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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for CREB3L1_CREB3

Z-value: 1.15

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
ENSG00000157613.11 CREB3L1
ENSG00000107175.12 CREB3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3hg38_v1_chr9_+_35732649_357326850.701.1e-04Click!
CREB3L1hg38_v1_chr11_+_46277648_462776860.443.0e-02Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_49527988 3.23 ENST00000270645.8
reticulocalbin 3
chr2_-_69387130 3.18 ENST00000674438.1
glutamine--fructose-6-phosphate transaminase 1
chr8_-_63026179 2.97 ENST00000677919.1
gamma-glutamyl hydrolase
chr6_+_116370938 2.46 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
dermatan sulfate epimerase
chr3_-_156555083 2.35 ENST00000265044.7
ENST00000476217.5
signal sequence receptor subunit 3
chr5_+_127517611 2.34 ENST00000296666.13
ENST00000442138.6
ENST00000512635.2
proline rich coiled-coil 1
chr2_-_69387188 2.18 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr6_-_89352706 2.08 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr2_-_69387241 2.07 ENST00000361060.5
glutamine--fructose-6-phosphate transaminase 1
chr12_-_104958268 1.87 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr12_+_112938523 1.80 ENST00000679483.1
ENST00000679493.1
2'-5'-oligoadenylate synthetase 3
chr9_+_98056694 1.79 ENST00000210444.6
N-acetylneuraminate synthase
chr22_+_38468036 1.71 ENST00000409006.3
ENST00000216014.9
KDEL endoplasmic reticulum protein retention receptor 3
chr19_+_38319807 1.61 ENST00000263372.5
potassium two pore domain channel subfamily K member 6
chr6_+_31948956 1.53 ENST00000483004.1
complement factor B
chr4_+_25234003 1.46 ENST00000264864.8
phosphatidylinositol 4-kinase type 2 beta
chr12_+_78036248 1.44 ENST00000644176.1
neuron navigator 3
chr9_-_99221897 1.36 ENST00000476832.2
ALG2 alpha-1,3/1,6-mannosyltransferase
chr5_+_134648772 1.20 ENST00000398844.7
ENST00000322887.8
SEC24 homolog A, COPII coat complex component
chr16_+_19113955 1.19 ENST00000381440.5
ENST00000564808.6
ENST00000568526.1
ITPRIP like 2
novel transcript
chr12_-_113471851 1.19 ENST00000261731.4
LIM homeobox 5
chr11_-_59615673 1.16 ENST00000263847.6
oxysterol binding protein
chr11_-_62832033 1.11 ENST00000377897.8
ENST00000394690.5
ENST00000294179.8
syntaxin 5
chr7_-_100896123 1.11 ENST00000428317.7
acetylcholinesterase (Cartwright blood group)
chr12_+_112938422 1.10 ENST00000680044.1
ENST00000680966.1
ENST00000548514.2
ENST00000681497.1
ENST00000551007.1
ENST00000228928.12
ENST00000680438.1
ENST00000681147.1
ENST00000679354.1
ENST00000681085.1
ENST00000680161.1
2'-5'-oligoadenylate synthetase 3
chr3_-_119240870 1.07 ENST00000467604.5
ENST00000393765.7
ENST00000491906.5
ENST00000475803.5
ENST00000479150.5
ENST00000470111.5
ENST00000459820.5
ENST00000459778.5
ENST00000359213.7
beta-1,4-galactosyltransferase 4
chr5_-_132227808 1.06 ENST00000401867.5
ENST00000379086.5
ENST00000379100.7
ENST00000418055.5
ENST00000453286.5
ENST00000360568.8
ENST00000379104.7
ENST00000166534.8
prolyl 4-hydroxylase subunit alpha 2
chr11_-_64878612 1.05 ENST00000320631.8
EH domain containing 1
chr6_-_100881281 1.04 ENST00000369143.2
ENST00000369162.7
ENST00000324723.10
ENST00000522650.5
activating signal cointegrator 1 complex subunit 3
chr6_+_138161932 1.04 ENST00000251691.5
ARFGEF family member 3
chr4_+_55395915 1.03 ENST00000506198.5
ENST00000381334.10
transmembrane protein 165
chr9_-_127715602 0.98 ENST00000456267.5
ENST00000414832.2
peptidyl-tRNA hydrolase 1 homolog
chr7_+_73433761 0.98 ENST00000344575.5
frizzled class receptor 9
chr2_+_27032938 0.97 ENST00000238788.14
ENST00000404032.7
transmembrane protein 214
chr3_+_133573637 0.91 ENST00000264993.8
CDV3 homolog
chr12_+_106955890 0.90 ENST00000280756.9
transmembrane protein 263
