00000625963.1
METAP1
methionyl aminopeptidase 1
chr13_-_77327050 0.19 ENST00000684354.1
ENST00000682321.1
ENST00000683823.1
ENST00000683697.1
ENST00000357337.11
ENST00000544440.7
MYCBP2
MYC binding protein 2
chr19_-_409134 0.19 ENST00000332235.8
C2CD4C
C2 calcium dependent domain containing 4C
chr6_+_35213948 0.19 ENST00000274938.8
SCUBE3
signal peptide, CUB domain and EGF like domain containing 3
chr5_-_112419251 0.19 ENST00000261486.6
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr16_+_66880503 0.19 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr9_-_3525968 0.19 ENST00000382004.7
ENST00000617270.5
ENST00000449190.5
RFX3
regulatory factor X3
chr16_+_69565958 0.19 ENST00000349945.7
ENST00000354436.6
NFAT5
nuclear factor of activated T cells 5
chr15_+_79432330 0.19 ENST00000305428.8
MINAR1
membrane integral NOTCH2 associated receptor 1
chr10_+_62804710 0.18 ENST00000373783.3
ADO
2-aminoethanethiol dioxygenase
chrX_-_46759055 0.18 ENST00000328306.4
ENST00000616978.5
SLC9A7
solute carrier family 9 member A7
chr11_-_64803152 0.18 ENST00000439069.5
ENST00000294066.7
ENST00000377350.7
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr11_+_121452291 0.18 ENST00000260197.12
SORL1
sortilin related receptor 1
chr19_-_48363914 0.17 ENST00000377431.6
ENST00000293261.8
TMEM143
transmembrane protein 143
chr4_+_15002443 0.17 ENST00000538197.7
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr1_+_35931076 0.17 ENST00000397828.3
ENST00000373191.9
AGO3
argonaute RISC catalytic component 3
chr7_+_155297776 0.17 ENST00000344756.8
ENST00000425172.1
ENST00000340368.9
ENST00000342407.5
INSIG1
insulin induced gene 1
chr19_+_41219177 0.17 ENST00000301178.9
AXL
AXL receptor tyrosine kinase
chr4_+_112231748 0.17 ENST00000274000.10
ENST00000309703.10
AP1AR
adaptor related protein complex 1 associated regulatory protein
chr21_-_32771712 0.17 ENST00000331923.9
PAXBP1
PAX3 and PAX7 binding protein 1
chr9_-_121201836 0.17 ENST00000373840.9
RAB14
RAB14, member RAS oncogene family
chr8_+_109540075 0.17 ENST00000614147.1
ENST00000337573.10
EBAG9
estrogen receptor binding site associated antigen 9
chr5_+_109689915 0.16 ENST00000261483.5
MAN2A1
mannosidase alpha class 2A member 1
chr14_-_55411817 0.16 ENST00000247178.6
ATG14
autophagy related 14
chr19_-_45160815 0.16 ENST00000317951.6
NKPD1
NTPase KAP family P-loop domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 1.1 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.6 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 1.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 0.9 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.5 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.7 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 0.6 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.1 0.4 GO:0097187 dentinogenesis(GO:0097187)
0.1 1.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 1.0 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 0.5 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.4 GO:0060003 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.4 GO:1903984 rhythmic synaptic transmission(GO:0060024) negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 1.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.6 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.3 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.1 1.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.6 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.1 0.2 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.6 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.9 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:2000798 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.0 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 2.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0060509 Type I pneumocyte differentiation(GO:0060509)
0.0 0.1 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:2000669 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.2 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0019255 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0045820 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 1.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.0 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.0 GO:2001038 positive regulation of female receptivity(GO:0045925) response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) regulation of cellular response to drug(GO:2001038)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.7 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.2 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0000125 PCAF complex(GO:0000125)
0.2 0.9 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 1.0 GO:0016342 catenin complex(GO:0016342)
0.0 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0032116 SMC loading complex(GO:0032116)
0.0 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0033643 host cell part(GO:0033643)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0035276 ethanol binding(GO:0035276)
0.2 1.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.5 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.0 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.5 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.4 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.7 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.0 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.0 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere