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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for BACH2

Z-value: 0.65

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.15 BACH2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg38_v1_chr6_-_90296824_90296851,
hg38_v1_chr6_-_90296908_90296922
-0.331.1e-01Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_102798148 4.67 ENST00000315274.7
matrix metallopeptidase 1
chr15_+_88638947 4.19 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr15_+_88639009 3.52 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr1_-_153549120 3.49 ENST00000368712.1
S100 calcium binding protein A3
chr1_-_153549238 3.23 ENST00000368713.8
S100 calcium binding protein A3
chr4_+_73740541 3.04 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr12_-_104958268 2.87 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr10_-_5977589 1.92 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
interleukin 15 receptor subunit alpha
chr10_-_5977535 1.81 ENST00000379977.8
interleukin 15 receptor subunit alpha
chrX_-_155334580 1.69 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr10_+_102395693 1.62 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr1_+_155135344 1.37 ENST00000484157.5
solute carrier family 50 member 1
chr1_+_156114251 1.27 ENST00000361308.9
lamin A/C
chr6_-_138107412 1.26 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr17_+_81683963 1.25 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr10_-_5977492 1.22 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr8_+_103372388 1.15 ENST00000520337.1
collagen triple helix repeat containing 1
chr1_-_12616762 1.06 ENST00000464917.5
dehydrogenase/reductase 3
chr1_-_6602885 1.04 ENST00000377663.3
kelch like family member 21
chr1_+_156114700 1.01 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chr1_+_156126525 1.00 ENST00000504687.6
ENST00000473598.6
lamin A/C
chr1_-_6602859 0.93 ENST00000377658.8
kelch like family member 21
chr11_-_2929412 0.92 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr6_-_83431038 0.92 ENST00000369705.4
malic enzyme 1
chr18_+_58196736 0.91 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr1_+_36088868 0.89 ENST00000373178.5
ADP-ribosylserine hydrolase
chr16_+_57628684 0.89 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr2_+_68974573 0.82 ENST00000673932.3
ENST00000377938.4
gastrokine 1
chr16_+_57628507 0.80 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr3_+_48466222 0.78 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr18_-_49557 0.76 ENST00000308911.8
tubulin beta 8B
chr6_-_43629222 0.75 ENST00000307126.10
GTP binding protein 2
chr6_+_63571702 0.73 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr17_-_29930062 0.73 ENST00000579954.1
ENST00000269033.7
ENST00000540801.6
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr19_+_38304105 0.72 ENST00000588605.5
ENST00000301246.10
chromosome 19 open reading frame 33
chr22_-_30246739 0.72 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr10_-_25062279 0.70 ENST00000615958.4
enkurin, TRPC channel interacting protein
chr3_+_48465811 0.66 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr11_-_65900375 0.66 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr3_+_11137093 0.66 ENST00000438284.2
histamine receptor H1
chr12_-_70788914 0.65 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr11_-_65662780 0.64 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA proto-oncogene, NF-kB subunit
chr11_-_65900413 0.64 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr7_+_148698857 0.63 ENST00000663835.1
ENST00000655324.1
ENST00000662132.1
ENST00000666124.1
ENST00000325222.9
ENST00000660240.1
cullin 1
chr17_-_58517835 0.63 ENST00000579921.1
ENST00000579925.5
ENST00000323456.9
myotubularin related protein 4
chr1_+_156126160 0.60 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr18_+_34710307 0.59 ENST00000679796.1
dystrobrevin alpha
chr6_+_29942523 0.57 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr7_+_143381286 0.57 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
zyxin
chr5_+_179820895 0.55 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr6_-_35921079 0.54 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chrX_-_49079702 0.53 ENST00000636049.1
ENST00000474053.6
ENST00000635003.1
WD repeat domain 45
chr17_+_4950147 0.53 ENST00000522301.5
enolase 3
chr3_+_184186023 0.52 ENST00000429586.6
ENST00000292808.5
ATP binding cassette subfamily F member 3
chr9_+_100429511 0.52 ENST00000613183.1
Myb/SANT DNA binding domain containing 3
chr12_-_39442943 0.52 ENST00000636569.1
ENST00000541463.6
ENST00000544797.6
ENST00000361418.10
kinesin family member 21A
chr22_+_20507571 0.52 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr6_-_35921128 0.51 ENST00000510290.5
ENST00000423325.6
SRSF protein kinase 1
chr7_-_98869920 0.50 ENST00000345589.4
transmembrane protein 130
chr15_+_86079863 0.49 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr12_+_64452084 0.48 ENST00000677641.1
ENST00000650790.1
ENST00000652657.1
ENST00000676912.1
ENST00000677545.1
ENST00000677632.1
ENST00000331710.10
ENST00000678180.1
ENST00000650762.1
ENST00000676930.1
ENST00000651014.1
ENST00000538890.5
TANK binding kinase 1
chr1_-_109426410 0.48 ENST00000271308.9
proteasome 20S subunit alpha 5
chrX_-_130110679 0.47 ENST00000335997.11
E74 like ETS transcription factor 4
chr11_-_65662931 0.47 ENST00000615805.4
ENST00000612991.4
RELA proto-oncogene, NF-kB subunit
chr3_-_11568764 0.47 ENST00000424529.6
vestigial like family member 4
chr7_-_98870006 0.46 ENST00000339375.9
transmembrane protein 130
chr7_-_945799 0.46 ENST00000611167.4
ArfGAP with dual PH domains 1
chr17_+_21288029 0.45 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr11_-_65382632 0.45 ENST00000294187.10
ENST00000398802.6
ENST00000530936.1
solute carrier family 25 member 45
chr1_+_36155930 0.44 ENST00000316156.8
MAP7 domain containing 1
chr16_-_31150058 0.44 ENST00000569305.1
ENST00000268281.9
ENST00000418068.6
serine protease 36
chr1_+_36156096 0.44 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr17_-_29589536 0.42 ENST00000394869.7
GIT ArfGAP 1
chr6_+_30717433 0.41 ENST00000681435.1
tubulin beta class I
chr22_+_22758698 0.41 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr16_-_1379674 0.41 ENST00000402641.6
ENST00000248104.11
ENST00000674376.1
ENST00000397464.5
unk like zinc finger
chr15_-_80252205 0.41 ENST00000560778.3
cortexin domain containing 1
chr11_+_35618450 0.41 ENST00000317811.6
four-jointed box kinase 1
chrX_-_130110479 0.40 ENST00000308167.10
E74 like ETS transcription factor 4
chr10_+_119651372 0.40 ENST00000369085.8
BAG cochaperone 3
chr15_-_22980334 0.39 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
cytoplasmic FMR1 interacting protein 1
chr19_+_44644025 0.39 ENST00000406449.8
PVR cell adhesion molecule
chr7_-_151024423 0.39 ENST00000469530.4
ENST00000639579.1
autophagy related 9B
chr10_-_30999469 0.39 ENST00000538351.6
zinc finger protein 438
chr17_-_29589606 0.39 ENST00000225394.8
GIT ArfGAP 1
chr12_-_119804298 0.38 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr9_-_111484353 0.38 ENST00000338205.9
ENST00000684092.1
Ecm29 proteasome adaptor and scaffold
chr1_-_27490130 0.38 ENST00000618852.5
WASP family member 2
chr10_+_84328581 0.37 ENST00000359979.8
ENST00000372088.8
coiled-coil serine rich protein 2
chr10_+_84328625 0.37 ENST00000224756.12
coiled-coil serine rich protein 2
chr12_-_119804472 0.37 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chrX_-_49079872 0.36 ENST00000473974.5
ENST00000475880.6
ENST00000634838.1
ENST00000376372.9
ENST00000476728.5
ENST00000635666.1
ENST00000634559.1
ENST00000322995.13
ENST00000634736.1
ENST00000396681.9
ENST00000471338.6
ENST00000485908.6
ENST00000376368.7
ENST00000376358.4
WD repeat domain 45
novel protein
chr2_+_232697362 0.35 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr17_+_75721471 0.35 ENST00000450894.7
integrin subunit beta 4
chr7_-_98869866 0.35 ENST00000416379.6
transmembrane protein 130
chr19_-_4065732 0.34 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr12_-_39443390 0.34 ENST00000361961.7
kinesin family member 21A
chr19_-_35490456 0.33 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chr2_+_88885397 0.33 ENST00000390243.2
immunoglobulin kappa variable 4-1
chrX_-_49043345 0.33 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chr2_-_219308963 0.32 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
protein tyrosine phosphatase receptor type N
chr5_-_176416222 0.32 ENST00000508425.5
clathrin light chain B
chr16_+_30065777 0.31 ENST00000395240.7
ENST00000566846.5
aldolase, fructose-bisphosphate A
chr6_+_12957301 0.31 ENST00000676234.1
phosphatase and actin regulator 1
chr1_+_152908538 0.31 ENST00000368764.4
involucrin
chr12_+_53098846 0.31 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr9_-_35112379 0.31 ENST00000488109.6
family with sequence similarity 214 member B
chr16_+_89921851 0.31 ENST00000554444.5
ENST00000556565.5
tubulin beta 3 class III
chr19_-_10339610 0.31 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr5_-_138575359 0.30 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
heat shock protein family A (Hsp70) member 9
chrX_-_49080066 0.30 ENST00000634944.1
ENST00000423215.3
ENST00000465382.6
WD repeat domain 45
chr3_+_156142962 0.30 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr19_+_49928702 0.30 ENST00000595125.5
activating transcription factor 5
chr16_+_30065753 0.28 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
aldolase, fructose-bisphosphate A
chr5_+_150497772 0.28 ENST00000523767.5
N-deacetylase and N-sulfotransferase 1
chr7_+_134843884 0.28 ENST00000445569.6
caldesmon 1
chr9_+_137241277 0.28 ENST00000340384.5
tubulin beta 4B class IVb
chr22_+_22030934 0.28 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr2_+_219279330 0.28 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr7_+_99408609 0.26 ENST00000403633.6
BUD31 homolog
chr15_+_44537136 0.26 ENST00000261868.10
ENST00000535391.5
eukaryotic translation initiation factor 3 subunit J
chr11_+_64359142 0.26 ENST00000528057.5
ENST00000334205.9
ribosomal protein S6 kinase A4
chr3_-_49358320 0.26 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
glutathione peroxidase 1
chr1_+_19312296 0.26 ENST00000375155.7
ENST00000375153.8
solute carrier family 66 member 1
chr1_-_157138388 0.25 ENST00000368192.9
ETS variant transcription factor 3
chr5_-_176416523 0.25 ENST00000502877.1
ENST00000310418.9
ENST00000345807.7
clathrin light chain B
chr18_+_34710249 0.25 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr3_-_49358272 0.25 ENST00000419349.2
glutathione peroxidase 1
chr8_-_30658176 0.25 ENST00000355904.9
general transcription factor IIE subunit 2
chr11_-_65381951 0.24 ENST00000526432.5
ENST00000527174.5
solute carrier family 25 member 45
chr17_+_75721327 0.24 ENST00000579662.5
integrin subunit beta 4
chr1_+_19312341 0.24 ENST00000400548.6
solute carrier family 66 member 1
chr20_-_1329131 0.23 ENST00000360779.4
syndecan binding protein 2
chr9_+_4985227 0.23 ENST00000381652.4
Janus kinase 2
chr2_-_218993401 0.22 ENST00000453769.1
ENST00000392096.6
ENST00000295728.7
crystallin beta A2
chr11_+_10456186 0.22 ENST00000528723.5
adenosine monophosphate deaminase 3
chr15_-_34795541 0.21 ENST00000290378.6
actin alpha cardiac muscle 1
chr11_-_64246190 0.21 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr17_-_40755328 0.21 ENST00000312150.5
keratin 25
chr22_+_22395005 0.20 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr22_+_22322452 0.20 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr15_+_44537085 0.19 ENST00000424492.7
eukaryotic translation initiation factor 3 subunit J
chr3_-_49786194 0.18 ENST00000613416.4
inositol hexakisphosphate kinase 1
chr20_+_45406560 0.18 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr1_-_153985366 0.18 ENST00000614713.4
RAB13, member RAS oncogene family
chr17_-_7687427 0.18 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
tumor protein p53
chr22_+_22734577 0.17 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr3_+_191329020 0.17 ENST00000392456.4
coiled-coil domain containing 50
chr20_-_37178966 0.17 ENST00000422138.1
maestro heat like repeat family member 8
chr3_-_9878488 0.17 ENST00000443115.1
cell death inducing DFFA like effector c
chr11_-_64245816 0.17 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr22_+_39520553 0.17 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr8_-_26867267 0.16 ENST00000380573.4
adrenoceptor alpha 1A
chr19_-_45782388 0.16 ENST00000458663.6
DM1 protein kinase
chr6_-_30717264 0.16 ENST00000376406.8
mediator of DNA damage checkpoint 1
chr5_+_148203024 0.15 ENST00000325630.3
serine peptidase inhibitor Kazal type 6
chr17_-_41140487 0.15 ENST00000345847.4
keratin associated protein 4-6
chr19_-_15815664 0.15 ENST00000641419.1
olfactory receptor family 10 subfamily H member 1
chr1_-_107688492 0.15 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chr3_-_48595267 0.15 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr17_+_57085092 0.14 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr3_-_49786508 0.14 ENST00000395238.5
ENST00000468463.5
ENST00000321599.9
ENST00000460540.1
inositol hexakisphosphate kinase 1
chr1_-_207051202 0.14 ENST00000315927.9
YOD1 deubiquitinase
chr11_+_64924673 0.14 ENST00000164133.7
ENST00000532850.1
protein phosphatase 2 regulatory subunit B'beta
chr1_+_26280117 0.14 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr17_-_35063648 0.13 ENST00000394597.7
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr3_+_191329342 0.13 ENST00000392455.9
coiled-coil domain containing 50
chr11_-_66336396 0.13 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr12_+_56338873 0.13 ENST00000228534.6
interleukin 23 subunit alpha
chrX_+_41333905 0.13 ENST00000457138.7
ENST00000643821.1
DEAD-box helicase 3 X-linked
chr1_-_157138474 0.12 ENST00000326786.4
ETS variant transcription factor 3
chr17_+_7219857 0.12 ENST00000583312.5
ENST00000350303.9
ENST00000584103.5
ENST00000356839.10
ENST00000579886.2
acyl-CoA dehydrogenase very long chain
chr1_-_115338231 0.12 ENST00000369512.3
ENST00000680116.1
ENST00000681124.1
ENST00000675637.2
ENST00000676038.2
nerve growth factor
chr3_-_46566276 0.12 ENST00000395905.8
leucine rich repeat containing 2
chr17_-_49210567 0.11 ENST00000507680.6
G protein subunit gamma transducin 2
chr4_+_70195719 0.11 ENST00000683306.1
odontogenic, ameloblast associated
chr3_+_184299198 0.11 ENST00000417952.5
ENST00000310118.9
proteasome 26S subunit, non-ATPase 2
chr1_+_150508074 0.11 ENST00000369049.8
extracellular matrix protein 1
chr5_+_148202771 0.10 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr1_+_150508099 0.10 ENST00000346569.6
ENST00000369047.9
extracellular matrix protein 1
chr12_-_8066331 0.10 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr12_-_57478070 0.10 ENST00000549602.1
ENST00000430041.6
Rho GTPase activating protein 9
chr6_+_12957347 0.10 ENST00000482982.2
phosphatase and actin regulator 1
chr17_-_67366562 0.10 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chr15_+_68930570 0.10 ENST00000455873.7
NADPH oxidase 5
chr3_-_120682215 0.10 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr17_-_50707855 0.09 ENST00000285243.7
ankyrin repeat domain 40
chr22_+_22357739 0.09 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr7_+_150368189 0.09 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr17_-_44268119 0.09 ENST00000399246.3
ENST00000262418.12
solute carrier family 4 member 1 (Diego blood group)
chr2_-_11466156 0.08 ENST00000381525.8
ENST00000307236.8
ENST00000542100.5
ENST00000546212.2
E2F transcription factor 6
chr17_-_61591192 0.08 ENST00000521764.3
nascent polypeptide associated complex subunit alpha 2
chr2_-_11344580 0.08 ENST00000616279.4
ENST00000315872.11
Rho associated coiled-coil containing protein kinase 2
chr12_-_55728994 0.08 ENST00000257857.9
CD63 molecule
chr17_-_75154534 0.08 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr19_-_55370455 0.08 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr9_-_124415421 0.08 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr1_+_203127678 0.08 ENST00000640524.1
ENST00000337894.9
adenosine A1 receptor
chr1_-_211675557 0.07 ENST00000366998.4
ENST00000366999.9
ENST00000540251.5
NIMA related kinase 2
chr22_+_22327298 0.07 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 3.9 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.5 1.4 GO:0042946 glucoside transport(GO:0042946)
0.4 1.6 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 1.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.3 0.9 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.3 3.0 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.2 0.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.2 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.5 GO:1902905 positive regulation of fibril organization(GO:1902905)
0.2 1.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 2.9 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.9 GO:1902031 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.1 0.3 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 0.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 1.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.3 GO:0002934 desmosome organization(GO:0002934)
0.1 1.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 4.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.7 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 0.5 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 1.3 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.5 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.6 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310) regulation of mRNA modification(GO:0090365)
0.0 1.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.5 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.4 1.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.4 1.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.4 3.9 GO:0005638 lamin filament(GO:0005638)
0.2 2.0 GO:0005827 polar microtubule(GO:0005827)
0.2 1.7 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 0.6 GO:0044753 amphisome(GO:0044753)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 7.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0097413 Lewy body(GO:0097413)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.5 1.4 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.2 1.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 3.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.9 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 3.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 4.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 9.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 2.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 8.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha