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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for DUXA

Z-value: 0.89

Motif logo

Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
ENSG00000258873.3 DUXA

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_227813834 3.84 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr21_+_42199686 2.37 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr12_-_48865863 1.92 ENST00000309739.6
Rho family GTPase 1
chr1_+_12857086 1.76 ENST00000240189.2
PRAME family member 2
chr2_+_201129318 1.51 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr2_-_224947030 1.35 ENST00000409592.7
dedicator of cytokinesis 10
chr1_+_12773738 1.21 ENST00000357726.5
PRAME family member 12
chr11_-_4288083 1.16 ENST00000638166.1
SSU72 pseudogene 4
chr2_+_201129483 1.14 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr1_+_12791397 1.13 ENST00000332296.7
PRAME family member 1
chr8_-_6563409 1.11 ENST00000325203.9
angiopoietin 2
chr2_+_161136901 1.02 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr18_-_77127935 0.96 ENST00000581878.5
myelin basic protein
chr5_+_126423122 0.95 ENST00000515200.5
GRAM domain containing 2B
chr5_+_126423363 0.94 ENST00000285689.8
GRAM domain containing 2B
chr5_+_126423176 0.94 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr15_+_70936487 0.82 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr2_-_174764436 0.82 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
cholinergic receptor nicotinic alpha 1 subunit
chr1_-_13285154 0.82 ENST00000357367.6
ENST00000614831.1
PRAME family member 8
chr11_-_4242640 0.82 ENST00000640805.1
SSU72 pseudogene 2
chr11_+_4233288 0.80 ENST00000639584.1
SSU72 pseudogene 5
chr18_+_63887698 0.79 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr15_-_79971164 0.79 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr2_+_201129826 0.78 ENST00000457277.5
CASP8 and FADD like apoptosis regulator
chr6_+_135181323 0.76 ENST00000367814.8
MYB proto-oncogene, transcription factor
chr11_-_4339244 0.75 ENST00000524542.2
SSU72 pseudogene 7
chr3_-_196270540 0.72 ENST00000419333.5
phosphate cytidylyltransferase 1, choline, alpha
chr5_-_16916400 0.72 ENST00000513882.5
myosin X
chr6_+_55174508 0.71 ENST00000370862.4
hypocretin receptor 2
chr1_-_13201409 0.70 ENST00000625019.3
PRAME family member 13
chr5_+_141355003 0.70 ENST00000571252.3
ENST00000612927.1
protocadherin gamma subfamily A, 4
chr6_+_135181268 0.68 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr17_+_59331633 0.65 ENST00000312655.9
yippee like 2
chr6_-_169253835 0.64 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr12_-_51028234 0.63 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr2_-_174764407 0.63 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr12_-_91153149 0.63 ENST00000550758.1
decorin
chr10_-_48652493 0.62 ENST00000435790.6
Rho GTPase activating protein 22
chr12_+_25973748 0.60 ENST00000542865.5
Ras association domain family member 8
chr15_+_44427793 0.60 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTD small phosphatase like 2
chr2_-_231125032 0.60 ENST00000258400.4
5-hydroxytryptamine receptor 2B
chr17_-_41140487 0.57 ENST00000345847.4
keratin associated protein 4-6
chr11_+_49028823 0.56 ENST00000332682.9
tripartite motif containing 49B
chr16_+_57186281 0.56 ENST00000564435.5
ENST00000562959.1
ENST00000568505.6
ENST00000394420.9
ENST00000537866.5
ring finger and SPRY domain containing 1
chr7_+_135148041 0.56 ENST00000275767.3
transmembrane protein 140
chr5_-_116536458 0.55 ENST00000510263.5
semaphorin 6A
chr19_-_3061403 0.54 ENST00000586839.1
TLE family member 5, transcriptional modulator
chr6_+_26402237 0.54 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr7_-_138002017 0.54 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
cAMP responsive element binding protein 3 like 2
chr17_+_68525795 0.54 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr5_-_95961830 0.53 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr17_+_68515399 0.52 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr1_-_165445220 0.50 ENST00000619224.1
retinoid X receptor gamma
chr11_-_63490532 0.50 ENST00000538712.1
phospholipase A and acyltransferase 5
chr6_-_169250825 0.50 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr3_+_141402322 0.49 ENST00000510338.5
ENST00000504673.5
zinc finger and BTB domain containing 38
chr19_-_7058640 0.49 ENST00000333843.8
methyl-CpG binding domain protein 3 like 3
chr1_-_165445088 0.48 ENST00000359842.10
retinoid X receptor gamma
chr10_+_80537902 0.48 ENST00000339284.6
ENST00000646907.2
SH2 domain containing 4B
chr14_+_22147988 0.48 ENST00000390457.2
T cell receptor alpha variable 27
chr1_-_12945416 0.48 ENST00000415464.6
PRAME family member 6
chr8_+_69466617 0.48 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr19_-_12722547 0.48 ENST00000592287.5
transportin 2
chr18_+_63777773 0.47 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr1_-_12898270 0.47 ENST00000235347.4
PRAME family member 10
chr8_-_115492221 0.47 ENST00000518018.1
transcriptional repressor GATA binding 1
chr15_+_41286011 0.47 ENST00000661438.1
novel protein
chr19_-_6393205 0.46 ENST00000595047.5
general transcription factor IIF subunit 1
chr5_+_55024250 0.45 ENST00000231009.3
granzyme K
chr19_+_7049321 0.45 ENST00000381393.3
methyl-CpG binding domain protein 3 like 2
chr4_-_75724386 0.45 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP stress granule assembly factor 2
chr1_+_170532131 0.44 ENST00000367762.2
ENST00000367763.8
golgin, RAB6 interacting
chr17_-_81891562 0.43 ENST00000505490.3
Aly/REF export factor
chr4_-_75724362 0.43 ENST00000677583.1
G3BP stress granule assembly factor 2
chr11_-_48983826 0.42 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr2_+_169066994 0.42 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr6_+_26402289 0.42 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr1_+_13068677 0.42 ENST00000614839.4
PRAME family member 25
chr4_+_168631597 0.42 ENST00000504519.5
ENST00000512127.5
palladin, cytoskeletal associated protein
chr1_+_13303539 0.42 ENST00000437300.2
PRAME family member 33
chr11_-_89807220 0.41 ENST00000532501.2
tripartite motif containing 49
chr21_+_42653734 0.41 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
phosphodiesterase 9A
chr11_-_63491130 0.41 ENST00000540857.6
ENST00000539221.5
ENST00000301790.4
phospholipase A and acyltransferase 5
chr5_-_67196791 0.41 ENST00000256447.5
CD180 molecule
chr1_+_50103903 0.41 ENST00000371827.5
ELAV like RNA binding protein 4
chr5_+_173144442 0.40 ENST00000231668.13
ENST00000351486.10
ENST00000352523.10
ENST00000393770.4
BCL2 interacting protein 1
chr15_+_66453418 0.39 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr19_-_7040179 0.39 ENST00000381394.9
methyl-CpG binding domain protein 3 like 4
chr12_-_10807286 0.38 ENST00000240615.3
taste 2 receptor member 8
chr11_+_43311963 0.38 ENST00000534695.5
ENST00000455725.6
ENST00000531273.6
ENST00000420461.6
ENST00000378852.7
ENST00000534600.5
apoptosis inhibitor 5
chr19_-_45076465 0.37 ENST00000303809.7
zinc finger protein 296
chr11_+_4329865 0.37 ENST00000640302.1
SSU72 pseudogene 3
chrX_+_86714623 0.36 ENST00000484479.1
dachshund family transcription factor 2
chr14_+_100323332 0.36 ENST00000361529.5
ENST00000557052.1
solute carrier family 25 member 47
chr19_-_7021431 0.36 ENST00000636986.2
ENST00000637800.1
methyl-CpG binding domain protein 3 like 2B
chr19_-_14674886 0.35 ENST00000344373.8
ENST00000595472.1
adhesion G protein-coupled receptor E3
chr19_+_7030578 0.35 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr19_-_14674829 0.35 ENST00000443157.6
ENST00000253673.6
adhesion G protein-coupled receptor E3
chr10_+_84230660 0.34 ENST00000652073.1
retinal G protein coupled receptor
chr3_-_71360753 0.34 ENST00000648783.1
forkhead box P1
chr12_+_53938824 0.33 ENST00000243056.5
homeobox C13
chr12_+_110846960 0.33 ENST00000545036.5
ENST00000308208.10
coiled-coil domain containing 63
chr7_-_138001794 0.33 ENST00000616381.4
ENST00000620715.4
cAMP responsive element binding protein 3 like 2
chr5_+_141392616 0.33 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr11_-_73761051 0.33 ENST00000336083.8
ENST00000536566.5
ENST00000541588.5
ENST00000540771.5
ENST00000310653.10
RAB6A, member RAS oncogene family
chr12_+_18262730 0.33 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr1_+_13060769 0.32 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr7_+_142384328 0.32 ENST00000390361.3
T cell receptor beta variable 7-3
chr14_-_63318933 0.31 ENST00000621500.2
glycoprotein hormone subunit beta 5
chr1_+_13070853 0.30 ENST00000619661.2
PRAME family member 25
chr6_+_36029082 0.30 ENST00000472333.1
mitogen-activated protein kinase 14
chr1_+_13254212 0.30 ENST00000622421.2
PRAME family member 5
chr3_+_127193131 0.30 ENST00000624688.2
chromosome 3 open reading frame 56
chr11_-_13496018 0.30 ENST00000529816.1
parathyroid hormone
chr5_+_141192330 0.30 ENST00000239446.6
protocadherin beta 10
chr17_-_37542361 0.30 ENST00000614196.1
synergin gamma
chr4_-_69214743 0.29 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr2_+_172928165 0.29 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chr6_+_29306626 0.28 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr19_-_12722350 0.28 ENST00000356861.9
transportin 2
chr12_-_6635938 0.28 ENST00000329858.9
lysophosphatidic acid receptor 5
chr3_+_160225409 0.28 ENST00000326474.5
chromosome 3 open reading frame 80
chr4_-_110641920 0.28 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr19_-_45076504 0.28 ENST00000622376.1
zinc finger protein 296
chr5_+_122160168 0.27 ENST00000509403.6
ENST00000514637.1
novel zinc finger protein
chrX_+_1591590 0.27 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr14_+_67720842 0.27 ENST00000267502.3
retinol dehydrogenase 12
chr1_-_12947580 0.27 ENST00000376189.5
PRAME family member 6
chr12_-_23584600 0.27 ENST00000396007.6
SRY-box transcription factor 5
chr7_-_144264792 0.27 ENST00000641841.1
olfactory receptor family 2 subfamily A member 7
chr12_+_110847000 0.26 ENST00000552694.1
coiled-coil domain containing 63
chr1_+_224183197 0.26 ENST00000323699.9
delta 4-desaturase, sphingolipid 1
chr6_+_31586124 0.26 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr17_-_76737321 0.26 ENST00000359995.10
ENST00000508921.7
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
serine and arginine rich splicing factor 2
chr17_+_44957907 0.26 ENST00000678938.1
N-myristoyltransferase 1
chr11_+_114400030 0.25 ENST00000540163.5
RNA binding motif protein 7
chr1_+_13171848 0.25 ENST00000415919.3
PRAME family member 9
chr1_-_13347134 0.25 ENST00000334600.7
PRAME family member 14
chr7_-_126533850 0.25 ENST00000444921.3
glutamate metabotropic receptor 8
chr5_-_149944744 0.24 ENST00000255266.10
ENST00000617647.4
ENST00000613228.1
phosphodiesterase 6A
chr2_+_54115396 0.24 ENST00000406041.5
acylphosphatase 2
chr7_+_134646845 0.24 ENST00000344924.8
bisphosphoglycerate mutase
chr11_-_11353241 0.24 ENST00000528848.3
casein kinase 2 alpha 3
chr8_-_85341705 0.24 ENST00000517618.5
carbonic anhydrase 1
chr5_+_119629552 0.24 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chr12_-_109996216 0.24 ENST00000551209.5
ENST00000550186.5
GIT ArfGAP 2
chrX_+_54809060 0.24 ENST00000396224.1
MAGE family member D2
chr8_-_124565699 0.24 ENST00000519168.5
MTSS I-BAR domain containing 1
chr7_+_138076453 0.23 ENST00000242375.8
ENST00000411726.6
aldo-keto reductase family 1 member D1
chr1_-_12848720 0.23 ENST00000317869.7
heterogeneous nuclear ribonucleoprotein C like 1
chr6_-_49636832 0.23 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chr7_+_134646798 0.23 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr9_-_92424427 0.23 ENST00000375550.5
osteomodulin
chr6_-_27838362 0.23 ENST00000618958.2
H2A clustered histone 15
chr1_-_12886201 0.23 ENST00000235349.6
PRAME family member 4
chr10_+_88664439 0.23 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
lipase F, gastric type
chr6_+_63521738 0.22 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr2_-_212124901 0.22 ENST00000402597.6
erb-b2 receptor tyrosine kinase 4
chr15_-_43824675 0.22 ENST00000267812.4
microfibril associated protein 1
chr2_-_68871382 0.21 ENST00000295379.2
bone morphogenetic protein 10
chr2_-_86106121 0.21 ENST00000409681.1
RNA polymerase I subunit A
chr19_-_3761657 0.21 ENST00000316757.4
amyloid beta precursor protein binding family A member 3
chr14_-_75660816 0.21 ENST00000256319.7
ergosterol biosynthesis 28 homolog
chr6_-_65707214 0.21 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
eyes shut homolog
chr11_+_55883297 0.21 ENST00000449290.6
tripartite motif-containing 51
chr5_+_154858537 0.20 ENST00000517568.5
ENST00000524105.5
CCR4-NOT transcription complex subunit 8
chr2_+_54115437 0.20 ENST00000303536.8
ENST00000394666.7
acylphosphatase 2
chr17_+_76467597 0.20 ENST00000392492.8
aralkylamine N-acetyltransferase
chr4_+_70195719 0.20 ENST00000683306.1
odontogenic, ameloblast associated
chr5_+_141343818 0.20 ENST00000619750.1
ENST00000253812.8
protocadherin gamma subfamily A, 3
chr10_+_76318330 0.20 ENST00000496424.2
leucine rich melanocyte differentiation associated
chr5_+_142770367 0.20 ENST00000645722.2
ENST00000274498.9
Rho GTPase activating protein 26
chr6_+_31158518 0.19 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr3_-_94062881 0.19 ENST00000619045.1
dihydrofolate reductase 2
chr6_-_138499487 0.19 ENST00000343505.9
NHS like 1
chr4_-_108168919 0.19 ENST00000265165.6
lymphoid enhancer binding factor 1
chr4_+_69280472 0.19 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr10_-_110304894 0.19 ENST00000369603.10
survival motor neuron domain containing 1
chr6_+_26199509 0.19 ENST00000356530.5
H2B clustered histone 7
chr11_+_89924064 0.19 ENST00000623787.3
tripartite motif containing 49D2
chr21_+_46635595 0.19 ENST00000451211.6
ENST00000458387.6
ENST00000397638.6
ENST00000291705.11
ENST00000397637.5
ENST00000334494.8
ENST00000397628.5
ENST00000355680.8
ENST00000440086.5
protein arginine methyltransferase 2
chr4_+_94974984 0.19 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr10_-_67665642 0.18 ENST00000682945.1
ENST00000330298.6
ENST00000682758.1
catenin alpha 3
chr20_-_10420737 0.18 ENST00000649912.1
novel protein
chrX_-_72875974 0.18 ENST00000595412.5
DMRT like family C1
chr1_+_13061158 0.18 ENST00000681473.1
heterogeneous nuclear ribonucleoprotein C like 3
chr13_+_101489940 0.18 ENST00000376162.7
integrin subunit beta like 1
chr6_+_26365215 0.18 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr3_-_112845950 0.18 ENST00000398214.5
CD200 receptor 1 like
chr1_-_220046432 0.18 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr6_+_12717660 0.18 ENST00000674637.1
phosphatase and actin regulator 1
chr1_-_13165631 0.18 ENST00000323770.8
heterogeneous nuclear ribonucleoprotein C like 4
chr16_-_74666839 0.18 ENST00000576652.1
ENST00000572337.5
ENST00000571750.5
ENST00000572990.5
ENST00000361070.9
ring finger and WD repeat domain 3
chr9_-_35958154 0.17 ENST00000341959.2
olfactory receptor family 2 subfamily S member 2
chr19_-_54159696 0.17 ENST00000222224.4
leukocyte receptor cluster member 1
chr6_-_136550407 0.17 ENST00000354570.8
microtubule associated protein 7
chr4_-_108168950 0.17 ENST00000379951.6
lymphoid enhancer binding factor 1
chr1_-_161021096 0.17 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr4_-_8428424 0.17 ENST00000514423.1
ENST00000503233.5
acyl-CoA oxidase 3, pristanoyl
chr14_+_34993240 0.17 ENST00000677647.1
signal recognition particle 54

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.8 2.4 GO:0009720 detection of hormone stimulus(GO:0009720)
0.5 1.4 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4 1.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.3 3.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 1.0 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0015692 lead ion transport(GO:0015692)
0.1 0.6 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.7 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 1.9 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.4 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 1.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 1.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.2 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.4 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.2 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.1 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 1.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.7 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.4 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 3.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 1.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 2.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 1.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 3.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.3 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.6 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 4.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 3.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects