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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for CLOCK

Z-value: 0.89

Motif logo

Transcription factors associated with CLOCK

Gene Symbol Gene ID Gene Info
ENSG00000134852.15 CLOCK

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CLOCKhg38_v1_chr4_-_55546900_555469190.281.8e-01Click!

Activity profile of CLOCK motif

Sorted Z-values of CLOCK motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CLOCK

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_185396834 1.80 ENST00000335174.6
ankyrin repeat domain 37
chr7_+_1055285 1.57 ENST00000397095.2
G protein-coupled receptor 146
chr14_+_32934383 1.48 ENST00000551634.6
neuronal PAS domain protein 3
chr4_+_89111521 1.38 ENST00000603357.3
tigger transposable element derived 2
chr21_-_30497160 1.23 ENST00000334058.3
keratin associated protein 19-4
chr9_+_706841 1.22 ENST00000382293.7
KN motif and ankyrin repeat domains 1
chr10_-_49539015 1.21 ENST00000681659.1
ENST00000680107.1
ERCC excision repair 6, chromatin remodeling factor
chr10_-_49539112 1.19 ENST00000355832.10
ENST00000447839.7
ERCC excision repair 6, chromatin remodeling factor
chr5_+_136058849 1.16 ENST00000508076.5
transforming growth factor beta induced
chr3_-_122793772 1.03 ENST00000306103.3
HSPB1 associated protein 1
chr2_-_105396943 0.98 ENST00000409807.5
four and a half LIM domains 2
chr19_+_45498439 0.95 ENST00000451287.7
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr4_-_18021727 0.94 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr9_+_114611206 0.92 ENST00000374049.4
ENST00000288502.9
transmembrane protein 268
chr4_+_128811264 0.88 ENST00000610919.4
ENST00000510308.5
jade family PHD finger 1
chr15_+_49155750 0.87 ENST00000327171.7
ENST00000560654.5
galactokinase 2
chr12_+_64404338 0.87 ENST00000332707.10
exportin for tRNA
chr11_-_19240936 0.86 ENST00000250024.9
E2F transcription factor 8
chr19_+_45499797 0.85 ENST00000401593.5
ENST00000396736.2
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr19_+_45499610 0.84 ENST00000396735.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr1_+_152663378 0.83 ENST00000368784.2
late cornified envelope 2D
chr2_-_224402097 0.82 ENST00000409685.4
family with sequence similarity 124 member B
chr16_+_53054973 0.82 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr8_+_94895763 0.82 ENST00000523378.5
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr6_-_111606260 0.81 ENST00000340026.10
TRAF3 interacting protein 2
chr1_-_231241090 0.81 ENST00000451322.1
chromosome 1 open reading frame 131
chr15_+_97960692 0.77 ENST00000268042.7
arrestin domain containing 4
chr2_-_224401994 0.77 ENST00000389874.3
family with sequence similarity 124 member B
chr19_-_38869921 0.75 ENST00000593809.1
ENST00000593424.5
Ras and Rab interactor like
chr2_+_112645930 0.74 ENST00000272542.8
solute carrier family 20 member 1
chr9_-_131270493 0.72 ENST00000372269.7
ENST00000464831.1
family with sequence similarity 78 member A
chr9_-_6015607 0.72 ENST00000485372.1
ENST00000259569.6
ENST00000623170.1
RAN binding protein 6
chr1_+_150282526 0.71 ENST00000447007.5
ENST00000369095.5
ENST00000369094.5
ENST00000290363.6
circadian associated repressor of transcription
chr15_-_52652031 0.70 ENST00000546305.6
family with sequence similarity 214 member A
chr5_+_95731300 0.70 ENST00000379982.8
Rho related BTB domain containing 3
chr1_-_205775182 0.70 ENST00000446390.6
RAB29, member RAS oncogene family
chr17_+_32486975 0.68 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr6_-_6004040 0.68 ENST00000622188.4
neuritin 1
chr19_-_18884219 0.67 ENST00000596048.1
ceramide synthase 1
chrX_-_101932074 0.67 ENST00000651725.1
zinc finger matrin-type 1
chr14_+_39267377 0.66 ENST00000556148.5
ENST00000348007.7
MIA SH3 domain ER export factor 2
chr14_+_31561376 0.62 ENST00000550649.5
ENST00000281081.12
nucleotide binding protein like
chr2_-_171434763 0.60 ENST00000442778.5
ENST00000453846.5
ENST00000612742.5
methyltransferase like 8
chr5_-_103120097 0.60 ENST00000508629.5
ENST00000399004.7
gypsy retrotransposon integrase 1
chr10_-_78029487 0.60 ENST00000372371.8
RNA polymerase III subunit A
chr19_+_1071194 0.60 ENST00000543365.5
Rho GTPase activating protein 45
chr12_+_28190420 0.60 ENST00000539107.5
ENST00000545336.5
coiled-coil domain containing 91
chr7_-_103989516 0.59 ENST00000343529.9
ENST00000424685.3
reelin
chrX_+_51332805 0.59 ENST00000356450.3
nudix hydrolase 10
chr10_+_100997040 0.58 ENST00000370223.7
leucine zipper tumor suppressor 2
chr5_-_74641419 0.58 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr3_-_98593589 0.58 ENST00000647941.2
coproporphyrinogen oxidase
chr7_-_103989649 0.56 ENST00000428762.6
reelin
chr19_+_1275997 0.55 ENST00000469144.5
family with sequence similarity 174 member C
chr10_-_50623897 0.55 ENST00000361781.7
ENST00000429490.5
ENST00000619438.4
sphingomyelin synthase 1
chr8_+_94895837 0.54 ENST00000519136.5
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr17_+_57085714 0.54 ENST00000571629.5
ENST00000570423.5
ENST00000575186.5
ENST00000621116.4
ENST00000573085.1
ENST00000572814.1
A-kinase anchoring protein 1
chr3_-_168095885 0.53 ENST00000470487.6
golgi integral membrane protein 4
chr11_+_18394552 0.51 ENST00000543445.5
ENST00000430553.6
ENST00000396222.6
ENST00000535451.5
ENST00000422447.8
lactate dehydrogenase A
chr1_-_231241121 0.51 ENST00000318906.6
ENST00000366649.7
ENST00000366651.7
chromosome 1 open reading frame 131
chr16_+_66880503 0.51 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr2_+_215312028 0.50 ENST00000236959.14
ENST00000435675.5
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_-_7916280 0.50 ENST00000324348.9
ring finger protein 227
chr2_-_10448318 0.49 ENST00000234111.9
ornithine decarboxylase 1
chr2_-_148020754 0.49 ENST00000440042.1
ENST00000536575.5
origin recognition complex subunit 4
chr2_-_148020689 0.49 ENST00000457954.5
ENST00000392857.10
ENST00000540442.5
ENST00000535373.5
origin recognition complex subunit 4
chr8_-_109691590 0.49 ENST00000532779.5
ENST00000534578.5
syntabulin
chr19_+_1275508 0.48 ENST00000409293.6
family with sequence similarity 174 member C
chr13_+_50909745 0.48 ENST00000422660.6
ENST00000645188.1
ENST00000646731.1
ENST00000643774.1
ENST00000646960.1
ENST00000637648.2
ENST00000336617.8
ribonuclease H2 subunit B
chr22_+_18110305 0.48 ENST00000680175.1
ENST00000426208.5
tubulin alpha 8
chr2_+_148021001 0.48 ENST00000407073.5
methyl-CpG binding domain protein 5
chr2_+_200306648 0.48 ENST00000409140.8
spermatogenesis associated serine rich 2 like
chr12_+_64610458 0.48 ENST00000542104.6
Ras association domain family member 3
chr11_-_129947461 0.47 ENST00000526082.5
ENST00000304538.10
PR/SET domain 10
chr12_-_90955172 0.47 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr9_-_122213903 0.47 ENST00000464484.3
LIM homeobox 6
chr19_+_1067144 0.47 ENST00000313093.7
Rho GTPase activating protein 45
chr7_+_2244476 0.47 ENST00000397049.2
nudix hydrolase 1
chr11_+_18394586 0.46 ENST00000227157.8
ENST00000478970.6
ENST00000495052.5
lactate dehydrogenase A
chr2_+_172556039 0.46 ENST00000410055.5
ENST00000282077.8
pyruvate dehydrogenase kinase 1
chr2_+_148021083 0.46 ENST00000642680.2
methyl-CpG binding domain protein 5
chr4_-_53591477 0.46 ENST00000263925.8
ligand of numb-protein X 1
chr17_-_75289443 0.46 ENST00000375261.8
ENST00000580273.1
solute carrier family 25 member 19
chr2_-_68157470 0.46 ENST00000406245.6
ENST00000409164.1
ENST00000295121.11
WD repeat domain 92
chr9_+_37120560 0.46 ENST00000336755.10
ENST00000534928.5
ENST00000322831.6
zinc finger CCHC-type containing 7
chr2_+_200305976 0.46 ENST00000358677.9
spermatogenesis associated serine rich 2 like
chr13_+_50910018 0.46 ENST00000645990.1
ENST00000642995.1
ENST00000636524.2
ENST00000643159.1
ENST00000645618.1
ENST00000611510.5
ENST00000642454.1
ENST00000646709.1
ribonuclease H2 subunit B
chr8_-_109644766 0.46 ENST00000533065.5
ENST00000276646.14
syntabulin
chr17_-_75289212 0.45 ENST00000582778.1
ENST00000581988.5
ENST00000579207.5
ENST00000583332.5
ENST00000442286.6
ENST00000580151.5
ENST00000580994.5
ENST00000584438.1
ENST00000416858.7
ENST00000320362.7
solute carrier family 25 member 19
chr17_-_7915929 0.45 ENST00000635932.1
ENST00000640240.1
ring finger protein 227
chr11_-_129947576 0.45 ENST00000423662.6
PR/SET domain 10
chr5_+_110738983 0.45 ENST00000355943.8
ENST00000447245.6
solute carrier family 25 member 46
chr20_-_1002264 0.44 ENST00000400634.2
ENST00000217260.9
R-spondin 4
chr3_+_100492548 0.44 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr1_-_11926385 0.44 ENST00000616327.1
ENST00000376572.8
ENST00000376576.3
KIAA2013
chr8_-_109691766 0.44 ENST00000529190.5
ENST00000422135.5
syntabulin
chr8_+_42338454 0.43 ENST00000532157.5
ENST00000520008.5
DNA polymerase beta
chr13_-_36346736 0.43 ENST00000451493.5
spartin
chr3_+_126704202 0.43 ENST00000290913.8
ENST00000508789.5
coiled-coil-helix-coiled-coil-helix domain containing 6
chr11_-_107565717 0.43 ENST00000428149.7
ENST00000429370.5
ENST00000417449.6
alkB homolog 8, tRNA methyltransferase
chr12_-_49828394 0.42 ENST00000335999.7
NCK associated protein 5 like
chr2_+_200305873 0.42 ENST00000439084.5
ENST00000409718.5
spermatogenesis associated serine rich 2 like
chr19_+_13151975 0.41 ENST00000588173.1
immediate early response 2
chr2_+_200306519 0.41 ENST00000360760.9
spermatogenesis associated serine rich 2 like
chr20_-_51023081 0.41 ENST00000433903.5
ENST00000424171.5
ENST00000371571.5
ENST00000439216.5
potassium voltage-gated channel modifier subfamily G member 1
chr13_+_19633642 0.41 ENST00000361479.10
M-phase phosphoprotein 8
chr6_-_145735463 0.41 ENST00000435470.2
ENST00000638262.1
EPM2A glucan phosphatase, laforin
chr4_+_94757921 0.41 ENST00000515059.6
bone morphogenetic protein receptor type 1B
chr15_+_96332432 0.40 ENST00000559679.1
ENST00000394171.6
nuclear receptor subfamily 2 group F member 2
chr4_-_56435581 0.40 ENST00000264220.6
phosphoribosyl pyrophosphate amidotransferase
chr6_-_39725335 0.40 ENST00000538893.5
kinesin family member 6
chr8_-_143359924 0.40 ENST00000521193.5
ENST00000520950.5
DNA topoisomerase I mitochondrial
chr17_+_18039370 0.40 ENST00000268719.9
ENST00000376345.3
GID complex subunit 4 homolog
chr6_-_145735513 0.39 ENST00000367519.9
EPM2A glucan phosphatase, laforin
chr2_+_200306048 0.39 ENST00000409988.7
ENST00000409385.5
spermatogenesis associated serine rich 2 like
chr10_+_62374361 0.39 ENST00000395254.8
zinc finger protein 365
chr6_-_145735964 0.39 ENST00000640980.1
ENST00000639423.1
ENST00000611340.5
EPM2A glucan phosphatase, laforin
chr13_-_36346478 0.38 ENST00000494062.2
spartin
chr15_-_56245074 0.38 ENST00000674082.1
regulatory factor X7
chr1_+_214603173 0.38 ENST00000366955.8
centromere protein F
chr1_+_109621088 0.38 ENST00000369840.7
ENST00000358729.9
ENST00000476688.3
adenosine monophosphate deaminase 2
chr6_-_144064511 0.38 ENST00000626373.2
ENST00000628651.2
ENST00000626294.2
ENST00000437412.5
ENST00000444202.5
ENST00000626462.2
ENST00000627449.2
PLAG1 like zinc finger 1
chr1_+_109619827 0.38 ENST00000667949.2
ENST00000342115.8
ENST00000528667.7
adenosine monophosphate deaminase 2
chr4_-_87220603 0.37 ENST00000273963.10
kelch like family member 8
chr17_+_74737211 0.37 ENST00000392612.7
ENST00000392610.5
RAB37, member RAS oncogene family
chr22_+_18110802 0.37 ENST00000330423.8
tubulin alpha 8
chr2_+_61162185 0.37 ENST00000432605.3
ENST00000488469.4
chromosome 2 open reading frame 74
chr10_+_86654541 0.37 ENST00000241891.10
ENST00000372071.6
opsin 4
chr4_-_87220491 0.37 ENST00000425278.6
ENST00000498875.6
kelch like family member 8
chr1_-_205775449 0.37 ENST00000235932.8
ENST00000437324.6
ENST00000414729.1
ENST00000367139.8
RAB29, member RAS oncogene family
chr18_+_36297661 0.37 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr2_-_218166951 0.36 ENST00000295683.3
C-X-C motif chemokine receptor 1
chr1_+_61082702 0.36 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr8_-_143359967 0.36 ENST00000519148.5
DNA topoisomerase I mitochondrial
chr14_-_58427134 0.36 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr14_+_58427385 0.36 ENST00000354386.10
ENST00000619416.4
KIAA0586
chr19_-_36054224 0.35 ENST00000292894.2
THAP domain containing 8
chr12_+_52301833 0.35 ENST00000293525.5
keratin 86
chr8_+_94895813 0.35 ENST00000396113.5
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr6_-_83065770 0.35 ENST00000369747.8
ubiquitin protein ligase E3D
chr14_-_91060578 0.35 ENST00000418736.6
ENST00000614987.5
ribosomal protein S6 kinase A5
chr15_+_40239042 0.35 ENST00000558055.5
ENST00000455577.6
p21 (RAC1) activated kinase 6
chr5_-_108367860 0.35 ENST00000496714.2
F-box and leucine rich repeat protein 17
chr7_+_116672187 0.35 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr20_+_63293180 0.34 ENST00000358894.10
collagen type XX alpha 1 chain
chr15_+_40239420 0.34 ENST00000560346.5
p21 (RAC1) activated kinase 6
chr11_+_96389985 0.34 ENST00000332349.5
JRK like
chr1_+_156860815 0.34 ENST00000368196.7
neurotrophic receptor tyrosine kinase 1
chr14_+_58427425 0.34 ENST00000619722.5
ENST00000423743.7
KIAA0586
chr4_+_127781815 0.34 ENST00000508776.5
heat shock protein family A (Hsp70) member 4 like
chr1_+_156860886 0.34 ENST00000358660.3
ENST00000675461.1
neurotrophic receptor tyrosine kinase 1
chr10_-_119165542 0.34 ENST00000419372.5
ENST00000369131.8
ENST00000355697.7
sideroflexin 4
chr14_-_58427114 0.33 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr12_+_109098118 0.33 ENST00000336865.6
uracil DNA glycosylase
chr1_+_156860857 0.33 ENST00000524377.7
neurotrophic receptor tyrosine kinase 1
chr22_-_17258235 0.33 ENST00000649310.1
ENST00000649746.1
adenosine deaminase 2
chr21_-_26843012 0.33 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr1_+_966466 0.33 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
pleckstrin homology domain containing N1
chr12_+_56267674 0.33 ENST00000546544.5
ENST00000553234.1
coenzyme Q10A
chr1_+_28328994 0.33 ENST00000373842.9
ENST00000398997.2
mediator complex subunit 18
chr5_+_136059151 0.33 ENST00000503087.1
transforming growth factor beta induced
chr3_+_66220984 0.32 ENST00000354883.11
ENST00000336733.10
solute carrier family 25 member 26
chr13_+_50909905 0.32 ENST00000644034.1
ENST00000645955.1
ribonuclease H2 subunit B
chr21_-_26843063 0.32 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr10_+_17809337 0.32 ENST00000569591.3
mannose receptor C-type 1
chrX_-_72306891 0.32 ENST00000454225.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr6_-_79947541 0.32 ENST00000369816.5
ELOVL fatty acid elongase 4
chr14_-_58427489 0.32 ENST00000555593.5
translocase of inner mitochondrial membrane 9
chr7_+_105532164 0.31 ENST00000493041.5
ENST00000257700.7
RAD50 interactor 1
chr12_+_57229694 0.31 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
serine hydroxymethyltransferase 2
chr6_+_151239951 0.31 ENST00000402676.7
A-kinase anchoring protein 12
chr20_+_24949256 0.31 ENST00000480798.2
cystatin F
chr14_+_22226711 0.31 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr10_+_114821744 0.31 ENST00000369250.7
ENST00000369246.1
ENST00000369248.9
family with sequence similarity 160 member B1
chr9_+_128683645 0.31 ENST00000372692.8
SET nuclear proto-oncogene
chr12_-_48999363 0.31 ENST00000421952.3
dendrin
chr8_-_108443409 0.30 ENST00000678023.1
ENST00000679198.1
ENST00000678881.1
ENST00000677084.1
ENST00000676663.1
ENST00000677614.1
ENST00000677040.1
ENST00000676487.1
ENST00000677409.1
ENST00000678797.1
ENST00000678334.1
eukaryotic translation initiation factor 3 subunit E
chr7_-_122886439 0.30 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr4_-_185395882 0.30 ENST00000505916.6
LRP2 binding protein
chr6_-_34146080 0.30 ENST00000538487.7
ENST00000374181.8
glutamate metabotropic receptor 4
chr14_-_46651753 0.30 ENST00000298283.5
ribosomal protein L10 like
chr18_-_35497904 0.30 ENST00000590757.1
ENST00000592173.5
ENST00000441607.6
ENST00000334598.12
ENST00000587450.1
ENST00000589258.1
INO80 complex subunit C
novel protein
chr15_+_36579782 0.30 ENST00000437989.6
CDAN1 interacting nuclease 1
chr9_-_137028223 0.30 ENST00000341511.11
ATP binding cassette subfamily A member 2
chr11_-_90223036 0.30 ENST00000320585.11
cysteine and histidine rich domain containing 1
chr17_-_73092657 0.29 ENST00000580557.5
ENST00000579732.5
ENST00000578620.1
ENST00000542342.6
ENST00000255559.7
ENST00000579018.5
solute carrier family 39 member 11
chr9_-_137028271 0.29 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr2_+_200306340 0.29 ENST00000451764.6
spermatogenesis associated serine rich 2 like
chrX_+_52897306 0.29 ENST00000612188.4
ENST00000616419.4
ENST00000416841.7
ENST00000593751.7
family with sequence similarity 156 member B
chr20_-_21514046 0.29 ENST00000377142.5
NK2 homeobox 2
chr12_+_57230301 0.29 ENST00000553474.5
serine hydroxymethyltransferase 2
chrX_+_118974608 0.29 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr2_-_230219944 0.29 ENST00000455674.2
ENST00000392048.7
ENST00000258381.11
ENST00000358662.9
ENST00000258382.10
SP110 nuclear body protein
chr12_+_57230086 0.29 ENST00000414700.7
ENST00000557703.5
serine hydroxymethyltransferase 2
chr1_+_116754422 0.29 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr6_+_151240368 0.28 ENST00000253332.5
A-kinase anchoring protein 12
chr17_-_8156320 0.28 ENST00000584202.1
ENST00000354903.9
ENST00000577253.5
period circadian regulator 1
chr12_+_57230336 0.28 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
serine hydroxymethyltransferase 2
chr2_+_219253243 0.28 ENST00000490341.3
tubulin alpha 4b
chr11_+_43358908 0.28 ENST00000039989.9
ENST00000299240.10
tetratricopeptide repeat domain 17

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.3 1.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 0.9 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.3 0.9 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 1.0 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 0.7 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.7 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 2.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 1.0 GO:0021553 olfactory nerve development(GO:0021553)
0.2 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 0.9 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.4 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.9 GO:0071105 response to interleukin-11(GO:0071105)
0.1 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.4 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.4 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.3 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.9 GO:0006188 IMP biosynthetic process(GO:0006188) IMP salvage(GO:0032264)
0.1 0.5 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 1.0 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.6 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.5 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0030718 inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.1 0.5 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.1 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.1 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.5 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.2 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 0.3 GO:0046103 adenosine catabolic process(GO:0006154) hypoxanthine salvage(GO:0043103) inosine biosynthetic process(GO:0046103)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.1 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.8 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.6 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.4 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.3 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.5 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.8 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.2 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 2.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.2 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.0 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 3.1 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 1.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 1.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.2 GO:0070552 BRISC complex(GO:0070552)
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 1.4 GO:0097433 dense body(GO:0097433)
0.1 1.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.8 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.2 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.9 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0070685 macropinocytic cup(GO:0070685)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.9 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.0 GO:0000805 X chromosome(GO:0000805)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.3 0.9 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 1.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 0.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 1.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 1.0 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.2 1.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0044713 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.2 0.5 GO:0004639 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.5 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.6 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.3 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.9 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.9 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.0 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0001626 nociceptin receptor activity(GO:0001626)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.0 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0051184 cofactor transporter activity(GO:0051184)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions