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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for CDX2

Z-value: 0.82

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Transcription factors associated with CDX2

Gene Symbol Gene ID Gene Info
ENSG00000165556.10 CDX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX2hg38_v1_chr13_-_27969295_279693500.038.7e-01Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_32844789 4.52 ENST00000414474.5
proteasome 20S subunit beta 9
chr4_-_76023489 4.11 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr1_-_7940825 2.49 ENST00000377507.8
TNF receptor superfamily member 9
chr1_-_120054225 2.10 ENST00000602566.6
notch receptor 2
chr15_+_67125707 2.00 ENST00000540846.6
SMAD family member 3
chr7_-_93148345 1.69 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr4_+_95051671 1.68 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr2_-_216013582 1.67 ENST00000620139.4
melanoregulin
chr4_+_94974984 1.64 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr9_+_97412062 1.56 ENST00000355295.5
tudor domain containing 7
chr15_-_55249029 1.37 ENST00000566877.5
RAB27A, member RAS oncogene family
chr18_+_58196736 1.33 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr11_-_5154757 1.32 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr5_+_98773651 1.31 ENST00000513185.3
repulsive guidance molecule BMP co-receptor b
chr7_-_16833411 1.18 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr9_-_83063159 1.05 ENST00000340717.4
RAS and EF-hand domain containing
chr19_+_21082140 1.00 ENST00000616183.1
ENST00000596053.5
zinc finger protein 714
chr12_-_21774688 0.97 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr22_-_37844308 0.94 ENST00000411961.6
ENST00000434930.1
ENST00000215941.9
ankyrin repeat domain 54
chr12_-_21775045 0.91 ENST00000667884.1
potassium inwardly rectifying channel subfamily J member 8
chr1_-_7853054 0.89 ENST00000361696.10
urotensin 2
chr12_+_45292674 0.86 ENST00000679426.1
ENST00000441606.2
anoctamin 6
chr10_+_24466487 0.77 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr18_-_5396265 0.77 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr17_-_29761390 0.75 ENST00000324677.12
slingshot protein phosphatase 2
chr22_-_32255344 0.72 ENST00000266086.6
solute carrier family 5 member 4
chr11_+_55635113 0.70 ENST00000641760.1
olfactory receptor family 4 subfamily P member 4
chr3_+_63967738 0.69 ENST00000484332.1
ataxin 7
chr9_-_130939205 0.68 ENST00000372338.9
fibrinogen C domain containing 1
chr17_-_29761415 0.65 ENST00000649863.1
slingshot protein phosphatase 2
chr2_-_51032151 0.65 ENST00000628515.2
neurexin 1
chr4_+_71062642 0.64 ENST00000649996.1
solute carrier family 4 member 4
chr1_-_237004440 0.63 ENST00000464121.3
metallothionein 1H like 1
chr5_-_58999885 0.62 ENST00000317118.12
phosphodiesterase 4D
chr6_+_29301701 0.62 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr16_+_25216943 0.61 ENST00000219660.6
aquaporin 8
chr10_-_127892930 0.61 ENST00000368671.4
clarin 3
chr7_-_143408848 0.59 ENST00000275815.4
EPH receptor A1
chr12_+_54284258 0.58 ENST00000677666.1
heterogeneous nuclear ribonucleoprotein A1
chr5_+_177304571 0.58 ENST00000503853.1
PRELI domain containing 1
chr4_-_68670648 0.56 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr5_-_149063021 0.53 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr7_-_41703062 0.50 ENST00000242208.5
inhibin subunit beta A
chr8_+_12104389 0.48 ENST00000400085.7
zinc finger protein 705D
chr1_+_74235377 0.46 ENST00000326637.8
TNNI3 interacting kinase
chr2_-_189179754 0.46 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr10_+_102226293 0.45 ENST00000370005.4
ELOVL fatty acid elongase 3
chr11_+_111245725 0.44 ENST00000280325.7
chromosome 11 open reading frame 53
chr4_-_39977836 0.44 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr4_+_87832917 0.44 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr12_-_52434363 0.43 ENST00000252245.6
keratin 75
chr4_-_168318770 0.43 ENST00000680771.1
ENST00000514995.2
DExD/H-box helicase 60
chrX_+_141894666 0.42 ENST00000544766.5
MAGE family member C3
chr4_-_168318743 0.41 ENST00000393743.8
DExD/H-box helicase 60
chr19_+_21082224 0.41 ENST00000620627.1
zinc finger protein 714
chr5_-_43515128 0.40 ENST00000306862.7
chromosome 5 open reading frame 34
chr10_-_113854368 0.40 ENST00000369305.1
DNA cross-link repair 1A
chrX_+_106693838 0.39 ENST00000324342.7
ring finger protein 128
chr8_-_20183090 0.39 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr3_-_53891836 0.39 ENST00000495461.6
ENST00000541726.5
selenoprotein K
chr17_-_8119047 0.37 ENST00000318227.4
arachidonate lipoxygenase 3
chr16_-_20327801 0.37 ENST00000381360.9
glycoprotein 2
chrX_+_66164340 0.37 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr10_+_84173793 0.37 ENST00000372126.4
chromosome 10 open reading frame 99
chr8_-_20183127 0.36 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr1_-_86383078 0.36 ENST00000460698.6
outer dense fiber of sperm tails 2 like
chr14_+_51989609 0.36 ENST00000556760.5
RNA transcription, translation and transport factor
chr19_+_48393657 0.36 ENST00000263269.4
glutamate ionotropic receptor NMDA type subunit 2D
chr5_+_72848161 0.35 ENST00000506351.6
transportin 1
chr7_+_142111739 0.34 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr7_+_57450171 0.33 ENST00000420713.2
zinc finger protein 716
chr9_+_128787331 0.33 ENST00000223865.8
TBC1 domain family member 13
chr9_-_92293674 0.33 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
isoleucyl-tRNA synthetase 1
chr14_-_56805648 0.33 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr5_-_148654130 0.33 ENST00000360693.7
5-hydroxytryptamine receptor 4
chr1_+_24319342 0.32 ENST00000361548.9
grainyhead like transcription factor 3
chr2_-_210303608 0.32 ENST00000341685.8
myosin light chain 1
chr7_-_25228485 0.32 ENST00000222674.2
neuropeptide VF precursor
chrX_+_66164210 0.32 ENST00000343002.7
ENST00000336279.9
hephaestin
chr4_+_70383123 0.32 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr6_+_133953210 0.31 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr5_-_16738341 0.31 ENST00000515803.5
myosin X
chr19_+_47994625 0.31 ENST00000339841.7
epididymal sperm binding protein 1
chr6_-_26189101 0.30 ENST00000614247.2
H4 clustered histone 4
chr1_+_13585453 0.30 ENST00000487038.5
ENST00000475043.5
podoplanin
chrX_+_65488735 0.30 ENST00000338957.4
zinc finger CCCH-type containing 12B
chr19_+_47994696 0.29 ENST00000596043.5
ENST00000597519.5
epididymal sperm binding protein 1
chr17_-_74776323 0.29 ENST00000582870.5
ENST00000581136.5
ENST00000579218.5
ENST00000583476.5
ENST00000580301.5
ENST00000583757.5
ENST00000357814.8
ENST00000582524.5
N-acetyltransferase 9 (putative)
chr14_+_20110739 0.28 ENST00000641386.2
ENST00000641633.2
olfactory receptor family 4 subfamily K member 17
chr14_+_51989508 0.28 ENST00000261700.8
RNA transcription, translation and transport factor
chr1_-_28058087 0.28 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr11_+_60280531 0.28 ENST00000532114.6
membrane spanning 4-domains A4A
chr8_+_17027230 0.27 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr16_-_20327426 0.27 ENST00000575582.5
ENST00000341642.9
ENST00000381362.8
ENST00000572347.5
ENST00000572478.5
ENST00000302555.10
glycoprotein 2
chr6_-_22302797 0.27 ENST00000651757.1
prolactin
chr11_+_72189528 0.27 ENST00000312293.9
folate receptor alpha
chr12_-_62935117 0.27 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr4_-_71784046 0.26 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr11_-_60906564 0.26 ENST00000541371.5
ENST00000227524.9
pre-mRNA processing factor 19
chr4_-_122456725 0.25 ENST00000226730.5
interleukin 2
chr13_+_23570370 0.25 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr1_-_23559490 0.25 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr6_+_111087495 0.25 ENST00000612036.4
ENST00000368851.10
solute carrier family 16 member 10
chr19_-_10309783 0.25 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr2_-_223602284 0.25 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr17_+_27609836 0.25 ENST00000582410.5
kinase suppressor of ras 1
chr6_+_158312459 0.25 ENST00000367097.8
TUB like protein 4
chr11_+_72189659 0.25 ENST00000393681.6
folate receptor alpha
chr2_+_157257687 0.24 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr4_+_154563003 0.24 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr20_-_7940444 0.24 ENST00000378789.4
hydroxyacid oxidase 1
chr5_+_72848115 0.23 ENST00000679378.1
transportin 1
chr19_+_926001 0.23 ENST00000263620.8
AT-rich interaction domain 3A
chr7_+_134779625 0.23 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr5_+_122129533 0.23 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr15_-_20541800 0.22 ENST00000619213.1
golgin A6 family like 6
chr14_-_25010604 0.22 ENST00000550887.5
syntaxin binding protein 6
chr1_+_154429315 0.21 ENST00000476006.5
interleukin 6 receptor
chr9_-_83956677 0.21 ENST00000376344.8
chromosome 9 open reading frame 64
chr3_-_108953870 0.21 ENST00000261047.8
guanylate cyclase activator 1C
chr6_+_25754699 0.21 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr11_+_60280577 0.21 ENST00000679988.1
membrane spanning 4-domains A4A
chr4_+_185395979 0.20 ENST00000507753.1
ankyrin repeat domain 37
chr3_+_172039556 0.20 ENST00000415807.7
ENST00000421757.5
fibronectin type III domain containing 3B
chr21_-_30829755 0.20 ENST00000621162.1
keratin associated protein 7-1
chr17_-_41489907 0.20 ENST00000328119.11
keratin 36
chr7_+_134779663 0.20 ENST00000361901.6
caldesmon 1
chr9_-_92878018 0.19 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr16_-_21652598 0.19 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr3_-_9880250 0.19 ENST00000423850.5
ENST00000336832.7
ENST00000675828.1
ENST00000618572.4
ENST00000455015.6
cell death inducing DFFA like effector c
chr19_+_21082190 0.18 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
zinc finger protein 714
chr8_+_75539893 0.17 ENST00000674002.1
hepatocyte nuclear factor 4 gamma
chr9_-_28670285 0.17 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr3_-_46027477 0.17 ENST00000309285.4
ENST00000395946.2
X-C motif chemokine receptor 1
chr11_+_119067774 0.17 ENST00000621676.5
ENST00000614944.4
VPS11 core subunit of CORVET and HOPS complexes
chr20_+_59300589 0.17 ENST00000337938.7
ENST00000371025.7
endothelin 3
chr1_+_192158448 0.16 ENST00000367460.4
regulator of G protein signaling 18
chr22_+_50170720 0.16 ENST00000159647.9
ENST00000395842.3
pannexin 2
chr8_+_75539862 0.16 ENST00000396423.4
hepatocyte nuclear factor 4 gamma
chr6_+_47698538 0.16 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr8_+_106726115 0.15 ENST00000521592.5
oxidation resistance 1
chr19_-_43935234 0.15 ENST00000269973.10
zinc finger protein 45
chr10_+_73744346 0.15 ENST00000345254.9
ENST00000339365.2
SEC24 homolog C, COPII coat complex component
chr5_-_148654522 0.15 ENST00000377888.8
5-hydroxytryptamine receptor 4
chr5_+_136132772 0.15 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD family member 5
chr2_+_186506713 0.14 ENST00000445547.1
zinc finger CCCH-type containing 15
chr15_+_22458903 0.14 ENST00000620691.4
golgin A6 family like 22
chrX_-_13319952 0.14 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chrX_-_15600953 0.14 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr11_-_3379212 0.14 ENST00000429541.6
ENST00000532539.1
ENST00000343338.11
ENST00000620374.4
zinc finger protein 195
chr6_-_143450662 0.14 ENST00000237283.9
adenosine deaminase tRNA specific 2
chr6_+_47698574 0.14 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr12_-_18090185 0.13 ENST00000229002.6
ENST00000538724.6
RERG like
chr15_+_40594001 0.13 ENST00000346991.9
ENST00000528975.5
kinetochore scaffold 1
chr6_+_26156323 0.13 ENST00000304218.6
H1.4 linker histone, cluster member
chr3_+_98130721 0.13 ENST00000641874.1
olfactory receptor family 5 subfamily H member 1
chr3_-_197184131 0.13 ENST00000452595.5
discs large MAGUK scaffold protein 1
chr12_-_118359105 0.13 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr20_+_59300703 0.13 ENST00000395654.3
endothelin 3
chr1_+_34176900 0.13 ENST00000488417.2
chromosome 1 open reading frame 94
chr11_-_3379110 0.12 ENST00000005082.13
ENST00000534569.5
ENST00000438262.6
ENST00000528796.5
ENST00000528410.5
ENST00000529678.5
ENST00000618467.4
ENST00000354599.10
ENST00000399602.9
ENST00000526601.5
ENST00000525502.5
ENST00000533036.5
zinc finger protein 195
chr18_+_63542365 0.12 ENST00000269491.6
ENST00000382768.2
serpin family B member 12
chr3_-_108953762 0.12 ENST00000393963.7
ENST00000471108.1
guanylate cyclase activator 1C
chr8_+_106726012 0.12 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr3_+_41200104 0.12 ENST00000643297.1
ENST00000450969.6
catenin beta 1
chr6_+_27815010 0.12 ENST00000621112.2
H2B clustered histone 14
chr15_-_41544243 0.11 ENST00000567866.5
ENST00000304330.9
ENST00000561603.5
ENST00000566863.1
RNA polymerase II associated protein 1
chr1_+_248038172 0.11 ENST00000366479.4
olfactory receptor family 2 subfamily L member 2
chr20_+_59300547 0.11 ENST00000644821.1
endothelin 3
chr6_+_12957301 0.11 ENST00000676234.1
phosphatase and actin regulator 1
chr13_-_45201027 0.11 ENST00000379108.2
potassium channel tetramerization domain containing 4
chr11_-_58844484 0.10 ENST00000532258.1
glycine-N-acyltransferase like 2
chr6_+_46793379 0.10 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr11_-_13496018 0.10 ENST00000529816.1
parathyroid hormone
chr20_-_462485 0.10 ENST00000681414.1
ENST00000680050.1
ENST00000681129.1
ENST00000354200.5
ENST00000679895.1
ENST00000681551.1
ENST00000681539.1
TBC1 domain family member 20
chr20_+_2295994 0.10 ENST00000381458.6
transglutaminase 3
chr5_-_36001006 0.10 ENST00000625798.2
UDP glycosyltransferase family 3 member A1
chr8_-_13514821 0.10 ENST00000276297.9
DLC1 Rho GTPase activating protein
chr5_-_39270623 0.09 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr4_+_70397931 0.09 ENST00000399575.7
opiorphin prepropeptide
chr14_+_56117702 0.09 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr11_+_60378494 0.09 ENST00000534016.5
membrane spanning 4-domains A7
chr11_-_58844695 0.08 ENST00000287275.6
glycine-N-acyltransferase like 2
chr12_-_55296569 0.08 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr2_-_51032091 0.08 ENST00000637511.1
ENST00000405472.7
ENST00000405581.3
ENST00000401669.7
neurexin 1
chr17_-_48728705 0.08 ENST00000290295.8
homeobox B13
chr7_+_129144691 0.08 ENST00000486685.3
tetraspanin 33
chr20_+_59300402 0.08 ENST00000311585.11
ENST00000371028.6
endothelin 3
chr11_+_60378475 0.07 ENST00000358246.5
membrane spanning 4-domains A7
chr5_+_140882116 0.07 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr11_-_4697831 0.07 ENST00000641159.1
ENST00000396950.4
ENST00000532598.1
olfactory receptor family 51 subfamily C member 1 pseudogene
olfactory receptor family 51 subfamily E member 2
chr4_-_163613505 0.07 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr2_-_169031317 0.07 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr14_-_60486021 0.07 ENST00000555476.5
ENST00000321731.8
chromosome 14 open reading frame 39
chr20_+_31514410 0.07 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr16_-_1884231 0.07 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr14_+_55027576 0.07 ENST00000339298.2
suppressor of cytokine signaling 4
chr11_-_13495984 0.06 ENST00000282091.6
parathyroid hormone
chr7_+_65373839 0.06 ENST00000431504.1
ENST00000328747.12
zinc finger protein 92
chr7_+_65373873 0.05 ENST00000450302.2
zinc finger protein 92

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.4 2.5 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.4 4.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 2.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 0.9 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 1.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.2 1.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.9 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.2 0.5 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 1.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 2.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.6 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.1 0.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.7 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 1.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 1.7 GO:0032402 establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 4.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0002679 respiratory burst involved in defense response(GO:0002679) positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 1.4 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0006833 water transport(GO:0006833)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 3.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.9 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.5 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 3.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 2.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.6 GO:0033391 chromatoid body(GO:0033391)
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.7 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 4.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 2.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 1.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.3 3.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 2.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 0.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 4.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.5 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 2.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.9 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 1.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 2.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.5 PID BMP PATHWAY BMP receptor signaling
0.0 2.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 4.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 2.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 4.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 3.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling