Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for CBFB

Z-value: 0.38

Motif logo

logo of

Transcription factors associated with CBFB

Gene Symbol Gene ID Gene Info
CBFB
ENSG00000067955.15 CBFB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CBFBhg38_v1_chr16_+_67029133_670291850.203.4e-01Click!

Activity profile of CBFB motif

Sorted Z-values of CBFB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CBFB

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_132073782 1.47 ENST00000296871.4
CSF2
colony stimulating factor 2
chr5_+_35856883 1.14 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr2_+_102418642 0.75 ENST00000264260.6
IL18RAP
interleukin 18 receptor accessory protein
chr21_-_35049238 0.71 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX1
RUNX family transcription factor 1
chr8_+_103372388 0.70 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr21_-_35049327 0.70 ENST00000300305.7
RUNX1
RUNX family transcription factor 1
chrX_+_68829009 0.65 ENST00000204961.5
EFNB1
ephrin B1
chr9_-_127778659 0.57 ENST00000314830.13
SH2D3C
SH2 domain containing 3C
chr3_-_190122317 0.40 ENST00000427335.6
P3H2
prolyl 3-hydroxylase 2
chr8_-_133060347 0.36 ENST00000427060.6
SLA
Src like adaptor
chr12_+_14973020 0.34 ENST00000266395.3
PDE6H
phosphodiesterase 6H
chr18_-_28177934 0.29 ENST00000676445.1
CDH2
cadherin 2
chr13_-_28100556 0.28 ENST00000241453.12
FLT3
fms related receptor tyrosine kinase 3
chr11_-_58575846 0.23 ENST00000395074.7
LPXN
leupaxin
chr6_-_75202792 0.23 ENST00000416123.6
COL12A1
collagen type XII alpha 1 chain
chr14_-_60649449 0.23 ENST00000645694.3
SIX1
SIX homeobox 1
chr8_-_95269190 0.22 ENST00000286688.6
C8orf37
chromosome 8 open reading frame 37
chr17_+_66302606 0.22 ENST00000413366.8
PRKCA
protein kinase C alpha
chr7_+_120988683 0.21 ENST00000340646.9
ENST00000310396.10
CPED1
cadherin like and PC-esterase domain containing 1
chr11_-_16356538 0.21 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chr17_+_34255274 0.20 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr6_+_27957241 0.20 ENST00000244623.1
OR2B6
olfactory receptor family 2 subfamily B member 6
chr2_-_218985176 0.20 ENST00000295727.2
FEV
FEV transcription factor, ETS family member
chr1_+_209686173 0.18 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
chr4_+_73481737 0.17 ENST00000226355.5
AFM
afamin
chr4_+_87975667 0.16 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
SPP1
secreted phosphoprotein 1
chr17_-_65560296 0.16 ENST00000585045.1
ENST00000611991.1
AXIN2
axin 2
chr4_+_87975829 0.15 ENST00000614857.5
SPP1
secreted phosphoprotein 1
chr11_-_65117639 0.14 ENST00000528598.1
ENST00000310597.6
ZNHIT2
zinc finger HIT-type containing 2
chr1_-_11796536 0.14 ENST00000641820.1
MTHFR
methylenetetrahydrofolate reductase
chr15_+_73684204 0.14 ENST00000537340.6
ENST00000318424.9
CD276
CD276 molecule
chr3_+_133124807 0.13 ENST00000508711.5
TMEM108
transmembrane protein 108
chr2_-_127220293 0.13 ENST00000664447.2
ENST00000409327.2
CYP27C1
cytochrome P450 family 27 subfamily C member 1
chr3_-_11568764 0.13 ENST00000424529.6
VGLL4
vestigial like family member 4
chr19_-_13937991 0.13 ENST00000254320.7
ENST00000586075.1
PODNL1
podocan like 1
chr3_+_157436842 0.12 ENST00000295927.4
PTX3
pentraxin 3
chr1_-_184037695 0.11 ENST00000361927.9
ENST00000649786.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr15_+_49423233 0.11 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
FGF7
fibroblast growth factor 7
chr9_+_15422704 0.11 ENST00000380821.7
ENST00000610884.4
ENST00000421710.5
SNAPC3
small nuclear RNA activating complex polypeptide 3
chr19_-_13938371 0.11 ENST00000588872.3
ENST00000339560.10
PODNL1
podocan like 1
chr14_-_59484317 0.11 ENST00000247194.9
L3HYPDH
trans-L-3-hydroxyproline dehydratase
chr22_+_31082860 0.10 ENST00000619644.4
SMTN
smoothelin
chr20_+_46008900 0.10 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chrX_-_49184789 0.10 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr4_-_155376797 0.10 ENST00000650955.1
ENST00000515654.5
MAP9
microtubule associated protein 9
chr12_-_53200443 0.09 ENST00000550743.6
ITGB7
integrin subunit beta 7
chr14_-_59484006 0.09 ENST00000481608.1
L3HYPDH
trans-L-3-hydroxyproline dehydratase
chr11_-_66336396 0.09 ENST00000627248.1
ENST00000311320.9
RIN1
Ras and Rab interactor 1
chr1_+_17308194 0.06 ENST00000375453.5
ENST00000375448.4
PADI4
peptidyl arginine deiminase 4
chr12_+_80716906 0.06 ENST00000228644.4
MYF5
myogenic factor 5
chr10_-_46023445 0.06 ENST00000585132.5
NCOA4
nuclear receptor coactivator 4
chr2_-_206159194 0.06 ENST00000455934.6
ENST00000449699.5
ENST00000454195.1
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr4_+_70226116 0.06 ENST00000317987.6
FDCSP
follicular dendritic cell secreted protein
chr13_-_46182136 0.05 ENST00000323076.7
LCP1
lymphocyte cytosolic protein 1
chr12_-_54634880 0.05 ENST00000547511.5
ENST00000257867.5
LACRT
lacritin
chr18_+_13611910 0.04 ENST00000590308.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr19_+_10430786 0.04 ENST00000293683.9
PDE4A
phosphodiesterase 4A
chr15_+_73683938 0.04 ENST00000567189.5
CD276
CD276 molecule
chr2_-_206159410 0.03 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr1_-_206772484 0.03 ENST00000423557.1
IL10
interleukin 10
chr12_-_54384687 0.03 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
ZNF385A
zinc finger protein 385A
chr7_+_100969565 0.02 ENST00000536621.6
ENST00000379442.7
MUC12
mucin 12, cell surface associated
chr2_-_87021844 0.02 ENST00000355705.4
ENST00000409310.6
PLGLB1
plasminogen like B1
chr5_+_132060648 0.02 ENST00000296870.3
IL3
interleukin 3
chr6_+_52186373 0.02 ENST00000648244.1
IL17A
interleukin 17A
chr1_-_184754808 0.02 ENST00000318130.13
ENST00000367512.7
EDEM3
ER degradation enhancing alpha-mannosidase like protein 3
chr5_-_39202991 0.02 ENST00000515010.5
FYB1
FYN binding protein 1
chr20_+_56412112 0.00 ENST00000360314.7
CASS4
Cas scaffold protein family member 4
chr1_+_34176900 0.00 ENST00000488417.2
C1orf94
chromosome 1 open reading frame 94
chr16_+_53054973 0.00 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_120876356 0.00 ENST00000456291.1
PHF19
PHD finger protein 19

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 1.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.7 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.2 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.2 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine