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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for CUX2

Z-value: 1.14

Motif logo

Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
ENSG00000111249.14 CUX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX2hg38_v1_chr12_+_111034136_1110341730.301.5e-01Click!

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_93148345 5.14 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr21_+_41420515 5.12 ENST00000398600.6
ENST00000679626.1
MX dynamin like GTPase 1
chr6_-_159745186 4.69 ENST00000537657.5
superoxide dismutase 2
chr21_+_41426031 3.55 ENST00000455164.6
ENST00000681849.1
ENST00000679705.1
ENST00000424365.6
MX dynamin like GTPase 1
chr11_-_102780620 3.29 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr3_-_79019444 3.15 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
roundabout guidance receptor 1
chr6_+_127577168 3.02 ENST00000329722.8
chromosome 6 open reading frame 58
chr10_+_94683771 2.80 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr22_-_36160773 2.66 ENST00000531095.1
ENST00000349314.6
ENST00000397293.6
apolipoprotein L3
chr8_+_53851786 1.98 ENST00000297313.8
ENST00000344277.10
regulator of G protein signaling 20
chr9_+_5510492 1.97 ENST00000397747.5
programmed cell death 1 ligand 2
chr12_+_112906777 1.86 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr4_-_69961007 1.82 ENST00000353151.3
casein beta
chr21_+_42199686 1.82 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr15_-_35085295 1.76 ENST00000528386.4
Nanog homeobox retrogene P8
chr2_+_102418642 1.69 ENST00000264260.6
interleukin 18 receptor accessory protein
chr2_+_102337148 1.60 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr6_-_11778781 1.59 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr17_-_1229706 1.56 ENST00000574139.7
ABR activator of RhoGEF and GTPase
chr4_-_69214743 1.56 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr2_-_219399981 1.47 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr1_-_23014024 1.41 ENST00000440767.2
ENST00000622840.1
testis expressed 46
chr3_-_112975018 1.40 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr16_-_28623560 1.39 ENST00000350842.8
sulfotransferase family 1A member 1
chr2_+_101839815 1.33 ENST00000421882.5
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_154627945 1.32 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr18_-_36122110 1.28 ENST00000586829.1
solute carrier family 39 member 6
chr10_+_112376193 1.25 ENST00000433418.6
ENST00000356116.6
ENST00000354273.5
acyl-CoA synthetase long chain family member 5
chr4_-_68670648 1.22 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr5_-_116574802 1.17 ENST00000343348.11
semaphorin 6A
chr19_-_4535221 1.16 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr2_+_27032938 1.13 ENST00000238788.14
ENST00000404032.7
transmembrane protein 214
chr1_-_89126066 1.12 ENST00000370466.4
guanylate binding protein 2
chr10_+_112375196 1.08 ENST00000393081.6
acyl-CoA synthetase long chain family member 5
chr6_+_29100609 1.03 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr8_-_61646807 0.99 ENST00000522919.5
aspartate beta-hydroxylase
chr19_+_44946043 0.99 ENST00000252490.7
ENST00000591597.5
apolipoprotein C2
chr12_+_26195313 0.98 ENST00000422622.3
sarcospan
chr7_-_80919017 0.97 ENST00000265361.8
semaphorin 3C
chr17_-_69150062 0.97 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr1_-_89270751 0.95 ENST00000370459.7
guanylate binding protein 5
chrX_+_9463272 0.95 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr2_-_160493799 0.93 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr11_+_82901698 0.93 ENST00000524921.5
ENST00000528759.5
ENST00000525361.5
ENST00000532764.5
ENST00000532589.5
ENST00000533655.6
ENST00000525388.5
DNA damage induced apoptosis suppressor
chr17_-_69268812 0.93 ENST00000586811.1
ATP binding cassette subfamily A member 5
chr12_-_70788914 0.92 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr9_+_94084458 0.92 ENST00000620992.5
ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr11_-_57410113 0.92 ENST00000529411.1
novel protein
chr14_+_22070548 0.91 ENST00000390450.3
T cell receptor alpha variable 22
chr22_-_30246739 0.91 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr5_-_59586393 0.91 ENST00000505453.1
ENST00000360047.9
phosphodiesterase 4D
chr10_-_119536533 0.89 ENST00000392865.5
regulator of G protein signaling 10
chr13_+_38349822 0.87 ENST00000379649.5
ENST00000239878.9
ubiquitin fold modifier 1
chr11_+_62856149 0.87 ENST00000535296.5
solute carrier family 3 member 2
chr8_+_18391276 0.87 ENST00000286479.4
ENST00000520116.1
N-acetyltransferase 2
chr2_-_24328113 0.86 ENST00000622089.4
intersectin 2
chr12_+_6724008 0.86 ENST00000626119.2
ENST00000543155.6
COP9 signalosome subunit 7A
chr6_-_33580229 0.85 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr11_-_35419213 0.85 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
solute carrier family 1 member 2
chr12_-_91179355 0.85 ENST00000550563.5
ENST00000546370.5
decorin
chr1_+_146949314 0.85 ENST00000617844.4
ENST00000611443.4
NBPF member 12
chr12_-_21775581 0.84 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr12_-_89526253 0.83 ENST00000547474.1
POC1B-GALNT4 readthrough
chr15_-_88546585 0.83 ENST00000649547.1
ENST00000558413.1
ENST00000564406.5
ENST00000268148.13
novel transcript
DET1 partner of COP1 E3 ubiquitin ligase
chr6_+_46793379 0.80 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr12_-_86838867 0.79 ENST00000621808.4
MGAT4 family member C
chr1_+_111230725 0.78 ENST00000533831.6
chitinase 3 like 2
chr17_+_7558296 0.78 ENST00000438470.5
ENST00000436057.5
TNF superfamily member 13
chr14_-_23551729 0.78 ENST00000419474.5
zinc finger homeobox 2
chr12_-_89526164 0.77 ENST00000548729.5
POC1B-GALNT4 readthrough
chr19_-_46784733 0.76 ENST00000593713.1
ENST00000598022.1
ENST00000434726.6
solute carrier family 1 member 5
chrX_-_11265975 0.76 ENST00000303025.10
ENST00000657361.1
Rho GTPase activating protein 6
chr11_-_58844484 0.76 ENST00000532258.1
glycine-N-acyltransferase like 2
chr9_+_72114595 0.76 ENST00000545168.5
guanine deaminase
chr7_+_43112593 0.75 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr5_+_126423363 0.75 ENST00000285689.8
GRAM domain containing 2B
chr10_+_68109433 0.74 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr17_-_41369807 0.73 ENST00000251646.8
keratin 33B
chr8_-_86743626 0.71 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr5_-_146922515 0.71 ENST00000508545.6
protein phosphatase 2 regulatory subunit Bbeta
chr4_+_69280472 0.71 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr12_+_75334675 0.70 ENST00000312442.2
GLIPR1 like 1
chr8_+_103880412 0.70 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chrX_+_1268807 0.70 ENST00000381524.8
ENST00000381529.9
ENST00000412290.6
colony stimulating factor 2 receptor subunit alpha
chr15_+_64387828 0.70 ENST00000261884.8
thyroid hormone receptor interactor 4
chr11_-_55936400 0.70 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr15_+_84980440 0.70 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr8_-_133060347 0.69 ENST00000427060.6
Src like adaptor
chr17_-_41168219 0.69 ENST00000391356.4
keratin associated protein 4-3
chr12_-_89526011 0.68 ENST00000313546.8
POC1 centriolar protein B
chr21_+_18244828 0.68 ENST00000299295.7
chondrolectin
chr20_-_59940289 0.68 ENST00000370996.5
protein phosphatase 1 regulatory subunit 3D
chr13_-_46182136 0.68 ENST00000323076.7
lymphocyte cytosolic protein 1
chr2_-_151973780 0.67 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
calcium voltage-gated channel auxiliary subunit beta 4
chr4_+_109815503 0.67 ENST00000394631.7
GAR1 ribonucleoprotein
chr1_-_151831768 0.67 ENST00000318247.7
RAR related orphan receptor C
chr2_+_105851748 0.66 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr5_+_151771884 0.66 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr4_-_48080172 0.66 ENST00000507351.1
TXK tyrosine kinase
chr12_+_25973748 0.65 ENST00000542865.5
Ras association domain family member 8
chr1_+_171185293 0.65 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr2_-_151973991 0.65 ENST00000534999.6
ENST00000637217.1
ENST00000360283.11
calcium voltage-gated channel auxiliary subunit beta 4
chr5_+_151771943 0.65 ENST00000520177.6
ENST00000678854.1
ENST00000520006.2
ENST00000677105.1
ENST00000678101.1
ENST00000678910.1
ENST00000356245.8
ENST00000678646.1
ENST00000677433.1
ENST00000677369.1
ENST00000677284.1
ENST00000678564.1
G3BP stress granule assembly factor 1
chr9_-_114657791 0.64 ENST00000423632.3
testis expressed 53
chr19_+_3224649 0.64 ENST00000292672.7
CUGBP Elav-like family member 5
chr6_-_138218491 0.64 ENST00000527246.3
prostate and breast cancer overexpressed 1
chr4_+_70397931 0.64 ENST00000399575.7
opiorphin prepropeptide
chr14_+_21997531 0.63 ENST00000390445.2
T cell receptor alpha variable 17
chr19_+_3224701 0.63 ENST00000541430.6
CUGBP Elav-like family member 5
chr8_+_76681208 0.63 ENST00000651372.2
zinc finger homeobox 4
chr11_+_62856072 0.62 ENST00000377890.6
ENST00000681467.1
ENST00000538084.2
ENST00000681569.1
ENST00000377891.6
ENST00000680725.1
ENST00000377889.6
solute carrier family 3 member 2
chr7_-_18027839 0.62 ENST00000506618.5
phosphoribosyl pyrophosphate synthetase 1 like 1
chrX_+_1268786 0.62 ENST00000501036.7
ENST00000417535.7
colony stimulating factor 2 receptor subunit alpha
chr14_-_74426102 0.62 ENST00000554953.1
ENST00000331628.8
synapse differentiation inducing 1 like
chr17_-_66229380 0.61 ENST00000205948.11
apolipoprotein H
chr3_+_98147479 0.61 ENST00000641380.1
olfactory receptor family 5 subfamily H member 14
chr2_+_88885397 0.60 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr12_+_6724071 0.60 ENST00000229251.7
ENST00000539735.5
ENST00000538410.5
COP9 signalosome subunit 7A
chr9_-_2844058 0.60 ENST00000397885.3
pumilio RNA binding family member 3
chr11_+_89924064 0.60 ENST00000623787.3
tripartite motif containing 49D2
chr6_-_29087313 0.60 ENST00000377173.4
olfactory receptor family 2 subfamily B member 3
chr17_+_42980547 0.59 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr3_-_15341368 0.58 ENST00000408919.7
SH3 domain binding protein 5
chrX_+_15749848 0.58 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr13_+_114314474 0.58 ENST00000463003.2
ENST00000645174.1
ENST00000361283.4
ENST00000644294.1
chromosome alignment maintaining phosphoprotein 1
chr6_-_35512863 0.58 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TUB like protein 1
chr1_+_162069768 0.58 ENST00000530878.5
nitric oxide synthase 1 adaptor protein
chr5_-_16742221 0.57 ENST00000505695.5
myosin X
chr15_-_58014097 0.56 ENST00000559517.5
aldehyde dehydrogenase 1 family member A2
chr18_+_616672 0.56 ENST00000338387.11
clusterin like 1
chr1_+_13583762 0.55 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr2_-_151971750 0.55 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr18_+_63542365 0.54 ENST00000269491.6
ENST00000382768.2
serpin family B member 12
chr1_+_44405164 0.52 ENST00000355387.6
ring finger protein 220
chr14_+_21990357 0.52 ENST00000390444.1
T cell receptor alpha variable 16
chr6_-_32192630 0.51 ENST00000375040.8
G protein signaling modulator 3
chr12_-_76423256 0.51 ENST00000546946.5
oxysterol binding protein like 8
chr6_+_30067530 0.51 ENST00000376765.6
ENST00000376763.5
protein phosphatase 1 regulatory inhibitor subunit 11
chr9_-_21368962 0.50 ENST00000610660.1
interferon alpha 13
chr14_+_73591873 0.50 ENST00000326303.5
acyl-CoA thioesterase 4
chr1_+_149475933 0.50 ENST00000612881.4
NBPF member 19
chr21_-_30813270 0.50 ENST00000329621.6
keratin associated protein 8-1
chr1_+_149499966 0.50 ENST00000426482.3
NBPF member 19
chr5_-_136365476 0.50 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
transient receptor potential cation channel subfamily C member 7
chr16_-_69754913 0.49 ENST00000268802.10
NIN1 (RPN12) binding protein 1 homolog
chr14_+_67189393 0.49 ENST00000524532.5
ENST00000612183.4
ENST00000530728.5
family with sequence similarity 71 member D
chrX_-_64395417 0.49 ENST00000374852.4
myotubularin related protein 8
chr3_+_35679614 0.48 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr18_+_63907948 0.48 ENST00000238508.8
serpin family B member 10
chr1_+_237042176 0.48 ENST00000366574.7
ryanodine receptor 2
chr11_+_59142811 0.48 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr18_-_5396265 0.48 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr8_+_41529212 0.48 ENST00000520710.5
ENST00000518671.5
GINS complex subunit 4
chr7_+_120273129 0.48 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr8_-_81686274 0.48 ENST00000449740.6
ENST00000311489.8
ENST00000521360.5
ENST00000519964.5
ENST00000256108.10
ENST00000518202.5
inositol monophosphatase 1
chr6_-_169253835 0.48 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr12_+_75334655 0.48 ENST00000378695.9
GLIPR1 like 1
chr19_+_14028148 0.48 ENST00000431365.3
ENST00000585987.1
relaxin 3
chr3_+_130931893 0.48 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr9_-_65285209 0.47 ENST00000377420.1
forkhead box D4 like 5
chr7_-_141702151 0.47 ENST00000536163.6
DENN domain containing 11
chr1_-_146144804 0.47 ENST00000583866.9
ENST00000617010.2
NBPF member 10
chr19_-_42427379 0.46 ENST00000244289.9
lipase E, hormone sensitive type
chr4_-_69653223 0.46 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase family 2 member A1 complex locus
chr1_+_149477960 0.46 ENST00000369227.7
NBPF member 19
chr7_-_23470469 0.46 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr12_-_9999176 0.45 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr3_+_63443076 0.45 ENST00000295894.9
synaptoporin
chr6_-_49636832 0.45 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chr9_+_107306459 0.45 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr21_-_43076362 0.45 ENST00000359624.7
ENST00000352178.9
cystathionine beta-synthase
chr11_-_116787979 0.44 ENST00000429220.5
ENST00000444935.5
ENST00000227322.8
ZPR1 zinc finger
chr1_+_162069674 0.44 ENST00000361897.10
nitric oxide synthase 1 adaptor protein
chr4_+_76074701 0.44 ENST00000355810.9
ENST00000349321.7
ADP-ribosyltransferase 3 (inactive)
chr1_-_31919093 0.43 ENST00000602683.5
ENST00000470404.5
protein tyrosine phosphatase 4A2
chr13_-_46105009 0.43 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr5_-_79069668 0.42 ENST00000255189.8
dimethylglycine dehydrogenase
chr2_-_213151590 0.42 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr11_+_31812307 0.42 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAX6 upstream antisense RNA
novel protein
chr1_-_31919368 0.42 ENST00000457805.6
ENST00000602725.5
ENST00000679970.1
protein tyrosine phosphatase 4A2
novel protein
chr10_+_49637400 0.42 ENST00000640822.1
choline O-acetyltransferase
chr11_-_102874974 0.42 ENST00000571244.3
matrix metallopeptidase 12
chr3_-_112845950 0.41 ENST00000398214.5
CD200 receptor 1 like
chr3_-_186544377 0.41 ENST00000307944.6
crystallin gamma S
chr1_+_67166448 0.41 ENST00000347310.10
interleukin 23 receptor
chr14_+_22086401 0.41 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr3_+_123067016 0.40 ENST00000316218.12
protein disulfide isomerase family A member 5
chr8_+_81280527 0.40 ENST00000297258.11
fatty acid binding protein 5
chr17_-_4263847 0.40 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr6_-_32192845 0.40 ENST00000487761.5
G protein signaling modulator 3
chr6_+_10887036 0.40 ENST00000283141.11
synaptonemal complex protein 2 like
chr9_-_41128681 0.40 ENST00000622588.2
forkhead box D4 like 6
chr3_-_57199938 0.40 ENST00000473921.2
ENST00000295934.8
HESX homeobox 1
chr11_-_14971179 0.40 ENST00000486207.5
calcitonin related polypeptide alpha
chr3_-_48089203 0.40 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chr18_+_31591869 0.39 ENST00000237014.8
transthyretin
chr16_-_2264221 0.39 ENST00000566397.5
RNA binding protein with serine rich domain 1
chr11_-_76206407 0.39 ENST00000621122.1
ENST00000322563.8
Wnt family member 11
chr5_+_66144204 0.39 ENST00000612404.4
splicing regulatory glutamic acid and lysine rich protein 1
chr19_-_32971909 0.39 ENST00000305768.10
ENST00000590597.6
ENST00000591863.1
centrosomal protein 89

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.7 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.8 3.2 GO:0050925 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.6 1.8 GO:1903487 regulation of lactation(GO:1903487)
0.6 1.8 GO:0009720 detection of hormone stimulus(GO:0009720)
0.5 5.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.5 9.0 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.4 1.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.3 1.0 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.3 0.9 GO:0002339 B cell selection(GO:0002339)
0.3 1.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 0.8 GO:0006147 guanine catabolic process(GO:0006147)
0.2 1.5 GO:0060356 leucine import(GO:0060356)
0.2 1.0 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.2 1.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 1.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.7 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.2 1.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 1.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.8 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.2 1.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 0.8 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 0.6 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 1.1 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.8 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) homocysteine catabolic process(GO:0043418) L-cysteine metabolic process(GO:0046439)
0.1 0.4 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.4 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.5 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.9 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.4 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.6 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.4 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.9 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 2.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 2.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.7 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 0.7 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 1.5 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.5 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 1.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 2.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.5 GO:0042758 long-chain fatty acid catabolic process(GO:0042758) diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 1.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 2.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.6 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0019376 galactolipid catabolic process(GO:0019376)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:2001302 regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.6 GO:0035799 ureter maturation(GO:0035799)
0.0 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.0 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 1.1 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.0 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 3.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 1.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0007614 short-term memory(GO:0007614)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.9 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 2.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.7 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:1901253 mesodermal cell fate determination(GO:0007500) regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0070723 response to cholesterol(GO:0070723)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0001808 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.6 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.4 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 2.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.9 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 1.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.0 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 1.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 2.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 2.4 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 3.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 7.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 4.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 1.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 0.9 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.3 1.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.3 0.8 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 1.2 GO:0035473 lipase binding(GO:0035473)
0.2 1.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 0.8 GO:0016662 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2 0.8 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.2 1.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 1.3 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.7 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.8 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 2.8 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 3.2 GO:0030275 LRR domain binding(GO:0030275)
0.1 1.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 2.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.9 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 1.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 2.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 1.2 GO:0051400 BH domain binding(GO:0051400)
0.1 0.9 GO:0015250 water channel activity(GO:0015250)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 1.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 3.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0050733 DNA topoisomerase binding(GO:0044547) RS domain binding(GO:0050733)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 9.0 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 3.3 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.4 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 4.0 PID FOXO PATHWAY FoxO family signaling
0.0 2.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 3.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 12.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 2.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 2.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)