chr11_+_33258304 0.90 ENST00000531504.5
ENST00000456517.2
homeodomain interacting protein kinase 3
chr7_-_30026617 0.89 ENST00000222803.10
FKBP prolyl isomerase 14
chr1_+_148952341 0.88 ENST00000529945.2
phosphodiesterase 4D interacting protein
chr5_-_132227472 0.86 ENST00000428369.6
prolyl 4-hydroxylase subunit alpha 2
chr12_+_106955719 0.84 ENST00000548125.5
transmembrane protein 263
chr21_+_43719095 0.84 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr4_-_118836067 0.83 ENST00000280551.11
SEC24 homolog D, COPII coat complex component
chr12_-_122266425 0.82 ENST00000643696.1
ENST00000267199.9
VPS33A core subunit of CORVET and HOPS complexes
chr3_-_57597443 0.82 ENST00000463880.1
ADP ribosylation factor 4
chr19_-_40690629 0.81 ENST00000252891.8
NUMB like endocytic adaptor protein
chr19_-_40690553 0.79 ENST00000598779.5
NUMB like endocytic adaptor protein
chr1_+_148952120 0.78 ENST00000313431.13
phosphodiesterase 4D interacting protein
chr5_-_10761156 0.74 ENST00000432074.2
ENST00000230895.11
death associated protein
chr14_+_49620750 0.74 ENST00000305386.4
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr18_+_59139864 0.73 ENST00000509791.7
ENST00000587834.6
ENST00000588875.2
SEC11 homolog C, signal peptidase complex subunit
chr10_-_27155214 0.72 ENST00000477432.1
YME1 like 1 ATPase
chr19_-_4670331 0.70 ENST00000262947.8
ENST00000599630.1
myeloid derived growth factor
chr5_-_131797030 0.68 ENST00000615660.4
folliculin interacting protein 1
chr10_+_132537814 0.66 ENST00000368593.7
inositol polyphosphate-5-phosphatase A
chr3_-_108222362 0.66 ENST00000492106.1
intraflagellar transport 57
chr5_-_131796921 0.65 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr15_-_28532971 0.64 ENST00000525590.2
golgin A8 family member G
chr1_+_26432299 0.64 ENST00000427245.6
ENST00000236342.12
ENST00000525682.6
ENST00000526219.5
ENST00000374185.7
ENST00000360009.6
ENST00000533087.5
ENST00000531312.5
ENST00000525165.5
ENST00000525326.5
ENST00000525546.5
ENST00000436153.6
ENST00000530781.5
dehydrodolichyl diphosphate synthase subunit
chr1_-_64966284 0.64 ENST00000671929.1
ENST00000673046.1
ENST00000672247.1
Janus kinase 1
chr12_-_106247950 0.63 ENST00000378026.5
cytoskeleton associated protein 4
chr3_-_57597325 0.63 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ADP ribosylation factor 4
chr1_-_145859061 0.63 ENST00000393045.7
protein inhibitor of activated STAT 3
chr9_+_111631300 0.62 ENST00000313525.4
DnaJ heat shock protein family (Hsp40) member C25
chr16_+_57186281 0.62 ENST00000564435.5
ENST00000562959.1
ENST00000568505.6
ENST00000394420.9
ENST00000537866.5
ring finger and SPRY domain containing 1
chr1_-_145859043 0.62 ENST00000369298.5
protein inhibitor of activated STAT 3
chr16_+_56657924 0.61 ENST00000334350.7
metallothionein 1F
chr3_-_156555135 0.60 ENST00000467789.5
signal sequence receptor subunit 3
chr16_+_56608577 0.59 ENST00000245185.6
ENST00000561491.1
metallothionein 2A
chr1_-_64966488 0.59 ENST00000342505.5
ENST00000673254.1
Janus kinase 1
chr11_+_65525413 0.59 ENST00000527009.5
SCY1 like pseudokinase 1
chr15_+_22458903 0.58 ENST00000620691.4
golgin A6 family like 22
chr11_+_65525067 0.57 ENST00000525364.5
ENST00000270176.10
ENST00000420247.6
ENST00000533862.5
ENST00000524944.5
SCY1 like pseudokinase 1
chr1_-_100894818 0.57 ENST00000370114.8
exostosin like glycosyltransferase 2
chr1_-_100894775 0.56 ENST00000416479.1
ENST00000370113.7
exostosin like glycosyltransferase 2
chr5_+_177303768 0.56 ENST00000303204.9
ENST00000503216.5
PRELI domain containing 1
chr17_+_59565598 0.56 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr16_+_68264501 0.56 ENST00000618043.4
ENST00000219343.11
ENST00000566834.5
ENST00000566454.5
solute carrier family 7 member 6
chr1_+_162561504 0.56 ENST00000271469.7
ENST00000367926.8
UDP-N-acetylglucosamine pyrophosphorylase 1
chr6_-_7313146 0.55 ENST00000489567.5
ENST00000479365.5
ENST00000462112.1
ENST00000397511.6
ENST00000244763.9
ENST00000474597.5
ENST00000650389.1
signal sequence receptor subunit 1
chr4_+_128061336 0.53 ENST00000432347.6
La ribonucleoprotein 1B
chrX_-_8171267 0.53 ENST00000317103.5
variable charge X-linked 2
chr14_-_52695543 0.52 ENST00000395686.8
endoplasmic reticulum oxidoreductase 1 alpha
chr1_+_119368802 0.52 ENST00000361035.8
ENST00000419144.1
hydroxyacid oxidase 2
HAO2 intronic transcript 1
chr1_+_119368773 0.52 ENST00000457318.5
ENST00000622548.4
ENST00000325945.4
hydroxyacid oxidase 2
chr19_-_40218339 0.51 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr2_+_170929198 0.51 ENST00000234160.5
golgi reassembly stacking protein 2
chr10_-_88583304 0.51 ENST00000331772.9
renalase, FAD dependent amine oxidase
chr5_-_19988179 0.50 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
cadherin 18
chr12_-_53079363 0.50 ENST00000547837.5
ENST00000301463.9
SPRY domain containing 3
chr5_-_131796965 0.50 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr2_+_232697362 0.50 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr4_+_164754116 0.49 ENST00000507311.1
small integral membrane protein 31
chr16_-_11742739 0.49 ENST00000356957.7
ENST00000283033.10
thioredoxin domain containing 11
chr1_-_37690481 0.49 ENST00000464085.5
ENST00000358011.8
ENST00000461359.5
ENST00000486637.2
chromosome 1 open reading frame 109
chr10_+_119651372 0.48 ENST00000369085.8
BAG cochaperone 3
chr8_+_63168989 0.48 ENST00000619337.4
ENST00000621890.4
ENST00000613853.4
ENST00000621820.4
YTH N6-methyladenosine RNA binding protein 3
chr17_-_7234262 0.48 ENST00000575756.5
ENST00000575458.5
dishevelled segment polarity protein 2
chr11_-_6481304 0.47 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr16_+_56657999 0.47 ENST00000568475.1
metallothionein 1F
chr11_-_119057218 0.46 ENST00000652093.1
hypoxia up-regulated 1
chr19_-_48511793 0.45 ENST00000600059.6
lemur tyrosine kinase 3
chr3_-_108222383 0.45 ENST00000264538.4
intraflagellar transport 57
chr2_-_33599269 0.44 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
family with sequence similarity 98 member A
chr11_-_6481350 0.44 ENST00000423813.6
ENST00000614314.4
ADP ribosylation factor interacting protein 2
chr15_+_22459123 0.43 ENST00000622895.1
golgin A6 family like 22
chr10_-_109923428 0.43 ENST00000403138.6
ENST00000369683.5
ENST00000502935.6
ENST00000322238.12
X-prolyl aminopeptidase 1
chr4_+_164754045 0.42 ENST00000515485.5
small integral membrane protein 31
chr20_-_64107546 0.42 ENST00000684052.1
neuropeptides B and W receptor 2
chr3_-_49358320 0.40 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
glutathione peroxidase 1
chr17_+_18781250 0.40 ENST00000476139.5
trans-golgi network vesicle protein 23 homolog B
chr17_+_34980484 0.39 ENST00000585941.5
ENST00000378526.9
ENST00000262327.9
ENST00000592690.1
ENST00000585740.5
DNA ligase 3
chr11_-_119057185 0.39 ENST00000614668.4
ENST00000617285.5
hypoxia up-regulated 1
chr5_+_66144204 0.39 ENST00000612404.4
splicing regulatory glutamic acid and lysine rich protein 1
chrX_+_16123544 0.38 ENST00000380289.3
gastrin releasing peptide receptor
chr5_-_90529511 0.38 ENST00000500869.6
ENST00000315948.11
ENST00000509384.5
LysM domain containing 3
chr17_-_75405486 0.38 ENST00000392562.5
growth factor receptor bound protein 2
chr17_-_15563428 0.38 ENST00000584811.5
ENST00000419890.3
ENST00000518321.6
ENST00000438826.7
ENST00000225576.7
ENST00000428082.6
ENST00000522212.6
trans-golgi network vesicle protein 23 homolog C
TVP23C-CDRT4 readthrough
chr15_+_41660397 0.38 ENST00000219905.12
ENST00000566586.6
MAX dimerization protein MGA
chr7_+_100673823 0.37 ENST00000419828.5
ENST00000427895.5
G protein subunit beta 2
chr15_+_81296913 0.37 ENST00000394652.6
interleukin 16
chr9_+_99222258 0.37 ENST00000223641.5
SEC61 translocon subunit beta
chr12_+_52069967 0.37 ENST00000336854.9
ENST00000550604.1
ENST00000553049.5
ENST00000548915.1
autophagy related 101
chr12_-_62935117 0.37 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr10_+_119892692 0.36 ENST00000369075.8
SEC23 interacting protein
chr19_-_10231293 0.36 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr1_-_241357085 0.35 ENST00000366564.5
regulator of G protein signaling 7
chr11_-_119057105 0.35 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
hypoxia up-regulated 1
chr1_-_241357225 0.35 ENST00000366565.5
regulator of G protein signaling 7
chr17_-_63699730 0.35 ENST00000578061.5
LIM domain containing 2
chr3_-_194398354 0.35 ENST00000401815.1
glycoprotein V platelet
chr2_+_182716227 0.35 ENST00000680258.1
ENST00000680667.1
ENST00000264065.12
ENST00000616986.5
ENST00000679884.1
DnaJ heat shock protein family (Hsp40) member C10
chr12_-_122896066 0.35 ENST00000267202.7
ENST00000535765.5
VPS37B subunit of ESCRT-I
chr19_-_46661132 0.35 ENST00000410105.2
ENST00000391916.7
dishevelled binding antagonist of beta catenin 3
chrX_+_8465426 0.35 ENST00000381029.4
variable charge X-linked 3B
chr9_-_128275935 0.35 ENST00000610329.4
golgin A2
chr9_-_127715633 0.34 ENST00000335223.5
ENST00000416214.1
ENST00000543175.5
peptidyl-tRNA hydrolase 1 homolog
chr11_-_14499833 0.34 ENST00000249923.7
ENST00000529866.5
COPI coat complex subunit beta 1
chr7_+_39623547 0.34 ENST00000005257.7
RAS like proto-oncogene A
chr4_+_109815734 0.34 ENST00000226796.7
GAR1 ribonucleoprotein
chr8_+_22565655 0.34 ENST00000523965.5
sorbin and SH3 domain containing 3
chr2_-_120223371 0.34 ENST00000426077.3
transmembrane protein 185B
chr8_-_143541425 0.33 ENST00000262577.6
zinc finger CCCH-type containing 3
chr7_+_100673732 0.33 ENST00000303210.9
ENST00000436220.5
ENST00000424361.5
G protein subunit beta 2
chr4_-_110623051 0.33 ENST00000557119.2
ENST00000644743.1
paired like homeodomain 2
chr1_-_241357171 0.33 ENST00000440928.6
regulator of G protein signaling 7
chr11_+_6481473 0.33 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr19_-_45584810 0.33 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr4_+_109815503 0.33 ENST00000394631.7
GAR1 ribonucleoprotein
chr11_+_1870252 0.33 ENST00000612798.4
lymphocyte specific protein 1
chr11_-_14499803 0.33 ENST00000439561.7
ENST00000534234.5
COPI coat complex subunit beta 1
chr3_-_49358340 0.33 ENST00000419783.3
glutathione peroxidase 1
chr10_+_27155339 0.31 ENST00000375940.9
ENST00000342386.10
microtubule associated serine/threonine kinase like
chr3_+_50246888 0.31 ENST00000451956.1
G protein subunit alpha i2
chr1_-_13198130 0.31 ENST00000638454.1
PRAME family member 13
chr11_+_47408582 0.31 ENST00000531974.5
ENST00000362021.9
ENST00000531419.5
ENST00000531865.5
ENST00000354884.8
solute carrier family 39 member 13
chr13_+_50909983 0.31 ENST00000643682.1
ENST00000642721.1
ENST00000616907.2
ribonuclease H2 subunit B
chr8_-_70607654 0.30 ENST00000521425.5
translocation associated membrane protein 1
chr11_-_67639752 0.30 ENST00000335385.4
T-box transcription factor 10
chr11_+_118572373 0.30 ENST00000392859.7
ENST00000264028.5
ENST00000614498.4
ENST00000359415.8
ENST00000534182.2
archain 1
chr6_-_137494387 0.29 ENST00000367734.4
oligodendrocyte transcription factor 3
chr15_-_74695987 0.29 ENST00000563009.5
ENST00000568176.5
ENST00000566243.5
ENST00000566219.1
ENST00000426797.7
ENST00000315127.9
ENST00000566119.5
enhancer of mRNA decapping 3
chrX_-_6535118 0.29 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
variable charge X-linked 3A
chr4_-_67701113 0.29 ENST00000420827.2
ENST00000322244.10
ubiquitin like modifier activating enzyme 6
chr19_+_48954850 0.28 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BCL2 associated X, apoptosis regulator
chr6_+_42563981 0.28 ENST00000372899.6
ENST00000372901.2
ubiquitin protein ligase E3 component n-recognin 2
chr2_-_80304274 0.28 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr12_-_55927103 0.28 ENST00000398213.4
PYM homolog 1, exon junction complex associated factor
chr1_+_109090726 0.28 ENST00000338272.9
ENST00000651489.1
transmembrane protein 167B
chr20_+_45791978 0.28 ENST00000449078.5
ENST00000456939.5
deoxynucleotidyltransferase terminal interacting protein 1
chr16_+_84176067 0.28 ENST00000564928.1
dynein axonemal assembly factor 1
chr11_+_1870150 0.27 ENST00000429923.5
ENST00000418975.1
ENST00000406638.6
lymphocyte specific protein 1
chr20_+_23350755 0.27 ENST00000254998.3
nuclear transport factor 2 like export factor 1
chr10_-_43407769 0.27 ENST00000357065.8
heterogeneous nuclear ribonucleoprotein F
chr5_+_41904329 0.26 ENST00000381647.7
ENST00000612065.1
chromosome 5 open reading frame 51
chr19_+_14433284 0.26 ENST00000242783.11
protein kinase N1
chr4_-_82429402 0.26 ENST00000602300.5
heterogeneous nuclear ribonucleoprotein D like
chr17_+_6651745 0.26 ENST00000542475.3
chromosome 17 open reading frame 100
chr3_-_49358272 0.26 ENST00000419349.2
glutathione peroxidase 1
chr2_+_191678122 0.25 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr14_+_103529208 0.25 ENST00000299202.4
tRNA methyltransferase 61A
chr14_+_103529163 0.25 ENST00000389749.9
tRNA methyltransferase 61A
chr3_+_35679614 0.25 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr6_+_151452447 0.25 ENST00000367294.4
acidic residue methyltransferase 1
chr1_-_202927184 0.25 ENST00000367261.8
kelch like family member 12
chr1_-_160343235 0.25 ENST00000368069.7
ENST00000241704.8
ENST00000647683.1
ENST00000649787.1
COPI coat complex subunit alpha
chr20_+_45791930 0.25 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr7_-_73770258 0.24 ENST00000395145.3
claudin 3
chr15_-_74695936 0.24 ENST00000647659.1
ENST00000566828.5
enhancer of mRNA decapping 3
chr11_-_102705737 0.24 ENST00000260229.5
matrix metallopeptidase 27
chr8_+_22565236 0.24 ENST00000523900.5
sorbin and SH3 domain containing 3
chrX_-_153794356 0.23 ENST00000427365.6
ENST00000444450.5
ENST00000217901.10
ENST00000370093.5
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chr3_+_121835197 0.23 ENST00000273668.7
ENST00000451944.2
ELL associated factor 2
chr22_-_23751080 0.23 ENST00000341976.5
zinc finger protein 70
chr7_+_128739395 0.23 ENST00000479257.5
calumenin
chr3_+_19947316 0.23 ENST00000422242.1
RAB5A, member RAS oncogene family
chr1_-_42456006 0.22 ENST00000372565.8
zinc finger MYND-type containing 12
chr1_-_11848345 0.22 ENST00000376476.1
natriuretic peptide A
chr6_+_26204552 0.21 ENST00000615164.2
H4 clustered histone 5
chr12_-_93441886 0.21 ENST00000552442.1
ENST00000550657.1
ENST00000318066.7
ubiquitin conjugating enzyme E2 N

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.5 1.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.5 7.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 2.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.4 1.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 1.0 GO:1902905 positive regulation of fibril organization(GO:1902905)
0.3 1.0 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.3 1.2 GO:1903382 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.2 2.9 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 0.6 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.2 0.8 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 1.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.5 GO:0090166 Golgi disassembly(GO:0090166)
0.2 1.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 2.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.2 0.7 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 1.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.6 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 1.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 1.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.8 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.1 1.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 1.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.3 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:1901859 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 2.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.9 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 1.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.2 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 1.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.5 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.3 GO:0021764 amygdala development(GO:0021764)
0.1 0.2 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 1.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.7 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.9 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 1.3 GO:0050779 RNA destabilization(GO:0050779)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.2 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.5 GO:1902074 response to salt(GO:1902074)
0.0 0.1 GO:1901421 generation of catalytic spliceosome for second transesterification step(GO:0000350) positive regulation of response to alcohol(GO:1901421)
0.0 0.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 2.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.0 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 2.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 1.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.0 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 2.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.2 GO:0097413 Lewy body(GO:0097413)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 1.1 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.4 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.6 2.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 1.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.4 1.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 1.0 GO:0052853 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 1.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 1.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 1.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 1.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.6 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.8 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.2 1.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 2.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 1.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 3.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.5 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 1.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 2.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.7 GO:0042731 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.0 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.6 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 1.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.4 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.4 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.6 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0004450 isocitrate dehydrogenase activity(GO:0004448) isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.0 GO:0004878 complement component C5a receptor activity(GO:0004878)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 4.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 3.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 2.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction