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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for CDC5L

Z-value: 0.90

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Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
ENSG00000096401.8 CDC5L

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg38_v1_chr6_+_44387686_443877300.183.9e-01Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_73740541 4.00 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr15_+_62066975 3.38 ENST00000355522.5
C2 calcium dependent domain containing 4A
chr2_+_102104563 3.36 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr14_+_21990357 2.85 ENST00000390444.1
T cell receptor alpha variable 16
chr2_+_227813834 2.57 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr21_+_42199686 2.57 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr7_-_22194709 2.39 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr5_+_119354771 2.25 ENST00000503646.1
TNF alpha induced protein 8
chr2_+_230759918 2.23 ENST00000614925.1
calcium binding protein 39
chr1_-_120054225 2.20 ENST00000602566.6
notch receptor 2
chr11_-_102780620 1.78 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr14_+_22070548 1.57 ENST00000390450.3
T cell receptor alpha variable 22
chr7_+_134745460 1.50 ENST00000436461.6
caldesmon 1
chr18_+_63887698 1.50 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr15_-_55270383 1.46 ENST00000396307.6
RAB27A, member RAS oncogene family
chr2_-_224947030 1.34 ENST00000409592.7
dedicator of cytokinesis 10
chr15_-_55270280 1.31 ENST00000564609.5
RAB27A, member RAS oncogene family
chr6_+_36029082 1.30 ENST00000472333.1
mitogen-activated protein kinase 14
chr5_+_141421064 1.27 ENST00000518882.2
protocadherin gamma subfamily A, 11
chr3_-_127822455 1.17 ENST00000265052.10
monoglyceride lipase
chr1_-_85404494 1.16 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr4_-_158159657 1.15 ENST00000590648.5
golgi associated kinase 1B
chr2_-_174847765 1.13 ENST00000443238.6
chimerin 1
chr8_+_103298433 1.12 ENST00000522566.5
frizzled class receptor 6
chr15_-_58279245 1.09 ENST00000558231.5
aldehyde dehydrogenase 1 family member A2
chr2_+_161231078 1.02 ENST00000439442.1
TRAF family member associated NFKB activator
chr5_-_134174765 1.01 ENST00000520417.1
S-phase kinase associated protein 1
chr6_+_32844789 1.00 ENST00000414474.5
proteasome 20S subunit beta 9
chr12_-_9760893 0.98 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr1_-_89126066 0.97 ENST00000370466.4
guanylate binding protein 2
chr17_-_7590072 0.96 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SRY-box transcription factor 15
chr13_-_40982880 0.96 ENST00000635415.1
E74 like ETS transcription factor 1
chr7_+_134866831 0.90 ENST00000435928.1
caldesmon 1
chr6_+_127577168 0.85 ENST00000329722.8
chromosome 6 open reading frame 58
chr5_-_147401591 0.83 ENST00000520473.1
dihydropyrimidinase like 3
chr11_+_20022550 0.78 ENST00000533917.5
neuron navigator 2
chr8_+_103298836 0.78 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr5_-_16916400 0.77 ENST00000513882.5
myosin X
chr15_-_55319107 0.76 ENST00000565225.1
ENST00000436697.3
ENST00000567948.1
ENST00000563262.5
PIGB opposite strand 1
RAB27A, member RAS oncogene family
chr7_-_122699108 0.76 ENST00000340112.3
ring finger protein 133
chr12_-_39340963 0.75 ENST00000552961.5
kinesin family member 21A
chr1_-_220089818 0.71 ENST00000498791.6
ENST00000480959.6
3'(2'), 5'-bisphosphate nucleotidase 1
chr4_+_2418932 0.71 ENST00000635017.1
cilia and flagella associated protein 99
chr20_-_31951970 0.71 ENST00000202017.6
p53 and DNA damage regulated 1
chr17_-_4739866 0.69 ENST00000574412.6
ENST00000293778.12
C-X-C motif chemokine ligand 16
chr18_+_58341038 0.69 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr18_-_12656716 0.69 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr1_-_85578345 0.68 ENST00000426972.8
dimethylarginine dimethylaminohydrolase 1
chr2_+_165239388 0.68 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr12_-_57772087 0.68 ENST00000324871.12
ENST00000257848.7
methyltransferase like 1
chr12_-_55842950 0.67 ENST00000548629.5
matrix metallopeptidase 19
chr6_+_144583198 0.67 ENST00000367526.8
utrophin
chr17_+_58238426 0.67 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr16_+_1678304 0.66 ENST00000569765.5
Jupiter microtubule associated homolog 2
chr7_-_14841267 0.66 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr5_+_55024250 0.64 ENST00000231009.3
granzyme K
chr11_-_13496018 0.64 ENST00000529816.1
parathyroid hormone
chr2_+_27537380 0.62 ENST00000447166.2
chromosome 2 open reading frame 16
chr10_+_84452208 0.61 ENST00000480006.1
coiled-coil serine rich protein 2
chr3_-_197260369 0.61 ENST00000658155.1
ENST00000453607.5
discs large MAGUK scaffold protein 1
chr6_+_108656346 0.60 ENST00000540898.1
forkhead box O3
chr4_+_154563003 0.59 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr13_+_31739520 0.58 ENST00000298386.7
relaxin family peptide receptor 2
chr13_+_31739542 0.58 ENST00000380314.2
relaxin family peptide receptor 2
chr1_-_150765735 0.58 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr12_+_77830886 0.58 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr3_-_71493500 0.57 ENST00000648380.1
ENST00000650295.1
forkhead box P1
chr15_+_70936487 0.57 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr5_+_141421020 0.57 ENST00000622044.1
ENST00000398587.7
protocadherin gamma subfamily A, 11
chr6_-_131701401 0.56 ENST00000315453.4
olfactory receptor family 2 subfamily A member 4
chr7_+_128758947 0.56 ENST00000493278.1
calumenin
chr20_-_18497218 0.55 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr10_-_114526804 0.55 ENST00000369266.7
ENST00000369253.6
actin binding LIM protein 1
chr18_+_58221535 0.54 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr5_+_141364153 0.54 ENST00000518069.2
protocadherin gamma subfamily A, 5
chr8_-_86230360 0.54 ENST00000419776.2
ENST00000297524.8
solute carrier family 7 member 13
chr12_-_91153149 0.53 ENST00000550758.1
decorin
chr5_-_177780633 0.53 ENST00000513554.5
ENST00000440605.7
family with sequence similarity 153 member A
chr10_+_124942123 0.52 ENST00000359653.4
zinc finger RANBP2-type containing 1
chr5_-_157859096 0.52 ENST00000530742.5
ENST00000523908.5
ENST00000523094.5
ENST00000411809.7
clathrin interactor 1
chr7_+_116524984 0.51 ENST00000614113.5
ENST00000393470.1
caveolin 1
chrX_-_69165509 0.51 ENST00000361478.1
praja ring finger ubiquitin ligase 1
chr5_+_121961955 0.51 ENST00000339397.5
serum response factor binding protein 1
chr18_+_79400274 0.50 ENST00000545796.5
ENST00000318065.9
ENST00000592223.5
ENST00000329101.8
ENST00000586434.1
nuclear factor of activated T cells 1
chr6_+_113857333 0.50 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr3_+_172754457 0.50 ENST00000441497.6
epithelial cell transforming 2
chr1_-_204166334 0.49 ENST00000272190.9
renin
chr8_-_100950549 0.49 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr1_-_181022842 0.48 ENST00000258301.6
syntaxin 6
chr6_+_110874775 0.48 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr2_-_162536955 0.48 ENST00000621889.1
potassium voltage-gated channel subfamily H member 7
chr5_+_70025247 0.47 ENST00000380751.9
ENST00000380750.8
ENST00000503931.5
ENST00000506542.1
small EDRK-rich factor 1B
chr6_-_29457071 0.47 ENST00000377149.5
olfactory receptor family 11 subfamily A member 1
chr3_-_108953762 0.46 ENST00000393963.7
ENST00000471108.1
guanylate cyclase activator 1C
chr2_+_169069537 0.45 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr5_+_141359970 0.45 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr9_+_12775012 0.45 ENST00000319264.4
leucine rich adaptor protein 1 like
chr2_+_165239432 0.45 ENST00000636071.2
ENST00000636985.2
sodium voltage-gated channel alpha subunit 2
chrM_+_12329 0.45 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr9_+_102995308 0.44 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr6_-_136525961 0.43 ENST00000438100.6
microtubule associated protein 7
chr15_-_55917080 0.43 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr16_-_19886133 0.43 ENST00000568214.1
ENST00000569479.5
G protein-coupled receptor class C group 5 member B
chr11_-_62841809 0.43 ENST00000525239.5
ENST00000538098.2
WD repeat domain 74
chrX_-_69165430 0.42 ENST00000374584.3
ENST00000590146.1
ENST00000374571.5
praja ring finger ubiquitin ligase 1
chr22_-_35961623 0.41 ENST00000408983.2
RNA binding fox-1 homolog 2
chr9_-_133348022 0.41 ENST00000446777.5
ENST00000610888.4
ENST00000371999.5
ENST00000494177.6
ENST00000343730.10
ENST00000457204.2
mediator complex subunit 22
chr10_+_113129285 0.41 ENST00000637574.1
transcription factor 7 like 2
chr4_+_99574812 0.41 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr3_-_119677346 0.41 ENST00000484810.5
ENST00000497116.1
ENST00000261070.7
cytochrome c oxidase copper chaperone COX17
chr10_-_72354895 0.41 ENST00000444643.8
ENST00000338820.7
ENST00000394903.6
DnaJ heat shock protein family (Hsp40) member B12
chr6_-_17706748 0.41 ENST00000613258.4
ENST00000537253.5
nucleoporin 153
chr10_+_27504328 0.41 ENST00000375802.7
RAB18, member RAS oncogene family
chr16_+_1678271 0.41 ENST00000562684.5
ENST00000561516.5
ENST00000248098.8
ENST00000382711.9
ENST00000566742.5
Jupiter microtubule associated homolog 2
chr4_+_69931066 0.41 ENST00000246891.9
casein alpha s1
chr3_-_57292676 0.41 ENST00000389601.3
ENST00000487349.6
ankyrin repeat and SOCS box containing 14
chr4_-_99352730 0.40 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr3_-_99850976 0.40 ENST00000487087.5
filamin A interacting protein 1 like
chrX_+_103776831 0.40 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chr10_+_94762673 0.40 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr7_+_29479712 0.39 ENST00000412711.6
chimerin 2
chr11_-_47426419 0.39 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr3_-_119559599 0.39 ENST00000264246.8
CD80 molecule
chr6_-_17706852 0.39 ENST00000262077.3
nucleoporin 153
chrX_-_135764444 0.39 ENST00000597510.6
cancer/testis antigen family 45 member A3
chr12_+_50400809 0.38 ENST00000293618.12
ENST00000429001.7
ENST00000398473.7
ENST00000548174.5
ENST00000548697.5
ENST00000548993.5
ENST00000614335.4
ENST00000522085.5
ENST00000615080.4
ENST00000518444.5
ENST00000551886.5
ENST00000523389.5
ENST00000518561.5
ENST00000347328.9
ENST00000550260.1
La ribonucleoprotein 4
chr19_+_3880647 0.38 ENST00000450849.7
ATCAY kinesin light chain interacting caytaxin
chr13_+_23180960 0.38 ENST00000218867.4
sarcoglycan gamma
chr13_-_98977975 0.38 ENST00000376460.5
dedicator of cytokinesis 9
chr17_-_676348 0.37 ENST00000681510.1
ENST00000679680.1
VPS53 subunit of GARP complex
chr8_+_76683779 0.37 ENST00000523885.2
zinc finger homeobox 4
chr9_-_21368962 0.37 ENST00000610660.1
interferon alpha 13
chr12_-_70788914 0.37 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr14_-_23551729 0.37 ENST00000419474.5
zinc finger homeobox 2
chr10_+_27532521 0.37 ENST00000683924.1
RAB18, member RAS oncogene family
chr10_-_67838173 0.36 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr4_-_158173042 0.36 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr8_-_115492221 0.36 ENST00000518018.1
transcriptional repressor GATA binding 1
chr15_-_55917129 0.36 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr3_-_197260722 0.36 ENST00000654733.1
ENST00000661808.1
discs large MAGUK scaffold protein 1
chr16_-_29923237 0.36 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr10_-_104338431 0.35 ENST00000647721.1
ENST00000337478.3
inositol 1,4,5-trisphosphate receptor interacting protein
chr3_+_109136707 0.35 ENST00000622536.6
chromosome 3 open reading frame 85
chr1_-_154627945 0.35 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr4_+_145625992 0.35 ENST00000541599.5
metabolism of cobalamin associated A
chr3_+_33277433 0.35 ENST00000484457.6
ENST00000538892.5
F-box and leucine rich repeat protein 2
chr5_+_167754918 0.35 ENST00000519204.5
teneurin transmembrane protein 2
chr11_-_47426216 0.35 ENST00000530651.5
ENST00000524447.6
ENST00000531051.6
ENST00000526993.1
ENST00000602866.5
proteasome 26S subunit, ATPase 3
chr8_+_11809135 0.35 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr12_-_108561294 0.35 ENST00000546611.1
spliceosome associated factor 3, U4/U6 recycling protein
chr8_+_22053543 0.34 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr9_-_125650417 0.34 ENST00000420643.5
MAPK associated protein 1
chr11_-_13495984 0.33 ENST00000282091.6
parathyroid hormone
chr2_+_209653171 0.33 ENST00000447185.5
microtubule associated protein 2
chr12_+_18242955 0.33 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr13_-_98978022 0.33 ENST00000682017.1
ENST00000442173.5
ENST00000627024.2
dedicator of cytokinesis 9
chrX_+_11111291 0.32 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
holocytochrome c synthase
chr12_+_10179006 0.32 ENST00000298530.7
transmembrane protein 52B
chr4_-_122456725 0.32 ENST00000226730.5
interleukin 2
chr6_-_49636832 0.32 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chr5_-_111758061 0.32 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chrX_+_100584928 0.32 ENST00000373031.5
tenomodulin
chr19_-_11435098 0.32 ENST00000356392.9
ENST00000591179.5
outer dynein arm docking complex subunit 3
chr8_+_66021545 0.32 ENST00000276570.10
DnaJ heat shock protein family (Hsp40) member C5 beta
chr6_-_28443463 0.32 ENST00000289788.4
zinc finger and SCAN domain containing 23
chr5_+_141412979 0.32 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr17_-_41041447 0.32 ENST00000306271.5
keratin associated protein 1-1
chr12_+_18261511 0.32 ENST00000538779.6
ENST00000433979.6
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chrX_+_10158448 0.32 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr11_-_101129806 0.31 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr17_+_59940908 0.31 ENST00000591035.1
novel protein
chr5_-_32174262 0.31 ENST00000265070.7
golgi phosphoprotein 3
chr6_-_136526472 0.31 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr11_-_101129706 0.31 ENST00000534013.5
progesterone receptor
chr1_-_226739271 0.30 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr20_-_50113139 0.30 ENST00000371657.9
ENST00000371674.8
ENST00000625172.3
ENST00000557021.5
ENST00000617119.4
ubiquitin conjugating enzyme E2 V1
chr2_+_70087468 0.30 ENST00000303577.7
poly(rC) binding protein 1
chr15_+_41286011 0.30 ENST00000661438.1
novel protein
chr16_-_18896874 0.30 ENST00000565324.5
ENST00000561947.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr12_-_91179472 0.29 ENST00000550099.5
ENST00000546391.5
decorin
chr4_-_167234579 0.29 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr6_-_27872334 0.29 ENST00000616365.2
H3 clustered histone 11
chr10_-_67838019 0.29 ENST00000483798.6
DnaJ heat shock protein family (Hsp40) member C12
chr1_+_156369202 0.29 ENST00000537040.6
Rh family B glycoprotein
chr10_+_110005804 0.29 ENST00000360162.7
adducin 3
chr3_+_100635598 0.28 ENST00000475887.1
adhesion G protein-coupled receptor G7
chrX_-_15664798 0.28 ENST00000380342.4
collectrin, amino acid transport regulator
chr12_+_10179024 0.28 ENST00000543484.2
transmembrane protein 52B
chr12_-_57078784 0.28 ENST00000300128.9
nuclear envelope integral membrane protein 1
chr10_-_92497727 0.28 ENST00000496903.5
ENST00000678824.1
ENST00000371581.9
insulin degrading enzyme
chr17_+_47831608 0.28 ENST00000269025.9
leucine rich repeat containing 46
chr3_+_46370854 0.28 ENST00000292303.4
C-C motif chemokine receptor 5
chr4_-_167234426 0.28 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr9_-_21166660 0.28 ENST00000380225.1
interferon alpha 21
chr14_+_66824439 0.27 ENST00000555456.1
gephyrin
chr7_-_113919000 0.27 ENST00000284601.4
protein phosphatase 1 regulatory subunit 3A
chr3_-_155676363 0.27 ENST00000494598.5
phospholipase C eta 1
chr8_+_90940517 0.27 ENST00000521366.1
N-terminal EF-hand calcium binding protein 1
chr3_+_63443306 0.27 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr1_-_244862381 0.26 ENST00000640001.1
ENST00000639628.1
heterogeneous nuclear ribonucleoprotein U

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.9 2.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9 2.6 GO:0009720 detection of hormone stimulus(GO:0009720)
0.6 3.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.6 2.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.5 1.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.4 4.8 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.3 1.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.3 0.8 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.3 0.8 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.2 1.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 1.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.2 3.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.6 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 1.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 1.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.8 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.6 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.0 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.5 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 1.8 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.3 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.3 GO:0090164 protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.2 GO:1903823 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.2 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542) luteolysis(GO:0001554)
0.1 1.1 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.3 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 3.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.0 0.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 1.2 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.0 1.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.6 GO:0036301 interleukin-21 production(GO:0032625) macrophage colony-stimulating factor production(GO:0036301) interleukin-21 secretion(GO:0072619) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0033563 spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 2.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.0 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 2.6 GO:0030478 actin cap(GO:0030478)
0.2 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.4 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 1.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 2.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:0097462 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 0.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.0 0.6 GO:0090543 Flemming body(GO:0090543)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.8 3.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6 2.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 4.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 2.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 1.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 2.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 3.2 GO:0031489 myosin V binding(GO:0031489)
0.1 0.8 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.3 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 1.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.1 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.2 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 2.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 2.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 1.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.5 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0052723 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 1.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 7.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 4.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 4.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.8 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.7 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)