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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for DBX2_HLX

Z-value: 0.76

Motif logo

Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
ENSG00000185610.6 DBX2
ENSG00000136630.13 HLX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg38_v1_chr1_+_220879434_2208794570.783.8e-06Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_155666718 6.21 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_41613476 4.56 ENST00000508466.1
LIM and calponin homology domains 1
chr1_+_84164962 3.35 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr4_+_41538143 3.20 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr3_-_18438767 2.46 ENST00000454909.6
SATB homeobox 1
chr1_+_76074698 2.29 ENST00000328299.4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr3_-_65622073 2.07 ENST00000621418.4
ENST00000611645.4
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_+_14583076 2.03 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr9_+_72577939 1.97 ENST00000645773.1
transmembrane channel like 1
chr2_-_182242031 1.85 ENST00000358139.6
phosphodiesterase 1A
chr11_-_63608542 1.83 ENST00000540943.1
phospholipase A and acyltransferase 3
chr1_-_91906280 1.76 ENST00000370399.6
transforming growth factor beta receptor 3
chr14_-_53956811 1.73 ENST00000559087.5
ENST00000245451.9
bone morphogenetic protein 4
chr22_-_28712136 1.60 ENST00000464581.6
checkpoint kinase 2
chr22_-_28711931 1.59 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr12_-_9869345 1.55 ENST00000228438.3
C-type lectin domain family 2 member B
chr4_-_89836213 1.48 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr21_-_30497160 1.45 ENST00000334058.3
keratin associated protein 19-4
chr19_-_58353482 1.43 ENST00000263100.8
alpha-1-B glycoprotein
chr20_-_35147285 1.43 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr17_+_69502397 1.41 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chrX_-_77634229 1.35 ENST00000675732.1
ATRX chromatin remodeler
chr8_-_92103217 1.31 ENST00000615601.4
ENST00000523629.5
RUNX1 partner transcriptional co-repressor 1
chr4_-_139280179 1.29 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr9_+_72577369 1.28 ENST00000651183.1
transmembrane channel like 1
chr17_-_445939 1.26 ENST00000329099.4
refilin B
chr1_-_160954801 1.22 ENST00000368029.4
intelectin 2
chr7_+_107583919 1.21 ENST00000491150.5
B cell receptor associated protein 29
chr19_+_49513353 1.19 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr7_+_130486324 1.15 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chrX_+_77910656 1.12 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr18_-_55423757 1.11 ENST00000675707.1
transcription factor 4
chr3_-_142000353 1.11 ENST00000499676.5
transcription factor Dp-2
chr2_-_55269038 1.10 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
mitochondrial translational initiation factor 2
chr7_+_130486171 1.08 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr10_-_114684457 1.08 ENST00000392955.7
actin binding LIM protein 1
chr6_-_75363003 1.08 ENST00000370020.1
filamin A interacting protein 1
chr9_+_2015186 1.05 ENST00000357248.8
ENST00000450198.6
ENST00000634287.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_-_53510445 1.03 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr9_-_110337808 1.02 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr6_-_52994248 1.00 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr3_-_142029108 0.99 ENST00000497579.5
transcription factor Dp-2
chr8_-_3409528 0.98 ENST00000335551.11
CUB and Sushi multiple domains 1
chr9_-_5833014 0.98 ENST00000339450.10
endoplasmic reticulum metallopeptidase 1
chr10_+_35195843 0.98 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr10_-_114684612 0.97 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr4_-_137532452 0.96 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr19_-_4558417 0.95 ENST00000586965.1
semaphorin 6B
chr1_+_248013660 0.93 ENST00000355281.2
olfactory receptor family 2 subfamily L member 5
chr5_+_42548043 0.91 ENST00000618088.4
ENST00000612382.4
growth hormone receptor
chr9_+_2015335 0.90 ENST00000636559.1
ENST00000349721.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_109801978 0.90 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr13_-_109786567 0.88 ENST00000375856.5
insulin receptor substrate 2
chr15_-_19988117 0.88 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr9_+_72577788 0.87 ENST00000645208.2
transmembrane channel like 1
chr12_-_12350222 0.86 ENST00000543314.1
ENST00000396349.3
ENST00000535902.6
MANSC domain containing 1
chr1_+_81306096 0.85 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr18_+_6834473 0.83 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chr5_-_126595237 0.82 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr4_-_158159657 0.80 ENST00000590648.5
golgi associated kinase 1B
chr5_+_95731300 0.80 ENST00000379982.8
Rho related BTB domain containing 3
chr19_+_34926892 0.79 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr6_-_73452124 0.78 ENST00000680833.1
cyclic GMP-AMP synthase
chr13_-_52011337 0.77 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr12_+_20810698 0.76 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr15_+_75347030 0.74 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr8_-_85341659 0.74 ENST00000522389.5
carbonic anhydrase 1
chr6_-_110179995 0.73 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr12_-_10826358 0.73 ENST00000240619.2
taste 2 receptor member 10
chrX_+_55717733 0.72 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr9_+_96928310 0.72 ENST00000354649.7
NUT family member 2G
chrX_+_55717796 0.72 ENST00000262850.7
Ras related GTP binding B
chr10_+_5048748 0.71 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr6_-_52995170 0.71 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr4_-_162163955 0.71 ENST00000379164.8
follistatin like 5
chr14_+_56579782 0.70 ENST00000261556.11
ENST00000538838.5
transmembrane protein 260
chr22_+_41092869 0.70 ENST00000674155.1
E1A binding protein p300
chr15_+_66293541 0.69 ENST00000319212.9
ENST00000525109.1
DIS3 like exosome 3'-5' exoribonuclease
chr7_+_100119607 0.65 ENST00000262932.5
canopy FGF signaling regulator 4
chr5_-_112419251 0.65 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr2_-_58241259 0.64 ENST00000481670.2
ENST00000403676.5
ENST00000427708.6
ENST00000403295.7
ENST00000233741.9
ENST00000446381.5
ENST00000417361.1
ENST00000402135.7
ENST00000449070.5
FA complementation group L
chr2_-_178478499 0.64 ENST00000434643.6
FKBP prolyl isomerase 7
chr17_+_37491464 0.64 ENST00000613659.1
dual specificity phosphatase 14
chr14_-_89619118 0.63 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr16_+_81645352 0.62 ENST00000398040.8
c-Maf inducing protein
chr6_+_85449584 0.62 ENST00000369651.7
5'-nucleotidase ecto
chr9_-_92404559 0.61 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr1_+_178725147 0.60 ENST00000367634.6
Ral GEF with PH domain and SH3 binding motif 2
chrX_+_136205982 0.60 ENST00000628568.1
four and a half LIM domains 1
chrX_+_10158448 0.60 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr18_-_55635948 0.59 ENST00000565124.4
ENST00000398339.5
transcription factor 4
chr9_+_34652167 0.59 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr2_+_108588286 0.58 ENST00000332345.10
LIM zinc finger domain containing 1
chr3_+_107599309 0.57 ENST00000406780.5
BBX high mobility group box domain containing
chr17_-_40782544 0.56 ENST00000301656.4
keratin 27
chr16_+_24537693 0.56 ENST00000564314.5
ENST00000567686.5
RB binding protein 6, ubiquitin ligase
chr3_+_16174628 0.56 ENST00000339732.10
polypeptide N-acetylgalactosaminyltransferase 15
chr9_-_21228222 0.55 ENST00000413767.2
interferon alpha 17
chr5_-_88823763 0.55 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr1_+_212035717 0.55 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr1_+_196819731 0.54 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr19_-_51417700 0.54 ENST00000529627.1
ENST00000439889.6
sialic acid binding Ig like lectin 10
chr10_+_5094405 0.53 ENST00000380554.5
aldo-keto reductase family 1 member C3
chr19_+_49513154 0.53 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
Fc fragment of IgG receptor and transporter
chr6_+_26087281 0.52 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
homeostatic iron regulator
chr2_+_108588453 0.52 ENST00000393310.5
LIM zinc finger domain containing 1
chr13_+_77741160 0.52 ENST00000314070.9
ENST00000351546.7
SLAIN motif family member 1
chr1_-_53945567 0.52 ENST00000371378.6
heat shock protein family B (small) member 11
chr6_+_130018565 0.51 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr5_-_56116946 0.50 ENST00000434982.2
ankyrin repeat domain 55
chr1_-_53945584 0.50 ENST00000371377.3
heat shock protein family B (small) member 11
chr8_+_11809135 0.49 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr9_+_122371014 0.49 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr8_-_6978634 0.47 ENST00000382679.2
defensin alpha 1
chr20_-_25339731 0.47 ENST00000450393.5
ENST00000491682.5
abhydrolase domain containing 12, lysophospholipase
chr4_+_87608529 0.46 ENST00000651931.1
dentin sialophosphoprotein
chr4_-_151227881 0.46 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr3_+_158801926 0.45 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chr19_+_54451290 0.45 ENST00000610347.1
leukocyte receptor cluster member 8
chr16_-_66549839 0.45 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
thymidine kinase 2
chr20_-_31390483 0.45 ENST00000376315.2
defensin beta 119
chr15_+_24954912 0.44 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr2_+_102473219 0.43 ENST00000295269.5
solute carrier family 9 member A4
chr11_-_122116215 0.43 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr2_+_85584402 0.43 ENST00000306384.5
vesicle associated membrane protein 5
chr3_-_115071333 0.42 ENST00000462705.5
zinc finger and BTB domain containing 20
chr9_+_27109393 0.41 ENST00000406359.8
TEK receptor tyrosine kinase
chr9_+_2015275 0.41 ENST00000637103.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_-_2971048 0.41 ENST00000612421.3
serpin family B member 6
chr7_-_5959083 0.41 ENST00000539903.5
radial spoke head 10 homolog B
chr16_-_66550091 0.41 ENST00000564917.5
ENST00000677420.1
thymidine kinase 2
chr16_-_66550005 0.40 ENST00000527284.6
thymidine kinase 2
chr20_+_11890723 0.40 ENST00000254977.7
BTB domain containing 3
chr1_+_196943738 0.40 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
complement factor H related 2
chr9_+_73151833 0.40 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
annexin A1
chr6_+_158536398 0.40 ENST00000367090.4
transmembrane protein 181
chr12_+_59664677 0.40 ENST00000548610.5
solute carrier family 16 member 7
chr5_+_55160161 0.40 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr4_-_48780242 0.39 ENST00000507711.5
ENST00000358350.9
FRY like transcription coactivator
chr8_-_140764386 0.39 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr19_-_22422335 0.38 ENST00000357774.9
ENST00000601553.1
ENST00000593657.5
zinc finger protein 98
chr10_-_37857582 0.38 ENST00000395867.8
ENST00000611278.4
zinc finger protein 248
chr15_+_65550819 0.38 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr2_+_90038848 0.38 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr12_-_7503841 0.38 ENST00000359156.8
CD163 molecule
chr16_+_14708944 0.38 ENST00000526520.5
ENST00000531598.6
nuclear pore complex interacting protein family member A3
chr2_+_108607140 0.38 ENST00000410093.5
LIM zinc finger domain containing 1
chr6_+_28124596 0.38 ENST00000340487.5
zinc finger and SCAN domain containing 16
chr18_+_62539511 0.37 ENST00000586834.1
zinc finger CCHC-type containing 2
chr5_+_55853464 0.36 ENST00000652039.1
interleukin 31 receptor A
chr5_+_141199555 0.36 ENST00000624887.1
ENST00000354757.5
protocadherin beta 11
chr10_+_122560639 0.36 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr1_-_51331315 0.35 ENST00000262676.9
tetratricopeptide repeat domain 39A
chr16_-_28211476 0.35 ENST00000569951.1
ENST00000565698.5
exportin 6
chr6_+_146598979 0.35 ENST00000681847.1
androglobin
chr3_-_161105070 0.35 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_+_26103922 0.35 ENST00000377803.4
H4 clustered histone 3
chr1_+_152811971 0.34 ENST00000360090.4
late cornified envelope 1B
chr6_+_26087417 0.34 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator
chr10_+_122560679 0.33 ENST00000657942.1
deleted in malignant brain tumors 1
chr1_-_21050952 0.33 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr16_-_66550142 0.32 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
thymidine kinase 2
chr12_+_101594849 0.32 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr10_+_122560751 0.32 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr22_-_32464440 0.32 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr19_-_51417791 0.32 ENST00000353836.9
sialic acid binding Ig like lectin 10
chrX_-_18672101 0.32 ENST00000379984.4
retinoschisin 1
chr18_-_712618 0.32 ENST00000647584.2
ENST00000583771.1
ENST00000383578.7
enolase superfamily member 1
chr12_+_110846960 0.32 ENST00000545036.5
ENST00000308208.10
coiled-coil domain containing 63
chr2_+_108621260 0.32 ENST00000409441.5
LIM zinc finger domain containing 1
chr5_+_140848360 0.32 ENST00000532602.2
protocadherin alpha 9
chr11_-_2141238 0.32 ENST00000434045.6
insulin like growth factor 2
chr12_+_110847000 0.31 ENST00000552694.1
coiled-coil domain containing 63
chr5_+_140834230 0.31 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr17_+_32021005 0.31 ENST00000327564.11
ENST00000584368.5
ENST00000394713.7
ENST00000341671.11
leucine rich repeat containing 37B
chr22_+_44752552 0.31 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr11_+_4329865 0.30 ENST00000640302.1
SSU72 pseudogene 3
chr4_-_169612571 0.30 ENST00000507142.6
ENST00000510533.5
ENST00000439128.6
ENST00000511633.5
ENST00000512193.5
NIMA related kinase 1
chr3_-_185821092 0.30 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chrX_+_85003863 0.30 ENST00000373173.7
apolipoprotein O like
chr10_+_87357720 0.30 ENST00000412718.3
ENST00000381697.7
NUT family member 2D
chr17_+_56153458 0.29 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ankyrin repeat and fibronectin type III domain containing 1
chr5_+_175861628 0.29 ENST00000509837.5
complexin 2
chr17_+_3475959 0.29 ENST00000263080.3
aspartoacylase
chr3_-_161105224 0.29 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr2_+_90172802 0.28 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr12_+_20815672 0.28 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr8_+_2045037 0.28 ENST00000262113.9
myomesin 2
chr12_-_95116967 0.28 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr6_+_156776020 0.28 ENST00000346085.10
AT-rich interaction domain 1B
chr7_+_152025632 0.28 ENST00000430044.7
ENST00000431668.1
ENST00000446096.5
ENST00000423337.5
polypeptide N-acetylgalactosaminyltransferase 11
chr6_+_29111560 0.27 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr3_-_20012250 0.27 ENST00000389050.5
protein phosphatase 2C like domain containing 1
chr3_-_125520165 0.27 ENST00000251775.9
sorting nexin 4
chr7_+_117014881 0.27 ENST00000422922.5
ENST00000432298.5
suppression of tumorigenicity 7
chr2_+_186694007 0.27 ENST00000304698.10
family with sequence similarity 171 member B
chr4_+_70242583 0.27 ENST00000304954.3
casein kappa
chr8_+_2045058 0.27 ENST00000523438.1
myomesin 2
chr2_-_27489716 0.27 ENST00000260570.8
ENST00000675690.1
intraflagellar transport 172
chr5_+_102808057 0.27 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 1.9 GO:0060003 copper ion export(GO:0060003)
0.6 1.7 GO:0060503 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.6 1.7 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.5 3.3 GO:0097338 response to clozapine(GO:0097338)
0.5 1.4 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.5 1.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 1.3 GO:1904907 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.4 1.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.4 1.3 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.4 1.2 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.4 4.0 GO:0060005 vestibular reflex(GO:0060005)
0.4 1.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.3 1.8 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.3 0.9 GO:1904438 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.3 1.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.3 1.0 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2 1.5 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.8 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 1.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.5 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.9 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 2.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:0016116 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.6 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.6 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.1 0.3 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.1 0.4 GO:0009405 pathogenesis(GO:0009405)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.3 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 1.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.6 GO:0051552 flavone metabolic process(GO:0051552)
0.1 1.0 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.6 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 2.3 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.2 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.2 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.2 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.4 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.5 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 1.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 1.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.0 GO:2000192 negative regulation of fatty acid transport(GO:2000192)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 2.1 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.3 0.9 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 1.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 1.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 1.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 4.1 GO:0032426 stereocilium tip(GO:0032426)
0.2 3.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.3 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 2.4 GO:0071564 npBAF complex(GO:0071564)
0.1 0.2 GO:0030849 X chromosome(GO:0000805) autosome(GO:0030849)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 1.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 3.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.4 1.3 GO:0015616 DNA translocase activity(GO:0015616)
0.4 1.7 GO:0019770 IgG receptor activity(GO:0019770)
0.4 1.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.3 2.0 GO:0042806 fucose binding(GO:0042806)
0.3 1.0 GO:0035375 zymogen binding(GO:0035375)
0.3 1.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 4.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 1.8 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.3 1.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 1.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 2.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 0.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 3.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.6 GO:0039706 co-receptor binding(GO:0039706)
0.2 0.9 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 1.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.0 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.2 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 8.1 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.2 PID ATM PATHWAY ATM pathway
0.1 2.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 5.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 6.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.9 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 2.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism