Inflammatory response time course, HUVEC (Wada, 2009)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CEBPB Links Ensembl NCBI GeneCards UniProt	ENSG00000172216.6	CEBPB

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPB	hg38_v1_chr20_+_50190821_50190839	0.55	4.0e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr15_+_88638947 Show fit	14.85	ENST00000559876.2	ISG20 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr15_+_88639009 Show fit	12.58	ENST00000306072.10	ISG20 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr1_+_212608628 Show fit	11.05	ENST00000613954.4 ENST00000341491.9 ENST00000366985.5	ATF3 Links Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 3
chr4_-_138242325 Show fit	10.42	ENST00000280612.9	SLC7A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 11
chr11_-_102798148 Show fit	9.57	ENST00000315274.7	MMP1 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 1
chr5_-_151093566 Show fit	9.53	ENST00000521001.1	TNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr15_-_79971164 Show fit	8.95	ENST00000335661.6 ENST00000267953.4 ENST00000677151.1	BCL2A1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 related protein A1
chr5_-_142325001 Show fit	7.84	ENST00000344120.4 ENST00000434127.3	SPRY4 Links Ensembl NCBI GeneCards UniProt Show fit	sprouty RTK signaling antagonist 4
chr6_+_32844789 Show fit	6.80	ENST00000414474.5	PSMB9 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr6_+_127577168 Show fit	6.42	ENST00000329722.8	C6orf58 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 6 open reading frame 58
chr12_-_55842950 Show fit	4.85	ENST00000548629.5	MMP19 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 19
chr7_-_116030735 Show fit	4.70	ENST00000393485.5	TFEC Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr6_+_125781108 Show fit	4.67	ENST00000368357.7	NCOA7 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 7
chr5_+_126423122 Show fit	4.60	ENST00000515200.5	GRAMD2B Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr5_+_126423176 Show fit	4.58	ENST00000542322.5 ENST00000544396.5	GRAMD2B Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr5_+_126423363 Show fit	4.54	ENST00000285689.8	GRAMD2B Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr1_-_149936324 Show fit	4.08	ENST00000369140.7	MTMR11 Links Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 11
chr3_-_71130557 Show fit	3.95	ENST00000497355.7	FOXP1 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr11_-_3057386 Show fit	3.81	ENST00000529772.5 ENST00000278224.13 ENST00000380525.9	CARS1 Links Ensembl NCBI GeneCards UniProt Show fit	cysteinyl-tRNA synthetase 1
chr15_+_40953463 Show fit	3.58	ENST00000617768.5	CHAC1 Links Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr20_+_381246 Show fit	3.45	ENST00000449710.5 ENST00000422053.3	TRIB3 Links Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 3
chr7_-_116030750 Show fit	3.43	ENST00000265440.12 ENST00000320239.11	TFEC Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chrX_+_9463272 Show fit	3.37	ENST00000407597.7 ENST00000380961.5 ENST00000424279.6	TBL1X Links Ensembl NCBI GeneCards UniProt Show fit	transducin beta like 1 X-linked
chr1_+_218345326 Show fit	3.29	ENST00000366930.9	TGFB2 Links Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta 2
chr20_+_380747 Show fit	3.24	ENST00000217233.9	TRIB3 Links Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 3
chr2_+_64989343 Show fit	3.20	ENST00000234256.4	SLC1A4 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 4
chr1_-_149936816 Show fit	3.15	ENST00000439741.4	MTMR11 Links Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 11
chr15_+_62066975 Show fit	3.14	ENST00000355522.5	C2CD4A Links Ensembl NCBI GeneCards UniProt Show fit	C2 calcium dependent domain containing 4A
chr2_-_174846405 Show fit	3.08	ENST00000409597.5 ENST00000413882.6	CHN1 Links Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr7_+_28685968 Show fit	2.91	ENST00000396298.6	CREB5 Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 5
chr12_-_6342020 Show fit	2.83	ENST00000540022.5 ENST00000536194.1	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr6_-_32844643 Show fit	2.77	ENST00000374881.3	PSMB8 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 8
chr3_-_187745460 Show fit	2.67	ENST00000406870.7	BCL6 Links Ensembl NCBI GeneCards UniProt Show fit	BCL6 transcription repressor
chr16_+_56936654 Show fit	2.66	ENST00000563911.5	HERPUD1 Links Ensembl NCBI GeneCards UniProt Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr1_+_28259473 Show fit	2.59	ENST00000253063.4	SESN2 Links Ensembl NCBI GeneCards UniProt Show fit	sestrin 2
chr6_-_17987463 Show fit	2.58	ENST00000378814.9 ENST00000636847.1 ENST00000378843.6 ENST00000378826.6 ENST00000502704.2 ENST00000259711.11	KIF13A Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 13A
chr9_-_114806031 Show fit	2.44	ENST00000374045.5	TNFSF15 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 15
chr15_+_70853239 Show fit	2.44	ENST00000544974.6 ENST00000558546.5	LRRC49 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 49
chr3_+_141386862 Show fit	2.37	ENST00000513258.5	ZBTB38 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr5_+_52787899 Show fit	2.34	ENST00000274311.3 ENST00000282588.7	PELO Links Ensembl NCBI GeneCards UniProt Show fit ITGA1 Links Ensembl NCBI GeneCards UniProt Show fit	pelota mRNA surveillance and ribosome rescue factor integrin subunit alpha 1
chr1_-_196608359 Show fit	2.12	ENST00000609185.5 ENST00000451324.6 ENST00000367433.9 ENST00000294725.14	KCNT2 Links Ensembl NCBI GeneCards UniProt Show fit	potassium sodium-activated channel subfamily T member 2
chr6_+_31927683 Show fit	2.12	ENST00000456570.5	ENSG00000244255.5 Links Ensembl NCBI GeneCards UniProt Show fit	novel complement component 2 (C2) and complement factor B (CFB) protein
chr16_+_56932134 Show fit	2.03	ENST00000439977.7 ENST00000300302.9 ENST00000344114.8 ENST00000379792.6	HERPUD1 Links Ensembl NCBI GeneCards UniProt Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr22_+_35381086 Show fit	1.99	ENST00000216117.9 ENST00000677931.1 ENST00000679074.1	HMOX1 Links Ensembl NCBI GeneCards UniProt Show fit	heme oxygenase 1
chr3_+_101849505 Show fit	1.99	ENST00000326151.9 ENST00000326172.9	NFKBIZ Links Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor zeta
chr3_-_66500973 Show fit	1.93	ENST00000383703.3 ENST00000273261.8	LRIG1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and immunoglobulin like domains 1
chr10_+_110005804 Show fit	1.89	ENST00000360162.7	ADD3 Links Ensembl NCBI GeneCards UniProt Show fit	adducin 3
chr12_-_6342066 Show fit	1.88	ENST00000162749.7 ENST00000440083.6	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr5_-_138543198 Show fit	1.84	ENST00000507939.5 ENST00000572514.5 ENST00000499810.6 ENST00000360541.10	ETF1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation termination factor 1
chr1_-_203229660 Show fit	1.81	ENST00000255427.7 ENST00000367229.6	CHIT1 Links Ensembl NCBI GeneCards UniProt Show fit	chitinase 1
chr19_-_46784733 Show fit	1.73	ENST00000593713.1 ENST00000598022.1 ENST00000434726.6	SLC1A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 5
chr22_-_30246739 Show fit	1.60	ENST00000403987.3 ENST00000249075.4	LIF Links Ensembl NCBI GeneCards UniProt Show fit	LIF interleukin 6 family cytokine
chrX_-_119150579 Show fit	1.60	ENST00000402510.2	KIAA1210 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1210
chr1_-_204411804 Show fit	1.60	ENST00000367188.5	PPP1R15B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 15B
chr19_-_46784905 Show fit	1.57	ENST00000594991.5	SLC1A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 5
chr8_-_38150943 Show fit	1.54	ENST00000276449.9	STAR Links Ensembl NCBI GeneCards UniProt Show fit	steroidogenic acute regulatory protein
chr11_+_62881686 Show fit	1.53	ENST00000536981.6 ENST00000539891.6	SLC3A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 2
chr1_-_32817311 Show fit	1.51	ENST00000373477.9 ENST00000675785.1	YARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-tRNA synthetase 1
chr1_-_36482904 Show fit	1.47	ENST00000373106.6	CSF3R Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 3 receptor
chr5_-_179620933 Show fit	1.43	ENST00000521173.5	HNRNPH1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein H1
chr5_-_59356962 Show fit	1.39	ENST00000405755.6	PDE4D Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr1_-_149861210 Show fit	1.37	ENST00000579512.2	H4C15 Links Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 15
chr16_+_1309714 Show fit	1.37	ENST00000566587.5	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 I
chr12_-_55842927 Show fit	1.32	ENST00000322569.9 ENST00000409200.7	MMP19 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 19
chr19_+_35745613 Show fit	1.30	ENST00000222266.2 ENST00000587708.7	PSENEN Links Ensembl NCBI GeneCards UniProt Show fit	presenilin enhancer, gamma-secretase subunit
chr19_+_48755512 Show fit	1.29	ENST00000593756.6	FGF21 Links Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 21
chr1_-_220046432 Show fit	1.27	ENST00000609181.5 ENST00000366923.8	EPRS1 Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-prolyl-tRNA synthetase 1
chr19_+_35745590 Show fit	1.27	ENST00000591949.1	PSENEN Links Ensembl NCBI GeneCards UniProt Show fit	presenilin enhancer, gamma-secretase subunit
chr3_+_141386393 Show fit	1.21	ENST00000503809.5	ZBTB38 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr19_+_33374312 Show fit	1.20	ENST00000585933.2	CEBPG Links Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein gamma
chr17_-_81937221 Show fit	1.18	ENST00000402252.6 ENST00000583564.5 ENST00000585244.1 ENST00000337943.9 ENST00000579698.5	PYCR1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 1
chr15_-_48963912 Show fit	1.18	ENST00000332408.9	SHC4 Links Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 4
chr10_+_113125536 Show fit	1.17	ENST00000349937.7	TCF7L2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr17_-_81937277 Show fit	1.16	ENST00000405481.8 ENST00000329875.13 ENST00000585215.5	PYCR1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 1
chr1_+_149832647 Show fit	1.12	ENST00000578186.2	H4C14 Links Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 14
chr2_-_216694794 Show fit	1.10	ENST00000449583.1	IGFBP5 Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 5
chr6_+_30720335 Show fit	1.10	ENST00000327892.13	TUBB Links Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr3_+_128051610 Show fit	1.08	ENST00000464451.5	SEC61A1 Links Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit alpha 1
chr17_-_81937320 Show fit	1.08	ENST00000577624.5 ENST00000403172.8 ENST00000619204.4 ENST00000629768.2	PYCR1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 1
chr1_+_239719542 Show fit	1.06	ENST00000448020.1	CHRM3 Links Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor muscarinic 3
chr20_+_57561103 Show fit	1.06	ENST00000319441.6	PCK1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoenolpyruvate carboxykinase 1
chr6_-_158819355 Show fit	1.05	ENST00000367075.4	EZR Links Ensembl NCBI GeneCards UniProt Show fit	ezrin
chr2_-_219309484 Show fit	1.02	ENST00000409251.7 ENST00000451506.5 ENST00000446182.5	PTPRN Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type N
chr9_-_92293674 Show fit	1.00	ENST00000683679.1 ENST00000683565.1 ENST00000684557.1 ENST00000682578.1 ENST00000443024.7 ENST00000375643.7 ENST00000683469.1	IARS1 Links Ensembl NCBI GeneCards UniProt Show fit	isoleucyl-tRNA synthetase 1
chr19_-_4540028 Show fit	0.98	ENST00000306390.7	LRG1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich alpha-2-glycoprotein 1
chr17_+_41689862 Show fit	0.98	ENST00000586699.1	EIF1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1
chr5_+_38846002 Show fit	0.97	ENST00000274276.8	OSMR Links Ensembl NCBI GeneCards UniProt Show fit	oncostatin M receptor
chr17_-_43833137 Show fit	0.96	ENST00000398389.9	MPP3 Links Ensembl NCBI GeneCards UniProt Show fit	membrane palmitoylated protein 3
chr5_+_33440947 Show fit	0.92	ENST00000455217.6 ENST00000265112.8	TARS1 Links Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr20_+_41340878 Show fit	0.92	ENST00000632009.1	LPIN3 Links Ensembl NCBI GeneCards UniProt Show fit	lipin 3
chr20_+_41340780 Show fit	0.91	ENST00000373257.8	LPIN3 Links Ensembl NCBI GeneCards UniProt Show fit	lipin 3
chr17_+_67377413 Show fit	0.87	ENST00000580974.5	PITPNC1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol transfer protein cytoplasmic 1
chr5_+_38845824 Show fit	0.87	ENST00000502536.5	OSMR Links Ensembl NCBI GeneCards UniProt Show fit	oncostatin M receptor
chr2_-_219309350 Show fit	0.86	ENST00000295718.7	PTPRN Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type N
chrX_-_54998530 Show fit	0.86	ENST00000545676.5	PFKFB1 Links Ensembl NCBI GeneCards UniProt Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_+_48756067 Show fit	0.85	ENST00000222157.5	FGF21 Links Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 21
chr1_-_23531206 Show fit	0.83	ENST00000361729.3	E2F2 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 2
chr1_+_50108856 Show fit	0.81	ENST00000650764.1 ENST00000494555.2 ENST00000371824.7 ENST00000371823.8 ENST00000652693.1	ELAVL4 Links Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr9_-_34691204 Show fit	0.79	ENST00000378800.3 ENST00000311925.7	CCL19 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 19
chr5_+_170353480 Show fit	0.79	ENST00000377360.8	KCNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel interacting protein 1
chr3_-_48016400 Show fit	0.78	ENST00000434267.5 ENST00000683076.1 ENST00000633710.1	MAP4 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 4
chr12_-_52680398 Show fit	0.76	ENST00000252244.3	KRT1 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 1
chr5_+_33440696 Show fit	0.75	ENST00000502553.5 ENST00000514259.5	TARS1 Links Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr17_+_58148384 Show fit	0.75	ENST00000268912.6 ENST00000641449.1	OR4D1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 4 subfamily D member 1
chr5_-_132777866 Show fit	0.75	ENST00000448933.5	SEPTIN8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr12_+_57229694 Show fit	0.74	ENST00000557487.5 ENST00000328923.8 ENST00000555634.5 ENST00000556689.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chrX_-_152451273 Show fit	0.74	ENST00000370314.9	GABRA3 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha3
chr17_-_66220630 Show fit	0.71	ENST00000585162.1	APOH Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H
chr3_+_157436842 Show fit	0.70	ENST00000295927.4	PTX3 Links Ensembl NCBI GeneCards UniProt Show fit	pentraxin 3
chr1_-_150629110 Show fit	0.70	ENST00000513281.5 ENST00000361631.9 ENST00000361532.9	ENSA Links Ensembl NCBI GeneCards UniProt Show fit	endosulfine alpha
chr12_-_95996302 Show fit	0.68	ENST00000261208.8 ENST00000538703.5 ENST00000541929.5	HAL Links Ensembl NCBI GeneCards UniProt Show fit	histidine ammonia-lyase
chr6_+_150865815 Show fit	0.68	ENST00000367308.8	MTHFD1L Links Ensembl NCBI GeneCards UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr1_-_27626229 Show fit	0.63	ENST00000399173.5	FGR Links Ensembl NCBI GeneCards UniProt Show fit	FGR proto-oncogene, Src family tyrosine kinase
chr3_-_3109980 Show fit	0.62	ENST00000256452.7 ENST00000311981.12 ENST00000430514.6 ENST00000456302.5	IL5RA Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 5 receptor subunit alpha
chr11_-_31811231 Show fit	0.61	ENST00000438681.6	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr12_-_57520480 Show fit	0.61	ENST00000642841.1 ENST00000547303.5 ENST00000552740.5 ENST00000547526.1 ENST00000346473.8 ENST00000551116.5	ENSG00000285133.1 Links Ensembl NCBI GeneCards UniProt Show fit DDIT3 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein DNA damage inducible transcript 3
chr10_+_49299159 Show fit	0.60	ENST00000374144.8	C10orf71 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 71
chr12_-_46268989 Show fit	0.59	ENST00000549049.5 ENST00000439706.5 ENST00000398637.10	SLC38A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 1
chrX_-_107000185 Show fit	0.59	ENST00000355610.9	MORC4 Links Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 4
chrX_+_13569593 Show fit	0.59	ENST00000361306.6 ENST00000380602.3	EGFL6 Links Ensembl NCBI GeneCards UniProt Show fit	EGF like domain multiple 6
chr11_-_31811034 Show fit	0.59	ENST00000638250.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr10_+_26438317 Show fit	0.58	ENST00000376236.9	APBB1IP Links Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 1 interacting protein
chr3_+_100114911 Show fit	0.56	ENST00000489081.5	CMSS1 Links Ensembl NCBI GeneCards UniProt Show fit	cms1 ribosomal small subunit homolog
chr17_+_30921935 Show fit	0.55	ENST00000581285.5 ENST00000330889.8	ADAP2 Links Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with dual PH domains 2
chr2_+_46542474 Show fit	0.55	ENST00000238738.9	RHOQ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member Q
chr1_+_25430854 Show fit	0.54	ENST00000399766.7	MACO1 Links Ensembl NCBI GeneCards UniProt Show fit	macoilin 1
chr16_-_4273014 Show fit	0.52	ENST00000204517.11	TFAP4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-4
chr19_-_35745391 Show fit	0.52	ENST00000378975.8 ENST00000587886.2 ENST00000412391.6 ENST00000292879.9	U2AF1L4 Links Ensembl NCBI GeneCards UniProt Show fit	U2 small nuclear RNA auxiliary factor 1 like 4
chr17_+_58166982 Show fit	0.52	ENST00000545221.2	OR4D2 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 4 subfamily D member 2
chr6_+_31971831 Show fit	0.51	ENST00000375331.7 ENST00000375333.3	STK19 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 19
chr19_-_43619591 Show fit	0.51	ENST00000598676.1 ENST00000300811.8	ZNF428 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 428
chr20_-_34112205 Show fit	0.50	ENST00000374980.3	EIF2S2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 subunit beta
chr2_-_178702479 Show fit	0.50	ENST00000414766.5	TTN Links Ensembl NCBI GeneCards UniProt Show fit	titin
chr11_+_114296347 Show fit	0.50	ENST00000299964.4	NNMT Links Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr17_+_30921899 Show fit	0.50	ENST00000581548.5 ENST00000580525.5	ADAP2 Links Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with dual PH domains 2
chr4_-_156970903 Show fit	0.50	ENST00000422544.2	PDGFC Links Ensembl NCBI GeneCards UniProt Show fit	platelet derived growth factor C
chr6_+_150866333 Show fit	0.48	ENST00000618312.4 ENST00000423867.2	MTHFD1L Links Ensembl NCBI GeneCards UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr1_+_25430885 Show fit	0.48	ENST00000374343.5	MACO1 Links Ensembl NCBI GeneCards UniProt Show fit	macoilin 1
chr15_-_100528896 Show fit	0.47	ENST00000679737.1	CERS3 Links Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 3
chr11_-_31811112 Show fit	0.47	ENST00000640242.1 ENST00000640613.1 ENST00000606377.7	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr11_-_31811140 Show fit	0.46	ENST00000639916.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr11_-_31810991 Show fit	0.45	ENST00000640684.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr19_-_32869741 Show fit	0.45	ENST00000590341.5 ENST00000587772.1 ENST00000023064.9	SLC7A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 9
chr7_+_99408609 Show fit	0.45	ENST00000403633.6	BUD31 Links Ensembl NCBI GeneCards UniProt Show fit	BUD31 homolog
chr14_+_75428011 Show fit	0.44	ENST00000651602.1 ENST00000559060.5	JDP2 Links Ensembl NCBI GeneCards UniProt Show fit	Jun dimerization protein 2
chr10_+_55599041 Show fit	0.43	ENST00000512524.4	MTRNR2L5 Links Ensembl NCBI GeneCards UniProt Show fit	MT-RNR2 like 5
chr7_-_77199808 Show fit	0.43	ENST00000248598.6	FGL2 Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen like 2
chr5_-_102296260 Show fit	0.43	ENST00000310954.7	SLCO4C1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 4C1
chr17_-_40822604 Show fit	0.42	ENST00000269576.6 ENST00000635956.2	KRT10 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 10
chr19_+_48993864 Show fit	0.41	ENST00000595090.6	RUVBL2 Links Ensembl NCBI GeneCards UniProt Show fit	RuvB like AAA ATPase 2
chr3_-_100114488 Show fit	0.41	ENST00000477258.2 ENST00000354552.7 ENST00000331335.9 ENST00000398326.2	FILIP1L Links Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1 like
chr22_-_40862070 Show fit	0.41	ENST00000307221.5	DNAJB7 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B7
chr17_+_58238426 Show fit	0.40	ENST00000421678.6 ENST00000262290.9 ENST00000543544.5	LPO Links Ensembl NCBI GeneCards UniProt Show fit	lactoperoxidase
chr12_+_9971402 Show fit	0.39	ENST00000304361.9 ENST00000396507.7 ENST00000434319.6	CLEC12A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 12 member A
chr13_-_103066411 Show fit	0.39	ENST00000245312.5	SLC10A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 2
chr17_-_48626325 Show fit	0.37	ENST00000311177.7	HOXB9 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox B9
chr11_-_31810657 Show fit	0.31	ENST00000379109.7	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr3_-_3110347 Show fit	0.30	ENST00000383846.5 ENST00000427088.1 ENST00000446632.7 ENST00000418488.6 ENST00000438560.5	IL5RA Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 5 receptor subunit alpha
chr4_-_38856807 Show fit	0.30	ENST00000506146.5 ENST00000436693.6 ENST00000508254.5 ENST00000514655.1	TLR1 Links Ensembl NCBI GeneCards UniProt Show fit TLR6 Links Ensembl NCBI GeneCards UniProt Show fit	toll like receptor 1 toll like receptor 6
chr6_+_31927486 Show fit	0.30	ENST00000442278.6	C2 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2
chr19_+_43951216 Show fit	0.30	ENST00000591168.5 ENST00000587682.6 ENST00000251269.9	ZNF221 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 221
chr3_+_141387616 Show fit	0.29	ENST00000509883.5	ZBTB38 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr6_+_31927703 Show fit	0.29	ENST00000418949.6 ENST00000299367.10 ENST00000383177.7 ENST00000477310.1	C2 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000244255.5 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2 novel complement component 2 (C2) and complement factor B (CFB) protein
chr5_-_146182475 Show fit	0.27	ENST00000674158.1 ENST00000674191.1 ENST00000274562.13	LARS1 Links Ensembl NCBI GeneCards UniProt Show fit	leucyl-tRNA synthetase 1
chr21_-_43075831 Show fit	0.26	ENST00000398158.5 ENST00000398165.8	CBS Links Ensembl NCBI GeneCards UniProt Show fit	cystathionine beta-synthase
chr1_-_150629470 Show fit	0.26	ENST00000638926.1 ENST00000503241.1 ENST00000369016.8 ENST00000339643.9 ENST00000271690.12 ENST00000356527.9 ENST00000362052.7 ENST00000503345.1 ENST00000369014.10	ENSA Links Ensembl NCBI GeneCards UniProt Show fit	endosulfine alpha
chr20_+_2840694 Show fit	0.25	ENST00000380469.7 ENST00000380445.8 ENST00000453689.5 ENST00000417508.1	VPS16 Links Ensembl NCBI GeneCards UniProt Show fit	VPS16 core subunit of CORVET and HOPS complexes
chr21_-_6467509 Show fit	0.25	ENST00000624406.3 ENST00000398168.5 ENST00000624934.3	CBSL Links Ensembl NCBI GeneCards UniProt Show fit	cystathionine beta-synthase like
chr5_-_146182591 Show fit	0.25	ENST00000510191.5 ENST00000674277.1 ENST00000674447.1 ENST00000674270.1 ENST00000394434.7 ENST00000674290.1 ENST00000674398.1 ENST00000674174.1	LARS1 Links Ensembl NCBI GeneCards UniProt Show fit	leucyl-tRNA synthetase 1
chr10_-_35090545 Show fit	0.25	ENST00000374751.7 ENST00000626172.2	CUL2 Links Ensembl NCBI GeneCards UniProt Show fit	cullin 2
chr15_-_72117712 Show fit	0.24	ENST00000444904.5 ENST00000564571.5	MYO9A Links Ensembl NCBI GeneCards UniProt Show fit	myosin IXA
chr7_+_48924559 Show fit	0.24	ENST00000650262.1	CDC14C Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14C
chr16_-_70289480 Show fit	0.24	ENST00000261772.13 ENST00000675953.1 ENST00000675691.1 ENST00000675133.1 ENST00000674512.1 ENST00000675045.1 ENST00000675853.1 ENST00000565361.3 ENST00000674963.1 ENST00000674691.1	AARS1 Links Ensembl NCBI GeneCards UniProt Show fit	alanyl-tRNA synthetase 1
chr1_+_28887166 Show fit	0.23	ENST00000347529.7	EPB41 Links Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1
chr12_+_57230336 Show fit	0.22	ENST00000555773.5 ENST00000554975.5 ENST00000449049.7	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr11_-_128867268 Show fit	0.22	ENST00000392665.6 ENST00000392666.6	KCNJ1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 1
chr2_+_113127588 Show fit	0.22	ENST00000409930.4	IL1RN Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor antagonist
chr21_-_44914271 Show fit	0.22	ENST00000522931.5	ITGB2 Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr12_+_57230301 Show fit	0.21	ENST00000553474.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr17_-_79839387 Show fit	0.21	ENST00000448310.1 ENST00000269397.9	CBX4 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 4
chr2_+_226835936 Show fit	0.20	ENST00000341329.7 ENST00000437454.5 ENST00000443477.5 ENST00000423616.1 ENST00000392062.7 ENST00000448992.5	RHBDD1 Links Ensembl NCBI GeneCards UniProt Show fit	rhomboid domain containing 1
chr11_-_128867364 Show fit	0.20	ENST00000440599.6 ENST00000324036.7	KCNJ1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 1
chr7_-_48029102 Show fit	0.19	ENST00000297325.9 ENST00000412142.5 ENST00000395572.6	SUN3 Links Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 3
chr19_-_35513641 Show fit	0.19	ENST00000339686.8 ENST00000447113.6	DMKN Links Ensembl NCBI GeneCards UniProt Show fit	dermokine
chr15_-_82571741 Show fit	0.18	ENST00000562833.2 ENST00000611163.4	ENSG00000260836.2 Links Ensembl NCBI GeneCards UniProt Show fit CPEB1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein cytoplasmic polyadenylation element binding protein 1
chr11_+_119085200 Show fit	0.18	ENST00000650101.1	HMBS Links Ensembl NCBI GeneCards UniProt Show fit	hydroxymethylbilane synthase
chr1_-_19923617 Show fit	0.18	ENST00000375116.3	PLA2G2E Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IIE
chr9_+_127264740 Show fit	0.17	ENST00000373387.9	GARNL3 Links Ensembl NCBI GeneCards UniProt Show fit	GTPase activating Rap/RanGAP domain like 3
chr3_+_12351470 Show fit	0.17	ENST00000287820.10	PPARG Links Ensembl NCBI GeneCards UniProt Show fit	peroxisome proliferator activated receptor gamma
chr5_-_35230467 Show fit	0.16	ENST00000515839.1 ENST00000618457.5	PRLR Links Ensembl NCBI GeneCards UniProt Show fit	prolactin receptor
chr10_+_95755652 Show fit	0.16	ENST00000371207.8	ENTPD1 Links Ensembl NCBI GeneCards UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 1
chr1_+_111473792 Show fit	0.15	ENST00000343534.9	C1orf162 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 162
chr12_+_57230086 Show fit	0.15	ENST00000414700.7 ENST00000557703.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr11_-_12009082 Show fit	0.14	ENST00000396505.7	DKK3 Links Ensembl NCBI GeneCards UniProt Show fit	dickkopf WNT signaling pathway inhibitor 3
chr1_+_111473972 Show fit	0.14	ENST00000369718.4	C1orf162 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 162
chr2_+_240868817 Show fit	0.14	ENST00000307503.4	AGXT Links Ensembl NCBI GeneCards UniProt Show fit	alanine--glyoxylate and serine--pyruvate aminotransferase
chr16_+_1309621 Show fit	0.14	ENST00000397515.6 ENST00000397514.8 ENST00000567383.6 ENST00000403747.6	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 I
chr17_-_35063648 Show fit	0.14	ENST00000394597.7	RFFL Links Ensembl NCBI GeneCards UniProt Show fit	ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr11_-_102724945 Show fit	0.13	ENST00000236826.8	MMP8 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 8
chr14_-_24576240 Show fit	0.13	ENST00000216336.3	CTSG Links Ensembl NCBI GeneCards UniProt Show fit	cathepsin G

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.9	27.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
3.7	11.1	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
3.2	9.5	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.1	3.3	GO:1905006	negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.9	4.7	GO:0032764	negative regulation of mast cell cytokine production(GO:0032764)
0.9	2.6	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.8	3.3	GO:1903803	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.8	3.2	GO:1904640	response to methionine(GO:1904640)
0.6	3.2	GO:0006868	glutamine transport(GO:0006868)
0.6	1.9	GO:1904692	positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.6	6.2	GO:0001554	luteolysis(GO:0001554)
0.5	1.5	GO:1904253	phthalate metabolic process(GO:0018963) positive regulation of bile acid biosynthetic process(GO:0070859) cellular response to luteinizing hormone stimulus(GO:0071373) positive regulation of bile acid metabolic process(GO:1904253)
0.5	1.9	GO:0032474	otolith morphogenesis(GO:0032474)
0.5	2.3	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4	3.4	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.4	1.6	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.4	1.5	GO:1903755	regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.4	1.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.4	0.7	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3	10.4	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.3	4.7	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.3	0.9	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.3	1.2	GO:0009257	10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.3	4.7	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3	0.8	GO:2000547	regulation of dendritic cell dendrite assembly(GO:2000547)
0.3	1.8	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.3	1.8	GO:0044245	polysaccharide digestion(GO:0044245)
0.3	2.6	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.3	1.5	GO:0060356	leucine import(GO:0060356)
0.2	4.0	GO:0072619	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2	1.3	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.2	1.0	GO:1902896	terminal web assembly(GO:1902896)
0.2	8.9	GO:0008053	mitochondrial fusion(GO:0008053)
0.2	0.8	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.2	9.6	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.2	4.3	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2	1.1	GO:0039019	pronephric nephron development(GO:0039019)
0.2	3.6	GO:0006751	glutathione catabolic process(GO:0006751)
0.2	1.6	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2	0.9	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.2	2.9	GO:0003322	pancreatic A cell development(GO:0003322)
0.2	1.2	GO:0044334	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.2	1.0	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	4.7	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.1	1.8	GO:0006449	regulation of translational termination(GO:0006449)
0.1	1.4	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	0.7	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1	0.8	GO:0051012	microtubule sliding(GO:0051012)
0.1	1.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1	2.6	GO:0007220	Notch receptor processing(GO:0007220)
0.1	0.6	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.1	1.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	2.7	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1	0.5	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.1	0.3	GO:0018160	peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1	9.3	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.1	0.5	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.1	0.4	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1	0.7	GO:0036093	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1	0.4	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1	0.4	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.1	0.4	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1	0.1	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	1.8	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	7.6	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1	3.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.7	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.1	1.5	GO:0097186	amelogenesis(GO:0097186)
0.1	0.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.6	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.2	GO:1903575	cornified envelope assembly(GO:1903575)
0.0	0.2	GO:1902612	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0	0.6	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	2.2	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.5	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	1.0	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.6	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.6	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	6.3	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.2	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0	0.5	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	3.7	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.2	GO:2000229	pancreatic stellate cell proliferation(GO:0072343) response to metformin(GO:1901558) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0	0.3	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.1	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.5	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0070942	neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0	1.0	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.2	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	3.8	GO:0006275	regulation of DNA replication(GO:0006275)
0.0	0.7	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.2	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770) negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.4	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0	0.7	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.7	GO:1990622	CHOP-ATF3 complex(GO:1990622)
1.2	9.6	GO:1990111	spermatoproteasome complex(GO:1990111)
0.7	4.7	GO:1990037	Lewy body core(GO:1990037)
0.6	1.8	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.6	2.3	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.4	1.5	GO:1990356	sumoylated E2 ligase complex(GO:1990356)
0.3	27.4	GO:0015030	Cajal body(GO:0015030)
0.3	2.6	GO:0070765	gamma-secretase complex(GO:0070765)
0.3	1.0	GO:0098592	microspike(GO:0044393) cytoplasmic side of apical plasma membrane(GO:0098592)
0.3	2.6	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	13.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	1.5	GO:0030061	mitochondrial crista(GO:0030061)
0.1	1.3	GO:0070552	BRISC complex(GO:0070552)
0.1	1.1	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.1	0.3	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1	11.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.5	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	1.2	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	1.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.5	GO:0089701	U2AF(GO:0089701)
0.1	1.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	3.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	8.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.4	GO:0097255	R2TP complex(GO:0097255)
0.0	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.0	7.0	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	2.4	GO:0005871	kinesin complex(GO:0005871)
0.0	0.7	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	3.0	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	8.4	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.2	GO:0030891	VCB complex(GO:0030891)
0.0	2.7	GO:0005657	replication fork(GO:0005657)
0.0	2.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.2	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.0	4.6	GO:0072562	blood microparticle(GO:0072562)
0.0	0.6	GO:0042101	T cell receptor complex(GO:0042101)
0.0	2.8	GO:0043679	axon terminus(GO:0043679)
0.0	10.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	1.8	GO:0005901	caveola(GO:0005901)
0.0	3.3	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.7	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	1.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.6	GO:0030686	90S preribosome(GO:0030686)
0.0	2.3	GO:0005903	brush border(GO:0005903)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.5	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	1.0	GO:0072686	mitotic spindle(GO:0072686)
0.0	1.4	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.5	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.1	27.4	GO:0008859	exoribonuclease II activity(GO:0008859)
1.5	7.7	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.9	3.6	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.8	6.5	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.8	4.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.5	3.3	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.5	3.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4	8.9	GO:0051400	BH domain binding(GO:0051400)
0.4	2.0	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.4	1.5	GO:0061656	SUMO conjugating enzyme activity(GO:0061656)
0.4	6.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.4	1.1	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3	9.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	2.6	GO:0070728	leucine binding(GO:0070728)
0.3	0.9	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.3	1.8	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.3	2.3	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3	1.2	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)
0.2	1.8	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2	1.3	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	0.9	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.2	0.5	GO:0032427	GBD domain binding(GO:0032427)
0.2	2.7	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	1.8	GO:0004568	chitinase activity(GO:0004568)
0.1	1.6	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	1.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	6.6	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	0.8	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.6	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.7	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	3.9	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.7	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	1.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.3	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	15.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.3	GO:0004418	hydroxymethylbilane synthase activity(GO:0004418)
0.1	1.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	1.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	0.9	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.5	GO:0004122	cystathionine beta-synthase activity(GO:0004122)
0.1	1.5	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	1.8	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.7	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.5	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	0.4	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.1	0.2	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	1.5	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	0.3	GO:0004925	prolactin receptor activity(GO:0004925)
0.1	2.1	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	3.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	5.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	0.4	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	20.9	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	1.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.7	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	1.0	GO:0044548	S100 protein binding(GO:0044548)
0.1	2.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	2.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	1.4	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	2.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	4.6	GO:0043621	protein self-association(GO:0043621)
0.0	0.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	1.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	1.4	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	1.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	1.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	3.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.5	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	2.4	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.6	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	1.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	1.0	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	1.3	GO:0043022	ribosome binding(GO:0043022)
0.0	2.1	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	1.6	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.4	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.8	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	1.9	GO:0044325	ion channel binding(GO:0044325)
0.0	0.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	10.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	12.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	2.9	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	8.9	PID BCR 5PATHWAY	BCR signaling pathway
0.1	0.9	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	5.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	2.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	1.2	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	2.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.7	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.0	PID RHOA PATHWAY	RhoA signaling pathway
0.0	2.9	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	3.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	4.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	16.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.4	10.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	19.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	30.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	2.6	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	4.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	7.8	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	2.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	2.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	3.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	2.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.8	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	1.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.7	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	2.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.9	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS