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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for DLX5

Z-value: 0.27

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Transcription factors associated with DLX5

Gene Symbol Gene ID Gene Info
ENSG00000105880.7 DLX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX5hg38_v1_chr7_-_97024821_97024950-0.213.1e-01Click!

Activity profile of DLX5 motif

Sorted Z-values of DLX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_14674829 0.28 ENST00000443157.6
ENST00000253673.6
adhesion G protein-coupled receptor E3
chr19_-_14674886 0.27 ENST00000344373.8
ENST00000595472.1
adhesion G protein-coupled receptor E3
chr16_+_53099100 0.17 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr15_+_41621492 0.17 ENST00000570161.6
MAX dimerization protein MGA
chr15_+_41621134 0.16 ENST00000566718.6
MAX dimerization protein MGA
chr7_+_100119607 0.15 ENST00000262932.5
canopy FGF signaling regulator 4
chr12_+_6904962 0.15 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr1_+_100538131 0.14 ENST00000315033.5
G protein-coupled receptor 88
chr1_-_23344259 0.11 ENST00000476451.2
ENST00000302271.11
ENST00000606561.5
ENST00000374616.7
heterogeneous nuclear ribonucleoprotein R
chr17_+_75110021 0.11 ENST00000584947.1
armadillo repeat containing 7
chr1_-_23344314 0.11 ENST00000374612.5
ENST00000675048.1
ENST00000478691.5
heterogeneous nuclear ribonucleoprotein R
chr9_+_113463697 0.09 ENST00000317613.10
regulator of G protein signaling 3
chr6_+_27893411 0.09 ENST00000616182.2
H2B clustered histone 17
chr19_+_35748549 0.09 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr10_-_54801179 0.08 ENST00000373955.5
protocadherin related 15
chr6_+_106360668 0.08 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr11_-_33892010 0.08 ENST00000257818.3
LIM domain only 2
chr22_-_32464440 0.08 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr7_-_87220567 0.08 ENST00000433078.5
transmembrane protein 243
chr12_-_10826358 0.08 ENST00000240619.2
taste 2 receptor member 10
chr7_-_130441136 0.07 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr2_+_169584779 0.07 ENST00000678638.1
peptidylprolyl isomerase G
chr14_+_24070837 0.07 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr10_-_54801262 0.07 ENST00000373965.6
ENST00000616114.4
ENST00000621708.4
ENST00000495484.5
ENST00000395440.5
ENST00000395442.5
ENST00000617271.4
ENST00000395446.5
ENST00000409834.5
ENST00000361849.7
ENST00000373957.7
ENST00000395430.5
ENST00000395433.5
ENST00000437009.5
protocadherin related 15
chr13_+_35476740 0.07 ENST00000537702.5
neurobeachin
chr8_+_91249307 0.07 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr13_-_110242694 0.07 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
collagen type IV alpha 1 chain
chr3_+_186570663 0.06 ENST00000265028.8
DnaJ heat shock protein family (Hsp40) member B11
chr2_-_182522556 0.06 ENST00000435564.5
phosphodiesterase 1A
chr10_-_54801221 0.06 ENST00000644397.2
ENST00000395445.6
ENST00000613657.5
ENST00000320301.11
protocadherin related 15
chr12_-_24902243 0.06 ENST00000538118.5
branched chain amino acid transaminase 1
chr5_-_22853320 0.06 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr19_+_36115439 0.06 ENST00000629269.2
ENST00000221855.8
ENST00000651435.1
ENST00000589996.5
ENST00000591296.1
tubulin folding cofactor B
chr22_-_30564889 0.06 ENST00000401975.5
ENST00000428682.5
ENST00000423299.5
galactose-3-O-sulfotransferase 1
chr12_+_51424802 0.06 ENST00000453097.7
solute carrier family 4 member 8
chrX_-_16869840 0.06 ENST00000380084.8
RB binding protein 7, chromatin remodeling factor
chr5_-_160852200 0.05 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr10_+_96832906 0.05 ENST00000675537.1
ENST00000675117.1
ENST00000356016.7
ENST00000371097.8
ligand dependent nuclear receptor corepressor
chr3_+_158801926 0.05 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chr3_-_180679468 0.05 ENST00000651046.1
ENST00000476379.6
coiled-coil domain containing 39
chr7_-_30550761 0.05 ENST00000598361.4
ENST00000440438.6
novel protein
GARS1 divergent transcript
chr5_+_64505981 0.05 ENST00000334025.3
regulator of G protein signaling 7 binding protein
chr6_+_122717544 0.05 ENST00000354275.2
ENST00000368446.1
cAMP-dependent protein kinase inhibitor beta
chr4_-_7068033 0.05 ENST00000264954.5
GrpE like 1, mitochondrial
chr19_-_45782479 0.05 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr3_+_11137093 0.05 ENST00000438284.2
histamine receptor H1
chr8_-_7475082 0.05 ENST00000316169.2
defensin beta 104B
chr4_-_65670478 0.05 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPH receptor A5
chr19_-_36114850 0.05 ENST00000221859.9
RNA polymerase II subunit I
chr4_-_65670339 0.04 ENST00000273854.7
EPH receptor A5
chr11_-_72112068 0.04 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chrX_+_152831054 0.04 ENST00000370274.8
NAD(P) dependent steroid dehydrogenase-like
chr11_-_26722051 0.04 ENST00000396005.8
solute carrier family 5 member 12
chr1_-_77979054 0.04 ENST00000370768.7
ENST00000370767.5
ENST00000421641.1
far upstream element binding protein 1
chr10_+_114043858 0.04 ENST00000369295.4
adrenoceptor beta 1
chr4_-_142846275 0.04 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
inositol polyphosphate-4-phosphatase type II B
chr14_-_24242320 0.04 ENST00000557921.2
TERF1 interacting nuclear factor 2
chr10_+_96832252 0.04 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr19_+_4007714 0.04 ENST00000262971.3
protein inhibitor of activated STAT 4
chr10_-_49762276 0.04 ENST00000374103.9
oxoglutarate dehydrogenase L
chr2_+_30146993 0.04 ENST00000261353.9
ENST00000402003.7
yippee like 5
chr1_-_150697128 0.03 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr19_-_45782388 0.03 ENST00000458663.6
DM1 protein kinase
chr12_+_51424965 0.03 ENST00000514353.7
solute carrier family 4 member 8
chr19_+_49513353 0.03 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr16_+_590056 0.03 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C, member RAS oncogene family
chr9_+_34646589 0.03 ENST00000450095.6
galactose-1-phosphate uridylyltransferase
chr1_-_242449478 0.03 ENST00000427495.5
phospholipase D family member 5
chr2_+_30146941 0.03 ENST00000379520.7
ENST00000379519.7
yippee like 5
chr18_+_58221535 0.03 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr3_-_186570308 0.03 ENST00000446782.5
TBCC domain containing 1
chr14_-_67816574 0.03 ENST00000677026.1
ENST00000555452.1
ENST00000347230.9
ENST00000678386.1
ENST00000676620.1
ENST00000676512.1
zinc finger FYVE-type containing 26
chr9_+_34646654 0.03 ENST00000378842.8
galactose-1-phosphate uridylyltransferase
chr5_+_172641241 0.03 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr4_+_174918355 0.03 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM metallopeptidase domain 29
chr6_-_41733690 0.03 ENST00000419396.6
ENST00000678831.1
ENST00000394283.5
transcription factor EB
chrX_+_101390976 0.03 ENST00000392994.7
ribosomal protein L36a
chr10_-_49762335 0.03 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr10_+_97446194 0.03 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
zinc finger DHHC-type palmitoyltransferase 16
chr1_-_201171545 0.03 ENST00000367333.6
transmembrane protein 9
chr10_+_97446137 0.03 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
zinc finger DHHC-type palmitoyltransferase 16
chr1_+_160190567 0.02 ENST00000368078.8
calsequestrin 1
chrX_+_101391000 0.02 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr18_-_55587335 0.02 ENST00000638154.3
transcription factor 4
chr2_-_182522703 0.02 ENST00000410103.1
phosphodiesterase 1A
chr14_+_95535008 0.02 ENST00000331334.5
glutaredoxin 5
chrX_+_101390824 0.02 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr19_-_46634685 0.02 ENST00000300873.4
G protein subunit gamma 8
chr7_-_32299287 0.02 ENST00000396193.5
phosphodiesterase 1C
chr12_-_50222694 0.02 ENST00000552783.5
LIM domain and actin binding 1
chr11_-_26572254 0.02 ENST00000529533.6
mucin 15, cell surface associated
chr7_-_100119323 0.02 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TATA-box binding protein associated factor 6
chr2_+_168901290 0.02 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
glucose-6-phosphatase catalytic subunit 2
chr11_+_73787853 0.02 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr11_-_94973541 0.02 ENST00000279839.8
CWC15 spliceosome associated protein homolog
chr18_-_55588184 0.02 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr12_-_610407 0.02 ENST00000397265.7
ninjurin 2
chr8_-_22669084 0.02 ENST00000519513.5
ENST00000276416.11
ENST00000520292.1
ENST00000522268.1
bridging integrator 3
chr7_+_71132123 0.02 ENST00000333538.10
polypeptide N-acetylgalactosaminyltransferase 17
chr12_+_6904733 0.01 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr17_+_45161070 0.01 ENST00000593138.6
ENST00000586681.6
HEXIM P-TEFb complex subunit 2
chr19_+_6372757 0.01 ENST00000245812.8
alkB homolog 7
chr2_-_171433950 0.01 ENST00000375258.9
ENST00000442541.1
ENST00000392599.6
methyltransferase like 8
chr22_+_48576306 0.01 ENST00000358295.9
TAFA chemokine like family member 5
chr1_+_67685170 0.01 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr10_-_97445850 0.01 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chrX_-_152830721 0.01 ENST00000370277.5
centrin 2
chr19_+_1266653 0.01 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr11_-_72112669 0.01 ENST00000545944.5
ENST00000502597.2
anaphase promoting complex subunit 15
chr1_-_113904789 0.01 ENST00000369569.6
ENST00000369567.5
adaptor related protein complex 4 subunit beta 1
chr4_-_145180496 0.01 ENST00000447906.8
OTU deubiquitinase 4
chr18_+_44700796 0.01 ENST00000677130.1
SET binding protein 1
chr6_-_33192454 0.01 ENST00000395194.1
ENST00000341947.7
ENST00000374708.8
collagen type XI alpha 2 chain
chr12_-_52777343 0.00 ENST00000332411.2
keratin 76
chr3_+_2892199 0.00 ENST00000397459.6
contactin 4
chr11_+_76381303 0.00 ENST00000662483.1
ENST00000663165.1
ENST00000529331.2
ENST00000321844.6
ENST00000667240.1
GVQW motif containing 3
chr14_+_22271921 0.00 ENST00000390464.2
T cell receptor alpha variable 38-1
chr4_-_39977836 0.00 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr6_-_33289189 0.00 ENST00000374617.9
WD repeat domain 46
chr8_+_32721823 0.00 ENST00000539990.3
ENST00000519240.5
neuregulin 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.0 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)