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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for E2F2_E2F5

Z-value: 1.11

Motif logo

Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.7 E2F2
ENSG00000133740.11 E2F5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg38_v1_chr1_-_23531206_23531241-0.536.2e-03Click!
E2F5hg38_v1_chr8_+_85209213_85209270-0.086.9e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_4909430 3.61 ENST00000620565.4
ENST00000613817.4
ENST00000624301.3
ENST00000650932.1
ubiquitin like with PHD and ring finger domains 1
chr10_+_60778331 2.14 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr10_+_60778490 2.00 ENST00000448257.6
ENST00000614696.4
cyclin dependent kinase 1
chr2_+_10123171 1.90 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chrX_+_24693879 1.82 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr4_+_54657918 1.78 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr11_-_19240936 1.71 ENST00000250024.9
E2F transcription factor 8
chr8_-_123396412 1.65 ENST00000287394.10
ATPase family AAA domain containing 2
chr11_-_19241598 1.55 ENST00000532666.1
ENST00000527884.5
ENST00000620009.4
E2F transcription factor 8
chr20_+_25407657 1.45 ENST00000262460.5
GINS complex subunit 1
chr3_+_127598400 1.45 ENST00000265056.12
minichromosome maintenance complex component 2
chr2_+_15940537 1.40 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr5_-_80654956 1.39 ENST00000439211.7
dihydrofolate reductase
chr4_-_148444674 1.37 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr10_+_123135938 1.36 ENST00000357878.7
H6 family homeobox 3
chr1_+_228458095 1.35 ENST00000620438.1
H2B.U histone 1
chr11_+_95789965 1.35 ENST00000537677.5
centrosomal protein 57
chr12_+_93572664 1.31 ENST00000551556.2
suppressor of cytokine signaling 2
chr22_+_35400115 1.28 ENST00000382011.9
ENST00000216122.9
ENST00000416905.1
minichromosome maintenance complex component 5
chr1_+_212035717 1.27 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr10_+_110567666 1.22 ENST00000361804.5
structural maintenance of chromosomes 3
chr5_-_80654552 1.17 ENST00000511032.5
ENST00000504396.1
ENST00000505337.5
dihydrofolate reductase
chr10_+_13161543 1.11 ENST00000378714.8
ENST00000479669.5
ENST00000484800.6
minichromosome maintenance 10 replication initiation factor
chr11_+_47215032 1.10 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
damage specific DNA binding protein 2
chr19_-_10194898 1.10 ENST00000359526.9
ENST00000679103.1
ENST00000676610.1
ENST00000678804.1
ENST00000679313.1
ENST00000677946.1
DNA methyltransferase 1
chr3_+_44761765 1.08 ENST00000326047.9
kinesin family member 15
chr6_+_27865308 1.07 ENST00000613174.2
H2A clustered histone 16
chr3_+_134795248 1.06 ENST00000398015.8
EPH receptor B1
chr6_-_52284677 1.05 ENST00000596288.7
ENST00000616552.4
ENST00000229854.12
ENST00000419835.8
minichromosome maintenance complex component 3
chr14_-_49688201 1.03 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chrX_+_123961696 0.97 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
stromal antigen 2
chr15_-_64381431 0.93 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr9_-_96418334 0.92 ENST00000375256.5
zinc finger protein 367
chr11_+_47214937 0.91 ENST00000256996.9
damage specific DNA binding protein 2
chrX_-_63755187 0.90 ENST00000635729.1
ENST00000623566.3
Cdc42 guanine nucleotide exchange factor 9
chr2_-_135876382 0.89 ENST00000264156.3
minichromosome maintenance complex component 6
chr5_+_36152077 0.88 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
S-phase kinase associated protein 2
chr10_-_129964240 0.87 ENST00000440978.2
ENST00000355311.10
EBF transcription factor 3
chr6_+_24775413 0.87 ENST00000378054.6
ENST00000620958.4
ENST00000476555.5
geminin DNA replication inhibitor
chr9_-_35079923 0.85 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr15_-_70892412 0.83 ENST00000249861.9
THAP domain containing 10
chr13_-_109786567 0.82 ENST00000375856.5
insulin receptor substrate 2
chr7_-_158704740 0.81 ENST00000409339.3
ENST00000356309.8
ENST00000409423.5
non-SMC condensin II complex subunit G2
chr1_-_25906457 0.78 ENST00000426559.6
stathmin 1
chr5_+_36151989 0.78 ENST00000274254.9
S-phase kinase associated protein 2
chrX_-_63755032 0.77 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr12_+_109098118 0.77 ENST00000336865.6
uracil DNA glycosylase
chr6_+_24774925 0.77 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chrX_-_63754664 0.74 ENST00000677315.1
ENST00000636392.1
ENST00000637040.1
ENST00000637178.1
ENST00000637557.1
ENST00000636048.1
ENST00000638021.1
ENST00000672513.1
novel protein
Cdc42 guanine nucleotide exchange factor 9
chr2_+_27275466 0.72 ENST00000404433.5
ENST00000406962.1
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr2_+_10122730 0.69 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr2_+_27275429 0.69 ENST00000420191.5
ENST00000296097.8
DnaJ heat shock protein family (Hsp40) member C5 gamma
chrX_-_136767322 0.68 ENST00000370620.5
Rac/Cdc42 guanine nucleotide exchange factor 6
chr10_-_24952573 0.67 ENST00000376378.5
ENST00000376376.3
ENST00000320152.11
phosphoribosyl transferase domain containing 1
chr2_+_27275461 0.66 ENST00000402462.5
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr4_+_153344671 0.66 ENST00000240488.8
meiotic nuclear divisions 1
chr1_-_212035513 0.64 ENST00000366992.7
ENST00000366993.7
ENST00000440600.6
ENST00000366994.8
integrator complex subunit 7
chr7_-_100101333 0.64 ENST00000303887.10
minichromosome maintenance complex component 7
chr7_-_105876477 0.63 ENST00000478915.1
ataxin 7 like 1
chr12_+_109097568 0.63 ENST00000242576.7
uracil DNA glycosylase
chr12_-_132687307 0.62 ENST00000535270.5
ENST00000320574.10
DNA polymerase epsilon, catalytic subunit
chr8_-_119855838 0.60 ENST00000313655.5
DNA replication and sister chromatid cohesion 1
chr7_+_26201705 0.60 ENST00000396386.7
ENST00000456948.5
ENST00000409747.5
chromobox 3
chr7_+_120951116 0.60 ENST00000431467.1
inhibitor of growth family member 3
chr13_+_32315071 0.59 ENST00000544455.6
BRCA2 DNA repair associated
chr2_+_47403116 0.57 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr4_+_153344633 0.57 ENST00000622785.4
meiotic nuclear divisions 1
chr13_+_113584683 0.57 ENST00000375370.10
transcription factor Dp-1
chr12_-_31591129 0.56 ENST00000389082.10
DENN domain containing 5B
chr12_+_48106094 0.55 ENST00000546755.5
ENST00000549366.5
ENST00000642730.1
ENST00000552792.5
phosphofructokinase, muscle
chr13_+_48303709 0.55 ENST00000646097.1
ENST00000650461.1
ENST00000267163.6
RB transcriptional corepressor 1
chr7_-_148884266 0.54 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr2_+_47403061 0.54 ENST00000543555.6
mutS homolog 2
chr20_-_5119945 0.54 ENST00000379143.10
proliferating cell nuclear antigen
chr3_+_134795277 0.54 ENST00000647596.1
EPH receptor B1
chr14_-_74084393 0.53 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr8_+_47960883 0.53 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chr5_+_134526100 0.53 ENST00000395003.5
jade family PHD finger 2
chr10_-_73247241 0.53 ENST00000372950.6
DnaJ heat shock protein family (Hsp40) member C9
chr13_+_32315468 0.53 ENST00000530893.6
ENST00000380152.8
BRCA2 DNA repair associated
chr9_-_76906090 0.51 ENST00000376718.8
prune homolog 2 with BCH domain
chr9_-_76906041 0.51 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr12_-_56333893 0.50 ENST00000547572.1
ENST00000257931.9
ENST00000610546.4
ENST00000440411.7
poly(A) specific ribonuclease subunit PAN2
chr15_+_66702219 0.50 ENST00000288840.10
SMAD family member 6
chr19_-_45406327 0.49 ENST00000593226.5
ENST00000418234.6
protein phosphatase 1 regulatory subunit 13 like
chr12_+_48105466 0.48 ENST00000549003.5
ENST00000550924.6
phosphofructokinase, muscle
chr16_+_30395400 0.48 ENST00000320159.2
ENST00000613509.2
zinc finger protein 48
chr8_+_47961028 0.47 ENST00000650216.1
minichromosome maintenance complex component 4
chr15_+_30625966 0.47 ENST00000428041.4
Rho GTPase activating protein 11B
chr3_+_41199389 0.47 ENST00000396185.8
ENST00000642986.1
ENST00000644678.1
ENST00000396183.7
ENST00000643031.1
ENST00000645982.1
ENST00000453024.6
catenin beta 1
chrX_+_102746059 0.46 ENST00000372735.1
basic helix-loop-helix family member b9
chr11_+_47565577 0.46 ENST00000326656.12
ENST00000326674.10
protein tyrosine phosphatase mitochondrial 1
chr15_+_40695423 0.46 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr7_-_94655993 0.45 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
sarcoglycan epsilon
chr6_+_27808163 0.44 ENST00000358739.4
H2A clustered histone 13
chr1_-_221742074 0.44 ENST00000366899.4
dual specificity phosphatase 10
chr9_+_104094557 0.44 ENST00000374787.7
structural maintenance of chromosomes 2
chr6_-_116254063 0.44 ENST00000420283.3
TSPY like 4
chr7_-_148884159 0.44 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chrX_+_102745965 0.44 ENST00000447531.5
ENST00000448867.1
basic helix-loop-helix family member b9
chr6_-_27814757 0.44 ENST00000333151.5
H2A clustered histone 14
chr7_+_101815904 0.43 ENST00000437600.9
ENST00000645010.1
ENST00000646649.1
cut like homeobox 1
chr12_-_56333693 0.43 ENST00000425394.7
ENST00000548043.5
poly(A) specific ribonuclease subunit PAN2
chr1_-_91021996 0.43 ENST00000337393.10
zinc finger protein 644
chrX_-_153470555 0.43 ENST00000370211.10
ENST00000330912.7
ENST00000334497.7
ENST00000338525.7
ENST00000370232.4
HAUS augmin like complex subunit 7
three prime repair exonuclease 2
chr22_-_28741783 0.42 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr11_+_9573633 0.41 ENST00000450114.7
WEE1 G2 checkpoint kinase
chr4_+_30720348 0.40 ENST00000361762.3
protocadherin 7
chr19_+_36214602 0.40 ENST00000456324.5
zinc finger protein 146
chr5_+_80654669 0.40 ENST00000667069.1
mutS homolog 3
chr15_+_44427793 0.40 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTD small phosphatase like 2
chr7_-_94656197 0.40 ENST00000643903.1
ENST00000644122.1
ENST00000447873.6
ENST00000644816.1
ENST00000644375.1
sarcoglycan epsilon
chr2_-_27263034 0.40 ENST00000233535.9
solute carrier family 30 member 3
chr7_-_94656160 0.40 ENST00000644609.1
ENST00000643272.1
ENST00000646137.1
ENST00000646098.1
ENST00000643193.1
ENST00000437425.7
ENST00000644551.1
ENST00000415788.3
sarcoglycan epsilon
chr2_-_46941760 0.40 ENST00000444761.6
ENST00000409147.1
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr2_-_231464353 0.39 ENST00000356936.6
nucleolin
chr22_-_37519528 0.38 ENST00000403299.5
caspase recruitment domain family member 10
chr1_-_35769958 0.38 ENST00000251195.9
ENST00000318121.8
claspin
chr16_-_10580577 0.37 ENST00000359543.8
epithelial membrane protein 2
chr11_+_65041203 0.37 ENST00000652489.1
ENST00000674184.1
SAC3 domain containing 1
chr22_-_37519349 0.37 ENST00000251973.10
caspase recruitment domain family member 10
chr2_+_17754116 0.37 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr2_+_47783172 0.37 ENST00000540021.6
mutS homolog 6
chr5_+_80654644 0.36 ENST00000265081.7
mutS homolog 3
chr5_-_36151853 0.36 ENST00000296603.5
LMBR1 domain containing 2
chr11_+_47565430 0.36 ENST00000426530.2
ENST00000534775.1
protein tyrosine phosphatase mitochondrial 1
chr15_+_47184076 0.36 ENST00000558014.5
semaphorin 6D
chr7_-_100101915 0.35 ENST00000621318.4
ENST00000343023.10
minichromosome maintenance complex component 7
chr2_-_17753792 0.35 ENST00000448223.7
ENST00000621152.4
ENST00000351948.8
structural maintenance of chromosomes 6
chrX_+_101098165 0.35 ENST00000684367.1
ENST00000423383.3
ENST00000682304.1
ENST00000682095.1
ENST00000403304.6
ENST00000435570.1
centromere protein I
chr17_+_60600178 0.35 ENST00000629650.2
ENST00000305921.8
protein phosphatase, Mg2+/Mn2+ dependent 1D
chr16_-_2980282 0.35 ENST00000572619.1
ENST00000574415.5
ENST00000440027.6
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr2_+_17753852 0.34 ENST00000317402.11
GEN1 Holliday junction 5' flap endonuclease
chr9_+_104094260 0.34 ENST00000286398.11
ENST00000440179.5
ENST00000374793.8
structural maintenance of chromosomes 2
chr16_-_2980406 0.34 ENST00000431515.6
ENST00000574385.5
ENST00000576268.1
ENST00000574730.5
ENST00000262300.13
ENST00000575632.5
ENST00000573944.5
protein kinase, membrane associated tyrosine/threonine 1
chr12_+_132687570 0.33 ENST00000317479.8
ENST00000543589.5
peroxisomal membrane protein 2
chr19_+_36215096 0.33 ENST00000443387.3
zinc finger protein 146
chr11_+_65040895 0.33 ENST00000531072.1
ENST00000398846.6
SAC3 domain containing 1
chr10_-_56361235 0.33 ENST00000373944.8
ENST00000361148.6
ENST00000395405.5
ZW10 interacting kinetochore protein
chr14_+_35826298 0.33 ENST00000216807.12
BRMS1 like transcriptional repressor
chr1_+_25272502 0.32 ENST00000328664.9
Rh blood group D antigen
chrX_+_153972729 0.32 ENST00000369982.5
transmembrane protein 187
chr13_+_45120493 0.32 ENST00000340473.8
general transcription factor IIF subunit 2
chr5_+_139293660 0.32 ENST00000512876.5
ENST00000513678.5
matrin 3
chr16_+_2969307 0.32 ENST00000576565.1
ENST00000318782.9
progestin and adipoQ receptor family member 4
chr8_-_97277890 0.32 ENST00000322128.5
TSPY like 5
chr16_+_2969270 0.31 ENST00000293978.12
progestin and adipoQ receptor family member 4
chrX_+_105822531 0.31 ENST00000243300.14
ENST00000536164.5
Nik related kinase
chr16_+_2969548 0.31 ENST00000572687.1
progestin and adipoQ receptor family member 4
chr3_-_53046031 0.31 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr1_+_25272479 0.31 ENST00000622561.4
Rh blood group D antigen
chr17_+_40287861 0.30 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr12_+_56128217 0.30 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr20_+_5950630 0.30 ENST00000378883.5
ENST00000378896.7
ENST00000378886.6
ENST00000610722.4
minichromosome maintenance 8 homologous recombination repair factor
chr5_+_57174016 0.30 ENST00000514387.6
ENST00000506184.7
GC-rich promoter binding protein 1
chr5_+_36876824 0.30 ENST00000652901.1
NIPBL cohesin loading factor
chr1_-_228457855 0.30 ENST00000366695.3
H2A.W histone
chr1_-_47314089 0.30 ENST00000360380.7
ENST00000371877.8
ENST00000447475.7
STIL centriolar assembly protein
chr2_-_46941710 0.29 ENST00000409207.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr2_+_173354820 0.29 ENST00000347703.7
ENST00000410101.7
ENST00000410019.3
ENST00000306721.8
cell division cycle associated 7
chr7_-_44848021 0.29 ENST00000349299.7
ENST00000521529.5
ENST00000350771.7
ENST00000222690.10
ENST00000381124.9
ENST00000437072.5
ENST00000446531.1
ENST00000308153.9
H2A.Z variant histone 2
chr7_-_6009072 0.28 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS1 homolog 2, mismatch repair system component
chr2_+_204545446 0.28 ENST00000406610.7
par-3 family cell polarity regulator beta
chr14_+_32934383 0.28 ENST00000551634.6
neuronal PAS domain protein 3
chr5_+_36876731 0.28 ENST00000282516.13
ENST00000448238.2
NIPBL cohesin loading factor
chr3_+_10026409 0.27 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr7_-_105876575 0.27 ENST00000318724.8
ENST00000419735.8
ataxin 7 like 1
chr10_-_73874568 0.27 ENST00000322635.7
ENST00000322680.7
ENST00000394762.7
ENST00000680035.1
calcium/calmodulin dependent protein kinase II gamma
chr9_+_97983332 0.27 ENST00000339399.5
acidic nuclear phosphoprotein 32 family member B
chr6_+_20401864 0.26 ENST00000346618.8
ENST00000613242.4
E2F transcription factor 3
chr7_-_6009019 0.26 ENST00000382321.5
ENST00000265849.12
PMS1 homolog 2, mismatch repair system component
chr14_-_95516616 0.26 ENST00000682763.1
spectrin repeat containing nuclear envelope family member 3
chr6_-_111483190 0.25 ENST00000368802.8
REV3 like, DNA directed polymerase zeta catalytic subunit
chr3_-_142149515 0.25 ENST00000475734.5
ENST00000467072.5
ENST00000489671.6
transcription factor Dp-2
chr3_+_41199462 0.25 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr22_+_30635746 0.25 ENST00000343605.5
solute carrier family 35 member E4
chr3_-_133661896 0.25 ENST00000260810.10
DNA topoisomerase II binding protein 1
chr19_+_13906255 0.25 ENST00000589606.5
coiled-coil and C2 domain containing 1A
chr9_+_79571767 0.25 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr19_+_35030438 0.25 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr6_-_27146841 0.24 ENST00000356950.2
H2B clustered histone 12
chr10_-_75401746 0.24 ENST00000372524.5
zinc finger protein 503
chr5_+_76083398 0.24 ENST00000322285.7
synaptic vesicle glycoprotein 2C
chr5_+_57173948 0.24 ENST00000424459.7
GC-rich promoter binding protein 1
chr1_-_91021455 0.24 ENST00000347275.9
ENST00000370440.5
zinc finger protein 644
chr7_+_87152531 0.24 ENST00000432366.6
ENST00000423590.6
ENST00000394703.9
cyclin D binding myb like transcription factor 1
chr7_+_94509793 0.24 ENST00000297273.9
CAS1 domain containing 1
chr1_-_205750167 0.23 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chrX_+_21940693 0.22 ENST00000404933.7
ENST00000379404.5
spermine synthase
chr2_+_74958635 0.22 ENST00000483063.2
DNA polymerase epsilon 4, accessory subunit
chr14_+_93207229 0.22 ENST00000554232.5
ENST00000556871.5
ENST00000013070.11
ENST00000555113.5
ubiquitin protein ligase E3 component n-recognin 7
chrX_+_48696719 0.22 ENST00000376687.4
suppressor of variegation 3-9 homolog 1
chr22_+_29306582 0.22 ENST00000616432.4
ENST00000416823.1
ENST00000428622.1
growth arrest specific 2 like 1
chr1_+_25272527 0.22 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr5_-_123423436 0.21 ENST00000328236.10
ENST00000306481.11
centrosomal protein 120
chr16_-_85688912 0.21 ENST00000253462.8
GINS complex subunit 2
chr8_+_67952028 0.21 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr5_+_139293728 0.21 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr5_-_55173173 0.21 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
cell division cycle 20B
chr10_-_73874502 0.20 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.9 2.6 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.7 3.0 GO:0006272 leading strand elongation(GO:0006272)
0.6 1.8 GO:0070662 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
0.5 1.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.5 4.1 GO:0090166 regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
0.5 4.7 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.4 4.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 1.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.4 1.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.3 1.0 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3 0.6 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.3 1.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.3 1.7 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.7 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.2 0.7 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 1.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 1.0 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 1.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.0 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.6 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.1 2.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 2.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.8 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.5 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 5.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.3 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 2.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 1.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.8 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 0.8 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.4 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 1.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.0 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 1.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.0 1.8 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183) histone H3-K9 dimethylation(GO:0036123)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 1.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.9 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.7 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 2.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 6.8 GO:0042555 MCM complex(GO:0042555)
0.4 1.7 GO:0000811 GINS complex(GO:0000811)
0.4 1.9 GO:0032302 MutSbeta complex(GO:0032302)
0.4 1.1 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.3 1.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 0.9 GO:0031251 PAN complex(GO:0031251)
0.3 1.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 3.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 1.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 0.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 1.6 GO:0000796 condensin complex(GO:0000796)
0.2 0.6 GO:0032116 SMC loading complex(GO:0032116)
0.2 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 1.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.5 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.8 GO:0032449 CBM complex(GO:0032449)
0.1 1.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.1 GO:0031298 replication fork protection complex(GO:0031298)
0.1 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 4.2 GO:0000791 euchromatin(GO:0000791)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.0 GO:0045120 pronucleus(GO:0045120)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 1.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0031493 nucleosomal histone binding(GO:0031493)
0.6 2.6 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.5 2.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.9 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.3 0.5 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.2 4.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.0 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.2 1.1 GO:0036033 mediator complex binding(GO:0036033)
0.2 4.1 GO:0035173 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) histone kinase activity(GO:0035173)
0.2 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 1.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 3.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 2.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.0 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.0 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.3 PID ATR PATHWAY ATR signaling pathway
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 6.5 PID E2F PATHWAY E2F transcription factor network
0.0 1.7 PID MYC PATHWAY C-MYC pathway
0.0 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 11.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.9 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.8 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.5 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.1 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.2 REACTOME MEIOSIS Genes involved in Meiosis
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.6 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines