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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for CUX1

Z-value: 0.91

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Transcription factors associated with CUX1

Gene Symbol Gene ID Gene Info
ENSG00000257923.12 CUX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX1hg38_v1_chr7_+_101817601_1018176420.349.8e-02Click!

Activity profile of CUX1 motif

Sorted Z-values of CUX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_114684612 1.54 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr19_+_39406831 1.52 ENST00000597629.3
ENST00000594442.2
ENST00000594045.2
ZFP36 ring finger protein
chr9_-_42129125 0.99 ENST00000617422.4
ENST00000612828.4
ENST00000341990.8
ENST00000377561.7
ENST00000276974.7
contactin associated protein family member 3B
chr6_-_110179623 0.94 ENST00000265601.7
ENST00000447287.5
ENST00000392589.6
ENST00000444391.5
WASP family member 1
chr6_-_110179702 0.94 ENST00000392587.6
WASP family member 1
chr19_+_34926892 0.90 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr6_-_110179995 0.89 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr10_-_118595637 0.87 ENST00000239032.4
prolactin releasing hormone receptor
chr16_+_55509006 0.86 ENST00000262134.10
lysophosphatidylcholine acyltransferase 2
chr10_-_124092445 0.86 ENST00000346248.7
carbohydrate sulfotransferase 15
chr9_+_2157647 0.86 ENST00000452193.5
ENST00000324954.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_91946989 0.86 ENST00000556154.5
fibulin 5
chr1_+_15305735 0.83 ENST00000375997.8
ENST00000524761.5
ENST00000375995.3
forkhead associated phosphopeptide binding domain 1
chrX_-_63755187 0.81 ENST00000635729.1
ENST00000623566.3
Cdc42 guanine nucleotide exchange factor 9
chr10_-_114684457 0.80 ENST00000392955.7
actin binding LIM protein 1
chr11_-_33892010 0.80 ENST00000257818.3
LIM domain only 2
chr12_-_42483958 0.80 ENST00000548696.6
ENST00000552240.6
prickle planar cell polarity protein 1
chr7_+_150514851 0.74 ENST00000313543.5
GTPase, IMAP family member 7
chr5_-_150155828 0.72 ENST00000261799.9
platelet derived growth factor receptor beta
chr7_-_99929620 0.69 ENST00000312891.3
gap junction protein gamma 3
chr8_-_141367276 0.68 ENST00000377741.4
G protein-coupled receptor 20
chr1_-_209806124 0.67 ENST00000367021.8
ENST00000542854.5
interferon regulatory factor 6
chr5_-_111758061 0.66 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr1_+_113979460 0.66 ENST00000320334.5
olfactomedin like 3
chr19_-_51372640 0.65 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr4_-_158159657 0.64 ENST00000590648.5
golgi associated kinase 1B
chr1_+_113979391 0.64 ENST00000393300.6
ENST00000369551.5
olfactomedin like 3
chr12_-_42484298 0.64 ENST00000640055.1
ENST00000639566.1
ENST00000455697.6
ENST00000639589.1
prickle planar cell polarity protein 1
chr8_+_97869040 0.63 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr7_+_74028066 0.62 ENST00000431562.5
ENST00000320492.11
ENST00000438906.5
elastin
chr17_+_73233202 0.61 ENST00000582793.1
chromosome 17 open reading frame 80
chr18_+_79863668 0.58 ENST00000316249.3
potassium voltage-gated channel modifier subfamily G member 2
chr7_+_150567347 0.57 ENST00000461940.5
GTPase, IMAP family member 4
chr2_-_168913277 0.57 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr15_-_42156590 0.56 ENST00000397272.7
phospholipase A2 group IVF
chr14_+_63204436 0.55 ENST00000316754.8
ras homolog family member J
chr2_-_166128004 0.55 ENST00000303395.9
ENST00000674923.1
ENST00000637988.1
ENST00000635776.1
sodium voltage-gated channel alpha subunit 1
chr4_-_137532452 0.54 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr14_+_63204859 0.53 ENST00000555125.1
ras homolog family member J
chr16_+_4795378 0.52 ENST00000588606.5
small integral membrane protein 22
chr3_-_39192584 0.52 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr1_+_48222685 0.52 ENST00000533824.5
ENST00000236495.9
ENST00000438567.7
solute carrier family 5 member 9
chrX_+_102712438 0.52 ENST00000486814.2
ENST00000535209.6
ENST00000543253.6
ENST00000332262.10
ENST00000483720.6
G protein-coupled receptor associated sorting protein 2
chr8_+_96584920 0.51 ENST00000521590.5
syndecan 2
chr5_-_135954962 0.51 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr11_+_59787067 0.51 ENST00000528805.1
syntaxin 3
chr14_+_75278820 0.51 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chrX_-_117973579 0.50 ENST00000371878.5
kelch like family member 13
chr2_+_89851723 0.50 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr4_+_89111521 0.50 ENST00000603357.3
tigger transposable element derived 2
chr7_+_130486324 0.49 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chrX_+_72069659 0.49 ENST00000631375.1
NHS like 2
chr7_+_130486171 0.48 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr14_+_20891385 0.48 ENST00000304639.4
ribonuclease A family member 3
chr21_-_30497160 0.46 ENST00000334058.3
keratin associated protein 19-4
chr2_-_89143133 0.46 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr17_-_27793716 0.46 ENST00000646938.1
nitric oxide synthase 2
chr15_-_70892412 0.45 ENST00000249861.9
THAP domain containing 10
chr3_-_64225436 0.44 ENST00000638394.2
prickle planar cell polarity protein 2
chr12_-_9115907 0.44 ENST00000318602.12
alpha-2-macroglobulin
chr3_+_39383337 0.44 ENST00000650617.1
ENST00000431510.1
ENST00000645630.1
solute carrier family 25 member 38
chr8_+_96493803 0.44 ENST00000518385.5
ENST00000302190.9
syndecan 2
chr22_+_35066136 0.43 ENST00000308700.6
ENST00000404699.7
intestine specific homeobox
chr2_-_79159747 0.43 ENST00000409839.7
ENST00000305165.3
ENST00000393878.5
ENST00000490901.2
regenerating family member 3 alpha
chr14_-_20802836 0.43 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr12_-_57767057 0.42 ENST00000228606.9
cytochrome P450 family 27 subfamily B member 1
chr3_+_134795248 0.42 ENST00000398015.8
EPH receptor B1
chr13_-_80341100 0.42 ENST00000377104.4
sprouty RTK signaling antagonist 2
chr14_-_20802402 0.42 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr2_+_74549026 0.41 ENST00000409429.5
docking protein 1
chr1_+_84408230 0.40 ENST00000370662.3
deoxyribonuclease 2 beta
chr6_+_85450033 0.40 ENST00000257770.8
ENST00000369646.7
5'-nucleotidase ecto
chr9_-_104928139 0.39 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ATP binding cassette subfamily A member 1
chr20_-_3712564 0.39 ENST00000344754.6
sialic acid binding Ig like lectin 1
chr17_+_49788672 0.39 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr14_-_22815856 0.39 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr1_+_151156627 0.39 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr14_-_91732059 0.38 ENST00000553329.5
ENST00000256343.8
cation channel sperm associated auxiliary subunit beta
chr11_+_118304881 0.38 ENST00000528600.1
CD3e molecule
chr18_+_59225492 0.38 ENST00000456142.3
ENST00000530323.1
gastrin releasing peptide
chr5_-_78985288 0.38 ENST00000264914.10
arylsulfatase B
chr12_+_12785652 0.38 ENST00000356591.5
apolipoprotein L domain containing 1
chr6_-_32224060 0.38 ENST00000375023.3
notch receptor 4
chr19_-_50968775 0.38 ENST00000391808.5
kallikrein related peptidase 6
chr19_+_49513353 0.37 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr5_+_141172637 0.37 ENST00000231137.6
protocadherin beta 7
chr14_-_22815801 0.37 ENST00000397532.9
solute carrier family 7 member 7
chr14_-_67488709 0.37 ENST00000554480.6
transmembrane protein 229B
chr19_+_44809053 0.37 ENST00000611077.5
basal cell adhesion molecule (Lutheran blood group)
chr8_+_11808417 0.37 ENST00000525954.5
farnesyl-diphosphate farnesyltransferase 1
chr10_-_75401746 0.37 ENST00000372524.5
zinc finger protein 503
chr10_-_124092390 0.37 ENST00000628426.1
carbohydrate sulfotransferase 15
chr19_+_55376818 0.37 ENST00000291934.4
transmembrane protein 190
chr2_-_189762755 0.36 ENST00000520350.1
ENST00000521630.1
ENST00000264151.10
ENST00000517895.5
O-sialoglycoprotein endopeptidase like 1
chr3_+_49803212 0.36 ENST00000333323.6
inka box actin regulator 1
chr17_+_8039106 0.36 ENST00000573359.1
arachidonate 15-lipoxygenase type B
chr11_+_118304721 0.36 ENST00000361763.9
CD3e molecule
chr2_+_96326204 0.36 ENST00000420728.1
ENST00000361124.5
ITPRIP like 1
chr20_+_31368594 0.35 ENST00000253381.3
defensin beta 118
chr19_+_47713412 0.34 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr12_-_91180365 0.34 ENST00000547937.5
decorin
chr12_-_57237090 0.34 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr10_+_92831153 0.34 ENST00000672817.1
exocyst complex component 6
chr16_-_28495519 0.34 ENST00000569430.7
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr2_-_74553934 0.34 ENST00000264094.8
ENST00000393937.6
ENST00000409986.5
lysyl oxidase like 3
chr10_-_14954018 0.33 ENST00000378241.5
ENST00000456122.1
ENST00000418843.5
ENST00000378249.5
ENST00000396817.6
ENST00000378255.5
ENST00000378254.5
ENST00000357717.6
ENST00000378258.5
ENST00000378246.6
ENST00000378278.7
DNA cross-link repair 1C
chr12_+_6946468 0.33 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr11_+_63681483 0.33 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr14_-_106875069 0.33 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr9_+_71911468 0.33 ENST00000377031.7
chromosome 9 open reading frame 85
chr20_+_21126074 0.33 ENST00000619189.5
kizuna centrosomal protein
chr4_-_154612635 0.33 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
fibrinogen gamma chain
chr3_+_141384790 0.32 ENST00000507722.5
zinc finger and BTB domain containing 38
chr2_+_233636502 0.32 ENST00000373445.1
UDP glucuronosyltransferase family 1 member A10
chr9_+_34653864 0.32 ENST00000556792.5
ENST00000318041.13
interleukin 11 receptor subunit alpha
chr19_-_47555856 0.32 ENST00000391901.7
ENST00000314121.8
zinc finger protein 541
chr20_+_21125981 0.32 ENST00000619574.4
kizuna centrosomal protein
chr14_+_104581141 0.32 ENST00000410013.1
chromosome 14 open reading frame 180
chr11_-_119340544 0.31 ENST00000530681.2
C1q and TNF related 5
chr11_-_124441158 0.31 ENST00000328064.2
olfactory receptor family 8 subfamily B member 8
chr1_+_241532121 0.31 ENST00000366558.7
kynurenine 3-monooxygenase
chr19_-_42423100 0.31 ENST00000597001.1
lipase E, hormone sensitive type
chr14_+_24232892 0.31 ENST00000420554.6
guanosine monophosphate reductase 2
chr8_-_109608055 0.31 ENST00000529690.5
syntabulin
chrX_+_130339886 0.31 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
solute carrier family 25 member 14
chr19_+_50649445 0.31 ENST00000425202.6
chromosome 19 open reading frame 81
chr2_-_151261839 0.31 ENST00000331426.6
RNA binding motif protein 43
chr14_+_24232921 0.31 ENST00000557854.5
ENST00000399440.7
ENST00000559104.5
ENST00000456667.7
guanosine monophosphate reductase 2
chr19_+_12751789 0.31 ENST00000553030.6
bestrophin 2
chr12_+_48106094 0.30 ENST00000546755.5
ENST00000549366.5
ENST00000642730.1
ENST00000552792.5
phosphofructokinase, muscle
chr13_+_102656933 0.30 ENST00000650757.1
tripeptidyl peptidase 2
chr17_-_64390852 0.30 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr15_-_30991595 0.30 ENST00000435680.6
myotubularin related protein 10
chr11_+_61816249 0.29 ENST00000257261.10
fatty acid desaturase 2
chrX_+_102712471 0.29 ENST00000652409.1
ARMCX5-GPRASP2 readthrough
chr19_+_54630960 0.29 ENST00000396317.5
ENST00000396315.5
leukocyte immunoglobulin like receptor B1
chr1_+_212035717 0.29 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr13_-_44474296 0.29 ENST00000611198.4
TSC22 domain family member 1
chr16_+_32066065 0.28 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr8_+_22059198 0.28 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chr7_+_74773962 0.27 ENST00000289473.10
neutrophil cytosolic factor 1
chr11_-_119340816 0.27 ENST00000528368.3
C1q and TNF related 5
chr12_+_51238854 0.27 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr22_+_50089879 0.27 ENST00000545383.5
ENST00000262794.10
Mov10 like RISC complex RNA helicase 1
chr1_-_151372683 0.27 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
selenium binding protein 1
chr9_+_22446808 0.27 ENST00000325870.3
DMRT like family A1
chr9_+_27109393 0.27 ENST00000406359.8
TEK receptor tyrosine kinase
chr11_+_827545 0.27 ENST00000528542.6
calcium release activated channel regulator 2B
chr5_-_163460048 0.27 ENST00000517501.1
NudC domain containing 2
chr18_-_55402187 0.27 ENST00000630268.2
ENST00000570177.6
transcription factor 4
chr14_+_91114431 0.27 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr19_-_57974527 0.27 ENST00000314391.3
chromosome 19 open reading frame 18
chr9_-_34710069 0.27 ENST00000378792.1
ENST00000259607.7
C-C motif chemokine ligand 21
chrX_+_87517784 0.27 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr12_+_20695553 0.27 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr9_-_34376878 0.26 ENST00000297625.8
myogenesis regulating glycosidase (putative)
chr19_-_51020154 0.26 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chrX_+_55000329 0.26 ENST00000374987.4
apurinic/apyrimidinic endodeoxyribonuclease 2
chr11_-_63015804 0.26 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chr11_+_123430259 0.26 ENST00000533341.3
ENST00000635736.2
GRAM domain containing 1B
chr15_+_40239857 0.26 ENST00000260404.8
p21 (RAC1) activated kinase 6
chr11_+_9573633 0.26 ENST00000450114.7
WEE1 G2 checkpoint kinase
chr11_+_63681573 0.26 ENST00000354497.4
reticulon 3
chr9_+_126326809 0.26 ENST00000361171.8
ENST00000489637.3
multivesicular body subunit 12B
chr17_-_37359076 0.26 ENST00000621960.1
ENST00000614428.4
ENST00000614789.4
acetyl-CoA carboxylase alpha
chr14_+_23372809 0.25 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr8_+_22580496 0.25 ENST00000409417.5
PDZ and LIM domain 2
chr17_+_80423520 0.25 ENST00000521634.5
ENST00000572886.1
endonuclease V
chr14_-_106185387 0.25 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr5_+_148312416 0.25 ENST00000274565.5
serine peptidase inhibitor Kazal type 7
chr2_-_27663594 0.25 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SPT7 like, STAGA complex subunit gamma
chr20_+_32010429 0.25 ENST00000452892.3
ENST00000262659.12
CCM2 like scaffold protein
chr18_-_2571471 0.25 ENST00000574676.1
ENST00000574538.2
ENST00000319888.10
methyltransferase like 4
chr2_+_87338511 0.25 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr21_-_32728030 0.25 ENST00000382499.7
ENST00000433931.7
ENST00000382491.7
synaptojanin 1
chr4_+_107989880 0.25 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
hydroxyacyl-CoA dehydrogenase
chr11_-_31509569 0.24 ENST00000526776.5
inner mitochondrial membrane peptidase subunit 1
chr6_+_37005630 0.24 ENST00000274963.13
FYVE, RhoGEF and PH domain containing 2
chr22_-_37188233 0.24 ENST00000434784.1
ENST00000337843.7
C1q and TNF related 6
chrX_-_142205260 0.24 ENST00000247452.4
MAGE family member C2
chr6_-_41941507 0.24 ENST00000372987.8
cyclin D3
chr19_+_49513154 0.24 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
Fc fragment of IgG receptor and transporter
chr17_+_69502397 0.24 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr19_-_51082883 0.24 ENST00000650543.2
kallikrein related peptidase 14
chrX_-_100874209 0.24 ENST00000372964.5
ENST00000217885.5
NADPH oxidase 1
chr8_-_85341705 0.24 ENST00000517618.5
carbonic anhydrase 1
chrX_+_130339941 0.24 ENST00000218197.9
solute carrier family 25 member 14
chr5_-_163460067 0.24 ENST00000302764.9
NudC domain containing 2
chr2_+_60756226 0.24 ENST00000238714.8
poly(A) polymerase gamma
chr1_+_153031195 0.24 ENST00000307098.5
small proline rich protein 1B
chr1_+_241532370 0.23 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr17_+_20579724 0.23 ENST00000661883.1
ENST00000399044.1
CMT1A duplicated region transcript 15 like 2
chr2_+_178320228 0.23 ENST00000315022.2
oxysterol binding protein like 6
chr6_+_26103922 0.23 ENST00000377803.4
H4 clustered histone 3
chr2_+_188974364 0.23 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr1_+_161663147 0.23 ENST00000236937.13
ENST00000367961.8
ENST00000358671.9
Fc fragment of IgG receptor IIb
chr21_-_32727889 0.23 ENST00000630077.3
ENST00000674204.1
synaptojanin 1
chr2_-_44361485 0.23 ENST00000438314.1
ENST00000409411.6
ENST00000409936.5
prolyl endopeptidase like
chr19_-_43205551 0.23 ENST00000599391.1
ENST00000244295.13
ENST00000596907.5
ENST00000405312.8
ENST00000451895.1
ENST00000433626.6
pregnancy specific beta-1-glycoprotein 4
chr11_-_625168 0.23 ENST00000349570.11
cadherin related family member 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.3 2.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.4 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.7 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.2 0.9 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.2 0.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.2 0.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.6 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.6 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 0.7 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 1.0 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0036233 glycine import(GO:0036233)
0.1 0.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.7 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.4 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.5 GO:1903610 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.1 0.4 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.4 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.1 0.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0001796 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 0.4 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.3 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.4 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0019075 virus maturation(GO:0019075)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.7 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:2000078 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0060179 male mating behavior(GO:0060179)
0.0 0.5 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 1.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.7 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0032900 viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.5 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.6 GO:0008347 glial cell migration(GO:0008347)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0032225 regulation of synaptic transmission, dopaminergic(GO:0032225)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.4 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 GO:0031209 SCAR complex(GO:0031209)
0.2 1.5 GO:0071953 elastic fiber(GO:0071953)
0.2 0.5 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 1.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 1.5 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.5 GO:0071546 pi-body(GO:0071546)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 2.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0031095 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.8 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.4 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.7 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.4 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.5 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.1 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.3 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.3 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.7 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 3.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0016422 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.1 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 1.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins