ISMARA results: E2F3

Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation

Downloads

Results for E2F3

Z-value: 1.43

Motif logo

Transcription factors associated with E2F3

Gene Symbol	Gene ID	Gene Info
E2F3 Ensembl NCBI GeneCards UniProt	ENSG00000112242.15	E2F3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F3	hg38_v1_chr6_+_20403679_20403735, hg38_v1_chr6_+_20401864_20401921	0.18	4.0e-01	Click!

Activity profile of E2F3 motif

Sorted Z-values of E2F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F3

View svg image
View png image

Top targets:

Search:

Show entries

Promoter	Score	Transcript	Gene	Gene Info
chr20_+_59933761 Show fit	2.79	ENST00000358293.7	FAM217B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 217 member B
chr8_-_6978634 Show fit	2.33	ENST00000382679.2	DEFA1 Ensembl NCBI GeneCards UniProt Show fit	defensin alpha 1
chr12_+_116910935 Show fit	2.05	ENST00000652555.1 ENST00000455858.2	FBXW8 Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 8
chr16_-_88706262 Show fit	1.85	ENST00000562544.1	RNF166 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 166
chr21_+_44600597 Show fit	1.82	ENST00000609664.2	KRTAP10-7 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 10-7
chr6_-_27473058 Show fit	1.59	ENST00000683788.1 ENST00000211936.10	ZNF184 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 184
chr12_-_42483604 Show fit	1.38	ENST00000640132.1	PRICKLE1 Ensembl NCBI GeneCards UniProt Show fit	prickle planar cell polarity protein 1
chr12_-_47079926 Show fit	1.34	ENST00000429635.1 ENST00000550413.2	AMIGO2 Ensembl NCBI GeneCards UniProt Show fit	adhesion molecule with Ig like domain 2
chr5_+_80654669 Show fit	1.22	ENST00000667069.1	MSH3 Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 3
chr16_-_56519943 Show fit	1.15	ENST00000683875.1	BBS2 Ensembl NCBI GeneCards UniProt Show fit	Bardet-Biedl syndrome 2

Showing 1 to 10 of 200 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.1	2.9	GO:0016180	snRNA processing(GO:0016180)
0.0	2.8	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	2.7	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	2.5	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.1	2.4	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	2.4	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.8	2.3	GO:0035915	pore formation in membrane of other organism(GO:0035915)
0.5	2.3	GO:2000690	negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0	2.3	GO:0006270	DNA replication initiation(GO:0006270)

Showing 1 to 10 of 468 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.9	GO:0034464	BBSome(GO:0034464)
0.0	3.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	3.1	GO:0005814	centriole(GO:0005814)
0.6	2.9	GO:0032302	MutSbeta complex(GO:0032302)
0.2	2.4	GO:0032039	integrator complex(GO:0032039)
0.0	2.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	2.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	2.1	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	2.1	GO:0045095	keratin filament(GO:0045095)
0.3	2.0	GO:1990393	3M complex(GO:1990393)

Showing 1 to 10 of 193 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.6	2.9	GO:0032181	double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0	2.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.7	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	2.6	GO:0005179	hormone activity(GO:0005179)
0.5	2.1	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.1	1.9	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6	1.8	GO:0016979	lipoate-protein ligase activity(GO:0016979)
0.1	1.7	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	1.7	GO:0003954	NADH dehydrogenase activity(GO:0003954)

Showing 1 to 10 of 316 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.2	PID AURORA B PATHWAY	Aurora B signaling
0.0	2.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.0	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	1.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.8	PID ALK2 PATHWAY	ALK2 signaling events

Showing 1 to 10 of 29 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	12.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	3.0	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.2	2.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	2.8	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	2.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	2.6	REACTOME DEFENSINS	Genes involved in Defensins
0.0	2.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.4	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	2.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	2.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase

Showing 1 to 10 of 78 entries

Results for E2F3

Z-value: 1.43

Motif logo

Transcription factors associated with E2F3

Activity-expression correlation:

Activity profile of E2F3 motif

Sorted Z-values of E2F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F3

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: