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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for DBP

Z-value: 1.26

Motif logo

Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
ENSG00000105516.11 DBP

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DBPhg38_v1_chr19_-_48634526_486346360.629.2e-04Click!

Activity profile of DBP motif

Sorted Z-values of DBP motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DBP

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_61081728 8.44 ENST00000371189.8
nuclear factor I A
chr3_-_52445085 6.33 ENST00000475739.1
ENST00000231721.7
semaphorin 3G
chr4_-_185810894 5.47 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr1_+_61082398 5.33 ENST00000664149.1
nuclear factor I A
chr9_+_2158239 4.35 ENST00000635133.1
ENST00000634931.1
ENST00000423555.6
ENST00000382185.6
ENST00000302401.8
ENST00000382183.6
ENST00000417599.6
ENST00000382186.6
ENST00000635530.1
ENST00000635388.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_57631735 4.33 ENST00000377918.8
protocadherin 17
chr1_+_61082553 4.15 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr1_+_81800368 4.01 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr4_-_16898561 3.98 ENST00000515064.5
ENST00000441778.6
LIM domain binding 2
chr4_-_16898619 3.95 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LIM domain binding 2
chr14_+_61321571 3.86 ENST00000332981.11
protein kinase C eta
chr1_+_113979391 3.86 ENST00000393300.6
ENST00000369551.5
olfactomedin like 3
chr1_+_113979460 3.85 ENST00000320334.5
olfactomedin like 3
chr9_+_2158487 3.80 ENST00000634706.1
ENST00000634338.1
ENST00000635688.1
ENST00000634435.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_58577244 3.76 ENST00000371225.4
tumor associated calcium signal transducer 2
chr1_+_84144260 3.63 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr18_+_75210755 3.58 ENST00000322038.5
teashirt zinc finger homeobox 1
chr13_+_31945826 3.48 ENST00000647500.1
FRY microtubule binding protein
chr18_+_75210789 3.41 ENST00000580243.3
teashirt zinc finger homeobox 1
chr3_+_40100007 3.16 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr3_+_141386862 3.14 ENST00000513258.5
zinc finger and BTB domain containing 38
chr10_-_62816341 3.13 ENST00000242480.4
ENST00000637191.1
early growth response 2
chr10_+_35195124 2.95 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr18_-_25352116 2.93 ENST00000584787.5
ENST00000538137.6
ENST00000361524.8
zinc finger protein 521
chr5_-_111756245 2.80 ENST00000447165.6
neuronal regeneration related protein
chr14_-_91946989 2.73 ENST00000556154.5
fibulin 5
chr13_+_32031706 2.54 ENST00000542859.6
FRY microtubule binding protein
chrX_-_10833643 2.24 ENST00000380785.5
ENST00000380787.5
midline 1
chr10_-_124093582 2.24 ENST00000462406.1
ENST00000435907.6
carbohydrate sulfotransferase 15
chr3_-_185821092 2.04 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr7_-_122144231 2.03 ENST00000679511.1
ENST00000417368.7
ENST00000473553.5
aminoadipate-semialdehyde synthase
chr8_-_17676484 2.01 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr10_-_62816309 1.92 ENST00000411732.3
early growth response 2
chr5_-_88731827 1.90 ENST00000627170.2
myocyte enhancer factor 2C
chr9_+_79572572 1.90 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr20_-_23086316 1.87 ENST00000246006.5
CD93 molecule
chr9_+_79572715 1.87 ENST00000265284.10
TLE family member 4, transcriptional corepressor
chrX_-_126552801 1.85 ENST00000371126.3
DDB1 and CUL4 associated factor 12 like 1
chr21_-_38661694 1.84 ENST00000417133.6
ENST00000398910.5
ENST00000442448.5
ENST00000429727.6
ETS transcription factor ERG
chr3_-_71305986 1.79 ENST00000647614.1
forkhead box P1
chr9_-_95509241 1.77 ENST00000331920.11
patched 1
chrX_+_150363306 1.72 ENST00000370401.7
ENST00000432680.7
mastermind like domain containing 1
chr21_-_26843063 1.70 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chrX_+_150363258 1.69 ENST00000683696.1
mastermind like domain containing 1
chr13_-_99016034 1.66 ENST00000448493.7
dedicator of cytokinesis 9
chr21_-_26843012 1.63 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_-_158173004 1.60 ENST00000585682.6
golgi associated kinase 1B
chr14_+_24120956 1.54 ENST00000558325.2
novel protein
chr18_-_55587335 1.54 ENST00000638154.3
transcription factor 4
chr9_-_81689536 1.52 ENST00000376499.8
TLE family member 1, transcriptional corepressor
chr20_+_11917859 1.52 ENST00000618296.4
ENST00000378226.7
BTB domain containing 3
chr17_+_69502397 1.49 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr12_-_57818704 1.49 ENST00000549994.1
advillin
chr5_-_88877967 1.45 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr16_+_30949054 1.43 ENST00000318663.5
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr4_-_137532452 1.41 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chrX_+_28587411 1.40 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chrX_-_24027186 1.36 ENST00000328046.8
kelch like family member 15
chr5_+_73813518 1.34 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chr3_+_124094663 1.27 ENST00000460856.5
ENST00000240874.7
kalirin RhoGEF kinase
chr9_-_13165442 1.26 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr5_+_62578810 1.25 ENST00000334994.6
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr11_-_66677748 1.24 ENST00000525754.5
ENST00000531969.5
ENST00000524637.1
ENST00000531036.2
ENST00000310046.9
RNA binding motif protein 4B
chr7_-_129952631 1.21 ENST00000473814.6
ENST00000490974.1
ubiquitin conjugating enzyme E2 H
chr8_-_29263063 1.20 ENST00000524189.6
kinesin family member 13B
chr17_+_60677822 1.19 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr22_+_37805218 1.18 ENST00000340857.4
H1.0 linker histone
chr17_+_2337480 1.17 ENST00000268989.8
ENST00000426855.6
small G protein signaling modulator 2
chr11_+_121590388 1.16 ENST00000527934.1
sortilin related receptor 1
chr9_-_122213903 1.15 ENST00000464484.3
LIM homeobox 6
chr9_-_20382461 1.14 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr3_-_149657996 1.13 ENST00000360632.8
ENST00000467467.5
ENST00000460517.1
WW domain containing transcription regulator 1
chr3_+_141324208 1.12 ENST00000509842.5
zinc finger and BTB domain containing 38
chr9_-_122213874 1.11 ENST00000482062.1
LIM homeobox 6
chr1_+_92168915 1.11 ENST00000637221.2
BTB domain containing 8
chr6_+_143608170 1.08 ENST00000427704.6
ENST00000305766.10
phosphatase and actin regulator 2
chr1_-_85404494 1.07 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr2_-_215393126 1.03 ENST00000456923.5
fibronectin 1
chr19_+_4909430 1.02 ENST00000620565.4
ENST00000613817.4
ENST00000624301.3
ENST00000650932.1
ubiquitin like with PHD and ring finger domains 1
chr1_+_28438104 1.01 ENST00000633167.1
ENST00000373836.4
phosphatase and actin regulator 4
chr4_+_107989880 1.00 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
hydroxyacyl-CoA dehydrogenase
chr11_-_19240936 0.98 ENST00000250024.9
E2F transcription factor 8
chr8_-_6563044 0.97 ENST00000338312.10
angiopoietin 2
chr17_-_48590231 0.96 ENST00000476342.1
ENST00000460160.5
ENST00000498678.6
ENST00000472863.5
homeobox B3
chr8_+_67952028 0.95 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr11_+_31650024 0.93 ENST00000638317.1
elongator acetyltransferase complex subunit 4
chr9_+_79571956 0.90 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr17_+_75110021 0.89 ENST00000584947.1
armadillo repeat containing 7
chr3_+_141387616 0.89 ENST00000509883.5
zinc finger and BTB domain containing 38
chr8_+_42338477 0.86 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr2_+_134254065 0.85 ENST00000281923.4
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr1_+_87331668 0.83 ENST00000370542.1
LIM domain only 4
chr3_+_124094696 0.83 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
kalirin RhoGEF kinase
chr3_+_182793478 0.82 ENST00000493826.1
ENST00000323116.10
ATPase phospholipid transporting 11B (putative)
chr11_+_123590939 0.80 ENST00000646146.1
GRAM domain containing 1B
chr1_+_153728042 0.79 ENST00000318967.7
ENST00000435409.6
integrator complex subunit 3
chr17_-_48545077 0.79 ENST00000330070.6
homeobox B2
chr3_-_114624193 0.78 ENST00000481632.5
zinc finger and BTB domain containing 20
chr8_-_6563238 0.76 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr11_+_103109522 0.76 ENST00000334267.11
dynein cytoplasmic 2 heavy chain 1
chr3_-_114624979 0.74 ENST00000676079.1
zinc finger and BTB domain containing 20
chr2_-_73293538 0.74 ENST00000436467.4
ENST00000545030.1
early growth response 4
chr3_-_114624921 0.73 ENST00000393785.6
zinc finger and BTB domain containing 20
chr2_+_209653171 0.72 ENST00000447185.5
microtubule associated protein 2
chr8_-_6563409 0.72 ENST00000325203.9
angiopoietin 2
chr14_+_58298497 0.72 ENST00000348476.7
ENST00000355431.8
ENST00000395168.7
AT-rich interaction domain 4A
chr15_+_58410543 0.70 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chrX_-_126166273 0.70 ENST00000360028.4
DDB1 and CUL4 associated factor 12 like 2
chr2_-_191847068 0.69 ENST00000304141.5
caveolae associated protein 2
chr10_-_63269057 0.68 ENST00000542921.5
jumonji domain containing 1C
chr5_+_102808057 0.67 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr1_+_155078829 0.67 ENST00000368408.4
ephrin A3
chr8_-_101790934 0.67 ENST00000523645.5
ENST00000520346.1
ENST00000220931.11
ENST00000522448.5
ENST00000522951.5
ENST00000522252.5
ENST00000519098.5
neurocalcin delta
chr6_-_31897675 0.66 ENST00000375530.8
ENST00000375537.8
euchromatic histone lysine methyltransferase 2
chr8_+_42338454 0.66 ENST00000532157.5
ENST00000520008.5
DNA polymerase beta
chr5_-_141673160 0.64 ENST00000513878.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr17_-_48101087 0.63 ENST00000393408.7
chromobox 1
chrX_+_130339886 0.63 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
solute carrier family 25 member 14
chr5_+_141208697 0.63 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
protocadherin beta 12
chrX_+_130339941 0.62 ENST00000218197.9
solute carrier family 25 member 14
chr14_-_36582593 0.62 ENST00000258829.6
NK2 homeobox 8
chr12_-_89352395 0.60 ENST00000308385.6
dual specificity phosphatase 6
chr3_+_152299570 0.59 ENST00000485910.5
ENST00000463374.5
muscleblind like splicing regulator 1
chr17_+_30378903 0.59 ENST00000225719.9
carboxypeptidase D
chr8_+_133113483 0.58 ENST00000521107.1
thyroglobulin
chr8_-_53842899 0.58 ENST00000524234.1
ENST00000521275.5
ENST00000396774.6
ATPase H+ transporting V1 subunit H
chr2_-_163735989 0.57 ENST00000333129.4
ENST00000409634.5
fidgetin, microtubule severing factor
chr4_+_87608529 0.57 ENST00000651931.1
dentin sialophosphoprotein
chr17_+_4710622 0.56 ENST00000574954.5
ENST00000269260.7
ENST00000346341.6
ENST00000572457.5
ENST00000381488.10
ENST00000412477.7
ENST00000571428.5
ENST00000575877.5
arrestin beta 2
chr6_+_26251607 0.56 ENST00000619466.2
H2B clustered histone 9
chr20_+_45306834 0.56 ENST00000343694.8
ENST00000372741.7
ENST00000372743.5
recombination signal binding protein for immunoglobulin kappa J region like
chr10_-_125160499 0.54 ENST00000494626.6
ENST00000337195.9
C-terminal binding protein 2
chr17_+_28042839 0.53 ENST00000582037.2
nemo like kinase
chr18_-_24311495 0.52 ENST00000357041.8
oxysterol binding protein like 1A
chrX_+_135520616 0.50 ENST00000370752.4
ENST00000639893.2
integrator complex subunit 6 like
chr17_+_28042660 0.49 ENST00000407008.8
nemo like kinase
chr10_-_17129786 0.48 ENST00000377833.10
cubilin
chr9_+_132978651 0.48 ENST00000636137.1
growth factor independent 1B transcriptional repressor
chr19_-_39391029 0.48 ENST00000221265.8
PAF1 homolog, Paf1/RNA polymerase II complex component
chr1_-_248277976 0.47 ENST00000641220.1
olfactory receptor family 2 subfamily T member 33
chr4_+_105552611 0.47 ENST00000265154.6
ENST00000420470.3
Rho guanine nucleotide exchange factor 38
chrX_-_19799751 0.47 ENST00000379698.8
SH3 domain containing kinase binding protein 1
chr3_+_100492548 0.47 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr2_-_210171402 0.46 ENST00000281772.14
KAT8 regulatory NSL complex subunit 1 like
chr16_-_75248190 0.46 ENST00000542031.6
BCAR1 scaffold protein, Cas family member
chr2_+_209580024 0.46 ENST00000392194.5
microtubule associated protein 2
chr17_-_35868885 0.45 ENST00000604834.6
HEAT repeat containing 9
chr12_-_89352487 0.43 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr9_-_95516959 0.42 ENST00000437951.6
ENST00000430669.6
ENST00000468211.6
patched 1
chr3_-_33659097 0.42 ENST00000461133.8
ENST00000496954.2
cytoplasmic linker associated protein 2
chr17_-_35868858 0.39 ENST00000603870.5
ENST00000603218.1
HEAT repeat containing 9
chr9_+_128275343 0.39 ENST00000495313.5
ENST00000372898.6
SWI5 homologous recombination repair protein
chr3_+_152299392 0.38 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
muscleblind like splicing regulator 1
chr22_-_31346317 0.38 ENST00000266269.10
POZ/BTB and AT hook containing zinc finger 1
chr7_-_151248668 0.37 ENST00000262188.13
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_+_209579598 0.37 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr12_+_32106885 0.37 ENST00000550207.1
BICD cargo adaptor 1
chr11_-_62646598 0.36 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
glucosidase II alpha subunit
chr2_-_110534010 0.36 ENST00000437167.1
RANBP2 like and GRIP domain containing 6
chr9_-_108855978 0.35 ENST00000374667.5
actin like 7B
chr12_+_32106762 0.35 ENST00000551848.1
ENST00000652176.1
BICD cargo adaptor 1
chr9_+_132978687 0.34 ENST00000372122.4
ENST00000372123.5
growth factor independent 1B transcriptional repressor
chr17_+_50746534 0.34 ENST00000511974.5
LUC7 like 3 pre-mRNA splicing factor
chr11_-_123061173 0.33 ENST00000526110.5
ENST00000227378.7
heat shock protein family A (Hsp70) member 8
chrX_+_41339931 0.33 ENST00000642424.1
DEAD-box helicase 3 X-linked
chr19_-_42069496 0.32 ENST00000593562.5
glutamate ionotropic receptor kainate type subunit 5
chr5_+_138338256 0.32 ENST00000513056.5
ENST00000239906.10
ENST00000511276.1
family with sequence similarity 53 member C
chr10_-_100987433 0.32 ENST00000448244.5
ENST00000370241.7
ENST00000370236.5
ENST00000370234.4
ENST00000299179.9
ENST00000318325.6
ENST00000370242.8
ENST00000342071.5
ENST00000318364.12
ENST00000477279.1
mitochondrial ribosomal protein L43
chrX_-_32412220 0.31 ENST00000619831.5
dystrophin
chrX_-_101386166 0.31 ENST00000308731.8
ENST00000372880.5
Bruton tyrosine kinase
chr5_-_135399863 0.30 ENST00000510038.1
ENST00000304332.8
macroH2A.1 histone
chr4_+_70721953 0.30 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr8_+_19939246 0.29 ENST00000650287.1
lipoprotein lipase
chr11_-_31810991 0.29 ENST00000640684.1
paired box 6
chr19_-_39391137 0.29 ENST00000595564.5
PAF1 homolog, Paf1/RNA polymerase II complex component
chr17_+_2337622 0.29 ENST00000574563.5
small G protein signaling modulator 2
chr5_+_32710630 0.29 ENST00000326958.5
natriuretic peptide receptor 3
chr7_-_117323041 0.29 ENST00000491214.1
ENST00000265441.8
Wnt family member 2
chr4_+_113292838 0.28 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr14_+_75985747 0.28 ENST00000679083.1
ENST00000314067.11
ENST00000238628.10
ENST00000556742.1
intraflagellar transport 43
chr9_-_98708856 0.28 ENST00000259455.4
gamma-aminobutyric acid type B receptor subunit 2
chrX_+_100584928 0.28 ENST00000373031.5
tenomodulin
chr17_+_44352109 0.27 ENST00000586242.1
granulin precursor
chr1_+_211259932 0.26 ENST00000367005.8
REST corepressor 3
chr8_+_26390362 0.26 ENST00000518611.5
BCL2 interacting protein 3 like
chr6_+_44227025 0.26 ENST00000371708.1
solute carrier family 29 member 1 (Augustine blood group)
chr19_+_10655023 0.26 ENST00000590009.5
interleukin enhancer binding factor 3
chr5_+_177133741 0.25 ENST00000439151.7
nuclear receptor binding SET domain protein 1
chr9_+_128276222 0.25 ENST00000608796.6
ENST00000419867.7
ENST00000418976.2
SWI5 homologous recombination repair protein
chr5_+_181040260 0.25 ENST00000515271.1
ENST00000327705.14
butyrophilin like 9
chr13_-_41019289 0.25 ENST00000239882.7
E74 like ETS transcription factor 1
chr17_+_50746614 0.24 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr15_+_48191648 0.24 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
solute carrier family 12 member 1
cortexin 2
chr7_+_100015588 0.24 ENST00000324306.11
ENST00000426572.5
zinc finger with KRAB and SCAN domains 1
chr6_+_21593742 0.24 ENST00000244745.4
SRY-box transcription factor 4
chr10_-_77637633 0.23 ENST00000638223.1
ENST00000639544.1
ENST00000640807.1
ENST00000434208.6
ENST00000626620.3
ENST00000638575.1
ENST00000638759.1
potassium calcium-activated channel subfamily M alpha 1
chr4_+_113292925 0.23 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr10_+_84452208 0.23 ENST00000480006.1
coiled-coil serine rich protein 2
chr1_+_56854764 0.23 ENST00000361249.4
complement C8 alpha chain
chr19_+_39391323 0.23 ENST00000615911.4
ENST00000315588.11
ENST00000594368.5
ENST00000596297.1
mediator complex subunit 29

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
1.5 6.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.3 3.8 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.2 7.0 GO:0060023 soft palate development(GO:0060023)
0.8 2.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.8 0.8 GO:0021569 rhombomere 3 development(GO:0021569)
0.7 2.0 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.6 17.9 GO:0072189 ureter development(GO:0072189)
0.5 2.2 GO:0010157 response to chlorate(GO:0010157)
0.5 3.6 GO:0097338 response to clozapine(GO:0097338)
0.5 1.0 GO:0061386 closure of optic fissure(GO:0061386)
0.5 1.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 3.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 1.2 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 1.5 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.4 3.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3 1.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.3 1.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.3 1.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.3 0.8 GO:0015917 aminophospholipid transport(GO:0015917)
0.3 1.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 1.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 1.0 GO:0021546 rhombomere development(GO:0021546)
0.2 3.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 7.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 2.1 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.2 1.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 3.6 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.2 1.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 0.7 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.2 2.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.7 GO:0018032 protein amidation(GO:0018032)
0.1 2.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 5.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.3 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.1 0.6 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.3 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 3.2 GO:0060347 heart trabecula formation(GO:0060347)
0.1 1.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 1.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) B cell selection(GO:0002339) B cell cytokine production(GO:0002368)
0.1 4.3 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.7 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) regulation of aspartic-type peptidase activity(GO:1905245)
0.1 2.7 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 6.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.8 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 0.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 1.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 3.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 1.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 2.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 2.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.7 GO:0034638 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0 0.6 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 7.9 GO:0007286 spermatid development(GO:0007286)
0.0 1.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.7 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.5 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0001080 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 1.1 GO:0051693 actin filament capping(GO:0051693)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 1.3 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 3.0 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.9 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0071953 elastic fiber(GO:0071953)
0.2 2.2 GO:0044294 dendritic growth cone(GO:0044294)
0.2 8.5 GO:0071564 npBAF complex(GO:0071564)
0.2 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.7 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.2 3.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.6 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 3.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 3.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 4.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 5.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 5.0 GO:0072562 blood microparticle(GO:0072562)
0.0 5.9 GO:0030018 Z disc(GO:0030018)
0.0 12.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.8 GO:0035577 azurophil granule membrane(GO:0035577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.6 3.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.6 7.9 GO:0030274 LIM domain binding(GO:0030274)
0.4 2.2 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.4 1.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 2.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.2 1.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 3.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 7.8 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.9 GO:0001849 complement component C1q binding(GO:0001849)
0.2 6.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.0 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 4.3 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.7 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 5.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.9 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 8.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 1.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.3 GO:0043273 CTPase activity(GO:0043273)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.9 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 2.0 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 4.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 3.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 18.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 2.6 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 13.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 9.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 5.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 2.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 4.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 6.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 3.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation