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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for DRGX_PROP1

Z-value: 0.64

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
DRGX
ENSG00000165606.10 DRGX
PROP1
ENSG00000175325.2 PROP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROP1hg38_v1_chr5_-_177996242_1779962420.154.9e-01Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_91906280 4.75 ENST00000370399.6
TGFBR3
transforming growth factor beta receptor 3
chr1_+_84181630 3.06 ENST00000610457.1
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr2_-_55269038 2.38 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
MTIF2
mitochondrial translational initiation factor 2
chr9_-_123184233 1.88 ENST00000447404.6
STRBP
spermatid perinuclear RNA binding protein
chr6_-_75363003 1.83 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr3_-_18438767 1.67 ENST00000454909.6
SATB1
SATB homeobox 1
chr6_+_121437378 1.66 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr8_-_92095215 1.53 ENST00000360348.6
ENST00000520428.5
ENST00000518992.5
ENST00000520556.5
ENST00000518317.5
ENST00000521319.5
ENST00000521375.5
ENST00000518449.5
ENST00000613886.4
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr16_+_68085344 1.52 ENST00000575270.5
ENST00000346183.8
NFATC3
nuclear factor of activated T cells 3
chr3_-_125055987 1.44 ENST00000311127.9
HEG1
heart development protein with EGF like domains 1
chr16_+_68085420 1.43 ENST00000349223.9
NFATC3
nuclear factor of activated T cells 3
chr16_+_68085552 1.28 ENST00000329524.8
NFATC3
nuclear factor of activated T cells 3
chr1_+_84164962 1.26 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr6_+_116369837 1.24 ENST00000645988.1
DSE
dermatan sulfate epimerase
chr2_-_182427014 1.08 ENST00000409365.5
ENST00000351439.9
PDE1A
phosphodiesterase 1A
chr3_-_27722699 1.06 ENST00000461503.2
EOMES
eomesodermin
chr7_-_120858066 1.04 ENST00000222747.8
TSPAN12
tetraspanin 12
chr5_+_90640718 1.04 ENST00000640403.1
ADGRV1
adhesion G protein-coupled receptor V1
chr2_+_178320228 1.02 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr13_+_53028806 1.00 ENST00000219022.3
OLFM4
olfactomedin 4
chr10_+_68106109 0.98 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr16_-_67483541 0.96 ENST00000290953.3
AGRP
agouti related neuropeptide
chr12_+_19205294 0.96 ENST00000424268.5
PLEKHA5
pleckstrin homology domain containing A5
chr14_-_75069478 0.93 ENST00000555463.1
ACYP1
acylphosphatase 1
chr6_+_30914205 0.93 ENST00000672801.1
ENST00000321897.9
ENST00000625423.2
ENST00000676266.1
ENST00000428017.5
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr6_+_30914329 0.89 ENST00000541562.6
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr5_-_111976925 0.83 ENST00000395634.7
NREP
neuronal regeneration related protein
chr6_-_132659178 0.81 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr2_-_55334529 0.81 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
CCDC88A
coiled-coil domain containing 88A
chr9_+_2159672 0.81 ENST00000634343.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_155666718 0.77 ENST00000621234.4
ENST00000511108.5
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr8_-_85341659 0.76 ENST00000522389.5
CA1
carbonic anhydrase 1
chr10_-_49188380 0.75 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
TMEM273
transmembrane protein 273
chr1_-_93681829 0.74 ENST00000260502.11
BCAR3
BCAR3 adaptor protein, NSP family member
chr1_+_243256034 0.74 ENST00000366541.8
SDCCAG8
SHH signaling and ciliogenesis regulator SDCCAG8
chr18_-_55322215 0.71 ENST00000457482.7
TCF4
transcription factor 4
chr15_+_48191648 0.70 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
SLC12A1
CTXN2
solute carrier family 12 member 1
cortexin 2
chr15_-_52678560 0.70 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
FAM214A
family with sequence similarity 214 member A
chrX_+_77910656 0.68 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr6_-_111483700 0.68 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr1_+_14929734 0.68 ENST00000376028.8
ENST00000400798.6
KAZN
kazrin, periplakin interacting protein
chr1_+_248508073 0.68 ENST00000641804.1
OR2G6
olfactory receptor family 2 subfamily G member 6
chr16_+_24537693 0.68 ENST00000564314.5
ENST00000567686.5
RBBP6
RB binding protein 6, ubiquitin ligase
chr15_+_57219411 0.66 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
TCF12
transcription factor 12
chr8_+_26293112 0.64 ENST00000523925.5
ENST00000315985.7
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
chr1_+_77918128 0.63 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr2_-_58241259 0.63 ENST00000481670.2
ENST00000403676.5
ENST00000427708.6
ENST00000403295.7
ENST00000233741.9
ENST00000446381.5
ENST00000417361.1
ENST00000402135.7
ENST00000449070.5
FANCL
FA complementation group L
chr18_-_55321986 0.62 ENST00000570287.6
TCF4
transcription factor 4
chr1_-_21050952 0.60 ENST00000264211.12
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chr11_-_118252279 0.59 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
MPZL3
myelin protein zero like 3
chr9_+_2159850 0.58 ENST00000416751.2
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_218010202 0.56 ENST00000646520.1
TNS1
tensin 1
chr5_-_135954962 0.56 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
LECT2
leukocyte cell derived chemotaxin 2
chr5_-_55173173 0.54 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
CDC20B
cell division cycle 20B
chr12_-_118359639 0.53 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr4_-_99435396 0.49 ENST00000209665.8
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_46511511 0.49 ENST00000576629.5
LRRC37A2
leucine rich repeat containing 37 member A2
chr5_+_141192330 0.49 ENST00000239446.6
PCDHB10
protocadherin beta 10
chr8_+_12104389 0.49 ENST00000400085.7
ZNF705D
zinc finger protein 705D
chr8_-_17895487 0.48 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr5_+_36606355 0.48 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr12_-_7503744 0.47 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr3_-_27722316 0.46 ENST00000449599.4
EOMES
eomesodermin
chr9_+_74615582 0.46 ENST00000396204.2
RORB
RAR related orphan receptor B
chr8_-_17895403 0.45 ENST00000381840.5
ENST00000398054.5
FGL1
fibrinogen like 1
chr10_+_35175586 0.45 ENST00000494479.5
ENST00000463314.5
ENST00000342105.7
ENST00000495301.1
CREM
cAMP responsive element modulator
chr3_-_197573323 0.44 ENST00000358186.6
ENST00000431056.5
BDH1
3-hydroxybutyrate dehydrogenase 1
chr19_-_57974527 0.44 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr7_+_107583919 0.44 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr4_-_99435336 0.43 ENST00000437033.7
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr15_+_75336018 0.41 ENST00000567195.5
COMMD4
COMM domain containing 4
chr2_+_233691607 0.39 ENST00000373424.5
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chrX_+_120604084 0.38 ENST00000371317.10
MCTS1
MCTS1 re-initiation and release factor
chr5_-_56116946 0.38 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr22_-_28711931 0.37 ENST00000434810.5
ENST00000456369.5
CHEK2
checkpoint kinase 2
chrX_-_19799751 0.36 ENST00000379698.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr3_+_111674654 0.36 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
PLCXD2
phosphatidylinositol specific phospholipase C X domain containing 2
chr16_-_69339493 0.36 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
COG8
component of oligomeric golgi complex 8
chr12_-_7503841 0.35 ENST00000359156.8
CD163
CD163 molecule
chr9_+_133636355 0.35 ENST00000393056.8
DBH
dopamine beta-hydroxylase
chr9_+_72577369 0.34 ENST00000651183.1
TMC1
transmembrane channel like 1
chr8_-_56211257 0.34 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1
PLAG1 zinc finger
chr3_-_165837412 0.34 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
BCHE
butyrylcholinesterase
chr4_+_40196907 0.33 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
RHOH
ras homolog family member H
chr5_-_111758061 0.33 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
NREP
neuronal regeneration related protein
chr6_-_41071825 0.32 ENST00000468811.5
OARD1
O-acyl-ADP-ribose deacylase 1
chr22_-_28712136 0.31 ENST00000464581.6
CHEK2
checkpoint kinase 2
chr4_+_40197023 0.30 ENST00000381799.10
RHOH
ras homolog family member H
chr6_+_26087417 0.30 ENST00000357618.10
ENST00000309234.10
HFE
homeostatic iron regulator
chr20_+_33562306 0.30 ENST00000344201.7
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr3_+_111978996 0.29 ENST00000273359.8
ENST00000494817.1
ABHD10
abhydrolase domain containing 10, depalmitoylase
chr7_-_120857124 0.28 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
TSPAN12
tetraspanin 12
chr15_+_45252228 0.28 ENST00000560438.5
ENST00000347644.8
SLC28A2
solute carrier family 28 member 2
chr2_-_201739205 0.27 ENST00000681558.1
ENST00000681495.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr20_+_33235987 0.27 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr2_+_108621260 0.26 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr11_+_55262152 0.26 ENST00000417545.5
TRIM48
tripartite motif containing 48
chr1_+_244051275 0.25 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr22_-_28306645 0.25 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr11_+_108116688 0.25 ENST00000672284.1
ACAT1
acetyl-CoA acetyltransferase 1
chr19_+_55769118 0.25 ENST00000341750.5
RFPL4AL1
ret finger protein like 4A like 1
chr15_-_56243829 0.24 ENST00000559447.8
ENST00000673997.1
RFX7
regulatory factor X7
chr5_-_138139382 0.24 ENST00000265191.4
NME5
NME/NM23 family member 5
chr4_-_99435134 0.24 ENST00000476959.5
ENST00000482593.5
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_151175966 0.24 ENST00000441701.1
ENST00000295314.9
TMOD4
tropomodulin 4
chr14_-_21098848 0.24 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
ZNF219
zinc finger protein 219
chr7_+_148590760 0.23 ENST00000307003.3
C7orf33
chromosome 7 open reading frame 33
chr3_-_98522869 0.22 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
CLDND1
claudin domain containing 1
chr1_+_15341744 0.22 ENST00000444385.5
FHAD1
forkhead associated phosphopeptide binding domain 1
chr16_+_53099100 0.21 ENST00000565832.5
CHD9
chromodomain helicase DNA binding protein 9
chr6_-_69699124 0.21 ENST00000651675.1
LMBRD1
LMBR1 domain containing 1
chr12_-_118190510 0.20 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr6_+_72216442 0.20 ENST00000425662.6
ENST00000453976.6
RIMS1
regulating synaptic membrane exocytosis 1
chr7_+_90709530 0.20 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr17_-_73232218 0.20 ENST00000583024.1
ENST00000403627.7
ENST00000405159.7
ENST00000581110.1
FAM104A
family with sequence similarity 104 member A
chr5_-_135399863 0.20 ENST00000510038.1
ENST00000304332.8
MACROH2A1
macroH2A.1 histone
chr4_-_89029881 0.20 ENST00000506913.1
FAM13A
family with sequence similarity 13 member A
chr2_-_55010348 0.20 ENST00000394609.6
RTN4
reticulon 4
chr4_-_142305826 0.19 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr4_+_68447453 0.19 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr16_+_81645352 0.19 ENST00000398040.8
CMIP
c-Maf inducing protein
chr14_-_80959484 0.19 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
CEP128
centrosomal protein 128
chr17_+_70075215 0.19 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr12_+_75391078 0.19 ENST00000550916.6
ENST00000378692.7
ENST00000320460.8
ENST00000547164.1
GLIPR1L2
GLIPR1 like 2
chr2_-_171231314 0.18 ENST00000521943.5
TLK1
tousled like kinase 1
chr5_+_69565122 0.18 ENST00000507595.1
GTF2H2C
GTF2H2 family member C
chr3_-_151316795 0.18 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr3_-_12545499 0.18 ENST00000564146.4
MKRN2OS
MKRN2 opposite strand
chr6_+_27824084 0.18 ENST00000355057.3
H4C11
H4 clustered histone 11
chr7_-_123199960 0.17 ENST00000194130.7
SLC13A1
solute carrier family 13 member 1
chr1_+_74235377 0.17 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr7_+_142332182 0.17 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr17_+_70075317 0.16 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr15_+_75336053 0.16 ENST00000564815.5
ENST00000338995.10
ENST00000267935.13
COMMD4
COMM domain containing 4
chr20_+_31547367 0.15 ENST00000394552.3
MCTS2P
MCTS family member 2, pseudogene
chr11_-_124310837 0.15 ENST00000357821.2
OR8D1
olfactory receptor family 8 subfamily D member 1
chr12_-_10172117 0.15 ENST00000545927.5
ENST00000309539.8
ENST00000432556.6
ENST00000544577.5
OLR1
oxidized low density lipoprotein receptor 1
chr5_-_11589019 0.15 ENST00000511377.5
CTNND2
catenin delta 2
chr11_-_40294089 0.14 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr3_-_142029108 0.14 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr15_+_75336078 0.14 ENST00000567377.5
ENST00000562789.5
ENST00000568301.1
COMMD4
COMM domain containing 4
chr9_+_65700287 0.13 ENST00000489273.1
CBWD5
COBW domain containing 5
chr5_-_9630351 0.13 ENST00000382492.4
TAS2R1
taste 2 receptor member 1
chr12_-_11134644 0.13 ENST00000539585.1
TAS2R30
taste 2 receptor member 30
chr3_+_98168700 0.13 ENST00000383696.4
OR5H15
olfactory receptor family 5 subfamily H member 15
chr12_+_8513499 0.13 ENST00000299665.3
CLEC4D
C-type lectin domain family 4 member D
chr2_+_44275473 0.13 ENST00000260649.11
SLC3A1
solute carrier family 3 member 1
chr2_-_229921316 0.13 ENST00000428959.5
ENST00000675423.1
TRIP12
thyroid hormone receptor interactor 12
chr6_+_3258914 0.12 ENST00000438998.7
ENST00000419065.6
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome assembly chaperone 4
chrX_-_111410420 0.12 ENST00000371993.7
ENST00000680476.1
DCX
doublecortin
chr1_+_115029823 0.12 ENST00000256592.3
TSHB
thyroid stimulating hormone subunit beta
chr17_+_73232601 0.12 ENST00000359042.6
C17orf80
chromosome 17 open reading frame 80
chr11_-_96343170 0.12 ENST00000524717.6
MAML2
mastermind like transcriptional coactivator 2
chr1_-_186461089 0.12 ENST00000391997.3
PDC
phosducin
chr19_+_49513353 0.11 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr12_-_118359105 0.11 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr6_+_3258888 0.11 ENST00000380305.4
PSMG4
proteasome assembly chaperone 4
chr9_+_27524285 0.11 ENST00000276943.3
IFNK
interferon kappa
chr1_-_219613069 0.10 ENST00000367211.6
ENST00000651890.1
ZC3H11B
zinc finger CCCH-type containing 11B
chr17_+_73232400 0.10 ENST00000535032.7
ENST00000577615.5
ENST00000585109.5
C17orf80
chromosome 17 open reading frame 80
chr5_+_140827950 0.10 ENST00000378126.4
ENST00000529310.6
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr7_+_90709231 0.10 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chrY_-_6874027 0.09 ENST00000215479.10
AMELY
amelogenin Y-linked
chr11_-_58731968 0.09 ENST00000278400.3
GLYAT
glycine-N-acyltransferase
chr2_-_208129824 0.09 ENST00000282141.4
CRYGC
crystallin gamma C
chr3_-_33645253 0.09 ENST00000333778.10
CLASP2
cytoplasmic linker associated protein 2
chr2_+_165294031 0.08 ENST00000283256.10
SCN2A
sodium voltage-gated channel alpha subunit 2
chr17_+_77185210 0.08 ENST00000431431.6
SEC14L1
SEC14 like lipid binding 1
chr6_+_42929127 0.08 ENST00000394142.7
CNPY3
canopy FGF signaling regulator 3
chr3_-_157160751 0.08 ENST00000461804.5
CCNL1
cyclin L1
chr14_+_20110739 0.08 ENST00000641386.2
ENST00000641633.2
OR4K17
olfactory receptor family 4 subfamily K member 17
chr1_-_241999091 0.08 ENST00000357246.4
MAP1LC3C
microtubule associated protein 1 light chain 3 gamma
chr1_-_209784521 0.08 ENST00000294811.2
C1orf74
chromosome 1 open reading frame 74
chr7_+_90709816 0.07 ENST00000436577.3
CDK14
cyclin dependent kinase 14
chr5_-_175961324 0.07 ENST00000432305.6
ENST00000505969.1
THOC3
THO complex 3
chr3_-_98523013 0.06 ENST00000394181.6
ENST00000508902.5
ENST00000394180.6
CLDND1
claudin domain containing 1
chr4_-_142305935 0.06 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chrX_+_120604199 0.06 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chr4_+_48483324 0.06 ENST00000273861.5
SLC10A4
solute carrier family 10 member 4
chr3_+_12351493 0.05 ENST00000683699.1
PPARG
peroxisome proliferator activated receptor gamma
chr15_-_43106022 0.05 ENST00000627960.1
ENST00000290650.9
UBR1
ubiquitin protein ligase E3 component n-recognin 1
chrX_+_108044967 0.05 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr6_-_32941018 0.05 ENST00000418107.3
HLA-DMB
major histocompatibility complex, class II, DM beta
chr17_-_13017952 0.05 ENST00000578071.1
ENST00000426905.7
ENST00000395962.6
ENST00000338034.9
ENST00000583371.5
ELAC2
elaC ribonuclease Z 2
chr9_-_27005659 0.05 ENST00000380055.6
LRRC19
leucine rich repeat containing 19
chr12_-_110445540 0.05 ENST00000547365.1
ARPC3
actin related protein 2/3 complex subunit 3
chr17_+_55264952 0.05 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr11_+_89924064 0.04 ENST00000623787.3
TRIM49D2
tripartite motif containing 49D2
chr14_+_75069577 0.04 ENST00000238686.8
ZC2HC1C
zinc finger C2HC-type containing 1C
chr16_+_86566821 0.04 ENST00000649859.1
FOXC2
forkhead box C2
chr5_-_77638713 0.04 ENST00000306422.5
OTP
orthopedia homeobox
chr2_+_75646775 0.04 ENST00000393909.7
ENST00000358788.10
ENST00000409374.5
MRPL19
mitochondrial ribosomal protein L19
chrX_+_35919725 0.04 ENST00000297866.9
ENST00000378653.8
CFAP47
cilia and flagella associated protein 47
chr9_+_21440437 0.04 ENST00000276927.3
IFNA1
interferon alpha 1
chr3_+_42936859 0.04 ENST00000446977.2
ENST00000418176.1
ENSG00000273291.5
KRBOX1
novel protein
KRAB box domain containing 1
chr1_+_67166448 0.03 ENST00000347310.10
IL23R
interleukin 23 receptor
chr7_+_136868622 0.03 ENST00000680005.1
ENST00000445907.6
CHRM2
cholinergic receptor muscarinic 2
chr14_+_22516273 0.03 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr3_+_2892199 0.03 ENST00000397459.6
CNTN4
contactin 4
chr4_+_87832917 0.03 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.8 2.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.6 4.3 GO:0097338 response to clozapine(GO:0097338)
0.5 1.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.5 1.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.7 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.3 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.7 GO:0071284 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.2 0.7 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 4.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.8 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 1.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.0 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 1.0 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 2.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.2 GO:0038016 insulin receptor internalization(GO:0038016)
0.0 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 1.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.0 GO:1990180 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 4.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.3 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 4.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.7 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 0.7 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.2 1.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 1.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 2.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.3 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881) co-receptor binding(GO:0039706)
0.0 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.0 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 1.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 3.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase