Project
Inflammatory response time course, HUVEC (Wada, 2009)
Navigation
Downloads
Results for BPTF
Z-value: 1.70
Motif logo
Transcription factors associated with BPTF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BPTF | hg38_v1_chr17_+_67825494_67825528 | 0.66 | 3.1e-04 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BPTF
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.0 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 0.4 | 15.8 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 12.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 8.9 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 1.4 | 8.4 | GO:0061518 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) |
| 0.7 | 7.7 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.4 | 5.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.9 | 5.4 | GO:0051585 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.6 | 4.9 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 1.2 | 4.8 | GO:1904835 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.5 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 15.5 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 10.3 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.3 | 10.1 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 8.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.3 | 7.7 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 6.7 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.2 | 6.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 6.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.2 | 5.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 18.3 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.5 | 14.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 9.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 7.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 7.0 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.9 | 5.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 1.0 | 4.9 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.0 | 4.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 1.5 | 4.6 | GO:0046577 | long-chain-alcohol oxidase activity(GO:0046577) |
| 0.4 | 4.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.2 | 12.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 11.0 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 8.8 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 6.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.3 | 5.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 4.7 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 3.4 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 3.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 3.1 | PID TRAIL PATHWAY | TRAIL signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 21.1 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 8.9 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.2 | 7.8 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.2 | 6.4 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 5.2 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 5.2 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.3 | 4.8 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 3.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 3.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 3.5 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |